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[目的]为大鼠压疮模型提供可靠的造模装置及有效的造模方法。[方法]制作大鼠压疮模型造模装置,并使用该装置对211只大鼠进行缺血2.0 h、再灌注0.5 h 造模,观察不同造模时间大鼠受压位置的皮肤颜色、形态及大鼠行为学变化。[结果]1 d 可制备出Ⅰ期压疮模型的大鼠186只,成功率达88.15%;2 d 共制备Ⅱ期压疮模型208只,成功率达98.58%。[结论]该装置可有效制备大鼠压疮模型,并且简单、方便、廉价,对压疮创面以外区域无额外损伤,从而为大鼠压疮实验的机制及防治等相关研究提供可靠的模型。 相似文献
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目的:观察面肌痉挛患者经显微血管减压术后行针刺预处理对迟发性面神经麻痹的发病率、发病持续时间、面部神经损伤情况的影响。方法:将行显微血管减压术的356例面肌痉挛患者,随机分成两组。对照组给予激素、血管扩张剂、神经营养药物综合治疗。针药防治组在对照组基础上给予针刺处理,持续4周。随访时间6~12个月。分析比较两组患者迟发性面神经麻痹发生率、面神经损伤功能分级。结果:对照组出现迟发性面神经麻痹22例,发病率12.36%,其中Ⅱ级5例,Ⅲ级10例,Ⅳ级7例,术后发病持续时间(61.82±12.99) d。针药防治组出现迟发性面神经麻痹9例,发病率5.06%,其中Ⅱ级6例,Ⅲ级2例,Ⅳ级1例,术后发病持续时间(45.67±11.98) d。两组患者发病率、面神经损伤功能分级、迟发性面神经麻痹持续时间比较,差异均具有统计学意义(P0.05)。结论:针刺预处理可以减少面肌痉挛患者显微血管减压术后迟发性面神经麻痹的发病率,并可将病程缩短、有效减轻面部神经损伤情况。 相似文献
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祖国医学认为,单纯性肥胖症是在多种因素的作用下,机体脏腑气血阴阳失调,导致水湿、痰浊、膏脂等盛于体内。病因与先天禀赋有关,与饮食不节,久卧久坐,年老体衰,七情内伤亦有关。病机多为本虚标实,病位主要在脾、胃、肾。研究表明,通过刺激耳部穴位,可以调节消化功能,刺激迷走神经进而影响胰岛素分泌,抑制饥饿感,控制能量的摄入,改善肥胖症状。 相似文献
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Objective
To observe the clinical efficacy of fire-needle therapy in treating deglutition disorders due to pseudobulbar palsy in the remission stage of stroke.Methods
Sixty-two eligible subjects were divided into a fire-needle group and a rehabilitation group by a simple randomization method at a ratio of 1:1. The two groups received same basic intervention; in addition, the fire-needle group received fire-needle treatment, while the rehabilitation group received rehabilitation training. The two groups of subjects all received a 3-week treatment and were evaluated by the dysphagia severity rating scale (DSRS), modified Mann assessment of swallow ability (MMASA) and Kubota Toshio swallow test (KTST) before and after the intervention. The complications and adverse events occurred during the trial were recorded. The data were statistically analyzed.Results
At the third week, the DSRS, MMASA and KTST scores changed significantly compared with the baseline in both groups (P<0.05), and the changes in the fire-needle group were more significant than those in the rehabilitation group (P<0.05). The between-group comparison at the third week showed that the therapeutic efficacy in the fireneedle group was superior to that in the rehabilitation group (P<0.05).Conclusion
Fire-needle therapy can obviously change the DSRS, MMASA and KTST scores in pseudobulbar palsy in the remission stage of stroke, and significantly enhance the therapeutic efficacy of the treatment of deglutition disorders in this stage.6.
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流行性腮腺炎并发急性胰腺炎17例临床分析 总被引:1,自引:1,他引:0
目的提高流行性腮腺炎并发急性胰腺炎的早期诊断和治疗。方法对17例流行性腮腺炎并发急性胰腺炎的临床表现、辅助检查、治疗进行回顾分析。结果17例流行性腮腺炎并发急性胰腺炎患儿,以发热、呕吐、腹痛、腮腺肿大、血尿淀粉酶明显升高及胰腺CT异常表现为主,血清淀粉酶大于或等于正常值的3倍以上,胰腺CT异常率为53.1%,均为轻型急性胰腺炎,15例全部治愈,2例好转出院。结论流行性腮腺炎如出现呕吐、腹痛、发热、应尽早行血尿淀粉酶、胰腺CT检查,以早期诊断并发急性胰腺炎,并及时进行综合治疗。 相似文献
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