油茶皂甙对鱼类造血功能的影响

变温动物的耗氧量随环境温度的升高而增加。油茶皂甙可破坏红细胞而影响氧的体内供应，从而削弱了机体对温变的适应能力。经皂甙水菠处理过的鱼，适温能力明显降低，待经一段恢复期后，这种能力仍可回升复原。可见油茶皂甙并未破坏机体的造血功能。     

时间温度对网织红细胞计数的影响分析

目的：观察末梢血不同染色时间，温度对网织红细胞计数的影响。方法：对200例体检人员末梢血样进行了4℃库温（18℃-25℃），37℃，于10min、15min、30min、60min分别采用目测法进行网织红细胞计数，对数据进行统计学处理。结果：在室温组不同处理时间均数间差别有显著性（P〈0．01），两两比较结果除30min与60min之间差别无明显意义（P〉0．05），其他各组间差别均有显著性（P〈0．01），37℃组方差分析结果不同处理时间之间差别无显著性（P〉0．05），37℃组各处理时间均数高于室温组（P〈0，01）。结论：不同染色时间和温度对网织红细胞计数有一定的影响，选用室温（18℃-25℃）染色30min为最佳条件。     

乌三颗粒抗肿瘤作用及对荷瘤小鼠造血功能的影响

目的：探讨乌三颗粒抗肿瘤作用及对荷瘤小鼠造血功能的影响，以寻找一种安全有效的新型抗肿瘤药物。方法：采用小鼠体内S180移植性肿瘤为模型，测定荷瘤小鼠抑瘤率，以判断其抗肿瘤作用；以荷瘤小鼠血象、骨髓细胞核分裂指数，体外造血干细胞集落形成为指标，观察该药对荷瘤小鼠造血功能的影响。结果：（1）乌三颗粒体内抑瘤率达38％－50％；（2）乌三颗粒组红细胞（RBC）计数、血红蛋白（HGB）含量均高于模型肿瘤组（P＜0．05）；（3）乌三颗粒组白细胞（WBC）计数、骨髓细胞核分裂指数、造血干细胞集落形成数，均高于西药化疗组（P＜0．05）。结论：乌三颗粒有一定的抗肿瘤作用，同时对荷瘤小鼠的造血功能有一定改善作用，且无降低白细胞的副作用，说明该药具有安全有效的优势。     

72例旅途精神病患者的生理指标分析

对７２例旅途精神病患者和９５例正常旅客进行机体生理指标的对照研究，以期探索旅途精神病的生理指标特征。结果表明，患者血红蛋白、血钾浓度低于对照组（Ｐ＜０．０１），白细胞计数、血糖浓度高于对照组（Ｐ＜０．０１）。按超载与非超载分组，发现超载组病人血红蛋白、血钾、血尿素氮低于正常人（Ｐ＜０．０１），白细胞计数、血糖、红细胞计数、红细胞压积高于正常人（Ｐ＜０．０１）；而非超载组病人血红蛋白、血钾低于正常人（Ｐ＜０．０１），白细胞计数、血糖、红细胞压积则显著高于正常人（Ｐ＜０．０１）。     

72例旅途精神病患者的生理指标分析

地７２例旅途精神病患者和９５例正常旅客进行机体生理指标的对照研究，以期探索旅途精神的生理指标特征。结果表明，患者血红蛋白，血钾浓度低于对照组（Ｐ〈０．０１），白细胞计数、血糖浓度同于对照组（Ｐ〈０．０１）。按超载与非超载分组，发现超载组病人血红蛋白，血钾、血尿素氮低于正常人（Ｐ〈０．０１），白细胞计数、血糖、红细胞计数、红细胞积高于正常人（Ｐ〈０．０１）；而非超载组病人血红蛋白、血钾低于正常人（Ｐ     

肝炎肝硬化合并缺铁性贫血患者的血液指标分析

目的：分析肝炎肝硬化合并缺铁性贫血（ IDA）患者的血液指标。方法选取失代偿期肝炎肝硬化合并有IDA（观察组）与肝炎肝硬化合并非IDA（对照组）患者各30例,分别测定血清铁蛋白、叶酸、维生素B12、凝血功能、血细胞分析、肝功能,并对各项结果进行比较。结果观察组血清铁蛋白低于对照组（ P＜0．05）、叶酸高于对照组（P＜0．05）、维生素B12与对照组比较差异无统计学意义（P＞0．05）;观察组丙氨酸氨基转移酶、γ－谷氨酰转肽酶均高于对照组（P＜0．05）,而门冬氨酸基转移酶、白蛋白、胆红素、碱性磷酸酶、胆汁酸与对照组比较差异无统计学意义（ P＞0．05）;观察组凝血酶原时间、凝血酶原活动度、凝血酶时间与对照组比较差异无统计学意义（P＞0．05）;观察组血红蛋白、平均红细胞体积、平均血红蛋白、平均血红蛋白浓度均低于对照组（P＜0．05）,红细胞压积、红细胞计数、白细胞计数、血小板计数与对照组比较差异无统计学意义（ P＞0．05）。结论血清铁蛋白、叶酸、血红蛋白、平均红细胞体积、平均血红蛋白、平均血红蛋白浓度的测定有助于诊断肝炎肝硬化患者合并IDA,肝炎肝硬化合并IDA患者的血液学异常与肝功能损害有密切关系。     

异叶青兰对高原实验家兔血液若干指标的影响

本文选用西安出生（海拔397米）纯种日本大耳白兔随机分为平原组、高原组和高原给药组，移居高原（海拔3900米）及应用抗低氧药物后，检测了三组实验动物外用血几项指标。结果表明：高原给药组红细胞（RBC）计数明显低于高原组，差异显著（P＜0．05）。此外，高原给药组血红蛋白（Hb）含量、红细胞比积（HCt）均值都低于高原组。结果提示：抗低氧药物──异叶青兰对家兔造血系统有一定的作用。     

烧伤患者红细胞血小板参数检测的临床意义

目的：探讨烧伤患者红细胞、血小板参数检测的临床意义。方法：根据烧伤严重程度惯用分类标准将70例中度以上烧伤患者分为三组：中度组28例、重度组25例和特重度组17例。采用日本东亚SysmexSF3000型全自动血液分析仪对三组烧伤后第1天、第3天、第7天、第15天、第20天的红细胞计数（RBC）、血红蛋白浓度（HGB）、红细胞压积（HCT）、平均红细胞体积（MCV）、平均红细胞血红蛋白含量（MCH）、平均红细胞血红蛋白浓度（MCHC）、红细胞体积分布宽度（RDW）、血小板计数（PLT）、血小板体积（MPV）、血小板体积分布宽度（PDW）进行检测，并进行动态观察。结果：三组烧伤后第1天、第3天、第7天、第15天、第20天RBC、HCT、HGB均明显高于对照组（P〈0．05，P〈0．01）；三组烧伤后第7天、第15天、第20天RDW均明显高于对照组（P〈0．05，P〈0．01）；三组烧伤后第3天、第7天PLT均明显低于对照组（P〈0．05，P〈0．01）；三组烧伤后第3天、第7天MPV、PDW均明显高于对照组（P〈0．05，P〈0．01）。结论：烧伤患者均存在不同程度的贫血；检测血小板参数可了解骨髓增生状态，对预后判断及治疗提供依据。     

参芪扶正注射液对化疗后小鼠造血功能影响的实验研究

目的 探讨参芪扶正注射液对化疗后小鼠造血功能的影响.方法 用5-氟尿嘧啶（5-FU）225 mg/kg腹腔注射复制骨髓抑制动物模型,治疗组给予参芪扶正注射液5 ml/kg,对照组给予同剂量生理盐水.治疗1周后,做血细胞计数、各系造血祖细胞集落（CFU-GM、CFU-E、CFU-MK）培养和骨髓病理检查.结果 参芪扶正注射液能升高外周血细胞计数：治疗组小鼠外周血的红细胞、白细胞和血小板计数均高于对照组（P〈0.05）.促进造血祖细胞增殖：治疗组小鼠的CFU-GM、CFU-E、CFU-MK集落数均大于对照组（P〈0.05）.改善骨髓抑制：骨髓病理检查对照组出现大片空白区,造血细胞稀少,而治疗组造血组织结构较完整,造血细胞量丰富.结论 化疗后小鼠在骨髓抑制、造血功能低下时,参芪扶正注射液能通过促进骨髓各系造血祖细胞的增殖,改善骨髓造血组织增生,从而促进血细胞的生成.     

聚乙二醇单修饰重组人粒细胞集落刺激因子对大鼠血液学及骨髓毒性的研究

目的：研究聚乙二醇单修饰重组人粒细胞集落刺激因子（PEG-rhG-CSF）对SD大鼠血液学和骨髓造血的影响,为其应用于临床治疗提供资料。方法：将SD大鼠随机分为3个实验组和1个对照组,分别sc不同剂量PEG-rhG-CSF和溶媒对照品,每周给药3次,连续给药3个月,恢复期2周。在给药和恢复期结束时进行血液学和骨髓检查,并做t-检验统计分析。结果：给药结束后,高中低剂量组血液白细胞计数显著升高（升高了7.8～28.2倍）,中性粒细胞计数明显增加（增加了2.5～3.9倍）,网织红细胞计数显著增加,淋巴细胞、嗜酸性粒和红细胞计数显著降低;同时,高剂量组血红蛋白量和血小板计数显著降低,高、中剂量红细胞比容显著增加;此外,高中低剂量骨髓红细胞系比例、中幼及晚幼红细胞比例显著降低,而成熟粒细胞比例显著升高（升高了29.1％～79.1％）,粒／红（M／E）比值也显著升高（最高增加1.3倍）。上述改变在停药2周后,均恢复到正常水平,与对照组比较均无显著性差异。结论：PEG-rhG-CSF具有明显的促进造血功能,临床可用于治疗肿瘤化疗引起的中性粒细胞减少症。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.