肺癌相关肺动脉高压患者临床特点及相关因素分析

目的 通过病例对照研究了解肺癌相关肺动脉高压患者临床特点,并对其相关因素进行分析。方法 随机选取肺癌伴发肺动脉高压患者128例作为病例组,选取128例性别相同、年龄相差3岁以内的肺癌不伴发肺动脉高压患者进行1∶ 1病例对照研究,采用SPSS19.0统计学软件进行单因素和多元Logistic回归分析。结果 两组在临床症状上差异有统计学意义;肺癌伴发肺动脉高压易于发生于腺癌患者（P=0.019）,肿瘤转移患者（68.75% vs 45.31%）,肺内肿瘤转移患者（39.06% vs 3.91%）;肿瘤淋巴结转移患者（P=0.000）;容易表现出出血倾向（27.34% vs 1.56%）;D-二聚体和纤维蛋白原定量升高;血小板升高（34.38% vs 15.67%）;肺动脉主干内径增宽（24.22±2.59mm vs 20.75±2.09mm）;肺部磨玻璃样改变;对抗癌治疗的效果差。多元Logistic回归分析显示纤维蛋白原定量升高（OR=2.524,95% CI：1.171~5.441,P=0.000）及血小板计数升高（OR=3.21,95% CI：1.509~6.832,P=0.003）是危险因素,而治疗后呼吸困难等临床表现好转（OR=0.038,95% CI：0.014~0.107,P=0.000）是保护因素。结论 肺癌伴发肺动脉高压好发于腺癌、肿瘤细胞转移和淋巴结肿瘤细胞转移患者;易发生出血倾向、D-二聚体升高、纤维蛋白原计量升高、血小板计数升高、右心衰竭、肺部磨玻璃样间质改变。纤维蛋白原定量升高、血小板计数升高是肺癌伴发肺动脉高压的独立危险因素,治疗后呼吸困难好转是保护因素。     

红细胞分布宽度与腺性膀胱炎患者术后3年复发的相关性研究

目的 探讨红细胞分布宽度（RDW）与腺性膀胱炎患者术后3年复发的相关性。方法 连续性选择笔者医院117例腺性膀胱炎手术患者的临床资料,依据患者术后3年复发情况分为两组,分别为复发组（n=24）及未复发组（n=93）,比较两组一般临床资料及实验室指标的差异;再根据RDW中位数水平,分为RDW低值组组（n=61）及RDW高值组组（n=56）,比较两组复发率的差异;采用多因素Logistic回归分析找出复发的独立相关因素。结果 腺性膀胱炎患者术后3年复发组的RDW水平（13.1%±1.8% vs 11.7%±1.1%,P=0.001）显著高于未复发组。RDW高值组组复发率（32.1% vs 9.8%,P=0.003）显著高于RDW低值组组;多因素Logistic回归分析显示RDW （OR=2.120,95% CI：1.322~3.401,P=0.002）、慢性泌尿系炎症史（OR=7.476,95% CI：2.076~26.915,P=0.002）及泌尿系结石史（OR=5.428,95% CI：1.245~23.669,P=0.024）是腺性膀胱炎患者术后3年复发的独立相关因素。结论 RDW水平与腺性膀胱炎患者术后3年复发关系密切,高RDW水平的腺性膀胱炎患者,其术后3年复发的风险增加。     

构建危险因素模型预测前降支近段临界病变患者发生主要心脏不良事件的价值

目的 分析前降支近段临界病变（ICS-PLAD）患者发生主要不良心脏事件（MACE）的相关危险因素,建立危险因素模型预测ICS-PLAD患者发生MACE的价值,为治疗策略的选择提供指导。方法 分析行冠状动脉造影提示ICS-PLAD （最重处直径狭窄 ≥ 50%且<70%）的患者221例。采用二分类Logistic回归分析影响ICS-PLAD患者发生MACE的危险因素,建立危险因素模型。运用ROC曲线评价危险因素模型对ICS-PLAD患者发生MACE的预测价值。结果 （1）与未发生MACE组比较,发生MACE组中糖尿病、高血压和冠脉病变数 ≥ 2更常见,体重指数（BMI）、低密度脂蛋白胆固醇（LDL-C）和甘油三酯（TG）更高（P均<0.05）。（2）采用二分类Logistic回归分析显示,TG （OR=2.447,P=0.000,95% CI：1.608~3.725）、LDL-C （OR=1.971,P=0.006,95% CI：1.219~3.187）及冠脉病变数 ≥ 2（OR=6.596,P=0.000,95% CI：2.995~14.526）是ICS-PLAD患者发生MACE的独立危险因素,建立危险因素模型。（3）危险因素模型预测ICS-PLAD患者发生MACE的ROC曲线下面积为0.794（P=0.000）。结论 在有糖尿病、高血压、肥胖、高LDL-C血症、高TG血症或多支冠脉病变的ICS-PLAD患者中MACE发生率高,TG、LDL-C及冠脉病变数 ≥ 2是ICS-PLAD患者发生MACE的独立危险因素,由此建立的危险因素模型对ICS-PLAD患者发生MACE具有一定的预测价值。     

ICU肺部感染并鲍曼不动杆菌分离阳性患者临床特征及预后

目的 通过分析下呼吸道分泌物中分离出鲍曼不动杆菌的肺部感染患者其临床特征、对常用抗菌药物的耐药性及预后,探讨其死亡相关的危险因素。方法 回顾性分析2012年6月~2017年6月郑州大学第五附属医院ICU下呼吸道分泌物分离出鲍曼不动杆菌的肺部感染患者其临床资料,包括人口学资料、基础疾病、细菌耐药性、发病时APACHEⅡ评分、抗菌药物治疗方案;依据患者28天预后结果分为死亡组和存活组;通过单因素分析和多因素Logistic回归分析死亡相关的危险因素。结果 本研究共纳入98例患者,共分离出110株鲍曼不动杆菌,对头孢哌酮舒巴坦耐药率较低（17株）;对美罗培南（88株）、亚胺培南（80株）的耐药率较高。28天病死率54.1%;死亡危险因素分析结果显示：合并冠心病（OR=38.3,95% CI：1.81~720.10,P=0.019）、高APACHEⅡ评分（OR=3.47,95% CI：1.30~12.81,P=0.043）、高降钙素原水平（OR=2.78,95% CI：1.30~7.02,P=0.023）、APTT延长（OR=1.32,95% CI：1.03~1.71,P=0.037）为患者28天死亡的独立危险因素;APACHEⅡ评分与死亡组患者鲍曼不动杆菌培养阳性后的生存时间呈负相关（r=-0.601,P=0.000）;是否应用对鲍曼不动杆菌敏感的抗菌药物未明确影响预后。结论 肺部感染并鲍曼不动杆菌分离阳性患者合并冠心病、高APACHEⅡ评分、高降钙素原水平、APTT延长为患者28天死亡的独立危险因素;尤其是合并冠心病及基础疾病的严重程度决定患者的预后。     

非透析慢性肾衰竭患者发生心功能不全危险因素分析

目的 探讨非透析慢性肾衰竭（CRF）患者发生心功能不全（HF）的危险因素,为防治心功能不全的发生提供诊疗思路。方法 回顾性分析武汉大学人民医院2015年1月~2017年1月住院且临床资料完整的慢性肾衰竭（CKD4~5期）患者289例,依据是否发生心功能不全分为两组：肾衰竭合并心力衰竭组（CRS组）和单纯肾衰竭组（对照组）。收集患者一般资料及相关辅助检查资料及实验室检验指标,采用多因素Logistic回归分析慢性肾衰竭患者发生心功能不全的相关高危因素。结果 单因素分析显示,糖尿病、血压、贫血程度、心肌损伤、白蛋白、肾功能、心肌肥厚、心包积液程度在两组间差异有统计学意义（P<0.05）。多因素Logistic回归分析结果显示,糖尿病（OR=2.308,P=0.002）、高血压（OR=2.464,P=0.000）、肌酶升高（OR=3.065,P=0.000）、低白蛋白（OR=0.845,P=0.000）、低血钙（OR=0.062,P=0.000）、高血磷（OR=2.868,P=0.004）是发生心功能不全的危险因素。结论 糖尿病、高血压、心肌损伤、低白蛋白、钙磷失衡是慢性肾衰竭患者发生心功能不全的危险因素。重视这些因素的把控对防治心功能不全具有重要意义。     

多烯磷脂酰胆碱联合还原型谷胱甘肽治疗非酒精性脂肪性肝炎疗效和安全性的Meta分析

目的 系统评价多烯磷脂酰胆碱联合还原型谷胱甘肽治疗非酒精性脂肪性肝炎（NASH）的治疗效果及安全性。方法 计算机检索PubMed、EMbase、Cochrane Library、中国知网、万方、维普及中国生物医学文献数据库（CBM）从建库到2017年10月前发表的有关多烯磷脂酰胆碱联合还原型谷胱甘肽治疗非酒精性脂肪性肝炎的随机对照试验。两名研究者独立,严格按照纳入和排除标准进行文献筛选。评价纳入文献的方法学质量,提取符合纳入标准的数据,采用RevMan 5.1软件进行Meta分析。结果 共有7项试验纳入研究,共计649例NASH患者。Meta分析结果显示：与单用多烯磷脂酰胆碱或还原型谷胱甘肽相比,多烯磷脂酰胆碱联合还原型谷胱甘肽可明显改善肝功能指标：AST（MD=-17.04, 95% CI：-26.24~-7.83, P=0.000）、ALT（MD=-15.47, 95% CI：-23.34~-7.59, P=0.000）、TG（MD=-0.76, 95% CI：-1.03~-0.49, P=0.000）、TC（MD=-0.68, 95% CI：-1.04~-0.33, P=0.000）、TBiL（MD=-6.58, 95% CI：-12.95~-0.21, P=0.040）;降低患者BMI（MD=-1.67, 95% CI：-2.40~-0.95, P=0.000）和肝脏B超评分（MD=-0.35, 95% CI：-0.47~-0.23, P=0.000）;提高临床总有效率（RR=1.27, 95% CI：1.17~1.37, P=0.000）,但并不能降低LDL水平（MD=-0.06, 95% CI：-0.32~0.19, P=0.620）,且不良反应少,安全性好。结论 多烯磷脂酰胆碱联合还原型谷胱甘肽能够明显改善NASH患者的肝脏生化指标,如AST、ALT、TG、TC、TBiL以及降低BMI和肝脏B超评分,提高临床总有效率。个别报道存在不良反应,但发生率相对较低。故多烯磷脂酰胆碱联合还原型谷胱甘肽治疗NASH疗效好,安全性高。     

糖尿病合并高血压患者血糖、血压水平与动脉硬化的相关性研究

目的 探讨糖尿病合并高血压患者血糖血压水平与动脉硬化的关系。方法 以北京某农村社区40岁及以上糖尿病合并高血压患者为研究对象,对患者进行问卷调查、体格检查、肱踝脉搏波传导速度（baPWV）检测和血样检测。根据患者糖化血红蛋白（HbA1c）、收缩压（SBP）及舒张压（DBP）水平进行分组,采用Logistic回归模型分析血糖血压水平与动脉硬化的关系。结果 共纳入1214例患者,其中动脉硬化异常（baPWV≥1700cm/s）有637人,占52.47%。相关性分析显示baPWV与HbA1c （r_s=0.174,P=0.000）、SBP （r_s=0.481,P=0.000）及DBP （r_s=0.167,P=0.000）均呈正相关。Logistic回归分析显示,调整其他危险因素后,HbA1c和SBP每增加1个四分位数间距动脉硬化异常风险分别为1.41倍（95% CI：1.16~1.70）和3.71倍（95% CI：2.80~4.91）。结论 糖尿病合并高血压患者baPWV与HbA1c及SBP显著相关,同时控制血糖和血压可能有利于降低动脉硬化异常发生风险。     

胸苷酸合成酶基因多态性与儿童急性淋巴细胞白血病风险的Meta分析

目的 综合评价胸苷酸合成酶（TS）基因del6多态性与儿童急性淋巴细胞白血病（ALL）易感性的关系。方法 系统检索Pubmed、Science Direct、Google Scholar、中国知网（CNKI）和万方数据库,获取有关TS基因del6多态性与儿童ALL发生风险的文献资料,评估纳入研究的方法学质量并提取相关数据。以比值比（OR）和95%可信区间（CI）作为效应指标评估关联强度,纳入研究之间的异质性检验和合并OR值计算采用Revman 5.3软件,发表性偏倚应用漏斗图评估。结果 共纳入6个病例-对照研究,包括ALL患儿2104例,对照2320例。Meta分析结果显示,在整体人群比较中4种遗传模型均未发现TS基因del6多态性与儿童ALL易感性有显著性关联（杂合子模型：OR=0.99,95% CI：0.85~1.15,P=0.87;纯合子模型：OR=1.11,95% CI：0.90~1.38,P=0.33;隐性模型：OR=0.97,95% CI：0.76~1.25,P=0.84;显性模型：OR=1.01,95% CI：0.88~1.17,P=0.86）;根据种族进行分层分析也未发现显著性关联。漏斗图未检测到显著性发表性偏倚,敏感度分析表明合并结果是稳健可靠的。结论 目前的Meta分析表明TS基因del6多态性与儿童ALL易感性无关联。     

社区2型糖尿病患者血尿酸水平与代谢综合征的关系

目的 探讨社区2型糖尿病患者血尿酸水平与代谢综合征的关系。方法 社区1008例2型糖尿病患者纳入本研究,根据血尿酸三分位水平将患者分为3组：T1（n=367）、T2（n=321）和T3（n=320）,比较3组患者的临床特征,分析血尿酸水平与代谢性综合征的关系。结果 3组患者在糖尿病病程、高血压、体重指数、腰臀比、肌酐、总胆固醇、高密度脂蛋白-胆固醇、空腹血糖、餐后2h血糖、空腹C肽、餐后2h C肽、糖基化血红蛋白间的差异有统计学意义（P<0.05）;3组患者代谢综合征发生率依次升高,分别为34.1%、46.1%和64.7%（P=0.000）;在校正年龄、性别、糖尿病病程、吸烟史和饮酒史等混杂因素后,以低位组作为参考,中位组和高位组患者代谢综合征的危险度分别增加1.580倍（95% CI：1.154~2.164,P=0.000）和3.611倍（95% CI：2.539~5.315,P=0.000）;2型糖尿病患者中血尿酸较高者更易合并4~5个代谢综合征组分;Binary Logistic回归分析结果显示,血尿酸三分位水平与代谢综合征的发生率显著相关（P<0.05）。结论 社区2型糖尿病患者血尿酸水平与代谢综合征密切相关,血尿酸水平增高是2型糖尿病患者代谢综合征发生的一个独立危险因素。     

两种引流方法治疗结核性胸膜炎临床疗效的Meta分析

目的 系统评价中心静脉导管胸腔闭式引流术与反复胸腔穿刺抽液术两种方法治疗结核性胸膜炎的临床疗效。方法 计算机检索Medline、Pubmed、万方、中国知网、维普等数据库等关于两种引流方法治疗结核性胸腔积液的临床疗效比较的随机对照试验,由两位研究者按照纳入和排除标准独立筛选文献、提取资料并进行质量评价,并使用RevMan 5.2软件进行Meta分析。结果 共纳入14篇符合条件文献1234例结核性胸膜炎患者。Meta分析结果显示,经中心静脉持续胸腔闭式引流术治疗的治疗组的临床疗效优于反复胸腔穿刺抽液术治疗的对照组（OR=6.09,95% CI：3.71~9.99,P=0.000）,可明显缩短胸腔积液消失时间（MD=-7.49,95% CI：-8.86~-6.12,P=0.000）,并在防止胸膜肥厚方面明显优于对照组（OR=0.28,95% CI：0.17~0.47,P=0.000）。结论 在有效抗结核治疗前提下,中心静脉导管胸腔闭式引流术治疗结核性胸膜炎的临床疗效优于反复胸腔抽液术,不仅明显缩短了胸腔积液消失时间,还能降低胸膜肥厚的发生,具有更好的临床应用价值。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.