准分子激光角膜表面切削术治疗近视的疗效分析

应用美国ＣＨＩＲＯＮ公司ｋｅｒａｃｏｒ１１７型准分子激光治疗仪对６８例１３０眼近视患者行ＰＲＫ治疗。术前屈光度（等值球镜）为－２．００—－９．７５Ｄ（ｘ±ｓ：－５．１１±１．８１Ｄ）散光度０—－４．０Ｄ。结果：术后３—６个月残留屈光度为＋０．０８±０．２９Ｄ，裸眼视力≥０．８者占９４．２％，≥１．０者占９０．４％。术前屈光度－２Ｄ—－６Ｄ患眼，术后３—６个月裸眼视力≥０．８者占９５．２％，≥１．０者占９４．２％；术前屈光度－６．２５Ｄ—－９．７５Ｄ者，术后３—６个月裸眼视力≥０．８者占９１．７％，≥１．０占６５．４％。实际矫正度数在预测矫正度±０．５Ｄ范围内者占８４．６％，０．８％的术眼有２级以下的角膜上皮下雾状混浊，１．５％术眼角膜有丝状物，１．５％术眼用药后一过性眼压升高，最佳矫正视力下降１行者占５．２％。结论：ＰＲＫ治疗中低度近视是一种安全，有效的手术方法。其稳定性好，预测性强，值得临床应用。但术后应注意护理及随访。     

准分子激光屈光性角膜切削术与激光原位角膜磨镶术治疗中低度近视的对比

目的对准分子激光屈光性角膜切削术（ｐｈｏｔｏｒｅｆｒａｃｔｉｖｅｋｅｒａｔｅｃｔｏｍｙ，ＰＲＫ）和准分子激光原位角膜磨镶术（ｌａｓｅｒａｓｓｉｓｔｅｄｉｎｓｉｔｕｋｅｒａｔｏｍｉｌｌｅｕｓｉｓ，ＬＡＳＩＫ）治疗中、低度近视的疗效进行前瞻性对比研究。材料和方法术前屈光度为－１．２５～－６．００Ｄ的近视５６９只眼，其中１３７只眼接受ＬＡＳＩＫ手术，４３２只眼接受ＰＲＫ手术，随访６－１６个月（平均８．９±２．６个月）。在术后１周、１个月、３个月、６个月和１２个月复查。结果ＬＡＳＩＫ组术后屈光状态较ＰＲＫ稳定，回退幅度较ＰＲＫ小，术后６个月时，ＬＡＳＩＫ组和ＰＲＫ组分别有９４％和８７％屈光度在±１．００Ｄ内（ｐ＜０．０５），分别有８４％和７１％屈光度在±０．５０Ｄ以内（ｐ＜０．０１）。ＬＡＳＩＫ组术后视力恢复较ＰＲＫ快，术后１周的平均裸眼视力超过１．０，术后６个月时，ＬＡＳＩＫ和ＰＲＫ组中裸眼视力０．５或以上者分别占１００％和９４％（ｐ＜０．０１），裸眼视力１．０以上者分别占８６％和７２％（ｐ＜０．０１）。结论ＬＡＳＩＫ不仅适合治疗高度近视，也适合治疗中、低度近视。对于中、低度近视，ＬＡＳＩＫ的疗效优于ＰＲＫ。     

PRK治疗RK后残余近视散光二年疗效分析

目的： 评价准分子激光屈光性角膜切削术治疗放射状角膜切开术后残余近视散光的预测性、稳定性和安全性。方法： 对５２ 眼 Ｒ Ｋ 术后残余近视散光患者行再次 Ｐ Ｒ Ｋ 治疗, 并连续随访两年以上。术前残余球镜屈光度－ ３７５±１３２ Ｄ,残余柱镜屈光度－ ２３６±１２５ Ｄ, 最佳矫正视力均≥０８。结果： 术后 ６ 个月球镜屈光度－ ０３２±０２４ Ｄ, 柱镜屈光度－ ０７８±０５２ Ｄ, 裸眼视力≥１０ 者４６ 眼 （８８４６％ ）, 术后 ２４ 个月球镜屈光度－ ０３７±０４２ Ｄ, 柱镜屈光度－ ０５６±０３７ Ｄ, 裸眼视力≥１０ 者 ４２ 眼 （８０７６％ ）。最佳矫正视力下降 １ 行以上者 ３ 眼 （５７６％ ）, 实际球镜矫正度与预期矫正度相差１０ Ｄ 以内 ５０ 眼 （９０１５％ ）, 柱镜相差 １０ Ｄ以内５１ 眼 （９８０７％ ）。结论： Ｐ Ｒ Ｋ 治疗 Ｒ Ｋ 术后残余近视散光的两年随访结果表明, 该方法预测性强、稳定性好和安全性高, 特别在矫正残余散光方面, 其结果令人满意。     

PRK治疗近视术后2年随访分析

目的：评价准分子激光屈光性角膜切削术（ＰＲＫ）治疗轻、中、高度近视眼的临床效果。方法：对在我院接受ＰＲＫ治疗的２３９只近视眼的术后２年随访结果进行统计分析结果：Ⅰ组术前近视－１．００～－６．００Ｄ（等值球境，下同），术后２年裸眼视力≥１．０者占８７．１％，≥０．５者占９７．０％，剩余屈光度为－０．３４±０．３９Ｄ，９５．０％，角膜已完全恢复透明；Ⅱ组术前近视－６．２５～－１２．００Ｄ，术后２年裸眼视力≥１．０者占４７．８％，≥０．５者占８８．４％，剩余屈光度为－０．７７±０．６３Ｄ，７８．２％角膜已完全恢复透明。结论：ＰＲＫ治疗－１２．００Ｄ以下，特别是－６．００Ｄ以下近视眼安全有效，预测性及稳定性好     

准分子激光二次切削治疗近视性角膜切削术后欠矫

本研究共１５人（２３眼）于准分子激光角膜切削术后因欠矫而实施二次切削。术前平均屈光度为－９．８６Ｄ（－５．００—－２０．００Ｄ），其中２眼为中度近视（－３．２５—－６．００Ｄ），６眼为高度近视（－６．２５—－９．００Ｄ），１５眼为超高度近视（≥－９．２５Ｄ）。准分子激光二次切削采用治疗性角膜切削术（ＰＴＫ）和光学性角膜切削术（ＰＲＫ）相结合的方法。术后６个月随访结果表明：９１％的裸眼视力≥０．５，７０％的裸眼视力≥１．０，７０％的屈光度在±１．００Ｄ，角膜无明显混浊。由此证明：准分子激光二次切削治疗近视性角膜切削术后欠矫及角膜混浊是有效的。     

准分子激光屈光性角膜切削术治疗重度近视

目的 探讨准分子激光屈光性角膜切削术（ＰＲＫ）治疗重度近视的疗效。方法 使用Ｃｈｉｒｏｎ Ｖｉｓｉｏｎ的Ｋｅｒａｃｏｒ１１６准分子激光机,采用多光区切削方法治疗重度近视４９例８９眼,屈光度范围：－１０．００～－２５．００Ｄ。术后随访１ａ,并对结果进行分析。结果 ８９眼重度近视ＰＲＫ术后１ａ时,裸眼视力≥１．０者１２眼,占３．４９％,０．５～０。８者１７眼,占１９．１０％,≤０．４者６０眼,占７６７     

应用半硬性透气性接触镜（RGP）矫正散光的观察

选择角膜散光较大的屈光不正与无晶体眼和圆锥角膜患者共７６例１２４眼配戴ＲＧＰ角膜接触镜。矫正复性近视散光４８例（９０眼），ＲＧＰ镜片平均屈光度－８８７Ｄ±－４２６Ｄ；矫正无晶体眼１８例（１８眼），平均屈光度＋１１３５Ｄ±＋２４４Ｄ；矫正复性远视散光５例（８眼），平均屈光度＋６６８±＋２１４Ｄ。矫正圆锥角膜屈光异常５例（８眼），平均屈光度为－６１５Ｄ±－３７７Ｄ。矫正视力ＲＧＰ镜片优于框架球柱面联合镜片者５０眼（４０３％），两者视力相等者７１眼（５７３％），矫正视力低于框架者３只眼（２４％）。矫正视力１０以上者６０眼（４８４％），平均矫正视力０８６±０３。配适良好，合并症轻而少。ＲＧＰ的应用值得重视。     

准分子激光角膜切削术后屈光度过桥的临床分析

目的 探讨ＰＲＫ术后屈光度过矫的原因。方法 报告ＰＲＫ术后屈光度过桥４例（６眼），男性１例（２眼），女性３例（４眼）。结果 术前近视屈光度－３．０￣－６．０Ｄ，术后过矫屈光度＋１．２５￣３．７５Ｄ。随访６￣１２个月。有５眼随着角膜厚度的增加，角膜表面平均屈力的提高，过矫屈光度减小，裸眼视力提高至预期值，１眼无变化。结论 认为利用ＰＲＫ术后角膜上皮及胶原组织增生致远期屈光回退，通过密切监测角膜厚度、     

微型角膜刀板层角膜成形联合准分子激光角膜切削术治疗高度近视

为评价微型角膜刀板层角膜成形联合准分子激光角膜切削术（ＭＬＫ－Ｅ或ＬＡＳＬＫ）治疗高度近视的效果和安全性，利用微型角膜刀作一带蒂角膜瓣，在其下用ｓｃｈｗｉｎｄＫｅｒａｔｏｍⅠ型准分子激光机进行ＰＲＫ激光切削，共治疗了３０例４７眼，术前屈光状态＜－１５Ｄ的Ⅰ组共３５眼，屈光度为－１０．２０±２．０４Ｄ，最佳矫正视力为０．９２±０．２６（０．４—１．５）；等球镜≥－１５Ｄ的Ⅱ组共１２眼，屈光度平均为－１７．６４±１．８３Ｄ，最佳矫正视力为０．４２±０．２３（０．１—０．８）。散光最高为４．５Ｄ。结果：术后３个月随访：Ⅰ组：屈光度平均为－０．４８±０．５２Ｄ（－１．７５—＋０．５０Ｄ），裸眼视力３４眼（９７％）达到０．５以上（另１眼裸眼视力等于术前），２５眼（７１．４％）裸眼视力达到术前最佳矫正视力。Ⅱ组：屈光度平均为－１．４４±１．９７Ｄ（－５．５０—＋１．２５Ｄ），８眼（６６．７％）裸眼视力达到术前最佳矫正视力。是一种安全有效的高度近视治疗方法。     

PRK后2—3年的观察

本文报道１９３ｎｍ准分子激光角膜切削术（ＰＲＫ）矫正５３６例近视、屈光度为－２．２５～－１５．００Ｄ的９４２眼的疗效，随访２年至３年。术后随访，屈光度在±１．００Ｄ以内者：１年时，低中度组（≤６．００Ｄ）为８６．２％、高度组（＞６．００Ｄ）为６９．６％；２年时，分别为８４．７％和６７．８％；３年时，则分别为９２．３％和８５．７％。术后裸眼视力≥０．５和≥１．０者：１年时，低中度组为９９．３％和８７．６％、高度组为９６．１％和７１．６％；２年时，低中度组为９８．９％和８６．７％、高度组为９５．８％和７０．５％；３年时，低中度组为９６．８％和８８．９％、高度组为１００．０％和８５．７％。术后的角膜上皮下混浊多为０级和１级，极少或无３级及其以上的具有临床意义的角膜上皮下混浊。看来，ＰＲＫ为目前矫正近视的一种安全有效的术式     

Correction of myopia by PRK method with the use of MEL 80 excimer laser--initial report

PURPOSE: The aim of this study was to evaluate the effectiveness of PRK procedure by estimation: changes of visual acuity, refractive errors, IOP, pachymetry, high order aberrations before and after surgery. MATERIAL AND METHODS: In the First Department and Clinic of Ophthalmology Medical School 22 patients went through ophthalmological examination for PRK procedure. In this study we used MEL 80 excimer laser. There were 13 women (15 eyes) and 5 men (7 eyes). The myopia was corrected from -1.75D till -6.5D. The patients were from 22 to 41 years of age. RESULTS: The correction for myopia by PRK method with MEL 80 excimer laser is effective and safe laser procedure. Stabilization of the refraction post photorefractive keratectomy was after 2 months and there was no increase of intraocular pressure in all cases. The procedure increased the high order aberrations.     

Photorefractive keratectomy for residual myopia after cataract surgery

PURPOSE: To evaluate the effectiveness, predictability, and safety of photorefractive keratectomy (PRK) for correcting residual myopia and myopic astigmatism after cataract surgery with intraocular lens implantation. SETTING: Refractive Surgery and Cornea Unit, Instituto Oftalmológico de Alicante, Alicante, Spain. METHODS: Thirty consecutive eyes (30 patients) had PRK for residual myopia after cataract surgery. Surface PRK with a VISX Twenty-Twenty excimer laser was used in all patients. Follow-up was 1 year. RESULTS: Before PRK, no eye had an uncorrected visual acuity (UCVA) of 20/40 or better. Twelve months after PRK, 16 eyes (53.33%) had a UCVA of 20/40 or better. After PRK, best corrected visual acuity (BCVA) improved 1 line or more in 14 eyes (46.66%) over the preoperative values, and 15 eyes (50.00%) had the same BCVA as before PRK. Mean pre-PRK refraction of -5.00 diopters (D) +/- 2.50 (SD) decreased significantly to -0.25 +/- 0.50 D at 12 months (P < .001). At 12 months, the spherical equivalent was within +/- 1.00 D of emmetropia in 27 eyes (90.00%). No vision-threatening complications occurred. CONCLUSION: Photorefractive keratectomy was an effective, predictable, and safe procedure for correcting residual myopia and myopic astigmatism after cataract surgery.     

Repeated photorefractive keratectomy for undercorrection and regression

PURPOSE: Regression (often combined with significant haze) and undercorrection are the most frequent complications after photorefractive keratectomy (PRK) for myopia. PRK retreatment has been used to treat both of these complications. METHODS: Sixty-three eyes (55 patients) were reoperated (PRK) because of initial regression or undercorrection. The mean interval between the operations was 17.2 months (range 5 to 37 mo). Residual myopia before retreatment was less than -5.00 D in 62 eyes (mean -2.21 +/- 0.99 D) and was -10.50 D in one eye. The same surgical PRK technique (Aesculap-Meditec MEL 60 excimer laser with 5 or 6-mm ablation zone) was used in both operations. RESULTS: One-year results were available for 51 eyes. In the group of eyes with low residual myopia (<-5.00 D), mean refraction 1 year after retreatment was -0.42 +/- 0.96 D and 43 eyes (86%) were within +/-1.00 D of emmetropia. Uncorrected visual acuity of 20/40 or better was achieved in 43 eyes (86%) after 1 year. One eye lost two lines of best spectacle-corrected visual acuity after two procedures because of haze. Mean haze was the same before and 12 months after reoperation (grade 0.39 vs. 0.38). Significant haze (>2) and high regression after the first PRK occurred after reoperation. The one eye with -10.50 D residual myopia after the first PRK showed high regression, and 1 year after the reoperation refraction was -9.50 D with grade 2 haze. CONCLUSIONS: Repeated PRK was safe and in most cases effective in treating regression and undercorrection in eyes with low residual myopia after initial PRK. High regression and especially haze after the initial PRK often reappeared after reoperation.     

准分子激光屈光性角膜切削术后屈光回退的多因素分析

目的：探讨准分子激光屈光性角膜切削术后屈光回退的主要因素。方法：采用VISX20／20型准分子激光仪对121例214眼近视患者行准分子激光角膜切削术,术后随访2年。分二组进行比较,Ⅰ组为低中度近视（－1．00D－－6．00D）124眼,Ⅱ组为高度近视（－6．25D－－16．00D）90眼。结果：术后2年低中度近视回退率9．7％,高度近视回退率27．8％（P＜0．005）,高度近视中高龄组较低龄组回退率高（P＜0．005）,较严重的角膜上皮下雾状混浊与回退伴行。结论：准分子激光角膜切削术后屈光回退的主要因素有预期矫正屈光度,角膜Haze及年龄。     

Comparison of two procedures: photorefractive keratectomy versus laser in situ keratomileusis for low to moderate myopia

PURPOSE: A prospective study was conducted to compare the effectiveness, safety, and stability of photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) for correction of low to moderate myopia. METHODS: Forty-five patients with a manifest refraction (PRK, -4.54 +/- 0.80; LASIK, -4.82 +/- 1.10) from -1.50 to -6.00 diopters (D) were treated and followed-up for 6 months. In each case, 1 eye received PRK and the other LASIK. The first eye treated, and the surgical method used in the first eye, were randomized. Uncorrected and corrected visual acuity, manifest refraction, corneal haze, and topographic analysis of ablation decentration were examined. RESULTS: The uncorrected visual acuity was 20/20 or better in 35 PRK eyes (77.8%) and 28 LASIK eyes (62.2%) at 6 months (P =.107). At 6 months, 28 eyes (62.2%) that received PRK showed a spherical equivalent of within +/-0.5 D as compared with 24 eyes (53.4%) that received LASIK (P =.393). The amount of ablation decentration was 0.37 +/- 0.25 mm in PRK eyes and 0.49 +/- 0.38 mm in LASIK eyes at 3 months (P =.36). CONCLUSIONS: In our study, PRK and LASIK were found to be similarly effective and predictive of correction in low to moderate myopia. PRK has the advantage of less ablation decentration and is safer than LASIK, so we recommend PRK for eyes with low to moderate myopia.     

Comparison of photorefractive keratectomy and laser in situ keratomileusis for myopia of -6 D or less using the Nidek EC-5000 laser

PURPOSE: We compared the efficacy, predictability, and safety of photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) for the surgical correction of low and moderate myopia. METHODS: A retrospective study was performed to evaluate uncorrected and spectacle-corrected visual acuity, and manifest refraction 1 year after PRK or LASIK. All procedures were done using an automatic microkeratome (Chiron Ophthalmic) and the Nidek EC-5000 excimer laser. RESULTS: PRK was performed in 75 eyes of 45 patients and LASIK in 133 eyes of 77 patients. Mean age for PRK patients was 32.8 years (range, 18 to 52 yr) and LASIK patients was 29.6 years (range, 18 to 49 yr). Mean preoperative spherical equivalent refraction for PRK patients was -3.28 D (range, -1.00 to -6.00 D) and LASIK, -3.86 D (range, -1.00 to -6.00 D). One year after surgery, mean spherical equivalent refraction for Group 1 (baseline, -1.00 to -3.00 D) PRK eyes was -0.18 +/- 0.61 D (range, -1.50 to +0.75 D) and for LASIK eyes, -0.08 +/- 0.61 D (range, -1.50 to +1.62 D), with no statistically significant difference. For Group 2 eyes (baseline, -3.25 to -6.00 D), mean spherical equivalent refraction for PRK eyes was -0.44 +/- 0.87 D (range, -2.00 to +2.12 D) and for LASIK eyes, -0.09 +/- 0.83 D (range, -1.50 to +1.75 D), with no statistically significant difference. The antilogarithm of the mean UCVA (antilogUCVA) in Group 1 for PRK was 0.79 +/- 0.21 (20/25) and for LASIK was 0.87 +/- 0.19 (20/23), with no statistically significant difference. The antilogUCVA in Group 2 for PRK eyes was 0.70 +/- 0.24 (20/28) and for LASIK eyes was 0.83 +/- 0.18 (20/24), with a statistically significant difference (0.7 vs. 0.83, P < .005). The percentage of eyes with a postoperative UCVA >20/40 in Group 1 for PRK was 91.5% (38 eyes) and for LASIK was 95% (50 eyes) (no statistically significant difference), and in Group 2 for PRK eyes, it was 82% (27 eyes) and 97.5% (78 eyes) for LASIK (statistically significant difference, P < .05). CONCLUSION: PRK and LASIK with the Nidek EC-5000 excimer laser are effective and safe for correcting low to moderate myopia, but LASIK eyes showed better results for moderate myopia in terms of uncorrected visual acuity.     

Refractive results of post penetrating keratoplasty photorefractive keratectomy.

BACKGROUND AND OBJECTIVE: The aim of this study was to evaluate the safety, effectiveness, and predictability of photorefractive keratectomy (PRK) for severe myopia and astigmatism following penetrating keratoplasty. PATIENTS AND METHODS: PRK was performed on 42 eyes, and 33 eyes were followed up for at least 6 months. RESULTS: Mean preoperative spherical equivalent was -8.29 +/- 4.01 diopters (D), which decreased to -2.96 +/- 3.26 D in manifest refraction at 6 months. Keratometric power reduced from 48.06 +/- 3.32 D preoperatively to 43.97 +/- 3.40 D. Refractive and keratometric astigmatism attained the reduction of 31.0% and 13.56% in average respectively. Twenty three eyes had improved uncorrected visual acuity. CONCLUSION: PRK was effective in reducing post-keratoplasty myopia and astigmatism, but the predictability was not as good as in the non-grafted eye.     

准分子激光角膜原位磨镶术矫治高度近视准分子激光屈光性角膜切削术后屈光回退的临床观察

目的评价准分子激光角膜原位磨镶术（LASIK）矫治高度近视准分子激光屈光性角膜切削术（PRK）后屈光回退的疗效。方法回顾性临床研究。对PRK术后2年以上、屈光回退且屈光度稳定的患者8例14眼行LASIK,对LASIK术后术眼进行评价。患眼PRK术前屈光度为-6.25～-12.50 D,PRK术后屈光度为-1.50～-6.25 D。随访观察LASIK矫正1年后术眼的裸眼视力、最佳矫正视力、屈光度、上皮下雾状混浊（haze）形成和角膜厚度的变化。结果所有患眼术后主观症状较轻。LASIK术后1年平均球镜度数为（-0.62±0.94）D。LASIK术后0.5≤裸眼视力〈0.8者4眼,≥0.8者9眼,1眼（7.1%）最佳矫正视力下降2行。4眼术后出现不同程度的haze,包括2级haze 3眼、3级haze 1眼。应用氟米龙滴眼液1个月后,haze及屈光回退减轻;术后1年,1级haze 2眼,2级haze 2眼,3级haze 1眼。LASIK术前角膜厚度为（467±38）μm,术后为（422±21）μm。结论高度近视PRK术后屈光回退行LASIK矫治是一种可行的方法,但少数患者术后可出现haze,仍需治疗。     

Technical improvements in photorefractive keratectomy for correction of high myopia

PURPOSE: To evaluate the effects of hardware and software improvements in photorefractive keratectomy (PRK) for the treatment of highly myopic eyes. METHODS: A retrospective study was carried out in 554 patients (582 eyes) with myopia between -7.00 and -17.00 D (mean -11.20 +/- 3.60 D) who had undergone PRK using the Aesculap Meditec laser. Group 1 with a 5-mm-diameter single ablation zone; Group 2 with a 5-mm-diameter single zone surrounded by a 2-mm tapered transitional zone; Group 3 and Group 4, same as Group 2 but with the laser upgraded with a smoke aspiration control system (Group 3), and with a computer-controlled fluence (Group 4). RESULTS: In Group 1 at 2 years after PRK (50 eyes), 10 eyes (20%) were within +/-1.00 D of attempted correction and 13 eyes (26%) were within +/-2.00 D. In Group 2 at 2 years (118 eyes), 42 eyes (36%) were within +/-1.00 D of attempted correction and 65 eyes (55%) were within +/-2.00 D. In Group 3 at 2 years (43 eyes), 18 eyes (42%) were within +/-1.00 D of attempted correction and 28 eyes (65%) were within +/-2.00 D. In Group 4 at 2 years (47 eyes), 25 eyes (53%) were within +/-1.00 D of attempted correction and 29 eyes (62%) were within +/-2.00 D. CONCLUSIONS: Software and hardware improvements facilitated PRK correction of high myopia with reasonable predictability, especially if a tapered transition zone was used. At 12 and 24-month follow-up, only the use of a tapered transition zone was associated with a statistically significant improvement in predictability.     

PRK矫治近视远期临床疗效观察

目的 评价准分子激光角膜切削术(PRK)治疗近视远期临床疗效.方法 回顾性分析23例(45只眼)PRK术后8年以上(8.78±1.54)年的视力、屈光度、对比敏感度、波前像差及haze情况.分低度近视(＜-3D)、中度近视(≥-3D且＜-6D)和高度近视(≥-6D)三组比较.结果 低度近视组术后裸眼视力(UCVA)均≥1.0,中度近视组术后UCVA≥0.5和≥1.0者分别为:23只眼(85.19％),14只眼(51.85％);高度近视组达0.5以上为4只眼(40％).术后最佳矫正视力下降者三组眼数分别为0、5(18.52％)和3(30％).术后屈光度在预期矫正值±1D以内者三组眼数分别为8(100％)、17( 62.96％)、3(30％).中低度近视组对比敏感度均正常,高度近视组仅1只眼在正常值范围内.术后总高阶像差均方根三组间差异明显(P＜0.05),其中球差增大明显,且随矫正度数增加而增大(P＜0.05).haze低度近视组无,中度组仅1只眼(3.70％)为0.5级,高度组0.5级2只眼,1级2只眼.结论 PRK治疗中低度近视远期疗效满意,治疗高度近视远期效果欠佳,haze可在PRK术后长期存在,尤其在高度近视眼中.