椎体硬化术加内固定治疗老年性骨质疏松症并脊柱骨折(附8例报告)

目的:探讨老年性骨质疏松症并脊柱多节段骨折的治疗方法.方法:8例老年性骨质疏松症并脊柱多节段骨折的患者均采用骨水泥椎体硬化,行脊柱长节段后路内固定,术后早期功能锻炼.结果:8例患者术后脊柱疼痛明显减轻,睡眠、运动明显改善,平均随访1年2个月,无内固定并发症及脊柱再骨折发生.结论:椎体硬化术加长节段脊柱后路内固定对老年性骨质疏松症并脊柱多节段骨折治疗效果好,可免除保守治疗的诸多并发症.     

退行性脊柱侧凸后路矫形术35例远期随访

目的 回顾退行性脊柱侧凸后路矫形术后的远期临床效果,分析晚期并发症的发生原因,探讨合理的应对措施.方法 回顾1997年9月至2002年9月,采用后路椎问融合器结合经椎弓根螺钉治疗退行性脊柱侧凸35例.按照Oswestry功能障碍指数(ODI)评价临床效果,影像学检查评价术后融合节段以及邻近节段病变,测量侧凸冠状位Cobb角、腰前凸角,脊柱冠状面平衡,并分析融合范围、脊柱力线与远期并发症的关系.结果 术后ODI为17.8～62.2(平均34.7),患者对手术的主观满意率为71.4%.13例患者发生远期并发症,发生率为37.1%,10例出现临床症状,6例进行翻修手术,4例拒绝再次手术.远期并发症包括:近端交界区侧凸4例、近端交界区后凸4例、近端椎体压缩骨折1例、融合区假关节形成1例、远端椎管狭窄2例,螺钉松动1例.交界性后凸与脊柱力线异常无明显关系,融合至L1及以下邻近节段病变发生率(9/18)明显高于融合至T12以上(4/17).结论 退行性脊柱侧凸后路矫形远期并发症较高,术前应仔细评价脊柱力线情况,为减少远期近端交界性侧凸,近端可融合至T12以上.     

一期内固定结合椎体成形术治疗脊柱跳跃性骨折合并骨质疏松症

目的 评价后路一期内固定结合椎体成形术治疗脊柱跳跃性骨折临床效果.方法 对15例(33椎)脊柱跳跃性骨折患者行一期后路钉棒内固定结合椎休成形术.术前行MRI或CT检查,在骨折累及三柱节段或神经损伤处行内固定,视椎管占位情况决定是否减压,对椎体后壁完整椎体行椎体成形术.结果 患者均获随访,时间5~24个月.无感染,伤口均一期愈合;无内固定失败;无继发后凸畸形加重,无迟发神经损伤;有神经损伤的患者均不有同程度的恢复.结论 一期后路内固定结合椎体成形术是治疗脊柱跳跃性骨折合并骨质疏松症的安全有效的方法.     

多节段胸腰椎骨折后路椎弓根钉治疗

目的探讨经后路椎弓根钉内固定治疗多节段胸腰椎骨折的手术指征及治疗效果。方法经后路切开复位、椎弓根内固定术治疗多节段胸腰椎骨折19例。其中邻节段两椎体骨折7例，跨一节段两椎体骨折5例，跨两节段以上两椎体骨折4例，跨三椎体以上骨折3例。结果经12～36个月随访，平均21．5个月。术后骨折椎体高度无明显丢失，有神经损伤的患者术后大部有所改善或恢复正常。未发现内固定物松动、断裂，无继发性脊柱后凸畸形加重。结论多节段胸腰椎骨折严重影响脊柱的稳定性，需及时手术治疗，经后路椎弓根钉棒系统复位内固定和有限椎管减压．可有效重建脊柱稳定性，改善神经功能；在警惕其他脏器合并伤的同时，可适当放宽手术指征。     

腰椎后路融合内固定术后近端邻近节段迟发性感染3例报告

<正>腰椎后路减压融合内固定术后出现手术部位急性感染或迟发性感染均比较常见,发生率为1.9%~4.4%~([1])。但是,腰椎后路融合术(PLIF)术后邻近节段出现迟发性感染的病例未见报道。我们诊治3例PLIF术后近端邻近椎间隙迟发感染的患者,报告如下。病例1:患者男,69岁。因L4/5 PLIF术后5年、T12~L5内固定术后1年,腰背部疼痛5个月加重10d入院。患     

脊柱侧凸后路矫形融合术后深部感染的治疗

背景背景:感染是脊柱侧凸手术后较严重的并发症之一。目的目的:探讨脊柱侧凸后路矫形融合术后深部感染的处理方法及治疗效果。方法方法:回顾分析2000年1月至2011年12月行脊柱后路矫形融合术的脊柱侧凸病例的临床资料,共2780例,深部感染患者19例。根据距首次手术时间分为早期感染和迟发感染,早期感染患者彻底清创后保留内固定物,迟发感染均取出内固定物,清创后一期闭合切口,并根据临床经验使用抗生素。结果结果:所有深部感染患者均有切口局部症状,19例感染患者中,男6例,女13例,特发性脊柱侧凸5例,先天性脊柱侧凸6例,成人脊柱侧凸6例,强直性脊柱炎后凸1例,经13-144个月随访,患者愈合良好,无感染复发情况。结论结论:局部脓肿、渗出或窦道常常为深部感染的诊断依据。对于脊柱侧凸术后深部感染患者清创是主要的,如无内固定松动等情况早期感染不一定必须取出内固定物。而对于迟发感染,植骨已融合患者可取出内固定物,根据情况使用抗生素。     

多节段椎管内肿瘤的外科治疗

目的探讨多节段椎管内肿瘤的特点、诊断、手术方法及临床效果。方法 15例多节段椎管内肿瘤患者行MRI检查示肿瘤组织压迫脊髓。均行后路常规手术入路切除肿瘤,行钉棒系统内固定。结果 15例均获得随访,时间12～50个月。术后影像学检查植骨融合良好。术后6个月按Frankel分级:C级2例恢复至D级1例、E级1例,D级13例恢复至E级10例,3例无恢复。结论经后路全椎板切除肿瘤治疗多节段椎管内肿瘤,患者术后症状大多数可以明显改善。多节段椎板切开术后应给予脊柱内固定,以保持脊柱的稳定性。     

先天性半椎体脊柱侧凸畸形的手术治疗

目的探讨治疗青少年先天性半椎体脊柱侧凸畸形的手术方法及治疗效果。方法对19例先天性半椎体脊柱侧凸患者，按照术式分为前路半椎体切除、短节段固定；前路切除半椎体、后路切除残余半椎体的关节突、椎板、矫形固定；后路半椎体切除、矫形固定。结果19例患者中侧凸平均矫正角度35．4°，矫正率63％，经6～24个月随访，2例出现交界区“附加”现象，其余病例半椎体切除区骨愈合良好，无断棒、脱钩等并发症，达到满意的矫形效果。结论小儿半椎体畸形应早期手术治疗。     

强直性脊柱炎合并多节段脊柱结核的外科治疗

目的探讨一期后路病灶清除植骨融合内固定治疗强直性脊柱炎（AS）合并多节段脊柱结核的临床疗效。方法对10例AS合并多节段脊柱结核患者行一期后路病灶清除植骨融合椎弓根螺钉内固定联合化疗治疗。结果 10例均获随访,时间6个月～3年。切口一期愈合,脊柱结核均治愈,无明显全身及局部并发症。在3～6个月均获得牢固愈合,患者全身状况良好。Frankel分级2例C级恢复至D级,4例D级恢复至E级。后凸畸形部分矫正,平均矫正8°±1°,未发现钉棒松动、脱位。结论 AS合并多节段脊柱结核采用后路病灶清除椎弓根螺钉内固定术联合化疗,可加强脊柱稳定,促进病灶吸收愈合,预防和矫正畸形,提高脊柱结核治愈率和植骨融合率。     

TSRH内固定治疗脊柱侧凸

目的　回顾性研究TSRH(TexasScottishRiteHospital)脊柱内固定系统在治疗脊柱侧凸的临床疗效。 方法　对 1998年 1月至 2 0 0 0年 12月手术治疗的 12 9例脊柱侧凸患者 ,总结其侧弯矫形、脊柱平衡、并发症及 3年以上的随访结果。根据手术方法不同 ,共分为 4组。A组 :单纯脊柱后路融合固定术 ;B组 :单纯脊柱前路融合固定术 ;C组 :分期前、后路融合固定术 ;D组 :Ⅰ期前、后路融合固定术。四组患者均应用TSRH内固定系统。手术时平均年龄 14 .2岁 (6～ 5 5岁 ) ,平均随访 34个月。结果　A组 :78例病人行单纯脊柱后路融合TSRH内固定 ,术后平均矫形率为6 3.4 %。随访 38个月 (2 4～ 5 0个月 ) ,平均矫形丢失 7°,矫形丢失率平均 9.5 %。本组并发症发生率为 12 .8% ,包括 3例脱钩 ,3例螺钉断裂 (共 6枚螺钉 ) ,1例术后侧弯失代偿 ,1例术后发生曲轴现象。B组 :2 2例患者行单纯脊柱前路融合、短节段TSRH内固定 ,平均矫形率为 74 .8%。平均随访 36个月 ,平均矫形率丢失 5 %。 2例发生一过性交感神经损伤。术后 6个月内均自然恢复。C组 :17例有 90°以上的侧弯 ,且Bending像上侧弯仍大于 7°的患者行前路松解 ,2～ 3周后再行后路融合TSRH内固定。本组平均手术时间 8.3h ,出血 935ml,输血 6 83ml,平均矫形 33.6°,矫     

Biomechanical comparison of semirigid junctional fixation techniques to prevent proximal junctional failure after thoracolumbar adult spinal deformity correction

BACKGROUND CONTEXTAdult spinal deformity patients treated operatively by long-segment instrumented spinal fusion are prone to develop proximal junctional kyphosis (PJK) and failure (PJF). A gradual transition in range of motion (ROM) at the proximal end of spinal instrumentation may reduce the incidence of PJK and PJF, however, previously evaluated techniques have not directly been compared.PURPOSETo determine the biomechanical characteristics of five different posterior spinal instrumentation techniques to achieve semirigid junctional fixation, or “topping-off,” between the rigid pedicle screw fixation (PSF) and the proximal uninstrumented spine.STUDY DESIGNBiomechanical cadaveric study.METHODSSeven fresh-frozen human cadaveric spine segments (T8–L3) were subjected to ex vivo pure moment loading in flexion-extension, lateral bending and axial rotation up to 5 Nm. The native condition, three-level PSF (T11–L2), PSF with supplemental transverse process hooks at T10 (TPH), and two sublaminar taping techniques (knotted and clamped) as one- (T10) or two-level (T9, T10) semirigid junctional fixation techniques were compared. The ROM and neutral zone (NZ) of the segments were normalized to the native condition. The linearity of the transition zones over three or four segments was determined through linear regression analysis.RESULTSAll techniques achieved a significantly reduced ROM at T10-T11 in flexion-extension and axial rotation relative to the PSF condition. Additionally, both two-level sublaminar taping techniques (CT2, KT2) had a significantly reduced ROM at T9-T10. One-level clamped sublaminar tape (CT1) had a significantly lower ROM and NZ compared with one-level knotted sublaminar tape (KT1) at T10-T11. Linear regression analysis showed the highest linear correlation between ROM and vertebral level for TPH and the lowest linear correlation for CT2.CONCLUSIONSAll studied semirigid junctional fixation techniques significantly reduced the ROM at the junctional levels and thus provide a more gradual transition than pedicle screws. TPH achieves the most linear transition over three vertebrae, whereas KT2 achieves that over four vertebrae. In contrast, CT2 effectively is a one-level semirigid junctional fixation technique with a shift in the upper rigid fixation level. Clamped sublaminar tape reduces the NZ greatly, whereas knotted sublaminar tape and TPH maintain a more physiologic NZ. Clinical validation is ultimately required to translate the biomechanics of various semirigid junctional fixation techniques into the clinical goal of reducing the incidence of proximal junctional kyphosis and failure.CLINICAL SIGNIFICANCEThe direct biomechanical comparison of multiple instrumentation techniques that aim to reduce the incidence of PJK after thoracolumbar spinal fusion surgery provides a basis upon which clinical studies could be designed. Furthermore, the data provided in this study can be used to further analyze the biomechanical effects of the studied techniques using finite element models to better predict their post-operative effectiveness.     

封闭负压引流联合灌注冲洗治疗四肢骨折内固定术后感染

目的 :探讨封闭负压引流联合灌注冲洗治疗四肢骨折内固定术后感染的临床疗效。方法 :自2010年3月至2015年6月,采用封闭负压引流联合灌注冲洗治疗10例四肢骨折内固定术后感染患者,男7例,女3例;年龄11~58岁,平均34.4岁;病程1~8个月,平均4.8个月。尺桡骨骨折术后感染4例,胫腓骨骨折术后感染3例,跟骨骨折术后感染2例,股骨骨折术后感染1例。10例中开放性骨折术后感染8例,闭合性骨折术后感染2例。采用封闭负压引流联合灌注冲洗,结合全身及局部抗生素使用,换药或植皮。观察感染创面控制愈合速度和时间、负压封闭引流敷料(VSD)更换次数及原感染灶有无复发等。结果:所有患者术后感染得到控制,伤口换药或植皮后愈合,无骨髓炎并发症发生,治疗时间29~45 d,平均38.4 d;更换VSD的次数1~4次,平均2.2次。10例患者均获得随访,时间1年,未见复发。结论:封闭负压引流联合灌注冲洗技术治疗四肢骨折术后感染能有效促进感染伤口的生长和愈合,缩短愈合时间,是治疗四肢骨折内固定术后感染的有效方法。     

Instrumentation techniques to prevent proximal junctional kyphosis and proximal junctional failure in adult spinal deformity correction—a systematic review of biomechanical studies

Background contextCorrection of adult spinal deformity (ASD) by long segment instrumented spinal fusion is an increasingly common surgical intervention. However, it is associated with high rates of complications and revision surgery, especially in the elderly patient population. The high construct stiffness of instrumented thoracolumbar spinal fusion has been postulated to lead to a higher incidence of proximal junctional kyphosis (PJK) and failure (PJF). Several cadaveric biomechanical studies have reported on surgical techniques to reduce the incidence of PJF/PJK. As yet, no overview has been made of these biomechanical studies.PurposeTo summarize the evidence of all biomechanical studies that have assessed techniques to reduce PJK/PJF following long segment instrumented spinal fusion in the ASD patient population.Study designA systematic review.MethodsEMBASE and MEDLINE databases were searched for human and animal cadaveric biomechanical studies investigating the effect of various surgical techniques to reduce PJK/PJF following long segment instrumented thoracolumbar spinal fusion in the adult patient population. Studied techniques, biomechanical test methods, range of motion (ROM), intervertebral disc pressure (IDP) and other relevant outcome parameters were documented.ResultsTwelve studies met the inclusion criteria. Four of these studies included non-human cadaveric material. One study investigated the prophylactic application of cement augmentation (vertebroplasty), whereas the remaining studies investigated semi-rigid junctional fixation techniques to achieve a gradual transition zone of forces at the proximal end of a fusion construct, so-called topping-off. An increased gradual transition zone in terms of ROM compared to pedicle screw constructs was demonstrated for sublaminar tethers, sublaminar tape, pretensioned suture loops, transverse hooks and laminar hooks. Furthermore, reduced IDP was found after the application of sublaminar tethers, suture loops, sublaminar tapes and laminar hooks. Finally, two-level prophylactic vertebroplasty resulted in a lower incidence of vertebral compression fractures in a flexion-compression experiment.ConclusionsA variety of techniques, involving either posterior semi-rigid junctional fixation or the reinforcement of vertebral bodies, has been biomechanically assessed. However, the low number of studies and variation in study protocols hampers direct comparison of different techniques. Furthermore, determination of what constitutes an optimal gradual transition zone and its translation to clinical practice, would aid comparison and further development of different semi-rigid junctional fixation techniques. Even though biomechanics are extremely important in the development of PJK/PJF, patient-specific factors should always be taken into account on a case-by-case basis when considering to apply a semi-rigid junctional fixation technique.     

Pre-existing vertebral fracture is a risk factor for postoperative proximal junctional fracture after adult spinal deformity surgery: A propensity score-matched analysis

BackgroundCorrective surgery for adult spinal deformity has recently been increasingly performed because of aging populations and advances in minimally invasive surgery. Low bone mineral density is a major contributor to proximal junctional kyphosis after spinal long fusion. Assessment for low bone mineral density ideally involves both dual energy X-ray absorptiometry and identification of pre-existing vertebral fractures, the latter, requiring only standard equipment, being performed more frequently. We therefore aimed to examine the impact of pre-existing vertebral fractures on the incidence of type 2 proximal junctional kyphosis, including proximal junctional fracture and failure, after corrective surgery for adult spinal deformity.MethodsWe performed a retrospective, single institution study of 106 women aged over 50 years who had undergone corrective long spinal fusion for severely symptomatic spinal deformity from 2014 to 2017. We allocated them to three groups (with and without pre-existing vertebral fractures and with severe [Grades 2–3 according to Genant et al.‘s classification] preexisting vertebral fractures) and used propensity score matching to minimize bias. The primary outcome was postoperative proximal junctional fracture and the secondary outcome proximal junctional kyphosis/failure.ResultsThe primary and secondary endpoints were achieved significantly more often in the 28 patients with than in the 78 without preexisting vertebral fractures (total 41). The former group was also significantly older and had greater pelvic tilt and fewer fused segments than those without vertebral fractures. After propensity score matching, the incidences of the endpoints did not differ with pre-existing vertebral fracture status; however, patients with severe vertebral fractures more frequently had proximal junctional fractures postoperatively. Postoperative improvements in health-related quality of life scores did not differ with pre-existing vertebral fracture status.ConclusionsSevere pre-existing vertebral fractures are a risk factor for proximal junctional fracture after correction of adult spinal deformity.     

前路椎体骨化物复合体前移融合术治疗颈椎椎管狭窄症合并巨大椎间盘突出

目的探讨前路椎体骨化物复合体前移融合术(ACAF)治疗颈椎椎管狭窄症合并巨大椎间盘突出的临床疗效。方法回顾性分析2017年5月—2018年9月采用ACAF治疗的10例颈椎椎管狭窄症合并巨大椎间盘突出患者临床资料。对患者手术前后临床表现、日本骨科学会(JOA)评分、MRI影像学变化及并发症发生情况进行总结分析。结果所有手术顺利完成。患者术后未发生神经系统症状加重、感染等并发症;术后脊髓功能恢复显著,四肢肌力和运动功能明显改善;随访期间未发生植骨块松动和内固定失败现象。所有患者术后复查MRI,提示减压充分,T2加权像示脑脊液充盈良好,硬膜囊压迹基本消失,但高信号区仍存在。结论 ACAF治疗颈椎椎管狭窄症合并巨大椎间盘突出效果确切,可显著改善患者的神经功能。     

Use of vertebroplasty to prevent proximal junctional fractures in adult deformity surgery: a biomechanical cadaveric study

Background contextVertebral compression fractures at the proximal junction are common complications of long spinal fusion surgeries that can contribute to the development of proximal junctional kyphosis or proximal junctional failure. To our knowledge, no biomechanical studies have addressed the effect of vertebral augmentation at the proximal junction.PurposeTo evaluate the effectiveness of prophylactic vertebroplasty in reducing the incidence of vertebral compression fractures at the proximal junction after a long spinal fusion in a cadaveric spine model.Study designBiomechanical cadaveric study.MethodsWe divided 18 cadaveric spine specimens into three groups of six spines each: a control group, a group treated with one-level prophylactic vertebroplasty at the upper instrumented vertebra, and a group treated with two-level prophylactic vertebroplasty at the upper instrumented vertebra and the supra-adjacent vertebra. In all spines, the pedicles were instrumented from L5 to T10. Using eccentric axial loading, the specimens were then compressed until failure. Failure was defined as a precipitous decrease in load with increasing compression. The effect of augmentation on load-to-failure was checked using linear regression. The effect of augmentation on incidence of adjacent fractures was checked using logistic regression. Differences at the level of p<.05 were considered significant. KyphX cement introducer was donated by Kyphon, and the pedicle screws were donated by DePuy.ResultsFractures occurred in 12 of 18 specimens: five in the control group, six in the one-level group, and only one in the two-level group; these differences were statistically significant.ConclusionsProphylactic vertebroplasty at the upper instrumented level and its supra-adjacent vertebra reduced the incidence of junctional fractures after long posterior spinal instrumentation in this axially loaded cadaveric model. Additional studies are necessary to determine if these results are translatable to clinical practice.     

股骨近端骨折髓内钉术后感染性骨不连的手术治疗

目的:探讨改良Ⅰ期手术治疗股骨近端骨折髓内钉术后感染性骨不连的方法和疗效。方法 :2010年6月至2015年6月采用改良Ⅰ期清创修复的手术方法治疗股骨近端骨折髓内钉术后感染性骨不连患者10例,其中男9例,女1例;年龄35~77岁。单纯股骨转子间骨折3例,股骨转子间合并股骨近端骨折2例,股骨转子下骨折5例。在彻底清创的基础上以股骨近端LISS钢板重新固定骨折端,用吻合血管游离腓骨移植加混有抗生素人工骨的自体松质骨植骨修复大段骨缺损,术后及早开始不负重关节功能锻炼。结果:所有患者获得随访,时间9~30个月。10例患者骨折均顺利愈合,随访期间无内固定断裂失效及感染复发病例,完全负重时间12~28周。末次随访采用Sanders创伤后髋关节评分标准评估术后髋关节功能:优7例,良2例,差1例。结论:改良Ⅰ期分次清创游离腓骨移植加载抗生素人工骨混合自体骨植骨LISS钢板固定的方法治疗股骨近端骨折髓内钉术后感染性骨不连,骨折愈合率高,髋关节功能恢复满意。在彻底清创的基础上综合运用控制感染与改善骨折愈合条件的各项措施是手术取得成功的关键。     

脊柱周围深部感染的外科治疗

目的：探讨脊柱周围深部感染的外科治疗方法及临床疗效。方法：自2015年1月至2018年1月收治脊柱周围深部感染患者7例,均为脊柱术后3周内发生的急性感染。其中男5例,女2例,年龄29～67岁,平均42岁。伤口有内植物4例,无内植物3例。感染确诊后,采用负压封闭引流辅助下彻底清创,局部放置载抗生素人工骨结合全身静脉滴注抗生素,并以血供丰富的组织瓣修复创面的方法治疗。所用组织瓣包括：椎旁肌推进肌瓣4例,胸腰筋膜瓣1例,背阔肌肌瓣1例,椎旁肌推进肌瓣联合胸腰筋膜瓣1例。结果：术后7例患者均获得随访,随访时间6～24个月,平均13.28个月。随访期间,有内植物的4例患者中,除1例腰椎融合的患者因术后感染复发而拆除内固定外,其余3例成功保留内植物。1例颈椎骨折脱位患者经背阔肌转位术后感染创面愈合,但供区皮瓣下出现积液,经过穿刺引流,局部加压包扎后治愈。其余5例创面获得Ⅰ期愈合,无感染复发、血肿、积液及伤口裂开等术后并发症发生。结论：脊柱周围深部感染是一种严重并发症,一旦确诊,应积极治疗。负压封闭引流辅助下彻底清创,局部放置载抗生素人工骨结合全身静滴抗生素,并以邻近组织瓣修复创面是治疗脊柱周围深部感染的一种有效术式。     

腰椎管狭窄症椎体间植骨融合术后急性切口深部感染的处理

目的:探讨下腰椎后路椎管减压、椎体间植骨融合(PLIF)术后急性切口深部感染的治疗方法与临床效果。方法:回顾性分析2005年12月至2010年12月收治的10例下腰椎PLIF术后急性切口深部感染治疗资料,其中男4例,女6例;年龄34～70岁,平均52.8岁。所有患者采用病灶清除、冲洗引流加抗生素应用治疗,比较手术前后VAS,ESR,CRP及下腰痛JOA评分变化,评估临床效果。结果:所有患者获随访,时间19～28个月,平均24个月。1例椎间隙感染者取出椎体间融合器,保留内固定螺钉,1例清创术后感染进行性加重,出现中枢感染猝死,其余8例术后恢复良好,下腰痛VAS评分由术前8.0±0.4下降至术后2.8±0.3;JOA评分由术前10.30±3.02改善至术后24.10±2.85。ESR由术前(85.0±17.0)mm/h下降至术后(14.0±6.0)mm/h;CRP由术前(73.5±14.3)mg/L下降至术后(5.1±1.1)mg/L;WBC由术前(11.1±1.8)×109/L下降至(7.4±0.5)×109/L。结论:腰椎管狭窄症PLIF术后切口深部感染早期行伤口切开、清创、病灶清除冲洗引流,保留内固定物,敏感抗生素应用可取得良好临床效果。术前对高危因素的预防处理尤为重要,对于确诊的腰椎后路深部感染患者,保守治疗无效,需早期手术治疗。