成人外伤性股骨头无菌坏死的介入治疗

目的：应用导管经旋股内，外动脉，闭孔动脉灌注治疗外伤性股骨头无菌坏死的研究，材料与方法，采用Ｓｅｌｄｉｎｇｅｒ‘ｓ穿刺超选择灌注溶通术，对３８例成人外伤性肥骨头无菌坏死患者经旋股内，外动脉，闭孔动脉灌注溶通药物，结果：介入治疗后３８例患才临床症状明显改善，髋关节疼痛，功能障碍等得到缓解或消失，治疗后Ｘ线复查坏死骨质均有不同程度的吸收，新骨形成及修复，结论：介入插管灌注溶药物法治疗成人外伤性股骨头无     

股骨头缺血性坏死的介入治疗（附50例分析）

目的：探讨股骨头缺血性坏死介入治疗的方法、疗效及术后康复治疗的措施。方法：股骨头缺血性坏死50例,单侧20例,双侧30例。采用Seldinger技术,对患侧的髂内动脉、旋股内动脉及旋股外动脉插管后,经导管灌注前列腺素E1、尿激酶和复方丹参注射液进行治疗。经导管灌注治疗2次者35例,3次者15例。术后康复治疗生活指导24-36个月,运用CR摄片及螺旋CT扫描及临床表现评价治疗效果。结果：50例患者临床症状均有明显改善。单侧20例股骨头缺血性坏死经介入治疗及术后康复治疗24-36个月,经CT扫描及CR摄片复查,病变稳定12例,明显好转8例;双侧患病的30例中,治疗后病变稳定16例,明显好转14例,总有效率100/%,其中稳定56/%（28/50）,明显好转44/%（22/50）。结论：股骨头缺血性坏死介入治疗是一种安全有效的方法,术后康复指导是确保取得治疗效果的必要措施。     

成人股骨头缺血性坏死合并骨髓水肿的介入治疗

目的探讨成人股骨头缺血性坏死合并骨髓水肿的介入治疗及其疗效观察。方法选择临床症状突出,经磁共振成像（MRI）检查证实的成人股骨头缺血性坏死合并骨髓水肿的患者20例,24髋,经对侧股动脉插管,分别超选择至患侧旋股内、外动脉,闭孔动脉开口,造影确定导管位置后,灌注溶栓剂、解痉剂及血管扩张剂等。结果①经2次或3次介入灌注术后与灌注前造影片对比,股骨头颈部血管增多、增粗、股骨头染色变深16例22髋,2例2髋改变不明显。②本组20例中有19例患者疼痛消失、明显减轻或缓解,总有效率占95％。③24个髋关节介入治疗前后活动范围均有不同程度改善。④16髋介入治疗后MRI对比,骨髓水肿明显减轻。结论介入灌注术治疗股骨头缺血性坏死合并骨髓水肿疗效确切。     

动脉内置管持续药物灌注治疗股骨头缺血性坏死临床应用

目的：探讨动脉内置管持续药物灌注治疗Ⅰ-Ⅲ期股骨头缺血性坏死的临床意义。方法：对31例（35髋）股骨头缺血性坏死行健侧或病变轻侧Seldinger技术穿刺，病变侧或病变轻侧的靶血管内经导管一次性注入尿激酶、复方丹参注射液、罂粟碱后，导管固定于病变侧或病变重侧，经微量药泵持续灌注罂粟碱、尿激酶、复方丹参注射液、低分子右旋糖苷。结果：Ⅰ—Ⅱ期病例仅一次治疗治愈，Ⅲ期病例明显改善症状。结论：动脉内置管持续药物灌注治疗股骨头缺血性坏死可在临床推广应用。     

超选择血管内介入治疗儿童股骨头骨骺缺血性坏死的疗效分析

目的探讨经导管超选择血管内介入治疗儿童股骨头骨骺缺血性坏死的临床疗效及影像学评价。方法对我院2010年9月至2011年4月收治的30例股骨头骨骺缺血性坏死患儿,采用Seldinger技术经对侧股动脉穿刺插管超选择行患侧旋股内、外动脉和闭孔动脉造影,分别采用尿激酶4～5千U、低分子右旋糖酐40 ml作局部灌注,再行造影,观察治疗后的影像学变化。21例需行第二次治疗。治疗结束后评定治疗效果,并行股骨头X线平片或CT、MR随访评估疗效。结果 DSA显示治疗后所有患者股骨头区血管计数较治疗前增加,股骨头染色增强;24例患髋疼痛症状明显减轻,跛行明显改善,治疗总有效率80%,无不良反应和并发症发生。影像学检查发现病侧股骨头塌陷变凸、死骨吸收、新骨形成。结论患儿骨质生长处于旺盛期,超选择血管内介入治疗股骨头骨骺缺血性坏死是一种创伤小、安全、并发症少、疗效肯定的方法,关节功能及股骨头形态均得到不同程度的改善。     

股骨头坏死介入治疗及临床分析(附138例报告)

目的探讨138例经旋股内外动脉插管灌注治疗股骨头缺血性坏死的治疗效果。方法采用Seldinger's超选择穿刺灌注溶通术,对138例不同原因引起的股骨头缺血性坏死患者经旋股内、外动脉及闭孔动脉灌注溶通药物。结果经介入治疗后138例患者髋关节疼痛及关节功能障碍均有不同程度的缓解或消失,治疗后1年影像学复查坏死骨质均有不同程度的吸收,新骨形成及修复。结论局部溶栓与扩张血管药联合使用,可显著改善临床症状,说明此法治疗对股骨头血流供应起到了改善作用。     

股骨头缺血坏死中西药联合溶栓的介入治疗

目的:应用导管经旋股内、外侧动脉,闭孔动脉灌注治疗股骨头坏死的临床研究。方法:采用seldinger’s穿刺超选择灌注溶通术,对66例股骨头坏死患者经旋股内、外侧动脉,闭孔动脉灌注溶通药物。结果:介入治疗后66例患者临床症状明显改善,髋关节疼痛、功能障碍等得到缓解或消失。治疗后X线片示坏死骨质均有不同程度吸收,新骨形成及修复。结论:介入插管中西药物联合灌注治疗股骨头缺血坏死具有较好的临床应用价值。     

酒精性股骨头坏死的介入治疗

目的　经导管灌注药物治疗酒精性股骨头坏死的研究。方法　采用Seldinger’s穿刺超选择灌注融通术 ,对 13例患者 ,2 2只酒精性坏死股骨头 ,将扩张血管、溶栓及改善微循环的药物直接注入缺血坏死股骨头的供血动脉内。旋股内、外动脉注入药物前 ,大腿根部用加压止血带捆绑并加压。结果　介入治疗后疼痛的缓解或消失占 10 0 % ,X线、CT复查均有不同程度的骨质修复 ,新骨形成。DSA显示股骨头细小动脉增多 ,供血小动脉增粗 ,静脉显影时间缩短。结论　介入插管治疗酒精性股骨头坏死具有一定价值。     

骨髓干细胞移植结合介入疗法治疗股骨头缺血性坏死

目的观察经动脉骨髓干细胞移植联合介入治疗股骨头缺血性坏死的疗效。方法选择经临床和影像学诊断为股骨头缺血性坏死患者32例（54髋）,采用Seldinger技术穿刺股动脉插管,将导管插入患侧髂内动脉,造影观察股骨头区血供情况,随后在髂内动脉注入溶栓药物、扩血管药物、改善微循环药物及自体干细胞悬液,治疗后随访观察临床症状变化及影像学表现。结果治疗后6个月,28例髋关节疼痛、功能障碍等不适得到缓解或消失,6例行髂内动脉造影显示股骨头区供血血管增粗,分支增多;2例X线片复查坏死骨质有不同程度新骨形成及修复。结论通过髂内动脉骨髓干细胞移植联合介入疗法治疗股骨头缺血性坏死是安全、有效、简便的方法。     

早期股骨头无菌坏死的治疗（附50例）分析

目的：研究经股动脉插管溶通术对股骨头缺血性坏死的疗效。方法：采用Seldinger穿刺技术经股动脉穿刺插管将5F—cobra导管超选择地送至旋股内、外侧动脉或闭孔动脉，先行股动脉DSA血管造影，观察患侧股骨头血供情况，造影后将导管插入病变血管，注入药物进行溶栓治疗。结果：治疗前后患髋股骨头血供情况明显改善，治疗前DSA血管造影显示：旋股内侧动脉分支部份狭窄或阻塞，治疗后血管记数明显增多，血管管经增宽，相互间吻合支增多，再通的血管显示良好。结论：介入治疗股骨头缺血性坏死能明显改善血供状况，创伤小、并发症少，血管再通率高，治疗疼痛症状明显改善，疗效显著。     

The role of interventional radiology in trauma

Introduction Interventional Radiology has evolved into a specialty having enormous input into the care of the traumatized patient.In all hospitals,regardless of size,the Interventional Radiologist must consider their relationships with the trauma service in order to     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Diagnóstico ecográfico del neumotórax

The ultrasonographic diagnosis of pneumothorax is based on the analysis of artifacts. It is possible to confirm or rule out pneumothorax by combining the following signs: lung sliding, the A and B lines, and the lung point. One fundamental advantage of lung ultrasonography is its easy access in any critical situation, especially in patients in the intensive care unit. For this reason, chest ultrasonography can be used as an alternative to plain-film X-rays and computed tomography in critical patients and in patients with normal plain films in whom pneumothorax is strongly suspected, as well as to evaluate the extent of the pneumothorax and monitor its evolution.     

Carbohydrate Supplementation during Exercise: Does It Help? How Much is Too Much?

KEY POINTS· Carbohydrate intake during exercise can delay the onset of fatigue and improve performance of prolonged exercise as well as exercise of shorter duration and greater intensity (e.g., continuous exercise lasting about 1h and intermittent high-intensity exercise), but the mechanisms by which performance is improved are different.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

磁共振DWI和动态增强鉴别颅底脊索瘤和侵袭性垂体瘤的应用

目的 探讨磁共振扩散加权成像(DWI)和动态增强在颅底脊索瘤和侵袭性垂体瘤(IPA)鉴别诊断中的应用价值.方法 搜集经手术病理证实且影像学有鞍区破坏的颅底脊索瘤患者15例、向鼻咽部侵犯的IPA患者20例.测量二者的表观扩散系数(ADC)值,绘制受试者工作特征曲线(ROC),分析动态增强曲线的类型,统计达峰时间(TTP)、增强峰值(EP)和最大对比增强率(MCER),分析各个参数在鉴别诊断中的价值.结果 颅底脊索瘤的ADC值为(1.274±0.07)×10-3mm2/s,高于IPA ADC值(0.672±0.03) ×10-3 mm2/s(P ＜0.001),ADC阈值为0.964×10-3mm2/s时,ROC曲线下面积为0.997,敏感度为93.3％,特异度为100％.颅底脊索瘤时间-信号强度曲线(TIC)Ⅰ型14例,TICⅢ型1例,此例TICⅢ型者TTP约40 s;IPA TIC Ⅰ型7例,TICⅢ型13例.颅底脊索瘤和IPA的EP、MCER差异均有统计学意义(P ＜0.001).结论 ADC值和TIC的类型及其相关参数(EP,MCER)有助于颅底脊索瘤和IPA之间的鉴别.     

Treatment of intrahepatic arteriovenous fistula in hepatocellular carcinoma with N-butyl-2-cyanoacrylate

Primary hepatocellular carcinoma (HCC) continues to be one of the most common malignancies with an incidence of approximately one million cases per year and a dismal prognosis; some authors have reported a median survival of 1 ～ 2 months after diagnosis. Although surgery remains the only hope for cure, few patients are candidates[1,2].     

U50,488H对正常及缺氧心肌细胞L型钙电流的作用

目的 探讨心脏阿片受体和β-受体相互作用的机制。方法 采用全细胞膜片钳技术,观察U50,488H(β-阿片受体选择性激动剂)对正常和缺氧心肌细胞L型钙电流的作用。结果 U50,488H剂量依赖性(0．1～100μmol／L)抑制正常心肌细胞的L型钙电流及异丙肾上腺素(0．1μmol／L)激动的钙电流,而细胞缺氧后,这一抑制作用减弱;U50,488H对Forskolin(10μmol／L)激动的L型钙电流无明显影响。结论 β-阿片受体对β-受体信号的负性调节作用在细胞缺氧后减弱,其作用位点可能发生于β-受体与腺苷酸环化酶环节之间。