3种机械清洁方法对树脂外源性着色的清洁效果

目的评估3种机械清洁方法即电动牙刷配合清洁膏、牙膏或自来水刷洗对热固化型基托树脂外源性着色的清洁效果。方法制作60块热固化基托树脂试件,随机分成4组,用电子比色仪测色后,分别浸泡入蒸馏水(对照组)、绿茶、漱口水、黄连水中4周。再将后3组实验组各分成3组,分别以自来水、牙膏或清洁膏作为刷洗液,用电动牙刷刷洗10 min后再次测色。计算各组试件刷洗后与浸泡前的色差。方差分析法比较3种机械清洁方法对试件外源性着色的清除能力。结果刷洗方法及浸泡液种类均影响试件的颜色改变,各实验组试件表面颜色的改变与对照组相比均有显著性差异(P﹤0.05)。绿茶组中清洁膏与牙膏之间、牙膏与空刷之间无统计学意义(P﹥0.05),清洁膏与空刷之间有统计学差异(P﹤0.05)。漱口水与黄连水中3种清洁方法两两间均有显著性差异(P﹤0.05),且以清洁膏组试件表面色差最小,牙膏次之。结论 3种机械清洁方法清除热固化型基托树脂表面着色的效果有差异,以清洁膏效果最好。     

The mitigation effects of exogenous melatonin on salinity-induced stress in Malus hupehensis

Abstract:  As an indoleamine molecule, melatonin mediates many physiological processes in plants. We investigated its role in regulating growth, ion homeostasis, and the response to oxidative stress in Malus hupehensis Rehd. under high‐salinity conditions. Stressed plants had reduced growth and a marked decline in their net photosynthetic rates and chlorophyll contents. However, pretreatment with 0.1 μm melatonin significantly alleviated this growth inhibition and enabled plants to maintain an improved photosynthetic capacity. The addition of melatonin also lessened the amount of oxidative damage brought on by salinity, perhaps by directly scavenging H₂O₂ or enhancing the activities of antioxidative enzymes such as ascorbate peroxidase, catalase, and peroxidase. We also investigated whether melatonin might control the expression of ion‐channel genes under salinity. Here, MdNHX1 and MdAKT1 were greatly up‐regulated in the leaves, which possibly contributed to the maintenance of ion homeostasis and, thus, improved salinity resistance in plants exposed to exogenous melatonin.     

中药外源性污染物检测技术的现代研究

中药外源性污染物残留现已成为引起中药不良反应的重要原因之一,按照其来源不同主要包括农/兽药残留、重金属污染、真菌毒素残留、病原微生物污染及其他有机污染物残留。对中药的主要外源性污染物的检查对象及检测方法的现代研究进行综述,为补充、完善、提升中药质量安全体系提供参考和依据。     

In vitro activities of inulin fermentation products to HCT-116 cells enhanced by the cooperation between exogenous strains and adult faecal microbiota

Inulin was fermented by adult faecal microbiota and 10 exogenous strains for 24 or 48?h. The contents of acetate, propionate, butyrate and lactate were quantified in the fermented products, and the growth-inhibitory and apoptosis-inducing effects on a human colon cell line (HCT-116 cells) were assessed. Most of these strains increased contents of acetate, propionate and butyrate, and promoted lactate conversion. Correlation analysis suggested that butyrate and lactate in the fermentation products were positively and negatively correlated with the measured inhibition ratios (p?via inducing DNA fragmentation and increasing total apoptotic populations in the treated cells. Moreover, the fermentation products with higher growth-inhibitory activities demonstrated the increased apoptosis-inducing properties. In conclusion, these strains could cooperate with adult faecal microbiota to confer inulin fermentation products with higher anti-colon cancer activity.     

外源性物质对猪苓菌丝体生长及多糖含量的影响

目的 为探讨不同外源性物质对猪苓菌丝生长发育的影响,系统研究了不同浓度外源性物质处理后猪苓菌丝生长速度及其多糖含量,以期筛选出猪苓菌丝的最佳生长条件,为其规模化人工培养提供参考。方法 采用平皿培养真菌的方法,将猪苓菌丝放在含有不同外源性物质的培养基上进行了培养,以菌落直径来判断菌丝的生长速度,苯酚-硫酸法测定猪苓菌丝的多糖含量。结果 高浓度环磷腺苷酸,6-苄氨基嘌呤（6-BA）,赤霉素（GA）,2,4-二氯苯氧乙酸（2,4-D）,维生素（V）B₁,VB₃,VB₆,VB₉,VB₁₂处理组均促进了猪苓菌丝生长,而吲哚乙酸（IAA）,VC,VB₂处理组均抑制了猪苓菌丝生长;高浓度环磷腺苷酸,6-BA,GA,2,4-D,VB₁,VB₃,VB₆,VB₉,VB₁₂处理组均提高了猪苓菌丝多糖含量,而IAA,VB₂处理组均降低了其多糖含量。高浓度VC处理组对猪苓菌丝生长抑制最为明显,但能显著增加猪苓菌丝多糖含量;环磷腺苷酸浓度为2 mmol·L^-1,6-BA,GA,2,4-D,VB₁,VB₂,VB₃,VB₉,VB₁₂质量浓度分别为6,15,2,4,2,4,6,10 mg·L^-1时,均有利于猪苓菌丝生长和多糖含量的累积。结论 通过在培养基中添加外源物质可以调控猪苓菌丝的生长发育,改变猪苓菌丝生长速度和多糖含量的累积。     

Exogenous ochronosis in ethnic Chinese Asians: a clinicopathological study,diagnosis and treatment

Background Exogenous ochronosis is believed to be an uncommon complication of treatment with hydroquinone‐ containing skin‐lightning agents. It is widely believed that the condition is found almost exclusively in dark‐skinned individuals and uncommon in other skin‐types. Aims To show that exogenous ochronosis may be present in ethnic Chinese Asians. Materials & Methods Facial skin biopsies were obtained from suspicious lesions in ethnic Chinese patients presenting at a private dermatology clinic. Clinical photographs, ultraviolet (UV) photographs and digital dermatoscopic pictures were also obtained. Results 15 patients of ethnic Chinese origin had histologically‐confirmed exogenous ochronosis. Discussion The difficulties in differentiating exogenous ochronosis from melasma are discussed and there is a likelihood of under‐reporting as the clinical presentation of the condition may be misleading. Conclusion Exogenous ochronosis may exist amongst ethnic Chinese patients with fairer skin‐types, contrary to the commonly‐accepted perception that it is more prevalent in darker skin‐types.     

《伤寒论》在治疗病毒性心肌炎中的应用探析

病毒性心肌炎是指人体感染了嗜心性病毒,引起的心肌非特异间质性炎症。仲景以六经辨证、分经审证,在《伤寒论》里详细论述了病毒性心肌炎在六经传变中的症状表现。     

五苓散证发微

五苓散证是《伤寒论》重点汤方证,又是临床常用方。文章就《伤寒论》五苓散证的相关问题进行了简要论述,并吸收历代《伤寒论》注家的观点,并结合当代的临床实际经验及实验研究,来验证、阐明过去认为难以理解或有歧义的《伤寒论》中的某些证候,使古老的汤方证论治在现代临床重现生机。     

口咽部微生态环境与外感病中医证型的相关性研究

中医证型的客观化研究是中医现代化研究的重要方面。近年来研究表明,微生态学与中医学的某些理论在认识方法上存在统一性,运用微生态学的原理和方法研究中医证型的客观化指标,不但有助于中西医结合的发展,同时也为中医药学的现代化研究提供新的思路和方法。     

外生性十二指肠平滑肌肉瘤的影像诊断(附6例报告)

目的　评价各种影像检查方法对外生性十二指肠平滑肌肉瘤的诊断价值。方法　外生性十二指肠平滑肌肉瘤 6例 ,均行消化道钡餐造影 ,B超检查 ,CT检查和 /或MR检查和血管造影检查。结果　所有病例均经手术病理证实为外生性平滑肌肉瘤。上消化道造影表现为外压性改变 ,2例可见肠道外不规则钡斑 ,B超显示上腹实性肿块 ,CT、MR显示为实性肿块 ,2例可见肿块与十二指肠相连 ,血管造影表现为多血供肿瘤 ,由胃十二指肠动脉和肠系膜上动脉的分支右、中结肠动脉供血。结论　外生性十二指肠平滑肌肉瘤的诊断应在消化道作钡餐的基础上联合应用CT和 /或MR及血管造影检查。