肝切除联合电子胆道镜治疗肝内胆管结石

目的:探讨肝切除联合电子胆道镜治疗肝内胆管结石的疗效.方法:回顾性分析2004年1月至2010年1月经肝切除并联合术中及术后电子胆道镜治疗的186例肝内胆管结石病例.结果:186例患者均行相应的肝叶(段)切除和术中胆道镜取石,59例(31.7%)术后有残留结石,术后胆道镜残余结石总取净率为88.1%(52/59),18...     

精准肝切除联合胆道镜治疗肝内胆管结石54例

目的:观察精准肝切除术联合术中胆道镜治疗肝内胆管结石的疗效。方法:回顾分析精准肝切除术联合术中胆管镜治疗肝内胆管结石54例患者的临床资料。结果:54例患者行病变相应的肝叶(段)切除联和术中胆道镜检取石;16例(29.6%)术后结石残留。结石残留的16例患者均行经T管窦道胆道镜取石术,其中14例取净结石,结石取净率为87.5%。54例患者总治愈率为96.3%(52/54),总残余结石率为3.7%(2/54)。结论:精准肝切除治疗肝内胆管结石,术中联合纤维胆道镜有助于术者选择正确的肝切除范围;同时胆道镜术后取石作为一种治疗手段能明显减少结石的残留率;从而有助于提高肝内胆管结石患者的疗效。     

肝内胆管结石的外科治疗

目的 探讨肝内胆管结石的外科治疗经验.方法 对我院1995年2月至2007年5月收治186例肝内胆管结石患者的临界床资料进行回顾性分析.结果 主要手术方式:胆管切开取石外引流术57例(30.6%),胆管切开取石空肠内引流58例(31.2%),肝叶或肝段切除加胆道内引流术40例(21.5%).手术并发症共19例,发生率为10.2%,总死亡率为(2.7%).结论 肝叶(段)切除术是治疗肝内胆管结石的极重要的外科手段,术后应用胆道镜取石,能有效地降低结石复发率.     

手术治疗肝内胆管结石并肝门胆管狭窄54例临床分析

目的探讨肝内胆管结石并肝门胆管狭窄的手术方法。方法回顾性分析2000年6月～2006年12月该院54例肝内胆管结石并肝门部胆管狭窄患者手术治疗的临床资料。结果全组54例,50例(92.6%)获得6个月～6年的随访,总优良率88.0%(44/50),胆道残石6例(11.1%),经1～5次胆道镜取净,术后切口感染3例(5.6%),膈下感染2例(3.7%),胆漏3例(5.6%),无手术死亡。结论合理选择肝叶(段)切除、肝门部狭窄胆管切开整形、肝胆管空肠Roux-en-Y吻合等手术方式,结合术中及术后纤维胆道镜取石是治疗肝内胆管结石并肝门部胆管狭窄的有效手段。     

肝切除联合术中纤维胆道镜治疗肝内胆管结石的临床分析(附85例病例报告)

目的 探讨肝切除联合术中纤维胆道镜治疗肝内胆管结石的疗效.方法 回顾性分析我院2002年至2007年经肝切除并配合术中及术后胆道镜处理的85例肝内胆管结石病例.结果 85例患者均行相应的肝叶(段)切除和术中胆道镜取石,11例(12.9%)术后有残余结石,术后胆道镜残余结石总取净率为81.8%,85例患者总治愈率为97.6%(83/85),总残石率为2.4%(2/85).结论 肝切除联合纤维胆道镜是治疗肝内胆管结石的一种有效方法,纤维胆道镜在处理肝内胆管结石中起到了重要作用.     

肝内胆管结石的手术治疗(附325例报告)

目的 探讨外科治疗肝内胆管结石的手术方法及临床价值。方法 回顾性分析5年来该科采用肝切除术联合术中胆道镜治疗肝内胆管结石的病例资料。结果 全组325例，其中单纯胆总管探查取石 T管引流46例；肝段(叶)切除 胆总管探查取石 T管引流104例；肝段(叶)切除 肝胆管探查取石 胆管空肠Y型吻合75例；肝段(叶)切除 肝胆管探查取石 狭窄胆管切开成形 胆管空肠Y型吻合95例；胆总管探查取石 胆总管十二指肠吻合5例。276例术中联合胆道镜取石，38例行术中胆道造影。术后残余结石46例，其中左内叶20例，右前叶17例，右后叶9例，经术后胆道镜结合液电碎石等处理治愈41例，再次手术5例。胆瘘12例，伤口感染15例，膈下脓肿4例，肺部感染5例，上消化道出血2例，均经积极非手术治疗痊愈。未发生手术死亡。结论 肝切除术联合术中胆道镜治疗肝内胆管结石能提高疗效、降低残石率、减少并发症，值得临床推广。     

手术治疗肝内胆管结石38例临床分析

目的:探讨肝内胆管结石的手术治疗方式及术后残石取出方法。方法:回顾性分析手术治疗的肝内胆管结石38例临床资料,根据结石的部位、大小、数量及肝胆系统的病理改变,分别选择不同的术式或联合手术,术中、术后配合纤维胆道镜取石。行肝叶(段)切除术+T管引流27例,肝叶(段)切除+胆管空肠Y型吻合术11例。结果:优良率达91.8%,术后残石9例(23.7%),经胆道镜等技术取石后残石1例(2.6%)。结论:利用现代影像技术,明确结石分布和肝胆系统的病理改变,选择合理的手术方式或联合手术,解除梗阻,去除病因,术中和术后配合胆道镜取石,提高疗效。降低残石率,避免再手术。     

术中胆道镜在238例规则性肝段切除治疗肝胆管结石患者中的应用

目的探讨术中胆道镜在规则性肝段切除治疗肝胆管结石患者中的应用价值.方法回顾性分析2000年1月至2004年12月采用规则性肝段切除术联合术中胆道镜治疗238例肝胆管结石患者的临床资料及远期疗效.结果术后并发症发生率为16.0%(38/238),死亡率为2.1%(5/238),单纯肝段切除肝内胆管结石清除率为36.1%(86/238),应用术中胆道镜取石治疗后肝内胆管结石清除率提高至87.4%(208/238),结合术后胆道镜取石治疗后胆管结石清除率达98.3%(234/238).220例患者平均随访39个月,95.9%(211/220)获得优良疗效,其中84.5%(186/220)完全无症状,11.4%(25/220)偶有轻度胆管炎发作;4.1%(9/220)患者因反复发作严重胆道感染而需进一步手术处理.结论在规则性肝段切除治疗肝胆管结石患者术中,应用胆道镜不仅有助于术者选择正确的肝切除,而且作为辅助的治疗手段,能明显减少结石的残留率,从而有助于提高肝胆管结石患者的手术疗效.     

肝左外叶切除大口胆肠内引流治疗肝内胆管结石合并胆管狭窄的疗效

目的 探讨肝左外叶切除大口胆肠内引流治疗肝内胆管结石合并胆管狭窄的疗效.方法 选择2007年6月-2009年5月肝内胆管结石合并胆管狭窄患者53例作为研究对象,对其临床资料进行回顾性分析.结果 本组53例患者均采用高位胆管切开+左肝外叶切除联合取石术+胆肠内引流术,术中使用纤维胆道镜取石42例,术后使用胆道镜取石11例.治疗效果优良49例,优良率为92.5%,术后出现肺部感染1例,切口感染3例,经积极抗炎治疗后均痊愈.术后随访发现残余结石3例,结石复发2例,残留结石者均用纤维胆道镜经T管窦道取净结石,2例结石复发者再次行胆管空肠吻合并应用纤维胆道镜取石.结论 肝左外叶切除、胆管切开取石术中使用纤维胆道镜取石联合大口胆肠内引流是目前治疗肝内胆管结石合并胆管狭窄的一种有效手术方法,值得临床推广应用.     

规则性肝段切除联合胆管镜取石治疗肝内胆管结石131例术式及疗效分析

目的探讨规则性肝段(叶)切除联合胆管镜取石治疗肝内胆管结石术式及远期疗效。方法回顾性分析1998年1月至2009年12月广安市人民医院采用规则性肝段(叶)切除联合胆管镜取石治疗131例肝内胆管结石患者的术后并发症,结石残留、复发及胆管感染等情况。结果131例患者术后恢复良好,无术后死亡。随访病例112例,随访期10个月至8年,其中症状消失93例(83.0%),术后结石残留8例(7.1%),复发7例(6.3%),胆管反复感染伴疼痛5例(4.5%)。结论规则性肝段(叶)切除联合胆管镜取石术安全有效,可降低残石、结石复发率,远期疗效较好,是目前治疗肝内胆管结石的可靠治疗方法之一。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.