Trends in Suicide by Poisoning in China 2000-2006： Age, Gender, Method, and Geography

Objective This study analyzed patterns of suicide and suicide attempts by poisoning as reported through a national poison control system for the purpose of improving intervention and prevention. Methods During the period of 2000 to 2006, 6440 cases of poisoning suicide were reported to the telephone consultation service system of The National Center for Poisoning Control （Chinese Center for Disease Control and Prevention）. Among these records, 4728 cases had completed data for this analysis in terms of age, sex, trend of time and location, and type of poisons. Results There were 60.6% female cases with the age from 10 to 90 years old. The age of cases from 20 to 39 years accounted for 54.5% of all age groups. Both the numbers and percentage in record related to poisoning consultation of oral poisoning suicide showed an increasing tendency during the 7 years. In particular, there was a drastic increase from 2004 to 2006. In addition, the high frequency of cases occurred from May to October. Hebei, Shandong, Henan, and Anhui Provinces had the highest number of cases. Pesticide poisonings were the most common method in these cases of consultation for suicide and suicide attempts. Conclusion This study describes epidemiological characteristics in the oral poisoning suicide cases and provides scientific basis for suicide prevention interventions.     

海口市2010—2020年输入性登革热流行病学特征

Objective This study intends to understand the epidemiological characteristics of imported dengue fever in Haikou city from 2010 to 2020, we provide references for dengue fever prevention and control in Haikou city. Methods The epidemiological investigation and laboratory nucleic acid test data of dengue fever cases in Haikou City from 2010 to 2020 were collected, and analyzed by Excel 2010 and SPSS 20.0 software, to describe the epidemiological characteristics of imported dengue fever cases. Results A total of 72 cases of imported dengue fever were reported in Haikou City from 2010 to 2020, 53 cases were imported from abroad (73.61%) and 19 cases were imported domestically (26.39%), all of which were mild. The number of imported cases from 2017 to 2019 increased by 1 321.68% compared with the average annual imported cases from 2010 to 2016. The cases were concentrated in the main urban area (97.22%), distributed in the streets in the main urban area. The peak of case imported occurred in August-November,in addition, the domestic imported cases were concentrated in September-October. The ratio of male to female was 2.27∶1, and the average age was (34.93 ±1.55) years old. Working, doing business and visiting relatives accounted for 84.22% in China. Overseas workers, business and tourism accounted for 77.78%. There was a significant difference in the reasons for going out between domestic and overseas imported cases (χ2=75.10,P< 0.05). Among the imported sources, Southeast Asia accounted for 94.34% of overseas imported cases, and Guangdong Province accounted for 57.89% of domestic imported cases. The median of onset to diagnosis was 3 days, the first diagnosis rate was 77.78% (56/72), and the screening rate of people who have been infected before entering the country was 28.57%. Most of the dengue viruses infected were type I and type II, accounted for 84.72%. Conclusion The imported cases of dengue fever in Haikou city have gradually changed from scattered occurrence to rapid growth; we should strengthen the publicity and education of dengue fever among migrant workers, businessmen, tourists and relatives in the main urban area of Haikou City, and improve the awareness of disease prevention and medical treatment, strengthen quarantine inspection and medical examination of entry personnel from Southeast Asian countries as well as dengue fever diagnosis and treatment training in grass-roots medical institutions, which can effectively reduce the risk of local transmission caused by imported dengue fever cases. © 2021 Editorial Office of Chinese Journal of Schistosomiasis Control. All right reserved.     

A serological study of hepatitis C infection in plasmapheresis donors.

An epidemic of parenterally transmitted non-A, non-B hepatitis (PT-NANBH) occurred in plasmapheresis donors in Guan County, Hebei Province, China, in 1985. PT-NANBH was diagnosed by epidemiological studies and serological exclusion of HAV, HBV, CMV and EBV infections. Recently, 163 sera samples of 108 patients with PT-NANBH and 65 sera samples of 49 cases with elevated alanine aminotransferase (ALT) levels collected during the epidemic were tested by anti-HCV EIA (Chiron C100). The positive rates of anti-HCV in these two groups were 89.8% (97/108) and 93.9% (46/49), averaging 90.8%. The figures increased with the course of illness and persistance of ALT elevation, i.e., 17.6% and 55.6% within 1 month, 88.9% and 87.5% at 6 months and 100% and 100% after 2 years. Five patients with PT-NANBH and 1 with elevated ALT levels were followed up for 3 to 4 years. We demonstrated that anti-HCV remained positive after the disease had resolved and ALT levels had normalized.

     

Epidemiological survey of primary palmar hyperhidrosis in adolescents

Background Despite recent advances in recognition and treatment of primary palmar hyperhidrosis (PPH), the epidemiological survey has hardly been conducted. The aim of this study was to investigate the prevalence and epidemiological characteristics of primary PPH among adolescents in three cities of southeast China. Methods Stratified-cluster sampling was carried out and cross-sectional epidemiological survey by questionnaire was applied among 33 000 college and high school students. Results The prevalence rate of PPH was 4.36% affecting both sexes equally. Prevalence rate of severe PPH was 0.27%. The average age of onset was 12.27±2.12 years. The peak age of onset was 6–16 years, accounting for 97.2% of PPH population. Positive family history was found in 17.9% PPH cases. Besides palms, axillae and soles can be also affected. Conclusions PPH affects a larger group of individual than previously reported. More measures should be taken to enhance the recognition, diagnosis, and treatment of PPH.     

Implication of Reported Viral Hepatitis Incidence Rate Change in Hubei Province, China, between 2004-2010

This study examined the change of reported incidence rate for viral hepatitis in Hubei province, China, between 2004 to 2010 to provide scientific evidence for viral hepatitis control. Reported viral hepatitis infection cases were queried from Centre for Disease Control of Hubei Province, China. The incidence of viral hepatitis A decreased steadily across the study period. Viral hepatitis B composed 85% of the viral hepatitis cases. When reported incidence rates for chronic hepatitis B increased, the rates of acute and unclassified cases dropped from 2005 to 2010. The reported viral hepatitis B incidence rate for males was around 1.5-2 times higher than for females. The average annual percentage change of reported viral hepatitis B incidence rates was 4%. The same index for viral hepatitis C was 28%. The reported viral hepatitis B incidence rate of people under 20 years old declined over the period. This decrease was mainly attributed to the recent implementation of vaccination plan. Reported incidence rate of viral hepatitis E also rose in those years. Having a better understanding on reported incidence rates of the present surveillance system is important for developing strategies for further prevention of viral hepatitis. In addition, the data showed that a surveillance system that differentiates new and former infected cases will be more effective in providing evidence for disease control.     

Epidemic non-A, non-B hepatitis in Xinjiang. Clinical and pathologic observations

131 cases of epidemic hepatitis from two villages in Xinjiang, were admitted to the provisional infectious diseases hospital from February to April 1987. In 125 (95%) patients neither anti-HAV IgM nor anti-HBc IgM were positive. 118 (90%) were drinking water from a local stream of the Hotan River. The study was conducted on 125 patients aged from 5 to 90 years, with a mean of 26.4 years. There were slightly more males than females, a ratio of 1.5 to 1. The incubation period was roughly estimated to be 17 to 37 days (mean 24.8 days). All subjects were jaundiced. 12 patients (including 6 pregnant women) had cholestatic symptoms. Except one woman who died of postpartum bleeding, all patients ran a benign course without fulminant hepatic failure. Pathologic changes of liver biopsies from 35 cases included lobular damage and inflammation, ballooned hepatocytes with clear cytoplasm and delineated cell membrane which were named "clear cell". There were cholestasis of different degrees in the acute icteric stage and fatty changes in the convalescent stage. It was seen under the electron microscope that the livers of 8 cases had neither tubular structure nor sponge-like inclusions, but had nuclear changes including curled edge of nuclear membrane and nuclear heterochromatin condensed in masses. Liver biopsies were repeated in 7 cases followed up for 6-13 months, and hepatohistology was normal in 5. Of the other two cases there was one of each.

     

Twenty-five Cases of Obstinate Hiccup Treated by Point Injection at Tianding

From 1997 to 2000,the author treated 25 cases ofobstinate hiccup by injecting chlorpromazine and654-2 injection at Tianding(LI 17),withsatisfactory therapeutic results as reported in thefollowing.General DataOf the 25 cases in this series,18 cases were male,and 7 female,ranging in age from 17 to 65 years.The course of disease was 3 to 7 days in average.     

TWENTY-THREE YEAR''S RESEARCH ON PREVENTION OF CERVICAL CANTCER

Preventive mass screening was conducted every l-2 years in 42 textile factories from 1958- 80 in Shanghai. A total of 846,104 examinations was made, and the percentage of women ex- amined was 70-90%. In 23 years the age- standardized prevalence rate was lowered by 97.6%. 520 cases of cervical cancer were fonnd, among them 465 patients are still alive. The 10-year survival rate (life-table method) was 93.1%, and the 20-year, 86.1%. There were rio stage IV, III and II cases in recent 18, 8 and 7 years, respectively. In the past 8 years, all 45 cases except one were of subclinical type. The average incidence rate of cervical cancer ranked 5th among all malignant cases at these factories, whereas the mortality rate came down to the last. The prevalence rate of cervical cancer in the ≥40 year old group was over 3 times higher than in the <40 year old group. During the 23 years the median age of cervical cancer patients was postponed by 8.7 years. The disease has not been discovered in <40 year old women in the last 3 years. Carcinoma in-situ was not detected in the <40 year old group in the last 8 years. The prevalence rate of cervical atypical hyperplasia in the ≥40. year old group was 7.5 times higher than in the group. of <48 years. Therefore women ≥40 years, old are the high risk group in our series.     

50例产单核细胞李斯特菌血流感染分析

Objective To analyze the characteristics of bloodstream infection of Listeria monocytogenes and provide basis for the diagnosis and treatment of the disease. Methods We retrospectively analyzed the cases of Listeria monomyrhosi bloodstream infection in Peking Union Medical College Hospital (PUMCH) from April 2012 to April 2022. The age, sex, onset time, underlying disease, symptoms, diagnosis, treatment and prognosis of the patients were analyzed, as well as the changes of white blood cells (WBC), neutrophils, lymphocytes, and C-reactive protein (CRP) before and after anti-infection treatment. Results Fifty cases of Listeria monocytogenes bloodstream infection confirmed by blood culture were involved. The age of patients ranged from 0 to 82 (43.7±20.0) years old, among whom 20.0% were over 60 years old. The onset time of patients was the highest in spring (44.0%), followed by winter (24.0%), and relatively fewer in summer and autumn (14.0%-18.0%). The median diagnosis time was 3 days (1-60 days). After the etiological diagnosis, 45 patients (90.0%) had underlying diseases or pregnancy status, and 45 patients were adjusted to the target antibacterial treatment mainly with carbapenems (48.9%) and penicillins (44.4%). The level of WBC, neutrophils, lymphocytes, monocytes, and CRP after treatment were significantly lower than those pre-treatments (P<0.05). Among all patients, 36 cases (72.0%) were treated according to the Antimicrobial Treatment Guidelines for Fever Sanford, of which 26 cases (72.2%) were discharged from the hospital, two cases died, one case was transferred to other hospitals, and 7 cases had a poor prognosis. Conclusions Autoimmune diseases, tumor diseases, pregnant patients are susceptible to Listeria monocytogenes infection. Penicillins are the first choice for effective empiric therapy. For the patients allergic to penicillins, trimethoprim/sulfamethoxazole or meropenem could be used. © 2023 China Tropical Medicine. All rights reserved.     

河北省新型冠状病毒肺炎流行特征与时空聚集性分析

目的 通过对河北省新型冠状病毒肺炎(COVID-19)的流行特征与时空聚集性进行分析,为河北省疫情防控及相关政策的制定提供科学依据。 方法 收集河北省2020年1月22日至2月27日COVID-19疫情数据,揭示该省疫情的流行特征;采用时空扫描的方法对疫情的聚集性进行分析。 结果 2020年1月22日河北省石家庄市报告首例COVID-19确诊病例,截至2月27日全省共报告COVID-19病例318例,其中包括湖北(含武汉)输入病例80例(25.16%),武汉输入病例69例(21.70%);全省病例男女比例为1.06∶1,30~69岁(70.76%);2月5日至2月10日为疫情高峰期,2月7日单日最高确诊24例,随后确诊病例逐渐下降,截至3月12日已连续14 d无新增确诊病例;河北省11个地市均发现COVID-19疫情,疫情覆盖范围达河北省82个区(县)(82/175,46.86%),其中疫情最严重的区(县)为唐山市迁安市(30例);11个地市均发生了聚集性疫情,共发现聚集性病例239例,其中110例(46.03%)是家庭聚集性传播导致。唐山市迁西县、遵化市及迁安市的时空聚集性最高,聚集时间为2月5日至2月15日(RR=15.69,LLR=61.75,P<0.01)。 结论 河北省COVID-19疫情为全人群普遍易感,早期以境内省外输入性病例(以下简称“输入性病例”)为主,后期以本地病例为主,全省聚集性疫情占2/3,未发现医务人员感染,国家启动一级响应后,目前疫情已得到有效控制,但随着复工复学的逐步推进和境外输入病例、无症状感染者的增加,仍需加强常态化疫情防控,巩固疫情防控向好态势。     

四川省达州市42例新型冠状病毒肺炎病例的流行特征

目的 分析达州市新型冠状病毒肺炎(新冠肺炎)病例流行病学特征,为达州市新冠肺炎防控提供科学依据。方法 对2020年1—2月达州市报告的42例新冠肺炎病例资料进行统计分析。结果 达州市7个县(市、区)均有病例报告,人群以30~<50岁为主,无未成年人确诊病例报告;发病高峰在2020年1月26日—2月5日,临床症状以发热(59.52%)和咳嗽(64.29%)为主,早期CT检查肺部异常率90.48%;19例输入性病例中18例有武汉旅居史或停留史;患者发病到住院、确诊到出院和持续排毒时间中位数分别为5.5 d、18.5 d和7.0 d,四分位数间距分别为5.5 d、8.0 d和 6.0 d。结论 达州市1月份以输入性疫情为主,2月份本地病例不断增加,2月下旬疫情逐渐控制;将发热、咳嗽作为新冠肺炎临床筛查指征,CT检查可作为早期筛查手段;患者住院时间和持续排毒时间较长,应做好长时间治疗准备及治疗过程中心理疏导,提高患者配合度;达州市聚集性疫情程度较重,基层工作有差距,新周期需进一步落实各项防控工作,严防因境外输入引发本地病例。     

延安市新型冠状病毒肺炎流行病学特征分析

目的 分析延安市报告的新型冠状病毒肺炎(COVID-19)病例的流行病学特征,为开展疫情防控提供参考。方法 收集2020年1月22日至6月19日延安市疾控中心检测确诊的COVID-19病例数据信息,采用描述性流行病学方法,分析COVID-19的流行情况和分布特征。结果 共检测送检样本1070例,核酸检测确诊呈阳性者8例,阳性检出率0.78%。病例感染来源以输入性为主,主要分布在宝塔区和延川县,发病中位年龄38.3岁,集中在18~45岁(占50%)。确诊病例的临床分型以普通型为主,从发病到确诊平均间隔3 d。发生一起家庭聚集性疫情,涉及5例病例。结论 延安市COVID-19病例感染来源以输入性为主,疫情风险等级处于低风险区,但是仍需要坚持“外防输入、内防反弹”的防控策略,全力做好常态化疫情防控工作,持续巩固防控成果。     

安徽省新型冠状病毒肺炎流行病学特征及其潜伏期估计

目的 分析2020年1月22日至2020年3月8日安徽省新型冠状病毒肺炎流行病学特征并估计其潜伏期,为进一步认识新型冠状病毒肺炎的传播规律和制定区域性的疫情防控措施提供依据。 方法 基于安徽省及其各个地市卫生健康委员会官网公布的新型冠状病毒肺炎病例资料,采用空间自相关统计方法进行全局及局部聚集性分析,揭示安徽省新型冠状病毒肺炎流行病学特征;根据病例的暴露和发病时间,估计新型冠状病毒肺炎潜伏期分布特征。 结果 安徽省共报告新型冠状病毒肺炎确诊病例990例,死亡病例6例,粗病死率为0.61%。自安徽省首例确诊病例以来,确诊人数迅速增多,2月6日出现单日最多确诊病例74例,而后逐渐下降。确诊病例年龄最小8个月,最大91岁,主要集中在31~60岁(65.19%),男女比1.16∶1,具有一定的聚集性,1月22日至1月29日期间,具有湖北省暴露史病例占比高达75%,随后明显下降。截至3月8日,安徽省16个地市均有确诊病例报告,其中合肥、阜阳、蚌埠为本次疫情受影响较大的地区,病例分布存在明显的空间自相关性。1月31日前,病例增长以湖北省输入病例为主,本土病例散在发生,随后逐渐转向本地接触传染扩散为主。Gamma分布拟合潜伏期效果较好,以此估计安徽省新型冠状病毒肺炎的中位潜伏期为5.64(95%CI: 5.11~6.22)d。 结论 安徽省新型冠状病毒肺炎流行特征与其他省份基本一致,前期疫情防控工作已取得阶段性成效,随着各地复工、复产等各项工作的推进,需巩固疫情防控成效,积极防治疫情反弹。     

宁夏2020—2021年新型冠状病毒肺炎网络直报质量评价

目的 通过对宁夏报告的新冠病毒肺炎病例传报卡及初筛阳性报告信息开展质量评价,发现存在的问题,为进一步提高新冠病毒肺炎报告信息质量提供参考。方法 从中国疾病预防控制信息系统中按终审日期导出2020—2021年的全部新冠病毒肺炎个案卡及2021年新冠病毒肺炎初筛阳性卡片,对个案卡报告及时性、审核及时性、报告完整性、准确性等开展分析。结果 宁夏2020年1月20日报告首例新冠病毒肺炎病例,截至2021年12月31日,累计报告确诊病例122例,无症状感染者4例。2021年新冠病毒肺炎病例报告及时率为98.00%,较2020年（90.54%）上升8.24%,与2020年相比,2021年新冠病毒肺炎病例/无症状感染者诊断到报告的平均时限缩短了83.12%;2021年新冠病毒肺炎病例审核及时率为100.00%,较2020年（87.84%）上升13.84%,与2020年相比,报告到终审的时间缩短了98.91%。2021年宁夏新冠病毒初筛阳性报告及时率90.00%,其中县（区）级核酸检测机构报告及时率最高（92.31%）,其次为市级（91.67%）,自治区级最低（81.82%）。结论 2020年疫情初始,宁夏新冠病毒肺炎病例报告时效性较差,通过技术培训、督导检查、不断优化医疗机构及疾控机构人员配置等措施,2021年宁夏新冠病毒肺炎病例报告时效性有大幅度提升,但仍然存在一些薄弱环节。在今后的工作中要针对薄弱环节开展技术指导和培训,努力提高报告质量。     

湖南省郴州市新型冠状病毒肺炎突发公共卫生事件报告质量及问题探讨

目的 评价湖南省郴州市新型冠状病毒肺炎突发公共卫生事件网络报告质量,为进一步提高新发传染病网络报告质量提供科学依据。方法 采用描述性流行病学方法对郴州市新型冠状病毒肺炎突发公共卫生事件报告数据进行分析,并根据定义监测指标评估事件监测报告质量。结果 截至2020年3月4日郴州市共报告17起新型冠状病毒肺炎突发公共卫生相关事件,均为未分级事件,聚集性疫情波及人口的罹患率为2.00%~83.33%。9起事件已结案,其中1起事件中出现出院病例核酸复检阳性。报告时效值为（0.56±0.44） h,监测敏感值平均为4.54 d,信息完整率和准确率均为100%。结论 新冠肺炎突发事件均报告及时、信息报告完整且准确,但是监测敏感性滞后;事件进程中要根据疫情进展,及时、准确评估疫情并对事件定级。事件中末例病例出院后随访至少28 d,相关危险因素消除后再对事件进行结案评估。     

基于人口流动的海南省新型冠状病毒肺炎输入风险和防控效果评估

目的对海南省各市县2020年1月10日—3月7日新型冠状病毒肺炎输入风险进行评估,并对2021年春运期间采取“常态化防控”措施效果进行评估。方法收集海南省每日报告输入病例数及30个省份每日报告病例数和百度迁徙指数,计算海南省各市县输入风险指数,对全省及各市县输入风险进行量化评估。分析输入风险指数与输入病例间关系,据此构建“疫情应急围堵”阶段输入病例拟合模型,预测2021年春运期间仍然采取“应急围堵”策略可能的输入病例数,与实际输入病例数相比较,以评估2021年春运期间采取“常态化”疫情防控策略的效果。结果海南省报告输入病例112例,平均输入风险指数为0.98。海口市、三亚市和儋州市输入风险最高,除海口外,各市县输入风险指数1月24日左右达到最大值,以滞后4 d和5 d输入风险指数构建的两阶段广义相加模型对输入病例数的拟合程度最好(R^(2)_(adjust1)=83.50%,R^(2)_(adjust2)=82.00%,MRE=17.61%)。如继续采取“应急围堵”策略,预计2021年春运期间海南省将有10例输入病例,“常态化”防控策略下,实际上海南省无输入病例发生。结论海口和三亚等旅游城市输入风险较高,湖北省和广东省是主要的疫情输入省份,广义相加模型可以较好地对“应急围堵”阶段海南省新冠肺炎输入病例进行拟合。与“应急围堵”策略相比较,2021年春运期间采取的“常态化”疫情防控策略使海南省减少了约10例输入病例。     

云南省新型冠状病毒肺炎疫情空间分析

目的 分析云南省新型冠状病毒肺炎疫情的空间分布特征,为制定云南省疫情防治措施和疫情的有效控制提供有效参考。方法 2020年1月23日至2月22日期间,基于全云南省通过疫情信息报告管理系统进行网络报告的新型冠状病毒肺炎疫情数据和云南省统计局统计的云南省常驻人口信息,导入GeoDa1.14.0和Mapinfo15.0软件,进行云南省新型冠状病毒肺炎疫情的描述和空间自相关分析。结果 全省16州（市）除迪庆州和怒江州无病例报告外,其他14个州（市）均有病例报告,其中确诊报告数主要集中在经济较发达的地区和旅游业较发达地区,云南省新型冠状病毒肺炎疫情出现先急剧升高后缓慢下降的趋势,发病率全局的空间自相关无统计学差异,但局部有一定的聚集,局部地区聚集情况仅出现在疫情较早期,疫情早期存在3个L-L聚集区（德宏州、版纳州和昭通市）,1个H-L区（昆明市）,4个L-H 区（玉溪市、曲靖市、楚雄州和红河州）,随着时间的推移,空间聚集情况逐渐消失。结论 目前疫情可防可控,无空间聚集性,但是在疫情完全扑灭前,仍然需要我们提高警觉性,科学防控,避免疫情的再燃和空间的聚集。     

北京市境外输入新冠肺炎病例流行病学特征及防控措施探讨

目的 分析北京市境外输入新型冠状病毒肺炎（简称新冠肺炎）病例流行病学特征及口岸防控措施效果,为构建科学有效境外输入疫情防控体系提供参考依据。 方法 收集北京市2020年2月29日—2021年10月29日境外输入新冠肺炎病例,从诊断类别、临床分型、人群分布、时间分布、来源国分布、诊疗情况等进行统计分析。结果 境外输入新冠肺炎病例436例,其中确诊病例297例,无症状感染者139例。确诊病例中轻型126例,普通型171例,无重型、危重型病例,无死亡病例。境外输入病例男女比例1.32:1,年龄中位数28（22,38）岁,以20~<40岁261例,占59.86%。病例来源国分布在48个国家或地区（包括中国台湾、香港）,前三位分别为英国（91例,占20.87%）、西班牙（48例,占11.01%）、菲律宾（41例,占9.40%）。境外输入病例入境到诊断时间间隔中位数为4 （1,28） d,确诊病例入境到诊断时间间隔短于无症状感染者,差异有统计学意义（t=2.163,P=0.032）。境外输入病例诊断至治愈时间间隔中位数为17（12,28）d,确诊病例诊断至治愈时间长于无症状感染者,差异有统计学意义（t=10.968,P<0.000 1）。结论 北京市境外输入新型肺炎病例具有较明显的流行病学特征,外防输入是疫情防控工作的重点,口岸是重中之重。     

西安市新型冠状病毒肺炎疫情分析

目的 分析西安市新型冠状病毒肺炎(COVID-19)疫情的流行特征,为疫情防控提供参考依据。 方法 从西安市卫生健康委员会和陕西省卫生健康委员会官方网站收集西安市COVID-19疫情病例个案信息资料,采用Wilcoxon秩和检验和Kruskal-Wallis H检验及描述性流行病学方法进行分析。 结果 截至2020年3月31日西安市累计报告COVID-19确诊病例125例,其中男67例,女58例,13~89岁,平均(48.23±15.94)岁,35~54岁55例(44%)。含输入性病例52例,本地续发病例73例;流行病学史明确者117例,接触史不明者8例;死亡3例。共报告聚集性疫情23起涉及病例89例,其中家庭聚集性疫情13起(56.52%),涉及病例38例(42.70%)。报告病例数居全市前3位区县依次是雁塔区(29例)、新城区(20例)和莲湖区(16例)。流行曲线显示前两次疫情高峰分别出现在1月28日(11例)和1月31日(10例)。病例从发病到首诊时间1.0(0.5,3.0)d,从首诊到确诊时间4.0(3.0,6.5)d,从发病到确诊时间7.0(4.0,10.0)d。输入病例和续发病例从首诊到确诊时间差异有统计学意义(Z=-2.107,P=0.035);首诊前服药和未服药病例从发病到确诊时间差异有统计学意义(Z=-2.690,P=0.007)。 结论 西安市COVID-19 疫情可分为外省市输入病例、本地续发病例和境外输入病例三个阶段,以家庭聚集性发病为主要流行特征。输入病例比续发病例更早确诊,首诊前是否服药可影响COVID-19确诊。防止境外病例输入是目前西安市疫情防控的重点。