周口地区2655例成人空腹血脂水平分析

目的:通过检测健康体检者空腹血脂水平来了解周口地区人群血脂水甲现状及其血脂异常患病率.方法:应用日立7170A全自动生化分析仪检测周口地区2655例成人空腹血脂,包括甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和低密度值蛋白胆固醇(LDL-C),比较不同性别和年龄组间血脂水平差别及血脂异常患病率的差异.结果:总体血脂异常患病率65.9%,男性76.3%,女性47.2%.男性和女性4种血质成分异常患病率均随年龄增加而增高(P<0.01).TC、LDL-C、TG水平随年龄的增加而增高(P<0.01),HDL-C水平随年龄的增加有降低趋势(P<0.01).TC在25～44岁间男性高于女性(P<0.01),在55岁以上女性显著高于男性(P<0.05).LDL-C在18～44岁间男性高于女性(P<0.01),在45～74岁女性显著高于男性(P<0.01).HDLC水平各年龄组女性明显高于男性(P<0.01).TG在18～54岁组男性显著高于女性(P<0.01),在55～64岁组两性间无差异,64岁以上女性高于男性(P<0.01).结论:周口地区成人血脂异常患病率较高,并且随年龄增大而增高,男女性别间血脂异常患病率差异有统计学意义.     

吸烟对血脂的影响

目的:探讨吸烟对血中总胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)的影响.方法:2008名健康体检者就吸烟与不吸烟分为两组,经协方差分析,比较两组间血脂指标的差异.结果:吸烟组TG增高(P=0.003),HDL-C(P＜0.0001)降低;TC/HDL-C、LDL-C/HDL-C的比值也显著升高(P＜0.0001,P=0.0003);随吸烟程度加重TC、TG、LDL-C呈现增高趋势,而HDL-C则呈现降低趋势;戒烟后TG显著降低(P＜0.05),而HDL-C升高(P＜0.001).结论:吸烟是脂代谢指标的独立影响因素,戒烟对改善血脂异常有积极意义.     

商丘市职业人群空腹血脂水平分析

目的：探讨商丘市职业人群血脂水平现状及其血脂代谢异常发生率。方法：应用OLYMPUS AU640全自动生化分析仪检测商丘市26 856例职业人群空腹血脂水平,包括总胆固醇（TC）、三酰甘油（TG）、高密度脂蛋白胆固醇（HDL-C）和低密度脂蛋白胆固醇（LDL-C）,并按照血脂异常评定标准分析人群检测结果。结果：总体血脂水平随年龄增长而增高,40～50岁组检出率最高。总体血脂异常发生率为61.2%。男性占73.8%、女性占48.2%。TC、TG、LDL-C水平随年龄增长而增高（P＜0.01）,HDL-C水平随年龄的增长而降低（P＜0.01）。结论：商丘市职业人群血脂异常发生率较高。高血脂检出率随年龄增长而增高,中年以男性、老年女性最为显著。男性与女性血脂代谢异常发生率存在明显差异。     

不同性别早发冠心病患者临床危险因素对比分析

目的 比较不同性别早发冠心病(PCAD)患者临床危险因素的差异,并探讨其意义.方法 选取经冠状动脉造影确诊的PCAD患者270例,分为男性组(158例)和女性组(112例),采集两组患者常见心血管危险因素(高血压、糖尿病、高脂血症、早发冠心病家族史、吸烟、BMI等)和血液指标(血脂、纤维蛋白原、C反应蛋白等),并作对比分析.结果 两组间高血压、糖尿病、早发冠心病家族史、肥胖、血脂异常的差异均无统计学意义(均P ＞0.05),男性组吸烟比例显著高于女性组(P＜0.01),男性组血HDL-C和载脂蛋白a(Apoa)水平显著低于女性组(P＜0.01).结论 男性吸烟和血脂紊乱比例高于女性,提示吸烟和血脂紊乱是男性PCAD患者发病时间提前的重要危险因素,HDL-C和Apoa水平下降可导致冠状动脉保护机制降低.     

鸡西地区从业及退休人员空腹血脂水平分析

目的:通过检查健康体检者空腹血脂水平来分析本地区人群血脂水平及血脂异常患病率。方法:检测鸡西地区4972例成人忌食后空腹血胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平,比较不同性别的年龄组间血脂差异和血脂异常患病率的差异。结果:总体血脂异常率61.2%,男性:73.4%,女性47.8%。男性TC平均4.91mmol/L±0.89mmol/L、HDL-C平均1.22mmol/L±0.31mmol/L、LDL-C平均3.34mmol/L±0.86mmol/L、TG中位数1.47mmol/L;女性TC平均4.73mmol/L±0.91mmol/L、TG中位数0.92mmol/L。TC、TG、LDL-C随年龄增长而增高(P<0.01):HDL-C水平随年龄增长而减低(P<0.01);TC在25岁～44岁男性高于女性(P<0.05),55岁以上女性显著高于男性(P<0.05):LDL-C在25岁～44岁间男性明显高于女性(P<0.01);TG在25岁～54岁男性明显高于女性(P<0.01),55岁以上无显著差异(P>0.05)。结论:鸡西地区成人中血脂异常患病率较高,并随年龄增长而增高,男女性别问血脂异常患异有统计学意义。     

2008年周口地区部分职业人群血脂水平分析

目的:通过检测健康体检者空腹血脂水平来了解周口地区人群血脂水平现状及其血脂异常忠病率.方法:应用日立7170A全自动后化分析仪检测周口公安系统1158例成人空腹血脂包括甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆同醇(LDL-C),比较不同性别和年龄组间血脂水平差别及血脂异常患病率的差异.结果:总体血脂异常患病率59.1%(684/1158),男性63.3%(580/916),女性43.0%(104/242).男性TC平均(4.80±0.95)mlnol/L,HDL-C平均(1.32±0.24)mmol/L、LDL-C平均(2.76±0.77)mmol/L、TG平均(1.59±1.00)mmol/L:女性TC平均(4.65±1.00)mmol/L、HDL-C平均(1.42±0.19)mmol/L、LDL-C平均(2.67±0.80)mmol/L、TG平均(1.25±0.77)mmol/L.男性和女性四种血脂成分异常患病率均随年龄增加而增高.TC、TG、LDL-C水平随年龄增加而增高,HDL-C水平随年龄增加有降低趋势.结论:周口地区成人中血脂异常患瘸率较高,并且随年龄增大而增高,男女性别间血脂异常患病率差异有统计学意义.     

Investigation and analysis of empty Stomach lipid level of middle-aged people in Shenzhen

目的 了解深圳市中年体检人群血脂水平的现状,为血脂异常防治工作提供科学依据.方法 选择1604例来我院特诊门诊进行高级体检的中年人群,采用酶法-终点法检测其空腹血脂水平,并进行统计学描述,比较男、女间血脂异常患病率的差异及不同年龄、性别间的血脂水平差别.结果 1)血脂异常的总患病率为45.18%,男性为47.71%,女性为40.16%,男、女性间血脂异常患病率差异有统计学意义(P＜0.001);血总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)患病率分别为60.97%、45.01%、26.31%、48.44%;2)男、女性间TG、HDL-C异常患病率差异有统计学意义(P＜0.001);3)TC、TG、LDL-C、HDL-C总体水平分别为(5.52±0.81)、(2.09±1.85)、(3.19±0.58)、(1.04±0.18).结论 深圳市中年体检人群血脂异常患病率甚高,尤以TC、HDL-C异常患病率增高明显,应关注这一人群的健康教育及干预,采取针对性的有效措施,改善血脂水平,最大限度地预防心血管疾病的发生.     

某中医院校在职教职工脂肪肝与血脂水平的相关性研究

目的 了解某中医院校在职教职工脂肪肝发生率和血脂各指标水平,探讨脂肪肝与血脂各指标水平的相关性。方法 选择某中医院校参加2015年健康体检的715名在职教职工为研究对象,进行体格测量、血脂检测和腹部彩超检查。结果 715名教职工脂肪肝检出率为19.86%,其中轻度和中度检出率分别为17.34%和2.52%,不同性别和年龄教职工脂肪肝检出率间差异具有统计学意义(P＜0.05)。随脂肪肝病情加重总胆固醇(TC)、甘油三酯(TG)和低密度脂蛋白(LDL-C)水平增加而高密度脂蛋白(HDL-C)水平逐渐下降,男性不同程度脂肪肝教职工TG和HDL-C间差异具有统计学意义(P＜0.05),女性不同程度脂肪肝教职工血脂各指标间差异具有统计学意义(P＜0.05)。脂肪肝病情与TC、TG和LDL-C水平呈正相关(P＜0.05),与HDL-C水平呈负相关(P＜0.05)。142名脂肪肝教职工血脂异常检出率为59.86%,其中轻度和中度脂肪肝者血脂异常检出率分别为57.26%和77.78%,与非脂肪肝比较差异具有统计学意义(P＜0.05);男性不同程度脂肪肝教职工TC、TG和HDL-C异常检出率间存在显著差异(P＜0.05),女性不同程度脂肪肝教职工血脂各指标异常检出率间差异具有统计学意义(P＜0.05)。logistic回归分析表明,TC和HDL-C异常是影响男性教职工发生脂肪肝的危险因素,TG和HDL-C异常以及年龄是影响女性教职工发生脂肪肝的危险因素。结论 该校脂肪肝教职工血脂异常检出率较高,脂肪肝与血脂各指标水平具有显著相关性。     

桂林市某医院体检中心成年人血脂异常流行病学调查及其危险因素分析

目的 了解桂林市成年人血脂异常患病情况,并分析其主要的危险因素.方法 对桂林市6 660名成年人进行体格测量、实验室检查和肝脏彩超检查等.结果 6 660名成年人血脂异常患病率为31.8％(男性为40.5％,女性为22.3％),标化后患病率为30.6％(男性为39.9％,女性为27.0％);高TC、高TG、高LDL-C、低HDL-C患病率分别为8.0％、17.0％、13.8％、13.3％;血脂异常患病率以男性40～49岁年龄段最高,呈随年龄的增加患病率先逐渐增加后降低趋势,女性则随着年龄的增加而显著升高.血脂异常组合并高血糖、高血压、超重和(或)肥胖、非酒精性脂肪肝(NAFLD)、高尿酸血症的患病率均高于正常组(P＜0.05).多因素logistic回归分析显示:性别(男)、年龄、体重指数(BMI)、NAFLD、高尿酸血症、高血糖均为血脂异常的危险因素.结论 桂林市成年人血脂异常患病率较高,男性、年龄、BMI、NAFLD、高尿酸血症、高血糖均为血脂异常的危险因素.     

新疆尼勒克县蒙古族居民血压与血脂水平的调查分析

目的 了解新疆尼勒克县蒙古族居民的血压和血脂状况.方法 对随机抽取尼勒克县5个蒙古族聚居村19～79岁居民共349人进行了血压、血脂水平(血总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、载脂蛋白A和载脂蛋白B)的测定和分析.结果 调查对象高血压患病率为28.1%(98/349);血脂异常检出率为14.6%(51/349),其中高TC血症、高TG血症、高LDL-C血症、低HDL-C血症以及低Apo-A血症分别为1.4%(5/349)、5.7%(20/349)、4.9%(17/349)、3.7%(13/349)和0.6%(2/349);以高TG血症为主要类型;与女性相比,男性血脂升高较为明显(P＜0.05);血脂异常患者中,男性血脂TG水平较女性显著偏高、LDL-C水平显著偏低(P＜0.01);正常血压组中女性血脂TC、TG水平较高血压组显著偏低(P＜0.05);正常组中女性血脂TG、Apo-B水平较男性显著偏低(P＜0.01).结论 新疆尼勒克县蒙古族居民的高血压、血脂异常患病率仍然较高,血脂水平存在性别差异;高TC、TG血症者高血压患病率增加.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.