基于工学结合的医学检验技术专业实践教学体系构建与实践

指出目前高职高专医学检验技术专业实践教学中存在的薄弱环节,以培养医学检验技术专业学生职业技能与职业素质为主线,构建基于工学结合的医学检验技术专业实践教学体系,有效培养学生职业综合素质,提高毕业生岗位适应能力。     

医学检验专业实践教学体系的建立与实践

目的:构建有利于创新意识和实践能力培养的医学检验专业实践教学体系.方法:通过分析实践教学存在的问题,制定构建原则,改革实践教学模式和教学方法,整合实践教学内容,建立了医学检验专业实践教学体系.同时,构建了医学检验专业实践教学体系质量管理与监控体系.结果:医学检验专业实践教学体系的建立,提高了教师教学积极性、创造性和教学能力,学生的综合素质显著提高.经过实践教学改革后的学生专业实验技能和临床岗位技能考核成绩均明显高于实践教学改革前(F=7.430-102.226,q=4.886-27.445,P<0.001).结论:医学检验专业实践教学体系的建立对培养学生的创新意识和实践能力具有重要意义.     

以能力培养为导向的医学检验技术实验教学体系建设探索

医学检验实验教学是提升医学检验专业学生应用能力的重要环节,是提高学生创新能力、动手操作能力的必要环节。潍坊医学院医学检验实验教学中心根据医学检验技术专业的学制特点和人才培养目标,提出改革医学检验技术实验体系的新思路,从校内课程改革、校外实践改革和评价考核方式等方面入手,通过实行检验特色层次化梯度实验教学、构建多元化实验教学模式、配套实验教材建设,结合岗位需求特点和专业特点,打造实习见习平台和社会服务实践平台及完善健全实验教学考核体系等措施,培养学生发现问题解决问题的能力,有效提高医学检验专业学生的实践操作能力与综合素质从而达到建设以能力培养为导向的医学检验技术实验教学体系的目的。     

基于工作过程的中药制剂技术实践教学体系的构建初探

指出目前高职高专中药制剂技术实践教学体系存在的问题,以培养学生职业技能与职业素质为主线,构建基于工作过程的中药制剂技术实践教学体系,培养学生职业综合素质,提高学生岗位就业能力。     

构建医学检验技术专业立体化递进式实践教学体系的思路

本科四年制医学检验技术专业旨在培养高级医学应用型人才，该宗旨的实现依赖于创新型实践教学课程体系的构建。本文结合基础实践、专业实践、职业技能实践、创新实践四大模块，改进传统实践教学体系中存在的问题，提出“3+1”立体化实践教学模式，以期适应医学检验技术专业的快速发展。     

高职、高专护理专业工学结合实践教学体系的研究

高职、高专护理专业工学结合实践教学体系是一种基于护理岗位能力,融入执业护士准入标准,以培养学生综合职业能力为主要目标的教学方式,相对于理论教学独立存在但又与之相辅相成,主要通过有计划地组织学生校内实训、专业社会实     

高职高专院校药学专业校内实训基地建设标准的研究

药学实训基地是药学专业学生职业技能训练的重要场所,其规范化建设是培养药学专业学生职业能力和职业素质的重要保证。本文研究了高职高专药学专业校内实训基地建设标准,并在安徽医学高等专科学校药学专业校内实训基地建设中进行了实践,取得了良好的效果。该标准的研究与实践成效对同类院校的药学校内实训基地建设具有借鉴意义。     

工学结合模式在医学检验专业课教学中的应用研究

目的评价工学结合模式在医学检验专业课教学中的应用效果。方法第二年专业课学习时,将我院2010级检验技术专业54名学生随机分为两组,一组(对照组)采用理论课后的校内实训,另一组(实验组)采用理论课后校内实训+课余临床实践(工学结合)。结果两组理论考试成绩除生物化学检验及血液学检验外,无显著性差异;技能考核实验组成绩明显高于对照组,有显著性差异(P<0.05)。结论工学结合模式有利于提高医学检验专业学生的操作技能,但对专业课的理论学习成绩提高不明显,可能与实施方法和评价方式有关。因此,在检验专业课教学中采用工学结合模式有待深入研究和改进。     

基于工学结合的医学检验技术专业实践教学目标体系的构建与实施

实践教学目标是实践教学应达到的标准,基于工学结合的实践教学目标体系要根据专业人才培养目标和培养规格要求,围绕职业岗位能力和职业素质培养进行构建;实践教学目标体系可通过在人才培养方案中明确职业岗位技能培养要求、以职业岗位能力培养为主线构建实践课程体系、将职业资格标准融入实践教学、以工学结合为切入点开展递进式实践教学活动和改革课程考核方式等途径实现。     

高职医学检验专业生化检验项目化教学的构建与实施

本文重点归纳了在医学检验专业技术教育领域中开展生化检验项目化教学的设想和实施步骤,包括开设生化检验项目化教学的原则、构建的内容体系、实施步骤,以及进行生化检验项目化教学在医学检验专业教学改革中的重要意义.有利于培养医学检验专业学生综合知识应用能力,提高职业素质和技能,进一步适应医学检验发展的需要.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.     

Possible Spread of adenovirus type 3 from poultry to humans ：indirect evidence from an outbreak in China

Objective:To explore the epidemiology and etiology for an outbreak of acute respiratory tract infection that occurred in one county of Jiangsu Province, China 2004. Methods: Only cases meeting the case definition were included in the study. We reviewed the medical records of the cases who were admitted to the local hospitals, interviewed cases by a standard questionnaire, and then described the epidemiotogic features and analyzed risk factors by means of a case-control study. We collected pharyngeal swab specimens and sent them to different laboratories for isolation and culture. The laboratory used different detection methods such as DIP, PCR, electron microscope examination and microneutralization assay, to identify and then type the positive specimens. Results:A total of 871 cases were reported during the period from April 18 to July 4,2004. The distribution of onset times presented two peaks, one in late May and another in middle June. The epidemic occurred mainly in the elementary and junior high schools in ten townships of one county, and the mean age of the cases was 12 years (range 7 months to 18 years). The course of the disease was acute, and was characterized by fever accompanied with sore throat and tonsillitis. The WBC count of cases was normal or elevated. The mean duration of illness was 5 days (range 2 to 12 days). No fatalities from illness were reported. A case-control study indicated that the possible risk factors were close contact with a case and/or poultry before onset and sharing of towels among members of the family. The typical CPE was observed through inoculating pharyngeal swab specimens into the HEP-2 cell cultures in different laboratories. An infection of adenovirus type 3 was verified by detecting positive specimens in different methods. Conclusion:This investigation demonstrated that the acute respiratory infection in cases was caused by adenovirus type 3. Cases occurred in over 70 schools in ten townships in 2004, and the route of transmission was possibly close contact with cases or droplet transmission.