导电炭黑填充室温硫化硅橡胶的屏蔽性能

研究了导电炭黑及镍粉等导电填料填充室温硫化(RTV)硅橡胶的电阻率及屏蔽值随填料配比、拉力的变化特性。结果表明,在低阻值情况下可用Schelkunoff理论较好地描述其屏蔽效果,且屏蔽值随着电阻值的变化产生了类似于渗滤现象的突变;在102Ω·cm以下随着电阻率的降低,屏蔽效果迅速增加。同时根据隧道导电理论推导了电阻值随拉力的变化关系,该关系式可近似用二次多项式表示,并对实验结果进行很好地拟合。     

不稳定膀胱误诊1例

患者 ,女性 ,4 0岁 ,因“体检发现下腹部肿块 1 0余天”收入院。既往患有糖尿病史 1 0余年 ,尿频、尿失禁 3年。体检 :发育正常 ,营养中等。淋巴结 (- ) ,心肺 (- ) ,下腹部稍胀 ,可触及 1 0cm× 8cm大小肿块 ,质软 ,无压痛 ,不活动。B超示 :子宫体偏右方可探及一约 1 0 .8cm× 8.2cm的液性回声区 ,包膜完整 ,内透声好 ,双肾大小形态可 ,内回声均质 ,集合系统均光点分离 (右 5 .3cm× 2 .0cm、左 3.9cm× 2 .0cm)。血分析 :HB 1 2 6 g/L ,WBC 5 .6× 1 0 9/L ,RBC3.93× 1 0 12 /L ,N 0 .80 4 ,GLM ,BS 1 3.1mmol/L。诊断 :(1 )卵…     

纤维用耐久性抗静电剂及其性能研究

以烷基酚聚氧乙烯醚甲基丙烯酸酯、甲基丙烯酸缩水甘油酯为原料,通过溶液聚合合成一种纤维用 耐久性抗静电剂。通过正交试验确定了最佳合成工艺条件,并以扫描电镜观察抗静电剂在纤维表面的涂敷效 果。结果表明,抗静电剂能均匀地涂敷在纤维表面。抗静电剂含量为0.6 g／100 g纤维的体积电阻率达到10R Ω·cm,经多次水洗后纤维仍具有较好的抗静电性能(体积电阻率<109Ω·cm)。     

跟骨定量超声与Singh指数评价骨质量

目的 :探索跟骨定量超声 ( QUS)的临床应用价值。方法 :对骨科门诊自愿受试者进行 QUS测值及髋关节 X线摄片 ,由同一名放射专家行 Singh指数分级 ,随机取 48例 QUS主要参数及据 X线评估的 Singh指数 ,采用 SPSS软件作统计学处理 ,分析 QUS主要参数与 Singh指数的相关性 ,并建立判别方程 ,由 QUS的主要参数宽带超声衰减 ( BUA)、劲度指数 ( STI)及超声速率 ( SOS)求出 Singh指数。结果 :QUS主要参数中 ,BUA与Singh指数呈显著正相关 ( r =0 .85 7,P <0 .0 0 1 ) ,STI与 Singh指数呈显著正相关 ( r =0 .80 8,P <0 .0 0 1 ) ,而SOS与 Singh指数无显著相关性 ( r =-0 .2 2 9,P >0 .0 5 )。判别方程为 :F1 ( 1 ) =-2 40 7.3 3 5 +1 0 .999× BUA+3 .0 83× SOS-7.71 5× STI;F2 ( 2 ) =-2 3 99.92 6+1 0 .85 6× BUA+3 .0 78× SOS-7.60 5× STI;F3( 3 ) =-2 3 60 .5 1 2 +1 1 .1 1 7× BUA+3 .0 46× SOS-7.61 8× STI;F4 ( 4 ) =-2 3 3 7.466+1 1 .1 79× BUA+3 .0 2 5× SOS-7.5 1 3× STI;F5( 5 ) =-2 3 1 0 .60 3 +1 1 .2 2 7×BUA+3 .0 0 3× SOS-7.441×STI;F6 ( 6) =-2 3 1 7.5 0 0 +1 1 .2 2 9× BUA+2 .999× SOS-7.3 1 4× STI。结论 :QUS评价骨质量具有量化评估、省时、省钱、无辐射危害等优点 ,     

过碳酸钠的热分解反应动力学

以 Coats和 Redfern线性化简单图解法对加入稳定剂和未加稳定剂的过碳酸钠热分解过程中的动力学特征参数进行了计算。结果表明 ,过碳酸钠热分解的反应级数为 0 .2 ,加入稳定剂与不加稳定剂的样品的活化能分别为 1 83.9k J/mol、1 62 .5k J/mol,频率因子为 2 .1 5× 1 0 2 0 s-1和9.1 2× 1 0 18s-1。由热分解动力学参数可以看出 ,加入稳定剂的产品比不加稳定剂的产品稳定性好     

改性芳纶/聚苯胺复合导电纤维的制备

以聚对苯二甲酰对苯二胺（简称芳纶,PPTA）纤维为基材,使用环氧氯丙烷（ECP）对PPTA表面进行有机修饰,得到了ECP改性的PPTA纤维(ECP-PPTA),然后使苯胺单体在ECP-PPTA表面接枝聚合,制备了ECP-PPTA/PANI复合导电纤维。用傅里叶变换红外分光光度计（FT-IR）、扫描电子显微镜（SEM）、热重分析仪（TGA）及X射线衍射分析仪 (XRD)等分析测试方法对ECP PPTA及ECP-PPTA/PANI复合导电纤维进行了表征。结果表明：PPTA经ECP改性后,PANI成功接枝在PPTA表面,制备的ECP-PPTA/PANI复合导电纤维的电阻率低于PPTA/PANI纤维的,其室温电阻率最低为0.32 MΩ·m。     

高效液相色谱法测定氟康唑软膏的含量

目的 :研究高效液相色谱法测定氟康唑软膏含量的方法。方法 :色谱柱 4× 15 0mm ;流动相为甲醇 -水 (5 0∶5 0 ) ;检测波长为 2 6 1nm ;流速为恒速 1ml·min-1。结果 :氟康唑软膏在 0 0 6～ 0 30mg·ml-1线性范围关系良好。得回归方程为C =7 2 95× 10 -7A +1 76× 10 -2 ,γ =0 9998,回收率为 99 6 % ,RSD =0 73%。结论 :方法快速、准确 ,可作为本品的质控标准。     

降钙素对成骨细胞作用机制的体外实验研究

目的　观察降钙素 (calcitonin ,CT)对体外培养成骨细胞功能及其细胞因子表达的影响 ,初步探讨其作用机制。方法　采用酶消化法培养新生SD大鼠的成骨细胞 (osteoblast,OB) ,加入不同浓度 (1× 10 -12 ～ 1× 10 -8mol/L)的CT ,观察OB的增殖、分化功能和矿化功能。采用RT PCR方法观察胰岛素样生长因子Ⅰ(IGF Ⅰ )、碱性磷酸酶 (ALP)的表达。结果　增殖率测定CT组自 1× 10 -12 mol/L起 ,吸光度 (A值 )均较对照组增加 ,且呈剂量依赖关系 ,CT≥ 1× 10 -9mol/L时差异有显著性 (P =0 .0 39) ;ALP活性自 1× 10 -12 mol/L起均较对照组增加 ,也呈剂量依赖关系。CT≥ 1× 10 -10 mol/L时差异有显著性 (P =0 .0 32 ) ;矿化结节面积 /孔 :CT=1× 10 -12 mol/L组为对照组的 1.6 72倍 (P =0 .0 2 4 ) ,1× 10 -8mol/L组为对照组的 2 .92 4倍 (P =0 .0 0 6 )。CT组细胞因子IGF Ⅰ、ALPmRNA表达较对照组显著升高 (P <0 .0 5 )。结论　适当浓度的CT对体外培养的OB增殖、分化、矿化均具有促进作用。部分机制与CT可以刺激IGF Ⅰ表达增加有关。     

肿瘤放疗楔形照射野深度和射野大小对楔形因子的影响

目的 :探讨楔形野深度和射野大小对楔形因子的影响。方法 :利用电离室法分别测量 15°、30°、 4 5°和 60°楔形板在 1 5cm、 5 0cm、 10 0cm和 15 0cm深度处的 5cm× 5cm、 10cm× 10cm、15cm× 15cm和 2 0cm× 2 0cm 4种照射野的楔形因子。结果 :深度对楔形因子的影响较为明显。深度增加时楔形因子增大 ,且楔形板角度增大时深度对楔形因子的影响增大。对 10cm× 10cm照射野 ,在深度由 1 5cm增加到 15 0cm时 ,15°～ 60°楔形因子分别增加了 1 9%、 3 4 %、 4 9%和 6 1% ;射野大小对楔形因子也有一定影响。在 5 0cm深度处 ,4种楔形野当射野由 5cm×5cm增加到 2 0cm× 2 0cm时 ,楔形因子分别增大了 0 6%、 1 6%、 1 1%和 0 8%。结论 :临床剂量计算时 ,深度对楔形因子的影响应予以修正 ,建议采用相对深度楔形因子 ;射野大小对楔形因子的影响较小 ,可以忽略     

卵巢及乙状结肠放线菌病超声表现1例报告

1临床资料患者,女,41岁,已婚。腹痛3个月,近1个月加重入院。查体:左附件区可触及6cm×6cm×7cm肿物,实性不活动,有压痛。超声检查:子宫前位5·6cm×5·5cm×4·0cm,回声均匀,左附件区可见5·7cm×6·5cm×4·6cm实性不均匀团块,轮廓不规整,边界尚清。膀胱局限性增厚,范围5·0cm×2·4cm(图1)。彩色多普勒:肿块及增厚的膀胱壁上见较丰富血流信号(图2),肿块内最大血流速度39·0cm/S,最小血流速度13·0cm/S,阻力指数0·67。超声诊断:(1)左附件区实性肿物;(2)膀胱壁局限性增厚。术中所见:子宫正常大,左附件与乙状结肠粘连成团,乙状结肠及其系膜…     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…