双目间接检眼镜直视下冷凝治疗孔源性视网膜脱离

目的: 探讨在双目间接检眼镜直视下冷凝治疗孔源性视网膜脱离的疗效。方法: 对86例(91眼)孔源性视网膜脱离患者,在双目间接检眼镜下查找裂孔并进行冷凝,外加压,根据视网膜脱离的具体情况决定环扎、放液或注入C₃F₈、SF₆气体。结果: 一次性手术后视网膜复位84眼,4眼二次手术后复位成功,另3眼需行玻璃体切割术。术后视力较术前明显提高(P<0.01)。结论: 间接立体检眼镜下冷凝治疗孔源性视网膜脱离,创伤小,效果好,值得推广应用。     

直接检眼镜直视下冷凝外路治疗视网膜脱离复位术

目的:探讨直接检眼镜直视下冷凝外路治疗视网膜脱离的手术方法与效果。方法:收集了2009年1月至2010年12月间,入住我院眼科行直接检眼镜直视下冷凝外路视网膜脱离术的资料完整的78例患者,具体描述了手术过程,并对手术的效果进行了分析。结果:所有患者经直接检眼镜直视下定位视网膜裂孔并实施冷凝,结合环扎、外加压治疗,视网膜复位率高。结论:在不具备双目间接检眼镜设备及技术的条件下,直接检眼镜直视下冷凝外路治疗视网膜脱离有直视下冷凝封闭视网膜裂孔的优势,这一手术方式对广大的基层医院有一定的借鉴作用。     

孔源性视网膜脱离的显微镜直视下手术治疗

目的:探讨孔源性视网膜脱离的显微镜直视下手术治疗的方法和效果.方法:对872例(882只眼)孔源性视网膜脱离病例在显微镜直视下行巩膜外环扎、硅压、放液、冷凝术,使视网膜复位.结果:视网膜裂孔封闭,包含复位837只眼(94.9%),再次手术后视网膜复位36只眼(4.1%),9只眼(1.0%),因患者拒绝再次手术,视网膜未能复位.结论:在手术显微镜直视下行孔源性视网膜脱离复位手术,双手操作准确而迅速,视网膜裂孔和变性区能清楚观察,显微镜直视下放液及作视网膜冷凝,同时核实硅胶填压的位置是否合适,且助手能同时观察和配合操作,缩短了手术时间,提高了手术成功率.     

间接眼底镜直视下孔源性视网膜脱离的外路治疗

目的 探讨在间接眼底镜直视下治疗孔源性视网膜脱离的临床效果.方法 对27例(27眼)孔源性视网膜脱离患者行巩膜扣带术治疗,术中采用在间接眼底镜直视下定位裂孔、巩膜外冷凝、放视网膜下液、巩膜扣带或环扎术,术后观察裂孔封闭及网膜复位情况.结果 术后随访3~12个月,27例(27眼)患者术后矫正视力改善22眼(81.48%)...     

显微镜在视网膜脱离手术中的临床应用

目的 对孔源性视网膜脱离行巩膜外加压应用显微镜直视下冷凝定位,并与直接检眼镜下定位肉眼下冷凝相比较观察疗效.方法 孔源性视网膜脱离59例(59眼)均由同一术者进行手术,均采用巩膜外加压排除视网膜下液,其中32眼应用显微镜直视下定位和冷凝,27例应用直接检眼镜定位进行同样手术,随访观察3个月～1年比较两组手术的定位准确率,手术时间,复位率.结果 应用显微镜组的定位率达到100％(32/32),一次性复位达到96.8％(31/32),明显优于直接检眼镜组74.0％(20/27),62.9％(17/27),x 2检验,P＜0.05.显微镜组裂孔定位和冷凝封闭的平均时间为(7.3±3.6 )min,低于检眼镜组的(10.5±3.8)min,t检验P＜0.05.结论 应用显微镜在视网膜脱离手术中,直视下定位冷凝与传统的直接检眼镜比较具有定位精确、冷凝程度准确、手术时间短、操作简便、疗效可靠的特点,有着重要的临床使用价值.     

双目间接检眼镜下行视网膜脱离复位术疗效分析

目的：比较双目间接镜直视下与传统直接检眼镜下行视网膜脱离（RD）复位术的临床疗效.方法： 将60例孔源性视网膜脱离患者,随机分为二组,每组30例30眼,第一组用双目间接检眼镜直视下行视网膜脱离复位术,第二组在直接检眼镜下进行手术.比较两种方法术后的解剖复位率和视功能恢复情况.结果：术后随访3个月～2年,第一组30例患者视网膜复位27例,解剖复位率90%,未复位3例,占10%,其中2例二次手术后成功复位,二次手术总计复位率96.6%.术后视力提高者27例,占90%.第二组30例,视网膜复位20例,占66.6%,未复位占10例点33.4%,术后视力提高20例,占66.6%.二者比较视网膜复位率及术后冷冻反应经χ2检验差异有显著意义（P〈0.05）.结论：双目间接检眼镜直视下行视网膜脱离（RD）复位术比传统直接检眼镜下行视网膜脱离（RD）复位术成功率高.     

显微镜直视下外路视网膜脱离手术探讨

孔源性视网膜脱离是因为视网膜裂孔引起的急性致盲性疾病。常规的视网膜脱离复位术,裂孔的定位及冷凝术、放液术均在双目间接检眼镜或直接检眼镜下完成。间接检眼镜具有倒像、放大倍数低、术中需反复取戴、不易掌握等缺点。而直接检眼镜又有视野小,受玻璃体影响大等缺点。我科2006年2月～2008年3月采用显微镜直视下外路视网膜脱离手术治疗,具有手术野清晰、放大倍数高、操作简便等优点,现将其报告如下。     

双目间接检眼镜下巩膜扣带术138例临床分析

尽管玻璃体手术的开展为复杂性视网膜脱离患者的治疗拓宽了治疗手段；但巩膜扣带术仍是孔源性视网膜脱离最常用的治疗方法。而应用双目问接检眼镜在直视下冷凝，使巩膜扣带术的成功率明显提高，并发症降低。我院在双目间接检眼镜下对138例（138眼）孔源性视网膜脱离患者实行巩膜扣带术，较以往直接检眼镜下手术时间缩短，疗效提高，现报     

间接检眼镜、显微镜行视网膜脱离复位术的临床比较

目的:观察并比较间接检眼镜及手术显微镜下视网膜脱离复位手术的临床疗效。方法:对68例(68眼)孔源性视网膜脱离患者分别在间接检眼镜、手术显微镜下行外路视网膜复位术,比较术后视力,视网膜复位率及并发症。结果:视网膜复位双目检眼镜组32眼,手术显微镜组31眼。视网膜复位患者视力均提高。结论:两种手术方式均可使视网膜复位,二者之间无明显统计学差异。     

直接检眼镜直视下行视网膜脱离手术

目的 介绍直接检眼镜直视下行视网膜脱离手术的优点及操作要点。方法 １５例孔源性视网膜脱离病人接受手术，均在直接检眼镜直视下裂孔定位后，经巩膜ＣＯ２冷凝或放视网膜下液，硅胶外加压或环扎。结果 术后随访平均０．５ａ，视网膜复侠率９４．９％。结论直视下进行网膜脱离手术，可准确地封闭裂孔。手术成功率高，并发症少，值得在临床上推广。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.