终末期肾脏疾病血液透析患者人格特征与生存质量的相关性研究

目的 探讨终末期肾脏疾病血液透析患者生存质量与人格特征的相关性.方法 86例终末期肾脏疾病血液透析患者和89例对照组患者,均使用肾脏疾病生存质量量表(KDQOL-SFTM1.3)、艾森克人格问卷(EPQ)、抑郁自评问卷(SAS)和焦虑自评问卷(SDS)进行调查.结果 EPQ测量中的P因子、N因子、焦虑、抑郁与生存质量呈负相关(0.232＜|r|＜0.827).病例组患者的生存质量低于对照组(P＜0.05).病例组SAS及SDS评分[(50.83±9.46)分,(60.87±11.77)分]显著高于对照组[(46.22±6.61)分,(47.52±7.36)分].结论 终末期肾脏疾病血液透析患者人格中情绪不稳定性高,易产生焦虑和抑郁,生存质量下降.因此,必须把心理治疗和躯体治疗有效结合来提高整体治疗的效果.     

终末期肾病维持性血液透析108例心理状况及生活质量分析

目的:了解血液透析患者的抑郁及焦虑状况,探讨患者心理状况与生活质量的相关性。方法:采用多中心研究方法,对100例血液透析患者采用Zung抑郁自评量表(SDS)、焦虑自评量表(SAS)及终末期肾脏疾病透析患者调查表(KDQOL-SFTM)进行问卷调查。结果:患者SDS均分(54.4±12.29)、SAS均分(53.67±10.7),显著高于国内常模(P<0.01);患者抑郁、焦虑情绪与其生活质量呈明显负相关(P<0.05)。结论:血液透析患者易产生抑郁和焦虑情绪,并影响他们的生活质量,有必要将心理治疗和躯体治疗有效结合来提高整体治疗效果,减少抑郁和焦虑的发生,改善患者的生活质量。     

女性神经性厌食症患者人格特征和心身状况的研究

目的 探讨女性神经性厌食症发病相关的个体人格特征以及心身状态因素.方法 分析23例女性神经性厌食症患者的卡特尔16项人格问卷(16-PF)、90项症状自评量表(SCL-90)、焦虑自评量表(SAS)、抑郁自评量表(SDS)、自我接纳问卷(SAQ)的分值结果 .结果 病例组在16-PF的忧虑性[(6.17±1.40)分]、紧张性[(5.70±1.26)分],SCL-90的强迫症状[(1.56±0.48)分]、人际关系敏感[(1.46±0.40)分]及偏执[(1.32±0.13)分]方面的分值明显高于正常对照组(P＜0.05);同时2组在SAS、SDS分值上差异无显著性;病例组在SAQ总分[(39.87±4.92)分]和自我评价因子分[(20.00±2.61)分]上低于对照组(P＜0.05).结论 女性神经性厌食症患者存在明显的个性缺陷,加强认知治疗可能会对提高治疗效果及预防复发起重要作用.     

心理干预对强直性脊柱炎患者生存质量及心理健康状况的影响

目的探讨心理干预对强直性脊柱炎患者的生存质量及心理健康状况的影响.方法采用病例对照研究方法,测查一般资料、生理指标、健康状况调查问卷(SF-36)、社会支持量表(SSRS)、艾森克个性问卷(EPQ)、医学应对问卷(MCMQ)、抑郁自评量表(SDS)和焦虑自评量表(SAS).对82例强直性脊柱炎患者进行为期1个月的追踪研究,42例常规治疗联合心理干预,40例常规治疗.结果 1.SF-36生存质量影响因素逐步回归结果:影响有性别、受教育程度、家庭人均收入、社会支持、应对方式(回避和屈服)和人格特质.2.①SDS分值具有随治疗时间逐渐下降的趋势[心理干预组:(57.24±8.85)分,(54.71±7.51)分,(54.00±8.10)分;对照组:(57.98±8.11)分,(56.71±7.51)分,(55.00±8.11)分,F=4.501,P＜0.05],心理干预组SDS分较无干预组下降明显(P＜0.05).②SAS分值具有随治疗时间逐渐下降的趋势[心理干预组:(50.10±9.41)分,(48.20±6.82)分,(47.29±7.84)分;对照组:(51.23±10.10)分,(50.10±7.24)分,(48.29±7.38)分,F=1.801,P＜0.05],两组SAS分下降程度类似(P＞0.05).3.治疗前后心理干预组在生理机能、躯体疼痛、精力、情感职能四个方面较无心理干预组改善明显.结论 1.影响强直性脊柱炎患者生存质量因素包括性别、受教育程度、家庭人均收入、社会支持、应对方式(回避和屈服)和人格特质.2.心理干预可以明显缓解强直性脊柱炎患者抑郁情绪和生存质量.     

人文关怀护理对维持性血透患者焦虑抑郁情绪的影响

目的探讨人文关怀护理对维持性血液透析患者焦虑抑郁情绪的影响。方法将广州市红十字会医院血液净化中心收治的92例长期维持性血液透析的患者随机分为试验组和对照组,对照组的患者进行血液透析常规护理,试验组的患者在常规护理的基础上运用人文关怀护理,分别在干预前、后采用焦虑自评量表(SAS)、抑郁自评量表(SDS)对两组患者的焦虑抑郁程度进行评估。结果实施人文关怀护理后,试验组患者SAS、SDS评分分别为(38.92±4.27)、以及(43.72±2.87),对照组患者分别为(60.34±3.12)、(56.14±3.64),实验组患者SAS、SDS评分明显低于对照组,P<0.05,差异具有统计学意义。结论实施人文关怀护理能够改善维持性血液透析患者的焦虑、抑郁状态,提高患者的生存质量。     

抑郁症共病因素及其人格特征的相关与回归分析

目的:探讨有无焦虑症状的抑郁症患者的应付方式与人格的关系.方法:对88例抑郁症患者及与之匹配的90例正常对照组进行抑郁自评量表(SDS), 焦虑自评量表(SAS), 艾森克人格问卷(EPQ)和应付方式问卷评定.结果:与正常对照组相比,抑郁症患者SDS, SAS, EPQ的N, P两个维度的得分高于正常对照组,而EPQ的E维度、积极应付方式得分低于对照组. 有焦虑症状抑郁症患者组相对于无焦虑症状抑郁症患者组,SDS, SAS, EPQ的N, P两个维度的得分明显较高,积极应付方式得分明显较低. 相关、回归分析表明SAS, EPQ的E维度及积极应付方式与抑郁症状严重程度的关系更为密切,这三者可解释抑郁症状严重程度变异的52.0%.结论:抑郁症患者发病期的抑郁症状、焦虑症状、神经质、精神质比对照组明显,这些特征在伴有焦虑症状的抑郁症患者中表现更为明显. 有焦虑症状的抑郁症患者比无焦虑症状的患者人格特征更偏内向,更少采用积极的应付方式. 较少采用积极应付方式可能是抑郁症状患者人格特征之一,纳入人格特质的E维度之中.     

肿瘤患者主观睡眠质量与心身状况相关分析

目的了解肿瘤患者的睡眠质量与焦虑、抑郁情绪等心身状况以及它们之间的关系.方法采用匹茨堡睡眠质量指数量表(PSQI)、焦虑自评量表(SAS)、抑郁自评量表(SDS)、状态-特质焦虑问卷(STAI)和症状自评量表(SCL-90)调查88名肿瘤住院患者主观睡眠质量与心身状况.结果患者在PSQI量表调查中总均分为(6.88±4.08)分,男、女患者分别为(6.47±4.08)分和(7.61±3.97)分,性别间差异无显著性(P＞0.05),PSQI≥8分者占32.4%;SAS与SDS得分分别为(43.5±9.5)分,(44.5±10.8)分.而PSQI得分与SAS、SDS、SCL-90总分间存在显著的相关性(r分别为0.544与0.399,0.493;P＜0.01).结论肿瘤患者的主观睡眠较差,并存在着焦虑及抑郁情绪.睡眠质量与焦虑、抑郁情绪密切相关,PSQI值越高,抑郁及焦虑越严重.     

综合心理干预对乳腺癌患者生存质量的影响

目的 探讨综合性心理干预对乳腺癌患者化疗期间生存质量的影响.方法 将83例化疗期乳腺癌患者随机分为干预组和对照组,干预组除接受常规化疗及护理外还进行为期8周的综合性心理干预,对照组仅接受常规化疗及护理,以乳腺癌患者生命质量测定量表(FACT-B),焦虑自评量表(SAS),抑郁自评量表(SDS )为指标,评价心理干预对乳腺癌患者生存质量的影响.结果 综合性心理干预后干预组总的生存质量以及功能领域和情感领域[分别为(89.49±10.64)分,(15.73±5.50)分,(19.48±5.05)分]明显高于对照组[(分别为(79.68±16.75)分,(12.01±5.81)分,(14.38±4.13)分](P＜0.05),干预后乳腺癌患者的恶心及睡眠状况得到改善(P＜0.05),疼痛程度干预前后变化不明显(P＞0.05);干预后干预组的SAS、SDS评分[分别为(29.03±4.79)分,(30.67±6.12)分]与对照组[分别为(36.15±5.73)分, (42.88±9.45)分]差异具有显著性(P＜0.05).结论 综合性的心理干预能够改善乳腺癌患者的情绪状态,提高其生存质量.     

优质护理干预在胃癌患者围手术期的应用价值

目的观察优质护理干预对胃癌患者负性情绪和术后生活质量的影响。方法将2017年1月至2018年8月沈丘县人民医院收治的84例胃癌患者按照随机数表法分成对照组和观察组,各42例。对照组接受常规护理,观察组接受优质护理干预。使用焦虑自评量表(SAS)和抑郁自评量表(SDS)评估两组患者护理干预前后负性情绪;使用世界卫生组织生存质量测定量表简表(WHOQOL-BREF)评估两组患者出院时的生活质量;比较两组患者护理满意度评分。结果护理干预后观察组患者SAS和SDS评分[(28.94±5.62)分,(24.85±5.57)分]均低于对照组[(40.75±5.59)分,(38.39±5.36)分],差异有统计学意义(均P<0.05);观察组患者出院时WHOQOL-BREF评分[(95.17±5.81)分]高于对照组[(83.26±5.43)分],差异有统计学意义(P<0.05);观察组患者护理满意度评分[(96.21±4.16)分]高于对照组[(86.94±4.63)分],差异有统计学意义(P<0.05)。结论优质护理干预可有效缓解胃癌患者负性情绪,提高患者术后生活质量,具有较高的临床推广价值。     

抑郁症患者生活质量调查及影响因素分析

目的探讨抑郁症患者的生活质量及影响因素。方法采用MOS健康状况调查问卷(SF-36)、汉密顿抑郁量表(HAMD)、副反应量表(TESS)、焦虑自评量表(SAS)、抑郁自评量表(SDS)等对65例抑郁症患者进行评定,并与65名正常健康者进行对照。结果抑郁症患者SF-36评分:生理功能[(69.6±21.6)分]、生理机能[(51.7±34.5)分]、躯体疼痛[(50.8±25.5)]、总体健康[(49.6±22.9)分]、活力[(57.4±18.4)]、社会功能[(59.8±27.4)分]、情感职能[(60.5±36.9)分]及SF-36总分[(58.7±19.8)分]显著低于对照组。家庭支持少、工作能力差的患者生活质量差。多因素逐步回归分析显示,影响患者生活质量的主要因素依次为HAMD、SAS、SDS、TESS。结论抑郁症患者的生活质量全面低下,影响因素是多方面的,应予以重视。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.