冠心病抗栓酶治疗前后心电图40例分析

目的：探讨抗栓酶对冠心病患心电图及血液流变学的影响及其临床意义。方法：随机观察４０例患经用抗栓治疗前后心绞痛和心电图Ｓ－Ｔ段及血液流变学１０项指标的改变，并设４０例作对照。结果：治疗后，治疗组心绞痛恢复率１００％，明显高于对照组的８０％（Ｐ〈０．０１）；而Ｓ－Ｔ段恢复率为９１．７０％，与对照组７５％差异无显性（Ｐ〉０．０５）。治疗后治疗组血液流变学１０项指标均明显低于治疗前（Ｐ〈０．０１）；     

血液稀释对心肌缺血和缺血再灌注心室功能及血液流变学的影响

用四道生理记录仪和血液粘度检测法观测右旋糖酐４０等容稀释血液对犬心肌缺血和缺血再灌注后左心室功能和血液流变学状态的影响。２４只犬随机均分为４组：１组来缺血组；２组为缺血再灌注组；３组为缺血＋稀释组；４组缺血再灌注＋稀释组。结果：（１）血液流变学指标的改变：２组血液流变学状态于再灌注后较１组明显恶化，３，４组各项血液流变学指标在行血液稀释后较同期１，２组均明显改善。（２）心功能的改变：２组与再灌注     

血液稀释对心肌缺血和缺血再灌注心室功能及血液流变学的影响

用四道生理记录仪和血液粘度检测法观测右旋糖酐４０等容稀释血液对犬心肌缺血和缺血再灌注后左心室功能（ｐＬＶＳ、ｐ±ｄｐ／ｄｔ－ｍａｘ）和血液流变学状态的影响。２４只犬随机均分为４组：１组为缺血组；２组为缺血再灌注组；３组为缺血＋稀释组；４组为缺血再灌注＋稀释组。结果：①血液流变学指标的改变：２组血液流变学状态于再灌注后较１组明显恶化，３、４组各项血液流变学指标在行血液稀释后较同期１、２组均明显改善（Ｐ＜０．０５）。②心功能的改变：２组于再灌注后各项心功能指标较１组显著降低；３组稀释后ｐＬＶＳ、ｐ＋ｄｐ／ｄｔ－ｍａｘ较１组明显升高；４组稀释后ｐＬＶＳ、ｐ＋ｄｐ／ｄｔ－ｍａｘ较２组显著升高（Ｐ＜０．０５），较３组有升高的趋势，但无明显差异（Ｐ＞０．０５），而ｐ－ｄｐ／ｄｔ－ｍａｘ较２、３组均明显升高（Ｐ＜０．０５）。提示：①缺血再灌注后血液流变性将进一步恶化，这可能是再灌注后心功能损伤加重的原因之一；②等容血液稀释对心肌缺血和缺血再灌注后左心功能均有保护作用，但对后者改善作用更明显。     

等容血液稀释和维拉帕米对缺血再灌注心肌的保护

在犬的急性心肌缺血再灌注模型上，观察右旋糖酐４０等容血液稀释和维拉帕米注射液以及二者联合应用对心肌缺血再灌注损伤的防治作用。２４条犬随机分为４组：Ｉ组（对照组，ｎ＝６）、Ⅱ组（稀释组，ｎ＝６）、Ⅲ组（维拉帕米组，ｎ＝６）、Ⅳ组（稀释加维拉帕米组，ｎ＝６）。结果：①血液流变学指标改变：Ⅱ、Ⅳ组在血液稀释或给予维拉帕米后，血液流变学指标和Ⅰ、Ⅲ组相比明显改善（Ｐ〈０．０５）；②心功能改变：再灌注后，Ｉ     

丹红注射液对急性脑梗死患者血液流变学的临床分析

目的：分析丹红注射液（倍通 步长集团）对急性脑梗死患者血液流变学的影响。方法：随机选择60例脑梗死患者，随机分为2组，丹红注射液加用常规药物治疗30例（治疗组）；常规药物治疗组30例（对照组），观察两组治疗前后血液流变学变化。结果：治疗后两组血液流变学明显较治疗前降低（P〈0．01），但治疗组明显优于对照组，有明显差异（P〈0．01）。结论：丹红注射液治疗急性脑梗死能明显改善血液流变学。     

低能量氦氖激光血管内照射治疗高粘血症65例

目的：观察低能量氦氖激光血管内照射疗法（ＩＬＩＢ）对降低血粘度的治疗效果。方法：６５例用低能量氦氖激光治疗与４０例用低右,丹参静滴治疗对照观察高粘血症的血液流变学变化。结果：ＩＬＩＢ组治疗后血液流变学指标较治疗前均有明显下降,总有效率９５．３％,对照组有效率７５．０％,结论：ＩＬＩＢ疗法可有效降低血粘度。     

血液稀释疗法对严重烧伤患者血液流变学特性的影响

目的 通过在严重烧伤早期应用血液稀释疗法，研究机体血液流变学特性的改变。方法 选择伤后6h内住院的成年男性严重烧伤患者30例，随机分为对照组与观察组。对照组患者常规进行体液复苏治疗，观察组患者体液复苏治疗同对照组。并于伤后24h内在血流动力学监测下进行血液稀释。二组患者分别于伤后8，16，24，48h测定全血粘度、血细胞比容、红细胞变形指数、红细胞聚集指数等血液流变学指标。结果 ①观察组患者进行血液稀释后，心输出量(CO)、中心静脉压(CVP)、平均动脉压(MAP)、肺动脉楔嵌压(PAWP)等反映血流动力学的指标有所改善。②对照组患者全血粘度、血细胞比容、红细胞聚集指数等血液流变学指标伤后显著增加，红细胞变形指数显著下降。虽经补液治疗，上述指标仍于伤后24h达峰值，伤后48h才接近正常范围；而观察组患者进行血液稀释后上述指标明显改善，伤后24h基本达正常水平。结论 严重烧伤早期应用血液稀释疗法是安全的，能有效地改善血液流变学指标。从而大大提高体液复苏的效果，尽快恢复循环血容量，有效防治休克。     

再灌注前后稀释血液对兔缺血再灌注心肌SOD和丙二醛的影响

观察应用右旋糖酐４０分别于再灌注前后稀释血液对兔缺血再灌注心肌ＳＯＤ活性和丙二醛（ＭＤＡ）含量的影响。心肌缺血４５ｍｉｎ，再灌注１８０ｍｉｎ，复制急性心肌缺血再灌注模型。３０只兔随机分为３组，每组１０只。其中Ⅰ组（对照组）、Ⅱ组于再灌注后２０ｍｉｎ稀释血液；Ⅲ组于再灌注前２０ｍｉｎ稀释血液。结果：与Ⅰ组相比，Ⅱ组ＳＯＤ活性无明显变化，ＭＤＡ含量明显降低（Ｐ＜００５）；而Ⅲ组ＳＯＤ活性明显升高及ＭＤＡ含量显著降低（Ｐ＜００５）。提示：再灌注前后稀释血液对缺血再灌注心肌均有保护作用；而且再灌注前稀释血液的效果明显优于再灌注后稀释。     

等容血液稀释和维拉帕米对缺血再灌注心肌的保护

在犬的急性心肌缺血再灌注模型上，观察右旋糖酐４０等容血液稀释和维拉帕米注射液以及二者联合应用对心肌缺血再灌注损伤的防治作用。２４条犬随机分为４组：Ⅰ组（对照组，ｎ＝６）、Ⅱ组（稀释组，ｎ＝６）、Ⅲ组（维拉帕米组，ｎ＝６）、Ⅳ组（稀释加维拉帕米组，ｎ＝６）。结果：①血液流变学指标改变：Ⅱ、Ⅳ组在血液稀释或给予维拉帕米后，血液流变学指标和Ⅰ、Ⅲ组相比明显改善（Ｐ＜０．０５）；②心功能改变：再灌注后，Ⅰ组心功能指标明显恶化（Ｐ＜０．０５），Ⅱ组和Ⅲ组左室内收缩压力峰值（ｐＬＶＳ），左室内舒张末期压力（ｐＬＶＥＤ），左室内压力最大上升速率（＋ｄｐ／ｄｔ（ｍａｘ）），左室内压力最大下降速率（－ｄｐ／ｄｔ（ｍａｘ））与Ⅰ组相比明显改善（Ｐ＜０．０５）；Ⅳ组心功能指标则进一步好于Ⅱ、Ⅲ组（Ｐ＜０．０５）。提示：①右旋糖酐４０等容血液稀释能明显改善左心收缩和舒张功能，维拉帕米只能显著改善左室舒张功能；②二者合用能进一步改善左室收缩和舒张功能，缩小梗死范围     

血液稀释疗法治疗高粘血症40例观察

通过对４０例高粘滞血症病人的血液稀释治疗，观察血液稀释对高粘滞血症病人的治疗效果。利用正常献血员，其他治疗病人和本法治疗病人进行观察对照。查治疗前后的血液流变学及血脂，利用德国赫利氏低温低速离心机分离，除去多余组分，然后还输，同时用７０６代血浆补充血容量。结果：治疗组治疗前后的血液流变学指标及血脂检测值的变化差异有高度显著性（Ｐ＜００１），治疗组治疗前与正常人相比差异有高度显著性（Ｐ＜００１），而治疗后同正常人组相比则差异无显著性（Ｐ＞００５）。这表明血液成分稀释治疗高粘滞血症是一种有效的、切实可行的方法     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.