共查询到20条相似文献,搜索用时 62 毫秒
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通过单轴向压缩实验,对正常人和牛椎间盘纤维环的粘弹性进行了定量研究。在定载荷条件下测定了材料的蠕变曲线、瞬时模量和蠕变模量,并将其与关节软骨的粘弹性进行了对比。 相似文献
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大鼠皮下组织对亲水性聚丙烯酰胺凝胶的反应 总被引:8,自引:0,他引:8
目的 评价亲水性聚丙烯酰胺凝胶(Hydrophilic polyacrylamide gel,简称HPG)的生物相容性的安全性。方法 通过HE染色、Vam-Gieson染色、SP法,比较了24只Wistar大鼠皮下组织分别对HPG、硅凝胶及注射用胶原蛋白反应的强弱程度。结果 注射用胶原蛋白引起的组织炎症反应最为剧烈,硅凝胶次之,HPG最弱。术后3~14天,硅凝胶周围波形蛋白表达量比注射下胶原蛋白高 相似文献
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以环氧氯丙烷为键合剂将胍盐低聚物(PHMG)接枝到淀粉分子上,设计了正交试验优化接枝反应条件。将产物添加到淀粉和聚乙烯醇(PVA)水溶液中,采用化学交联法合成了具有抗菌性能的淀粉-聚乙烯醇(S-PVA)水凝胶,测试了水凝胶的溶胀率、脱水率以及抗菌性能。结果表明:当反应温度为40 °C、时间为0.5 h、pH为9时,PHMG的接枝效率最高,水凝胶的溶胀率随着PVA含量的增大而减小,随着交联剂用量的增加呈现先增大后减小的趋势。S-PVA水凝胶对大肠杆菌和金黄色葡萄球菌均显示出了优异的抗菌活性,当w(PHMG)=0.2%时,抑菌率达到100%。 相似文献
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以无机粘土为交联剂制备了具有温度、pH双重敏感特性的羧甲基纤维素钠/聚(N-异丙基丙烯酰胺)/粘土半互穿网络纳米复合水凝胶(CMC/PNIPA/Clay semi-IPN),并通过红外和透射电镜对其结构和形态进行了表征。在酸性(pH=1.2)和20℃条件下,分别研究了温度和不同pH缓冲液对该凝胶溶胀度的影响,测定了复合水凝胶的力学性能。结果表明:水凝胶中的粘土被剥离成单片层,且均匀分散在凝胶网络中,起交联剂的作用,而CMC以线性大分子的形态存在;CMC/PNIPA/Clay具有良好的温度、pH双重敏感特性;凝胶的断裂伸长率>1 000%。 相似文献
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目的 研究慢性应激大鼠颈动脉窦反射(CSR)的功能变化,并观察中枢血管紧张素Ⅱ(ANGⅡ) 在其变化中的作用。方法 应激组大鼠随机足底电击2 周。在麻醉下孤离颈动脉窦,用多道仪同步记录平均动脉压(MAP)和窦内压(ISP) 。应用五参数logistic 函数拟合实验数据,并定量分析反射参数的变化。结果 慢性应激后CSR 发生慢性重调,表现为调定点移向高ISP区, 反射增益和MAP反射范围减小;侧脑室(LCV) 内注射ANGⅡ特异拮抗剂肌丙抗增压素后,与注射前相比,增益和MAP反射范围增大,调定点减小,但仍高于非应激组。LCV 注射ANGⅡ后非应激大鼠CSR增益显著性下降,调定点增大;LCV 内肌丙抗增压素预处理可完全阻断ANGⅡ的上述作用。结论 慢性应激时CSR发生了重调,反射功能受到抑制,应激对CSR 的影响机制与中枢内ANGⅡ有关 相似文献
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以含双硫键的N,N-二(3-羧基丙烯酰)胱胺(BCCy)为交联剂,在1-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐/N-羟基琥珀酰亚胺(EDC/NHS)的催化下将壳聚糖(CS)交联,在水溶液中制备了纳米微凝胶。通过红外、元素分析、纳米粒度仪和扫描电镜等对其结构和形貌进行了表征,考察了pH和还原性环境对粒径的影响。对抗癌药物喜树碱(CPT)进行了负载,考察了载药粒子在还原性环境中对药物的控释性能。结果表明:随交联剂用量的增加,纳米微凝胶的粒径减小。该纳米微凝胶具有较好的生物相容性、较显著的pH和还原敏感性。 相似文献
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APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES 总被引:13,自引:0,他引:13
Hong Zhao Tie-hu Ye* Zhi-yi Gong Yang Xue Zhang-gang Xue and Wen-qi HuangDepartment of Anesthesiology Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing Department of Anesthesiology Zhongshan Hospital Fudan University Shanghai Department of Anesthesiology the First Affiliated Hospital Zhongshan University Guangzhou 《中国医学科学杂志(英文版)》2005,20(1):59-62
FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle… 相似文献
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胡金生 《中医杂志(英文版)》2008,28(1):75-78
CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month. 相似文献
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Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor. 相似文献
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Lü Ming 《中医杂志(英文版)》2008,28(1):10-12
OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen. 相似文献
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Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P<0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet. 相似文献
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Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle. 相似文献
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In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects. 相似文献
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Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea. 相似文献
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