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Tear function and goblet cell density after pterygium excision   总被引:2,自引:0,他引:2  
Li M  Zhang M  Lin Y  Xiao Q  Zhu X  Song S  Lin J  Chen J  Liu Z 《Eye (London, England)》2007,21(2):224-228
PURPOSE: To evaluate the short-term effect of pterygium excision on tear function and conjunctival goblet cell density. METHODS: In all, 70 patients (70 eyes) with primary pterygia who underwent a bare-sclera procedure were enrolled in this study. Tear break-up time, Schirmer, and tear-ferning tests and conjunctival goblet cell density obtained by impression cytology were evaluated before and 1 month after surgery. RESULTS: At 1 month postoperation, the tear break-up time (11.49+/-3.76 s) was significantly prolonged when compared with the preoperation tear break-up time (9.74+/-3.43 s, P=0.002). Before surgery, only 17% of the patients showed normal crystallization in the tear-ferning test. This proportion was significantly increased to 90% 1 month after surgery (P<0.001). There is no significant difference in the Schirmer test value between pre- and postsurgery (P>0.05). The mean goblet cell density in conjunctival impression specimens before surgery was 41.82+/-18.29/10 fields, which was increased significantly 1 month after surgery (P<0.001) with a mean cell density of 50.67+/-18.71/10 fields. CONCLUSION: Tear function in patients with primary pterygium improves after pterygium excision, which indicates that pterygium has a close relationship with dry eye.  相似文献
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联合自—异体板层角膜移植减少排斥反应研究   总被引:2,自引:0,他引:2  
目的观察联合自异体板层角膜移植术对植片免疫排斥反应的发生率及疗效。方法对23例(24只眼)已切除侵犯瞳孔区的翼状胬肉及中央板层角膜患者,分别在周边和中央行自异体植片移植术。另与单纯行胬肉或角膜皮样瘤切除、原位异体板层角膜移植术的13例(13只眼)患者进行对照,比较其排斥反应的发生率和疗效。结果自异体移植组的植片全部透明,无一例发生排斥反应和翼状胬肉复发。对照组则有30.8%发生排斥反应,20.0%翼状胬肉复发。结论联合自异体板层角膜移植术可减少排斥反应及翼状胬肉的复发  相似文献
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