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Valiriana Jatamansi(VJ),a Chinese herb wasfound effective against rotavirus enteritis in clinicalpractice.Animal experiments carried out by theInstitute of Medical Biology in Kunming have alsodemonstrated the efficacy of VJ.From December 22,1982 to January 4,1983,102 patients with rotavirus enteritis were admittedto our hospital.Of these 74 cases were randomlydivided into 3 groups:Group A(46 cases),GroupB(12 cases) and Group C(16 cases).In group A,the VJ-treated group,the drug was given orally ata dosage of 5 ml every 6 hrs for patients under 1year;10 ml every 6 hrs to patients over 1 year.Ingroup B,the control group,a solution of vitaminsBoo.and C was given orally.In group C,the West.ern medicine treated group,Gentamycin or SMZwas given in common dosage.Groups A and C werealso given the vitamins Bco.and C orally as in groupB.Patients with water and electrolyte disturbancein all groups received fluid therapy as indicated.Within 72 hours of medication the rate of cessa-tion of diarrhea in groups A,B and C were 73.92%,41.67% and 56.25% respectively.The rate in groupA was considerably higher than group B.Percentagesof patients whose temperature returned to normalafter treatment in groups A,B and C were 90.64%,60%and 92.30% respectively,suggesting antipyreticeffect of VJ. 相似文献
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This article deals with studies in late
autumn 1981 0f the infection of wild adult
Tupaia belangeri yunalis (a species of tree shrew
caught in autumn in Yunnan province) with
human rotavirus., 12 tupaias are infected in the
first passage, 3 in the second passage and 3 in
the third passage, 12/12, 2/3 and 2/3 0f the tu-
paias develop diarrhea during the 3 passages.
Electron microscopic observat.ion shoiws that
12/12, 3/3 and 2/3 0f the tupaias excrete rota-
virus during the passages. Three tupaias died
during the first passage and show mucosal ne-
crosis and lymphocyte infiltration in sections of
different intestinal parts. Immune electron mi-
croscopically, anti-rotavirus antibody is assayed
in sera of 2 infected tupaias, in both of which
titer rises greater than 4 fo.lds in the convalescent
phase serum as compared with the pre-infection
serum. These results indicate that the adult
tupaia is probably susceptible to human rota-
virus. 相似文献
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中草药“秋泻灵”实验治疗树鼩人工感染轮状病毒肠炎的研究 总被引:1,自引:0,他引:1
本文报道用中药“秋泻灵”治疗实验感染树鼩轮状病毒肠炎的结果,并与ORS治疗组和不治疗对照组进行了比较,用“秋泻灵”治疗的6只动物,平均止泻18小时,平均失重2.5克,全部治愈,ORS治疗的5只动物,平均止泻56小时,失重6.6克,其中1只死亡,未治疗对照组的5只动物平均止泻93小时,失重6.8克,其中3只死亡,4只死亡动物肠组织切片有粘膜坏死及淋巴细胞浸润,结果表明:“秋泻灵”是一种比ORS好的治疗轮状病毒肠炎的药物。 相似文献