双目间接检眼镜直视下冷凝治疗孔源性视网膜脱离

目的: 探讨在双目间接检眼镜直视下冷凝治疗孔源性视网膜脱离的疗效。方法: 对86例(91眼)孔源性视网膜脱离患者,在双目间接检眼镜下查找裂孔并进行冷凝,外加压,根据视网膜脱离的具体情况决定环扎、放液或注入C₃F₈、SF₆气体。结果: 一次性手术后视网膜复位84眼,4眼二次手术后复位成功,另3眼需行玻璃体切割术。术后视力较术前明显提高(P<0.01)。结论: 间接立体检眼镜下冷凝治疗孔源性视网膜脱离,创伤小,效果好,值得推广应用。     

直接检眼镜直视下冷凝外路治疗视网膜脱离复位术

目的:探讨直接检眼镜直视下冷凝外路治疗视网膜脱离的手术方法与效果。方法:收集了2009年1月至2010年12月间,入住我院眼科行直接检眼镜直视下冷凝外路视网膜脱离术的资料完整的78例患者,具体描述了手术过程,并对手术的效果进行了分析。结果:所有患者经直接检眼镜直视下定位视网膜裂孔并实施冷凝,结合环扎、外加压治疗,视网膜复位率高。结论:在不具备双目间接检眼镜设备及技术的条件下,直接检眼镜直视下冷凝外路治疗视网膜脱离有直视下冷凝封闭视网膜裂孔的优势,这一手术方式对广大的基层医院有一定的借鉴作用。     

孔源性视网膜脱离的显微镜直视下手术治疗

目的:探讨孔源性视网膜脱离的显微镜直视下手术治疗的方法和效果.方法:对872例(882只眼)孔源性视网膜脱离病例在显微镜直视下行巩膜外环扎、硅压、放液、冷凝术,使视网膜复位.结果:视网膜裂孔封闭,包含复位837只眼(94.9%),再次手术后视网膜复位36只眼(4.1%),9只眼(1.0%),因患者拒绝再次手术,视网膜未能复位.结论:在手术显微镜直视下行孔源性视网膜脱离复位手术,双手操作准确而迅速,视网膜裂孔和变性区能清楚观察,显微镜直视下放液及作视网膜冷凝,同时核实硅胶填压的位置是否合适,且助手能同时观察和配合操作,缩短了手术时间,提高了手术成功率.     

间接眼底镜直视下孔源性视网膜脱离的外路治疗

目的 探讨在间接眼底镜直视下治疗孔源性视网膜脱离的临床效果.方法 对27例(27眼)孔源性视网膜脱离患者行巩膜扣带术治疗,术中采用在间接眼底镜直视下定位裂孔、巩膜外冷凝、放视网膜下液、巩膜扣带或环扎术,术后观察裂孔封闭及网膜复位情况.结果 术后随访3~12个月,27例(27眼)患者术后矫正视力改善22眼(81.48%)...     

显微镜在视网膜脱离手术中的临床应用

目的 对孔源性视网膜脱离行巩膜外加压应用显微镜直视下冷凝定位,并与直接检眼镜下定位肉眼下冷凝相比较观察疗效.方法 孔源性视网膜脱离59例(59眼)均由同一术者进行手术,均采用巩膜外加压排除视网膜下液,其中32眼应用显微镜直视下定位和冷凝,27例应用直接检眼镜定位进行同样手术,随访观察3个月～1年比较两组手术的定位准确率,手术时间,复位率.结果 应用显微镜组的定位率达到100％(32/32),一次性复位达到96.8％(31/32),明显优于直接检眼镜组74.0％(20/27),62.9％(17/27),x 2检验,P＜0.05.显微镜组裂孔定位和冷凝封闭的平均时间为(7.3±3.6 )min,低于检眼镜组的(10.5±3.8)min,t检验P＜0.05.结论 应用显微镜在视网膜脱离手术中,直视下定位冷凝与传统的直接检眼镜比较具有定位精确、冷凝程度准确、手术时间短、操作简便、疗效可靠的特点,有着重要的临床使用价值.     

双目间接检眼镜下行视网膜脱离复位术疗效分析

目的：比较双目间接镜直视下与传统直接检眼镜下行视网膜脱离（RD）复位术的临床疗效.方法： 将60例孔源性视网膜脱离患者,随机分为二组,每组30例30眼,第一组用双目间接检眼镜直视下行视网膜脱离复位术,第二组在直接检眼镜下进行手术.比较两种方法术后的解剖复位率和视功能恢复情况.结果：术后随访3个月～2年,第一组30例患者视网膜复位27例,解剖复位率90%,未复位3例,占10%,其中2例二次手术后成功复位,二次手术总计复位率96.6%.术后视力提高者27例,占90%.第二组30例,视网膜复位20例,占66.6%,未复位占10例点33.4%,术后视力提高20例,占66.6%.二者比较视网膜复位率及术后冷冻反应经χ2检验差异有显著意义（P〈0.05）.结论：双目间接检眼镜直视下行视网膜脱离（RD）复位术比传统直接检眼镜下行视网膜脱离（RD）复位术成功率高.     

显微镜直视下外路视网膜脱离手术探讨

孔源性视网膜脱离是因为视网膜裂孔引起的急性致盲性疾病。常规的视网膜脱离复位术,裂孔的定位及冷凝术、放液术均在双目间接检眼镜或直接检眼镜下完成。间接检眼镜具有倒像、放大倍数低、术中需反复取戴、不易掌握等缺点。而直接检眼镜又有视野小,受玻璃体影响大等缺点。我科2006年2月～2008年3月采用显微镜直视下外路视网膜脱离手术治疗,具有手术野清晰、放大倍数高、操作简便等优点,现将其报告如下。     

双目间接检眼镜下巩膜扣带术138例临床分析

尽管玻璃体手术的开展为复杂性视网膜脱离患者的治疗拓宽了治疗手段；但巩膜扣带术仍是孔源性视网膜脱离最常用的治疗方法。而应用双目问接检眼镜在直视下冷凝，使巩膜扣带术的成功率明显提高，并发症降低。我院在双目间接检眼镜下对138例（138眼）孔源性视网膜脱离患者实行巩膜扣带术，较以往直接检眼镜下手术时间缩短，疗效提高，现报     

间接检眼镜、显微镜行视网膜脱离复位术的临床比较

目的:观察并比较间接检眼镜及手术显微镜下视网膜脱离复位手术的临床疗效。方法:对68例(68眼)孔源性视网膜脱离患者分别在间接检眼镜、手术显微镜下行外路视网膜复位术,比较术后视力,视网膜复位率及并发症。结果:视网膜复位双目检眼镜组32眼,手术显微镜组31眼。视网膜复位患者视力均提高。结论:两种手术方式均可使视网膜复位,二者之间无明显统计学差异。     

直接检眼镜直视下行视网膜脱离手术

目的 介绍直接检眼镜直视下行视网膜脱离手术的优点及操作要点。方法 １５例孔源性视网膜脱离病人接受手术，均在直接检眼镜直视下裂孔定位后，经巩膜ＣＯ２冷凝或放视网膜下液，硅胶外加压或环扎。结果 术后随访平均０．５ａ，视网膜复侠率９４．９％。结论直视下进行网膜脱离手术，可准确地封闭裂孔。手术成功率高，并发症少，值得在临床上推广。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…