老年冠心病患者血液流变学对比观察

本文就164例老年冠心病(CHD)患者血液流变学变化与100名健康老年人比较,发现老年CHD患者血液流变学改变是明显的,尤以全血低切粘度(?)20S~(-1)最为显著(t检验,P<0.002).从临床分型看,CHD越严重,血液流变学改变越明显.但隐匿型CHD患者与健康老年人的血液流变学指标比较,无明显差异.提示血液流变学检查不适用于CHD的早期诊断,但可以判断CHD的严重程度及其预后,对指导治疗及疗效观察有一定的参考价值.     

A Simple Rheological Method for the in Vitro Assessment of Mucin-Polymer Bioadhesive Bond Strength

A simple viscometric method was used to quantify mucin-polymer bioadhesive bond strength. Viscosities of 15% (w/v) porcine gastric mucin dispersions in 0.1 N HC1 (pH 1) or 0.1 N acetate buffer (pH 5.5) were measured with a Brookfield viscometer in the absence (_m) or presence (_t) of selected neutral, anionic, and cationic polymers (0.1–2.5%, w/v). Viscosity components of bioadhesion (1%) were calculated from the equation, _t = _m + _p + _b, where _p is the viscosity of corresponding pure polymer solution as measured by an Ostwald viscometer. The forces of bioadhesion (F) were calculated from the equation, F = _b, where is the rate of shear/sec. _b's and F's for polyelectrolytes, e.g., polyacrylic acid, cationic gelatin, and chitosan were always higher in acetate buffer than in HC1. Validity of the technique and the effect of ionic charge, polymer conformation, and rate of shear on _b and F are discussed, as is a comparison of this method to other methods for evaluating bioadhesive materials.     

糖尿病患者血液流变学分析

目的　对糖尿病的血液流变学测试结果进行分析 ,揭示糖尿病患者慢性病变的发病机理。方法　对186例糖尿病患者组和 12 0例健康对照组的血液流变学检查结果进行分析研究。结果　糖尿病患者呈高粘滞血症(P <0 .0 1)。红细胞聚集和刚性指数有不同程度升高 (P <0 .0 5 ) ,而红细胞变形和电泳指数有明显降低 (P <0 .0 5 )。结论　血液粘度升高是糖尿病患者微血管病变进而导致多种合并症的重要原因。     

血液血细胞比容血沉纤维蛋白原同血流变学相关指标检测的分析

本文通过临床常用的HCT、FIb、ESR与血流变中全血粘度、血浆粘度和红细胞聚集性之间相关性的实验对照观察、理论分析 ,认为血细胞比容 ,血沉和纤维蛋白原检测反映血液浓度、粘度、聚集、凝血状态是有一定相关价值。因此 ,再配合临床必要的生化实验 ,如血糖、血脂等检测采用微机对检测数据处理对心脑血管疾病的预测、疗效观察具有更实用的价值     

新生儿脐血血液流变学观察

目的 :观察新生儿脐血的血液粘度、血浆粘度、红细胞压积、血沉、红细胞电泳情况。方法 :新生儿分娩断脐后立即抽取脐血 4ml+肝素抗凝 ,并立即送检 ,采用北京普利生 L BY- N6 A自清洗旋转式粘度计检验。结果 :母体为正常生理妊娠的新生儿组 :全血低切粘度 8.91± 6 .79m pa· s,全血高切粘度 5 .6 6± 2 .0 mpa· s,血浆粘度 1 .46± 0 .2 4m pa· s,红细胞压积 5 0 .1±1 8.4% ,血沉 2 .1 4± 1 .36 mm/ h,红细胞电泳 1 5 .82± 3.79s;母体为妊高征的新生儿组 :全血低切粘度 1 1 .96± 7.38m pa· s,全血高切粘度 6 .48± 1 .5 7mpa· s,血浆粘度 2 .5 3± 1 6 .4mpa· s,红细胞压积 31 .47± 0 .35 % ,血沉 1 .6 8± 1 .43mm/ h,红细胞电泳1 5 .6 8± 3.43s;正常妇女组 :全血低切粘度 2 2 .33± 6 .88mpa· s,全血高切粘度 4.5 0± 0 .5 4mpa· s,血浆粘度 1 .73± 0 .0 9mpa· s,红细胞压积 41 .0 9± 2 .6 0 % ,血沉 1 7.0 9± 6 .35 mm/ h,红细胞电泳 2 1 .0 4± 1 .44 s。结论 :孕期母体血液流变学变化对新生儿影响较小     

小儿手术前后血液流变学检测的临床意义分析

目的 了解小儿手术前后血液流变特性的变化规律,探讨手术创作对小儿全身的影响,指导小儿围手术期处理。方法 使用自身前后对照,并取小儿健康对照及同期成年患者对照,全部病例无影响血液流变特性疾病,未服用影响血液流变特性药物,体温正常,分别于术晨,术后即刻,术后１天抽血抗凝送检测定全血粘度（ＷＢＶ）,血浆粘度（ＰＶ）,纤维蛋白原（Ｔｉｄｇ）、血沉（ＥＳＲ）、红细胞压积（ＨＣＴ）,红细胞刚性指数（ＩＲ）及聚     

Nebulization of Fluids of Different Physicochemical Properties with Air-Jet and Ultrasonic Nebulizers

Purpose. Empirical formulae relate the mean size of primary droplets from jet and ultrasonic nebulizers to a fluid's physicochemical properties. Although the size selective filtering effects of baffling and evaporation may modify the secondary aerosol produced, this research sought to evaluate whether viscosity and surface tension of nebulized fluids influenced the aerosol's size and output characteristics. Methods. Fluid systems of different surface tension and viscosity (glycerol and propylene glycol solutions [10–50% (v/v)] and a range of silicone fluids [200/0.65 cs– l00cs]) were nebulized in three jet and two ultrasonic nebulizers. Secondary aerosol characteristics were measured with a Malvern 2600C laser diffraction sizer and the nebulization times, residual volumes and percentage outputs were determined. Results. While the droplet size appeared to be inversely proportional to viscosity for jet nebulizers, it was directly proportional to viscosity for ultrasonic nebulizers. Although fluid systems with lower surface tensions generally produced slightly smaller MMDs, the relationship between surface tension and droplet size was complex. The more viscous fluids required longer nebulization times and were associated with increased residual amounts (lower outputs). The ultrasonic nebulizers did not effectively, and were on occasion unable to, nebulize the more viscous fluids. Conclusions. It follows that there are cut-off values for viscosity and/or surface tension above or below which ultrasonic devices fail to operate. Moreover, jet nebulizers generated an aerosol with an optimum respirable output from median-viscosity fluids.     

矽肺患者血液流病变与血清免疫球蛋白关系的临床研究

为了探索矽肺患者免疫球蛋白的变化与血液流变学的关系,我们测定了本院门诊及住院的８３例不同期别矽肺病人的血清免疫球蛋白和血液流变学有关指标。结果显示：晚期（Ⅱ、Ⅲ期）和进展期矽肺患者的血液高粘滞状态不仅与红细胞比积及红细胞的粘弹特性有关,而且与血清免疫球蛋白、尤其是ＩｇＧ和ＩｇＡ的含量增加有关,而与纤维蛋白原未显示相关。     

中国健康中青年女性全血比粘度参考值与海拔高度的关系

目的：为制定中国健康中青年女性全血比粘度参考值的统一标准提供科学依据。方法：收集了中国各地用毛细管法测定的健康中青年女性全血比粘度参考值,并对其与海拔高度的关系进行了研究。结果：发现随着海拔高度的逐渐增大,健康中青年女性全血比粘度参考值也在逐渐增大,相关性很显著。用一元回归分析的方法推导出一个回归方程。结论：如果知道了中国某地的海拔高度,就可以用回归方程估算这个地区的健康中青年女性全血比粘度参考值。     

高压下滴流床反应器动持液量的测定

在常压－２．０ＭＰａ的系统压力下测定了滴流床中气－液两相并流下流动的动持液量,了气－液流率,液相粘度,填料大小,压力以及床层高度对动持液量的影响。实验结果表明增中液体流率动持流量增加,气体流率增加时,结果相反粘度的增加对动持液量的影响不大,动持液量随填料空隙率的增大而变小。