Differential expression of salivary S100A7 in oral submucous fibrosis

Aim

To investigate the expression of salivary S100A7 levels among patients with oral submucous fibrosis (OSF) and healthy controls.

898例2型糖尿病中医证型分布规律及其相关因素回顾性研究

目的：对2型糖尿病患者进行回顾性研究,探讨中医证型分布和相关因素之间的联系。方法：将湖南省卫生健康委信息统计中心的三甲中医院病历数据进行筛选、清理,最终选取898例患者作为研究对象,并进行回顾性分析,研究患者中医证型并分析证型与年龄、性别、实验室指标之间的关系。结果：898例2型糖尿病患者中证型最多的为肝肾阴虚,合并疾病较多的是心脑血管疾病;在年龄与性别方面,不同中医证型患者分布,差异有统计学意义（P<0.05）;实验室指标方面,糖化血红蛋白（HbA1c）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）、三酰甘油（TAG）、血肌酐（Cr）、血尿素氮（BUN）、谷草转氨酶（GOT）、平均血小板体积(MPV)、纤维蛋白原（FIB）不同证型间分布差异均有统计学意义（均P<0.05）,其余指标不同证型间比较差异无统计学意义（P>0.05）。结论：性别、年龄、实验室指标可以在一定程度上反映出2型糖尿病不同中医证型的区别,对于2型糖尿病的治疗应及时检测以上指标的水平值,并明确相应的证型,针对性地给予辨证论治或中西医结合治疗,在疾病的中后期要预防心脑血管疾病以及各种并发症的发生,改善患者的生命质量。     

院前急救创伤数据库的构建及应用

目的 为实现我院创伤患者院前急救病历的信息化管理,为今后分析创伤患者的院前急救资料提供依据.方法 在日常工作中利用我院自行设计的院前急救电子病历录入创伤患者临床资料,所有数据以报表的形式导入SPSS软件,从而建立SPSS数据库.结果 通过院前急救电子病历完成本市急救中心2007年全年创伤病例l 650例,录入便捷,资料全面准确,数据库具备统计分析、检索查询、资料共享等功能,有效服务于临床科研及教学.结论 在日常工作中保证了电子病历资料完整性、准确性,而快捷录人数据建立的院前急救创伤数据库,显著降低临床、科研工作量,实现了院前急救创伤患者临床资料的信息化管理.     

复方维生素C银翘双层片的制备及其稳定性研究

选用利于维生素C稳定的辅料,采用双层压片工艺制备了复方维生素C银翘片,并对其含量测定方法进行了改进。稳定性加速试验研究表明,双层片稳定性比市售片有极显著提高（P＜0．01）,可达到两年以上。     

Weekend catch-up sleep and depression: results from a nationally representative sample in Korea

BackgroundThere is limited information on the association between weekend catch-up sleep (CUS), which has beneficial effects on health, and depression. This study aimed to investigate the association between CUS and depression in adults.MethodsWe used the data of the Seventh Korea National Health and Nutrition Examination Survey, 2016. Depression was defined as Patient Health Questionnaire-9 score ≥10. We categorized CUS duration as ≤0, 0 < to 1, 1 < to 2, and >2 h.ResultsOf 5550 eligible participants, 3286 (54.9%), 1033 (19.5%), 723 (14.7%) and 508 (10.9%) had CUS duration ≤0, 0 < to 1, 1 < to 2, and >2 h, respectively; of these, the prevalence of depression was 7.0%, 4.2%, 2.9%, and 6.0%, respectively. Multivariable regression analyses including covariates revealed that individuals with CUS duration 1 < to 2 h had a significantly decreased risk of depression compared to individuals with CUS duration ≤0 h (odds ratio [OR] = 0.517, 95% CI = 0.309–0.865). Individuals with CUS duration 0 < to 1 h (OR = 0.731, 95% CI = 0.505–1.060) and >2 h (OR = 1.164, 95% CI = 0.718–1.886) showed no significantly different risk of depression.ConclusionsThe risk of depression in individuals with CUS duration 1 < to 2 h was lower than for those with CUS duration ≤0 h. This finding provides a better understanding on the association between CUS and depression; and can be a basis for better management of depression.     

基于PBL的SPSS软件的教法与学法

提出基于PBL的教与学过程中需要注意的几个原则,包括充分利用软件的窗口界面优势、注意统计分析前的数据管理、注意各类推断统计分析使用条件的审定,例题选取由简入难,由浅入深、注意挖掘已有文献的示范作用、及时总结答疑等。     

SPSS正交设计在福建金线莲组织培养中的应用

目的：研究植物激素对福建金线莲茎尖与茎段生长及分化的影响。方法：选用福建金线莲的茎尖与茎段为材料，采用SPSS正交设计研究6-苄基腺嘌呤(6-BA)、萘乙酸(NAA)对茎尖的叶片数、茎节数、侧枝数、株高，茎段的侧枝数、茎节数等的影响，并用SPSS进行数据处理。结果与结论：首次报道了NAA对福建金线莲的促生长作用在低浓度(<1 mg·L^-1)和高浓度(>1 mg·L^-1)时各不相同。MS+NAA 0.5 mg·L^-1+6-BA 1 mg·L^-1最适宜福建金线莲茎尖的生长；MS+NAA 1 mg·L^-1+6-BA 2 mg·L^-1最适宜茎尖与茎段芽分化及侧枝形成。NAA与6-BA的不同浓度水平组合，对福建金线莲茎尖与茎段生长及分化的影响不同，两激素间存在着较强的交互效应。     

Investigation of COVID-19 fear,treatment compliance,and metabolic control of patients with type 2 diabetes mellitus during the pandemic

AimsThis study was carried out to investigate fear levels, treatment compliance, and metabolic control of type II Diabetes Mellitus patients during the COVID-19 pandemic.MethodsThe study employed a single-center, observational design and was conducted between January and April 2021. The study consisted of 303 patients who attended the internal medicine outpatient clinic of a university hospital in Turkey. For data collection, the Patient Identification Form, COVID-19 Fear Scale, and the Type II Diabetes Treatment Compliance Scale were used. The study complied with the Helsinki Declaration criteria. IBM SPSS v25.0 statistics package program was used for data analysis.ResultsThe mean age of the patients was 45.8 ± 7.5 years, the mean duration of illness was 8.2 ± 3.6 years. Moreover, 40.6% of patients presented with poor levels of treatment compliance. In addition, the mean FCV-19S score of the patients was 29.1 ± 3.05. It was noticeable that those with high mean scores of FCV-19S had poor compliance with treatment and metabolic control during the pandemic (p < 0.05).Practice implicationsFear of COVID-19 negatively affects treatment compliance and metabolic control of type II diabetes patients. The patients avoided attending their regular follow-ups at the hospital due to fear of contracting COVID-19. In order to reduce the fear of COVID-19 it is paramount to maintain optimum metabolic control and treatment compliance.     

曲线拟合用于4台血细胞分析仪之间的非线性比对研究

目的利用非线性过程对不同血细胞分析仪之间的结果进行比对研究。方法每天收集5份高、中、低不同浓度水平的病人血液样本,每份样本分别使用Bayer120、CD3500、BC5500和BC3000血细胞分析仪进行测定,利用SPSS曲线拟合（Curve Estimation）程序的11种回归模型（包括线性模型）对不同仪器WBC,RBC和HGB项目的测定结果进行拟合。结果所选出的最佳模型的决定系数值均大于0．981（相关系数大于0．990）,这使血细胞分析仪之间的方法比对和偏差估计更为准确可靠,且可比对范围更广。结论非线性比对适用于临床检验的方法比对和偏差估计。