脐血超氧化物歧化酶活性的变化及其临床意义

目的研究围生期窒息、妊娠高血压综合症、妊娠晚期羊水过少、胎盘老化等妊娠并发症者脐血超氧化物歧化酶 (SOD)活性的变化及其临床意义。方法采用邻苯三酚自氧化法 ,分别检测 30例围生期窒息、30例妊娠高血压综合症、30例妊娠晚期羊水过少、30例胎盘老化和 30例正常妊娠足月顺产的胎儿脐血SOD的活性。结果不同妊娠分娩状态胎儿脐血SOD活性的差异有显著性意义 (F =2 6 .85 32 ,P <0 .0 0 1 )。围生期窒息组和妊娠晚期羊水过少组脐血SOD活性高于对照组 ( 4 0 .1 4± 1 2 .6 1u/ml,39.4 0± 9.80u/ml和 2 9.39± 7.70u/ml,q’ =6 .4 0 6 8,P <0 .0 0 1 ,和 q’ =5 .96 5 8,P <0 .0 0 1 )。而妊娠高血压综合症和胎盘老化组脐血SOD活性低于对照组 ( 2 1 .89± 4 .6 9u/ml,2 30 6± 5 .5 4u/ml,q’ =4 .4 6 99,P>0 .0 0 1 ,和 q’ =3.772 6 ,P >0 .0 1 )。 结论脐血SOD活性的测定可作为诊断围生期窒息和妊娠并发症者继发胎盘功能减退的客观生化指标     

注意缺陷多动障碍儿童的智力结构及社会适应行为特点

①目的　探讨注意缺陷多动障碍 (ADHD)儿童智力结构及社会适应行为特点。②方法　选取ADHD病儿 4 8例 ,健康儿童 4 8例 ,利用韦氏学龄智力量表和社会适应行为评定量表评定其智力和社会适应能力 ,比较其智力结构和适应行为特点。③结果　智力方面ADHD病儿言语智商 (10 1.2 3± 7.4 5 )高于其操作智商 (89.72± 8.0 0 ) ,差异有显著性 (t=2 .2 4 1,P <0 .0 5 ) ,ADHD病儿言语、操作及总智商 (10 1.2 3± 7.4 5 ,89.72± 8.0 0 ,94 .12±10 .2 8)均低于对照组 (10 5 .4 6± 8.70 ,10 2 .85± 9.36 ,10 4 .2 0± 8.5 7) ,差异有显著性 (t=2 .0 12～ 2 .5 4 7,P <0 .0 5 ) ;不分心因子和获得因子得分 (16 .10± 3.86 ,2 5 .4 7± 5 .0 1)低于对照组 (2 0 .0 0± 3.94 ,2 9.33± 4 .4 6 ) ,差异有显著性(t=2 .76 4 ,3.2 2 3,P <0 .0 1)。社会适应方面ADHD病儿独立功能因子得分和认知因子得分 (6 1.2 0± 6 .14 ,5 6 .80± 5 .86 )高于对照组 (5 1.6 6± 5 .4 7,4 8.2 4± 4 .98) ,差异有显著性 (t=2 .5 6 0 ,2 .5 89,P <0 .0 5 ) ,而社会 自制因子得分 (40 .32± 6 .2 2 )显著低于对照组 (5 7.86± 6 .0 3) (t =2 .4 12 ,P <0 .0 5 )。④结论ADHD病儿智力结构和社会适应能力存在缺陷 ,积极防治对保证其智力发     

护士长人格特征和行为类型调查分析

1目的　了解护士长人格特征和行为类型。 2方法　对 35 6名护士长进行了艾森克个性问卷和行为类型问卷调查。3结果　被调查护士长的艾森克个性问卷中神经质维度 (N)得分为 (9.6 7± 4.6 3)分 ,显著低于常模(t=5 .114,P<0 .0 1) ;内向 -外向 (E)得分为 (10 .18± 3.86 )分 ,显著高于常模 (t=3.6 10 ,P<0 .0 1) ;精神质维度 (P)得分为 (4.15± 2 .97)分 ,显著低于常模 (t=7.6 95 ,P<0 .0 5 ) ;L 得分为 (13.94± 3.6 0 )分 ,显著高于常模 (t=5 .0 89,P<0 .0 1)。护士长行为类型问卷总分为 (2 8.46± 5 .97)分 ,其中 A型行为倾向者占 5 5 .93% .4结论　本组护士长有较强的外倾人格特征。     

妊娠晚期血清总唾液酸测定

目的 :测定孕妇妊娠晚期血清总唾液酸 (TSA)含量 ,探讨血清唾液酸水平在妊娠晚期的变化。方法 :酶法测定 89例妊娠 33～ 4 0周孕妇 (孕妇组 )及 4 6例健康年轻未孕女性 (对照组 )血清总唾液酸含量。结果 :4 6例对照组TSA含量为 :(5 94 .8± 6 2 .4 )mg /L ,89例孕妇组TSA含量为 :(71 0 .6±71 .8)mg/L。两组比较t=9.2 ,P <0 .0 0 1。结论 :妊娠晚期孕妇血清唾液酸水平显著增高     

孕妇血清钙、磷测定

目的　检测孕妇血清Ca2 、P3 浓度 ,了解孕妇血钙的变化。方法　检测 5 6例孕妇血清Ca2 、P3 的浓度 ,同龄非孕妇 42例做对照。结果　孕妇组血清Ca2 (2 15 6± 0 182 )明显低于对照组Ca2 (2 2 76±0 12 6 ) ,t=3 85 ,P <0 0 1,差异非常显著 ;孕妇血清游离Ca2 (1 143± 0 0 96 )也明显低于对照组 (1 2 10±0 136 )t=2 72 ,P <0 0 1,差异非常显著 ;血清磷两组无明显差异 (t=1 2 0 ,P >0 0 5 )。讨论　了解孕妇血钙的代谢水平 ,并在妊娠期补充钙剂 ,有利于优生     

术前腹腔动脉插管化疗对中晚期胃癌细胞凋亡和增殖的影响

目的　探讨术前腹腔动脉插管化疗对中晚期胃癌细胞凋亡和增殖的影响。　方法　采用切口末端标记法 (TUNEL)、增殖细胞核抗原 (PCNA)和凋亡抑制基因蛋白 (Bcl 2 )免疫组织化学检测技术 ,观察比较术前腹腔动脉插管化疗组 (治疗组 )和术前未化疗组 (对照组 )中晚期胃癌细胞的凋亡指数、增殖指数和Bcl 2蛋白表达强度的差异。　结果　治疗组与对照组凋亡指数分别为 5 .71± 0 .12和 2 .37± 0 .15(t=97.39,P <0 .0 1) ,增殖指数分别为 4 1.5 0± 0 .14和 5 8.11± 0 .13(t =4 8.8,P <0 .0 1) ,Bcl 2分值为1.5 0± 0 .6 4和 2 .38± 0 .4 9(t=4 2 .8,P <0 .0 1)。凋亡指数与Bcl 2分值呈显著负相关 (rs=- 0 .74 3,P <0 .0 1) ,凋亡指数与增殖指数呈中度正相关 (rs=0 .4 0 0 ,P <0 .0 5 )。治疗组治愈性切除率、3年生存率明显高于对照组 (χ2 =8.5 8,P <0 .0 1;χ2 =4 .0 9,P <0 .0 5 )。　结论　术前腹腔动脉插管化疗可诱导中晚期胃癌细胞凋亡 ,降低肿瘤细胞的增殖活力 ,提高治愈性切除率和患者生存率。诱导胃癌细胞凋亡可能与化疗药物降低Bcl 2基因蛋白的表达有关     

环球航行船员人格特征及心理健康状况调查

①目的　了解参加环球航行船员的人格特征和心理健康状况 ,为心理干预提供依据。②方法　对2 93例出海船员进行明尼苏达多项人格问卷 (MMPI)和症状自评量表 (SCL 90 )测试 ,并与中国常模进行比较。③结果　船员MMPI中的Q、L、F、K等 4个效度量表和 1 0个临床量表的得分值与中国常模比较 ,差异均有显著性(t=3.0 5～ 36 .4 6 ,P <0 .0 0 1 )。船员躯体化、忧郁两项因子分与中国常模比较 ,差异有显著性 (t =4 .2 8、7.81 ,P <0 .0 5 )。④结论　环球航行船员的人格特征和心理健康水平整体较佳 ,但部分船员需要进行心理干预     

未婚先孕女性心理健康状况调查

1　资料和方法1999年 6月～ 2 0 0 0年 6月来我院妇产科检查 ,经检验科检查确诊为怀孕 ,经医师仔细询问均为未婚 ,怀孕时间 8周以内 ,且愿意接受量表调查者。填表者 40例 ,有效 36例 ;年龄 18～ 2 4岁 ,平均 (2 0 12± 1 34)岁 ;大学 2例 ,高中 6例 ,初中及以下 2 8例。统计方法采用ｔ检验。2　结果2 1　未婚先孕者ＳＣＬ - 90评分结果与常模比较 ,除偏执外 ,各因子分差异有显著性 (Ｐ <0 0 5 )及非常显著性 (Ｐ <0 0 1)。见表 1。表 1　未婚先孕女性与国内常模ＳＣＬ - 90比较 ( Ｘ±Ｓ)项目 未婚先孕(ｎ =36 )常模(ｎ =13 88) Ｐ总　…     

经尿道气化电切术治疗高龄高危前列腺增生症

目的　探讨经尿道气化电切术治疗高龄高危前列腺增生症 (BPH)的方法和疗效。方法　采用经尿道前列腺气化电切术治疗高龄高危BPH患者 87例。结果　全部病例均顺利耐受手术。前列腺重 2 2～ 12 8g ,平均 35 .7g ,切除腺体组织重量 9～ 6 1g ,平均 32g。手术时间 2 1～ 87min ,平均 4 9min。国际前列腺症状评分 (IPSS)由术前的 2 6 .8± 4 .2分降至术后 9.3± 3.7分 (t=- 2 7.5 5 ,P <0 .0 1) ;生活质量评分 (QOL)由术前的 5 .9± 0 .8分降至术后 2 .1± 0 .5分 (t=- 2 9.93,P <0 .0 1) ;最大尿流率 (MFR)由术前的 5 .6± 3.7ml s升至术后 18.4± 4 .1ml s(t=14 .95 ,P <0 .0 1) ,平均尿流率 (AFR)由术前的 2 .8± 0 .9ml s升至术后 10 .1± 2 .1ml s(t=17.6 7,P <0 .0 1) ;剩余尿量 (RU)由术前的 183± 6 9.3ml降至术后 35 .2± 16 .3ml(t=- 9.6 4,P <0 .0 1)。随访 3～ 2 4月 ,平均 19月 ,排尿通畅。结论　经尿道前列腺气化电切术是治疗高龄高危BPH患者安全有效的方法     

性传播疾病高危人群自我接纳程度分析

①目的　了解性传播疾病高危人群的自我评价及自我接纳程度。②方法　对 1 2 7名非强迫状态下的性传播疾病高危人群个体进行自我接纳问卷 (SAQ问卷 )调查 ,并与大学新生测定结果 (常模 )进行比较。③结果性传播疾病高危人群SAQ问卷总分及自我评价因子分 (SE)均高于大学新生组 ,差异有显著性 (t =3.72、1 1 .4 5 ,P <0 .0 1 ) ;而自我接纳因子分 (SA)明显低于大学新生组 ,差异也有显著性 (t=6 .32 ,P <0 .0 1 )。④结论　性传播疾病高危人群的自我接纳高于大学新生     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.