HPLC法测定小柴胡颗粒剂中黄芩苷的含量

目的 :建立小柴胡颗粒剂中黄芩苷的含量测定方法。方法 :采用反相高效液相色谱法。色谱柱 :Inertsil ODS- 3(5 μm,4 .6× 2 5 0 mm)柱 ;流动相 :甲醇 -水 -磷酸 (45∶ 5 5∶ 0 .2 ) ;检测波长 :315 nm。结果 :黄芩苷在 0 .2 4 2 9～ 1.2 14 4 μg/ml范围内呈现良好的线性关系 (r=0 .9999) ,回收率 10 0 .0 % ,RSD=0 .96 %。结论 :本法可用于测定小柴胡颗粒剂中黄芩苷的含量。     

益母草中阿魏酸的色谱鉴别

目的：鉴别益母草中是否含阿魏酸,方法：采用薄层色谱法和高效液相色谱法鉴别不同提取溶煤制备的样品,结果：从益母草中能检出阿魏酸。结论：益母草中可能含游离的阿魏酸,以5％Na2CO3溶液替代药典中的甲醇提取,方法简化,稳定性高,重现性好。     

Successful Treatment of Erdheim-Chester Disease With Coronary Artery Involvement

Erdheim-Chester disease (ECD) is a rare non-Langerhans histiocytosis and inflammatory myeloid neoplasm with poor prognosis. Symmetric long bone osteosclerosis occurs in nearly all patients, but other organs are often involved. Coronary artery involvement is rare, but was encountered in a patient who experienced angina. Radiologic presentation and histologic findings were consistent with diagnosis of ECD. A soft-tissue mass was found surrounding the right atrium, ascending aorta, and all branches of coronary artery. Interferon-alfa treatment was successful. In conclusion, we recommend coronary artery computed tomography angiography for cardiovascular evaluation of ECD and interferon-alfa to treat ECD.     

胡思荣辨治咳嗽经验

胡思荣辨治咳嗽,在继承了先贤整体论及辨证论治等核心思想的基础上,务实地补充了自己的新解。临证中擅长运用温病学理论,倡导和调气机的指导思想,从三焦气化功能角度辨证,采用宣降同用,化润并举,上下分消等法论治咳嗽,引入因时参辨,灵活施药,发挥中医"整体观念""辨证论治"之优势,临证思辨,效如桴鼓。     

新疆规模羊场萨福克与湖羊杂交应用试验

为建立适应新疆规模化羊场的杂交生产体系,提高种羊利用率及当地绵羊的生产性能,以萨福克羊为父本、湖羊为母本,在规模羊场开展杂交应用试验。以出生日龄相近的萨湖F1为试验组,湖羊羔羊为对照组,测定初生重、2月龄重、4月龄重、6月龄体重、6月龄体尺等生长指标及宰前活重、胴体重、净肉重、屠宰率和净肉率等屠宰性能指标。结果表明,萨湖F1羔羊的2月龄重、4月龄重、6月龄体重及日增重显著高于湖羊F1羔羊(P0.05),6月龄萨湖F1羔羊平均宰前活重、胴体重、净肉重、屠宰率及净肉率显著高于湖羊F1羔羊(P0.05)。利用萨福克杂交改良规模羊场湖羊,可以显著提高羔羊的生长发育,杂种优势显著。     

覆盆子活性成分山奈酚的含量测定

目的：建立覆盆子改善肾阳虚型痴呆活性成分山奈酚的含量测定方法。方法：采用高效液相色谱法。色谱柱为Diamon－sil C18（250mm ×4.6mm,5μm）,流动相：乙腈－0.1％磷酸水（30∶70）,流速1 mL／min,柱温30℃,检测波长266nm,进样量20μL。结果：山奈酚质量在0.0782～5.000μg范围内与峰面积呈良好的线性关系（r＝0.9999）,平均加样回收率为99.50％, RSD＝2.1％。结论：试验方法简便、快速、实验结果准确可靠,该方法可作为覆盆子有效成分山奈酚含量测定的方法。     

湖南白族少年儿童体型特征

目的探讨湖南白族少年儿童体型发育特征及其规律。方法采用Heath-Carter体型法对1525例(男性748例,女性777例)湖南白族少年儿童的体型进行评价。结果男性中因子值大于女性,内因子值小于女性;男性体型以中胚层、外胚层为主,女性体型以中间型、外胚层为主;随着年龄增长,男性由均衡的中胚层体型、偏外胚层的中胚层体型、中胚层-外胚层均衡体型、偏中胚层的外胚层体型发展为中胚层-外胚层均衡体型。女性由中间型、均衡的外胚层体型、中间型、内胚层-中胚层均衡体型发展为偏中胚层的内胚层体型。结论白族少年儿童男女性的体型发育存在着差异,男性身体线性程度相对较高,肌肉发达;女性脂肪含量较多、线性度较差。与蒙古族等群体比较,白族学生脂肪含量较少,身材矮小,肌肉不发达。     

Simple Analysis of the Computed Tomography Features of Gastric Schwannoma

ObjectiveThe objective of this study was to assess the computed tomography (CT) findings of gastric schwannoma (GS) and identify the difference between large (> 5 cm) and small (≤ 5 cm) GS.Materials and MethodsCT findings of 38 pathologically proven cases of GSs were retrospectively reviewed. The CT evaluation of GS included categorical variables (location, contour, growth pattern, enhancement pattern, necrosis, ulceration, calcification, and lymph nodes) and continuous variables (size, CT value of 3 phases, and enhancement degree). The lesion was divided into 2 groups (large [> 5 cm] and small [≤ 5 cm] GS) according to the tumor size. The Fisher exact test was used for categorical variables and the Student t or Mann-Whitney U test for continuous variables.ResultsOf the 38 patients, there were 32 women and 6 men. The median age was 54.5 years (range 39–79). Most of patients (65.8%, [25 of 38]) had nonspecific gastrointestinal symptoms such as abdominal or gastric pain, fullness and discomfort, bleeding, and melena. The tumors were mainly located in the stomach body (71.1% [27 of 38]), and the mean diameter was 3.7 cm (range 1.5 cm-10.3 cm), of which included large (> 5 cm) (n = 8) and small (≤ 5 cm) (n = 30). All of the GSs were benign, 9 of whom had palpable perigastric lymph nodes, which confirmed by pathology for the reactive inflammatory hyperplasia. Growth pattern, pattern of enhancement, necrosis, calcification, surface ulceration, and lymph node in the CT images were found to be significant variables for differentiating large (> 5 cm) and small (≤ 5 cm) GS (P < .05).ConclusionGSs were predominantly located at the gastric body and occurred most frequently in women between the ages of 40–70 years, and showed gradual enhancement after contrast enhancement. Palpable perigastric lymph nodes could not be considered as malignant factor of GS. There 7 computed CT criteria are significant difference between large (> 5 cm) and small (≤ 5 cm) GS.     

《神农本草经》中与神志相关的药物归类分析——胡随瑜教授《神农本草经》讲记(四)

中医学言"情志"多,论"神志"少.后者不仅包含七情,还涉及神、魂、魄、意、志等.本讲从神与五志入手,对《神农本草经》(以下简称为《本经》)中与神志相关的药物进行归类分析,以了解古圣如何认知及应用本草,改善或健全脑功能,校正失衡的心理与情志,达到维持神志健康的目的.     

《神农本草经》“下气”相关药物归类及浅析——胡随瑜教授《神农本草经》讲记(六)

《本经》中与“气”相关的药物记述术语有:“下气”、“咳逆上气”、“邪气”、“结气”、“益气”等等.一般非指普通概念的理气药.如何理解此类药物的属性与作用特征?本讲选择“下气”,“咳逆上气”两类药物进行归类分析,以期为气机失调,尤其是气的逆顺论治,拓宽药物选择的思路与方法.