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1.
Effect of 1,25(OH)_2D_3 on the growth and apoptosis of breast cancer cell line MCF-7 总被引:1,自引:0,他引:1
Thesteroidhormone 1,2 5 dihydroxyvitaminD3 (1,2 5(OH) 2 D3 )isbiologicallythemostactiveformofvitaminD3 andplaysanimportantroleintheregulationofcalciumandbonemetabolism Theeffectsof1,2 5(OH) 2 D3 aremediatedbyvitaminDreceptors (VDR)intargettissues Inthelastdecade,VDRwasno… 相似文献
2.
INTRODUCTION Chinahasgotgreatachievementsinleprosycontrolwiththeimplementationofmultidrugtherapy (MDT)inthewholecountry .Inordertosolvetheleprosyproblemscompletely ,ChinesegovernmentnotonlyfocusesoncasefindingandMDT ,butalsopreventionofdisability (POD)and… 相似文献
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INTRODUCTIONDisabilityAdjustedLifeYear(DALY)isanewmeasurementofburdenofdisease(BOD)introducedbyC.Murrayandhiscolleagues(Murray,1994;MurrayandLopez,1994).ThismeasurementconsistsofYearsofLifeLost(YLL)andYearsLivedwithDisability(YLD).DALYismorereasonableandcomprehe… 相似文献
4.
Dilatedcardiomyopathy(DCM)andischemiccardiomyopathy(CADCM)mayhavesimilarclinicalpresentations,suchascardiomegaly,impairedleftventricularfunctionandcongestiveheartfailureThedifferentiationofDCMfromCADCMsometimesisdifficultbutimportant,sinceprognosisandtr… 相似文献
5.
Dendriticcells (DCs)havedrawnwideattentioninrecentyears ,becausetheyarethemostefficientantigen presentingcells (APC)intheactivationofnaiveTcellsofbothCD4 andCD8 types ThisabilityofDCstopresentantigenstoTcellsandtoinitiateimmuneresponseshasbeensuccessfullyu… 相似文献
6.
Vitamin D receptor gene polymorphism in postmenopausal women of the Han and Uygur nationalities in China 总被引:2,自引:0,他引:2
Theriskofosteoporosisiscloselyrelatedtobonemineraldensity (BMD ) ,whichisunderstronggeneticcontrol Morrisonetal1 haveshownastrongrelationshipbetweenpolymorphismatthevitaminDreceptor (VDR)geneandBMD InadditiontoBsmⅠ ,restrictionfragmentlengthpolymorphismatth… 相似文献
7.
Pulmonary embolism associated with nephrotic syndrome in children: a preliminary report of 8 cases 总被引:5,自引:0,他引:5
Hypercoagulationandthromboembolismwerecommoncomplicationsinnephroticsyndrome (NS) .1 However ,pulmonaryembolism (PE )inNSchildrenisseldomreported.Herewereported 8outof 2 0NSchildrenwithelevatedplasmaD dimerinwhomPEwasdiscoveredbypulmonaryperfusionimaging (PPI) .… 相似文献
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INTRODUCTIONVascularendothelialgrowthfactor (VEGF)receptorFlt 1isakindofglucoproteinwithamolecularweightof 1 80KD .Asafamilymemberoftyrosineproteinkinasereceptorsub typeⅢ ,itconsistsofextracellular,transmembraneandintracellulardomains.TherearesevenIg likeloop… 相似文献
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Purpose Toreviewthepathogenesis ,clinicalpresentation ,diagnosticassessmentandtreatmentregimensofsteroid inducedboneloss .Datasources AnEnglish languageliteraturesearch(MEDLINE 1966- 1999)andbibliographicreviewsoftextbooksandreviewarticles .Studyselection Cross … 相似文献
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Theeukaryoticcellcycleiscontrolledbyproteincomplexescomposedofcyclinsandcyclin dependentkinases(CDK)andtheactivityofCDKisregulatedbyassociation dissociationwithcyclin dependentkinaseinhibitors(CDKI) 1 Twofamilies (p16andp2 1)oftheseinhibitorshavebeenidentifi… 相似文献
11.
Relationship Between CD44v6 Expression and Metastatic Potential and Prognosis in Gastric Carcinoma 总被引:2,自引:0,他引:2
AnalysisofthesignificanceofCD4 4geneproductex pressionforcancerdiagnosishasrevealedthathumantumorsfromthebreast,colon ,andthyroidexpressmanyalternativespliceCD4 4geneproducts.Theaimofthisstudyistoin vestigatetheexpressionofCD4 4splicevariant 6 (CD4 4v6 )ingastri… 相似文献
12.
Thepublichealthworkershavelongedforanidealmethodtoevaluatepeople′sdietarypatterns,whichcanbeusedtoanalyzethedi etarypatterngrosslyandcomprehensivelyus ingrathersimplecalculations,yetmustbeeasyforthemassestounderstand .Thedesireddietarypattern (DDP) ,propo… 相似文献
13.
Lowplasmahighdensitylipoproteincholesterol(HDLC)anditsconstituentapolipoproteins(apoAIandapoAII)levelshavebeenfoundtobeindependentriskfactorsforcoronaryheartdisease(CHD)inseveralstudiesandhigherconcentrationsofHDLCandtheconstituentapolipoproteinsofferpr… 相似文献
14.
皮质发育障碍与癫痫发作 总被引:13,自引:8,他引:5
皮质发育障碍 (disordersofcorticaldevelopment,DCDs) ,又称作皮质发育不良 (corticaldysplasias)、皮质发育畸形 (malfor mationofcorticaldevelopment,MCD)、灰质异位症、神经元移位症 (neuronalmigrationdisorders,NMD)等。近两年来在癫痫的病因诊断中DCDs迅速占领了中心位置。这是因为在过去的10年中 ,我们对脑发育紊乱及其基因调控、临床表现和DCDs致痫机制等方面取得了令人鼓舞的进展。1 分 类… 相似文献
15.
Wei-Bo Lu 《中国结合医学杂志》2001,7(3):227-228
·Source “FormulariesoftheBureauofPeople’sWelfarePharmacies” ,compiledbyChenShi wen (陈师文 )etal.,inSongDynasty ,in 115 1A .D .,in 10volumes ,788recipes ,mostofwhichwerepillandpowderform ,readyforuseandstorage .Carriedin “HeilongjiangDrugStandard”(1980 )·ChiefIngredients Rhi… 相似文献
16.
LE Wei-dong 《南京医科大学学报(自然科学版)》2002,16(1)
Parkinson′sdisease (PD)isaneurodegenera tivedisordermanifestedclinicallybytremor,slow nessofmovement,increasedmuscletone ,andpos turalinstability ,andpathologicallybyselectivelossofdopaminergic (DAergic)neuronsinthesub stantianigra[1,2 ] .Althoughthecauseofthedi… 相似文献
17.
INTRODUCTION CD9antigen(Ag)isa 2 4 kDmembraneglycoproteinexpressedonthesurfaceofhumanplateletsaswellasonthesurfaceoflymphoidprogenitorcells ,pre Bcellleukemiaandothercelltypes.Thisproteinbelongstoarecentlydelin eatedfamilyofcell surfaceAgsthatspanthemembra… 相似文献
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INTRODUCTION Natriureticpeptideisafamilyofhormoneinvolvedintheregulationoffluidbalance .Atrialnatriureticpeptide(ANP)andbrainnatriureticpeptide(BNP)aretwomembersofthisfamilywhichhadbeenseparatedfromatriaandbrain .C typenatriureticpeptide (CNP)isthenewlyid… 相似文献
19.
Dendriticcells (DCs)arethemostpowerfulantigen presentingcells (APCs) DCshavetheuniquecapacitytostimulatenaiveTcellstoinduceanantigen specificprimaryimmuneresponse ,whereasotherAPCscanonlyactivatealreadystimulatedTcells 1 Atthistime ,themechanismunderlyingth… 相似文献
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INTRODUCTION Graves’disease(GD)isoneoftheautoimmunethyroiddiseases(AITD) ,andischaracterizedbyhypermetabolicandhyperthyroidsyndromecausedbyTSHreceptor stimulatingantibody TheetiologyandpathogenesisofGDarestillnotfullyclarified TheroleofTcellswaswidelyst… 相似文献