某中医院校在职教职工脂肪肝与血脂水平的相关性研究

目的 了解某中医院校在职教职工脂肪肝发生率和血脂各指标水平,探讨脂肪肝与血脂各指标水平的相关性。方法 选择某中医院校参加2015年健康体检的715名在职教职工为研究对象,进行体格测量、血脂检测和腹部彩超检查。结果 715名教职工脂肪肝检出率为19.86%,其中轻度和中度检出率分别为17.34%和2.52%,不同性别和年龄教职工脂肪肝检出率间差异具有统计学意义(P＜0.05)。随脂肪肝病情加重总胆固醇(TC)、甘油三酯(TG)和低密度脂蛋白(LDL-C)水平增加而高密度脂蛋白(HDL-C)水平逐渐下降,男性不同程度脂肪肝教职工TG和HDL-C间差异具有统计学意义(P＜0.05),女性不同程度脂肪肝教职工血脂各指标间差异具有统计学意义(P＜0.05)。脂肪肝病情与TC、TG和LDL-C水平呈正相关(P＜0.05),与HDL-C水平呈负相关(P＜0.05)。142名脂肪肝教职工血脂异常检出率为59.86%,其中轻度和中度脂肪肝者血脂异常检出率分别为57.26%和77.78%,与非脂肪肝比较差异具有统计学意义(P＜0.05);男性不同程度脂肪肝教职工TC、TG和HDL-C异常检出率间存在显著差异(P＜0.05),女性不同程度脂肪肝教职工血脂各指标异常检出率间差异具有统计学意义(P＜0.05)。logistic回归分析表明,TC和HDL-C异常是影响男性教职工发生脂肪肝的危险因素,TG和HDL-C异常以及年龄是影响女性教职工发生脂肪肝的危险因素。结论 该校脂肪肝教职工血脂异常检出率较高,脂肪肝与血脂各指标水平具有显著相关性。

The relativity of fatty liver and serum lipid level among in-service staff in a traditional Chinese medicine college

Objective To know the incidence of fatty liver and the level of blood lipid indexes among in-service staff in a traditional Chinese medicine(TCM) college,and explore the relativity of fatty liver and blood lipid indexes.Methods 715 cases of in-service staff participating in 2015 health examination were selected as research object in a TCM college,the physical measurement was measured,the blood lipid was detected and the abdominal was detected using ultrasonography.Results The detection rate of fatty liver was 19.86% among 715 cases of in-service staff,and the rate of mild and moderate fatty liver was 17.34% and 2.52% respectively,the rate of fatty liver had statistical difference between sex and age(P＜0.05).The level of total cholesterol(TC),triglyceride(TG) and low-density lipoprotein cholesterol(LDL-C) increased gradually while the level of high-density lipoprotein cholesterol(HDL-C)decreased gradually with the aggravation of the fatty liver,the level of TG and HDL-C had statistical difference among different degree of fatty liver in the male(P＜0.05) while the blood lipid indexes had statistical difference among different degree of fatty liver in the female(P＜0.05).The condition of fatty liver was positively related with the levels of TC,TG and LDL-C(P＜0.01),while negatively with the level of HDL-C(P＜0.01).The rate of dyslipidemia was 59.86% among the faculty with fatty liver,and rate of dyslipidemia among mild and moderate fatty liver was 57.26% and 77.78% respectively,there had statistical difference compared with non-fatty liver(P＜0.05); the abnormal rate of TC,TG and HDL-C had statistical difference among different degree of fatty liver in the male(P＜0.05) while the abnormal rate of blood lipid indexes had statistical difference among different degree of fatty liver in the female(P＜0.05).The logistic regression analysis showed that,the abnormity of TC and HDL-C were the risk factors of fatty liver in the male while TG abnormality,HDL-C abnormality and age were the risk factors of fatty liver in the female.Conclusion The rate of dyslipidemia was higher among the faculty with fatty liver in this TCM college,the fatty liver had significant correlation with blood lipid indexes.