肛欣冲剂治疗肛肠疾病80例疗效观察

目的:观察肛欣冲剂熏洗治疗肛肠疾病的临床疗效。方法:将肛肠病患者120例随机分为2组。治疗组80例应用肛欣冲剂(由马齿苋、五倍子、蛤蟆草、枳壳、芒硝、冰片等组成)治疗,对照组40例用复方荆芥熏洗剂治疗。2组均以10天为1疗程。结果:治疗组临床治愈43例,显效24例,有效7例,无效6例,总有效率92.5％。对照组临床治愈15例,显效11例,有效5例,无效9例,总有效率77.5％,2组总有效率比较,差异有显著性意义(P<0.05),提示治疗组疗效优于对照组。结论:肛欣冲剂在改善肛门疼麻肿胀、下坠、便血、肛门潮湿等常见症状方面,优于复方荆芥熏洗剂。     

推拿结合中药熏洗治疗髌下脂肪垫损伤79例

运用推拿结合中药熏洗治疗髌下脂肪垫损伤79例。疗程14～21日。结果：治愈29例，显效35例，好转12例，无效3例；总有效率达96．2％。     

Herbal hepatotoxicity: Analysis of cases with initially reported positive re-exposure tests

BackgroundPositive re-exposure tests are diagnostic hallmarks for hepatotoxicity.ObjectiveTo test validity of positive re-exposures in herb induced liver injury.MethodsWe searched Medline database for cases of herb induced liver injury with positive re-exposures and analysed 34 cases for positive re-exposure test criteria of baseline alanine aminotransferase < 5N before re-exposure, and re-exposure alanine aminotransferase ≥ 2× baseline alanine aminotransferase. Re-exposure test was negative, if baseline alanine aminotransferase < 5N combined with re-exposure alanine aminotransferase < 2× baseline alanine aminotransferase, or if baseline alanine aminotransferase ≥ 5N regardless of the re-exposure alanine aminotransferase including no available re-exposure alanine aminotransferase result.ResultsIn 21/34 cases (61.8%), criteria for a positive re-exposure were fulfilled, with negative tests in 6/34 cases (17.6%) or uninterpretable ones in 7/34 cases (20.6%). Confirmed positive re-exposure tests established potential of herb induced liver injury for Aloe, Chaparral, Chinese herbal mixtures, Chinese Jin Bu Huan, Chinese Syo Saiko To, Germander, Greater Celandine, Green tea, Kava, Mistletoe, Polygonum multiflorum, and Senna, with up to 4 case reports per herb.ConclusionsAmong 34 cases of herb-induced liver injury with initially reported positive re-exposure tests, 61.8% of the cases actually fulfilled established test criteria and provided firm diagnoses of herb induced liver injury by various herbs.     

A systematic review of the efficacy and safety of Rosa damascena Mill. with an overview on its phytopharmacological properties

Rosa damascena Mill. is one of the most famous ornamental plants cultivated all over the world mostly for perfumery industries. Traditionally it has been used as an astringent, analgesic, cardiac and intestinal tonic.The paucity ofauthoritative monographs urged usto summarize its clinical effectiveness and safety with acomprehensive review of the literature.“PUBMED”, “SCOPUS”, “WEBOF SCIENCE” were searched up to April 30, 2017 with search terms:(“Rosa damascena” OR “Damask Rose”). All human studies with any mono-preparation were included. In vitro and animal studies from “PUBMED”were also reviewed and outlined.Of “1000” identified publications, twelveeligibleclinical trials were retrieved. Antimicrobial, anti-inflammatory, antioxidant, anticancer, protective neuronal, cardiac, gastrointestinal and hepatic effectsin 30 in vitro and 21 animal studies were also shown. there are promising evidences for the effectiveness and safety of Rosa damascena Mill in pain relief, but confirmatory studies withstandardized products is suggested.     

穴位按摩配合中药熏洗治疗中风半身不遂的效果观察及护理

目的：探讨穴位按摩配合中药熏洗治疗中风半身不遂的临床效果。方法将中风后半身不遂的患者84例分为两组，对照组采样常规治疗；观察组在常规治疗的基础上，采用中药熏洗配合穴位按摩治疗，2个疗程后对患者肌力、关节活动度进行对比。结果观察组肌力改善总有效率为83．3％，关节活动度改善总有效率77．15％，对照组肌力改善总有效率为58．3％，关节活动度改善总有效率55．5％，两组比较差异有显著意义（ P＜0．05）。结论穴位按摩配合中药熏洗治疗中风病半身不遂临床效果优于单纯的药物治疗。     

手法复位加中药熏洗治疗旋前外展型踝关节骨折效果探讨

目的：分析研究手法复位加中药熏洗治疗旋前外展型踝关节骨折的临床应用价值。方法：选取2008年8月至2012年8月在该院接收的旋前外展型踝关节骨折患者一共有56例，对56例患者采取手法复位加中药熏洗治疗，对其临床治疗效果给予分析。结果：56例患者，其中优43例（76.79％）；良10例（17.86％）；差3例（5.36％），优良率为94.64％，临床手术以后跟踪随访6个月～3年，病人全部治愈。结论：旋前外展型踝关节骨折采取手法复位加中药熏洗治疗，可以使相关症状得到明显改善，使临床治疗效果进一步提高，具有临床推广价值。     

熏洗治疗的研究进展

熏洗疗法是传统中医外治法的重要组成部分,是根据中医辩证论治方法,选择适宜中药煎煮,或熏蒸,或洗浴全身、局部治疗疾病的方法。熏洗疗法具有温经散寒、行气活血、祛风除湿、清热解毒等作用,可用于治疗临床大多数疾病,近年来随着对透皮技术及自动化熏洗仪的研究,与现代科技相结合的熏洗技术已不同于几千年前,疗效也获得越来越多的肯定,现将近年来中药熏洗疗法的研究概况综述如下。     

基于QbD理念的肿节风分散片制备工艺的优化

基于质量源于设计(QbD)理念,应用鱼骨图、失效模型与影响分析模型筛选了可能影响分散片质量的风险因素。继而采用Plackett-Burman设计,以片剂的分散均匀性(崩解时间)、花斑率及颗粒成型性为评价指标筛选有显著性影响的处方因素,再运用中心点复合设计-响应面法优化肿节风分散片的处方配比,建立工艺设计空间并进行验证。结果显示,崩解剂用量、润滑剂用量及黏合剂用量因素是影响试验结果的3个关键处方因素,所得优化处方为:崩解剂(交联聚乙烯吡咯烷酮)用量占处方量15.5%,润滑剂(硬脂酸镁)占处方量的0.4%,黏合剂(85%乙醇)用量为干浸膏粉2.5倍量,按此处方制备肿节风分散片,崩解时间小于45 s,花斑率低于10%。本试验表明,基于QbD理念对肿节风分散片的处方进行优化是可行的,设计空间范围内制备的分散片符合要求且外观较好,可为其大生产提供参考。     

中药熏蒸结合悬吊运动疗法治疗膝骨性关节炎的疗效观察

目的：观察中药熏蒸结合悬吊运动疗法治疗膝骨性关节炎的临床疗效。方法将30例膝骨性关节炎患者随机分为观察组和对照组各15例;观察组采用中药熏蒸结合悬吊运动疗法进行治疗,对照组采用中药熏蒸结合常规康复训练的方法,每组均治疗1个月。分别于治疗前和治疗1个月后对患者进行膝关节功能评定（Lequesne指数）和疗效观察。结果两组患者治疗后的膝关节功能评分及疗效观察较治疗前均有改善,而观察组显著优于对照组。结论中药熏蒸结合悬吊运动疗法能更有效的改善膝骨性关节炎患者的膝关节功能,且治疗效果显著,两者结合具有协同作用。     

电针结合中药熏蒸治疗早期髌股关节炎的临床观察

目的:观察电针结合中药熏蒸治疗早期髌股关节炎的临床疗效。方法:将56例早期髌股关节炎患者随机分为治疗组与对照组各28例。治疗组采用电针结合中药熏蒸治疗;对照组单纯采用电针治疗。比较2组治疗前后骨性关节炎指数(WOMAC)评分并评定疗效。结果:2组患者治疗后WOMAC各项评分(疼痛评分、僵硬评分、日常活动功能评分及总评分)均明显降低,与同组治疗前比较,差异均具有统计学意义(P0.01),且治疗组WOMAC各项评分改善优于对照组,差异具有统计学意义(P0.05)。治疗组总有效率为96.43%,对照组为85.71%,2组比较差异具有统计学意义(P0.05)。结论:电针结合中药熏蒸治疗和单纯电针治疗早期髌股关节炎疗效确切,且电针结合中药熏蒸治疗优于单纯电针治疗。