脉络宁伍用甘露醇治疗急性颅内高压征患儿100例临床分析

本文报道脉络宁伍用甘露醇治疗儿童急性颅内高压征。脉络宁新生儿３～５ｍｌ／次，７岁以下小儿５～１０ｍｌ／次，７岁以上小儿１０～２０ｍｌ／次，溶于５％葡萄糖１００～１５０ｍｌ中静滴，７～１０天为一疗程。２０％甘露醇每次３～５ｍｌ／ｋｇ静注，６～８小时一次，５～７天为一疗程。治疗结果：治疗组５０例，显效时间为３０５２±０８２３（天），对照组５０例，显效时间为４９８２±１６２６（天），Ｐ＜００５，治疗组有效时间为７４２３±０６２６，对照组有效时间为１０２６±０９６６，Ｐ＜００１。     

甲氰咪胍、利巴韦林、六神丸治疗带状疱疹的临床疗效

带状疱疹６１例随机分为２组，治疗组３５例（男性１９例，女性１６例，年龄１９～５５岁，平均３５岁），用甲氰咪胍０６～１０ｇ／ｄ，分３～４次口服，利巴韦林１０～１５ｍｇ／ｋｇ·ｄ，分２次肌注，六神丸研成末用温开水调成糊状涂搽，２～３次／ｄ。对照组２６例（男１５例，女１１例，年龄２０～５３岁，平均３７岁），用病毒灵０２ｇ，每日３次口服，维生素Ｂ１注射液１００ｍｇ，维生素Ｂ１２注射液２５０μｇ日１次肌注，１％龙胆紫日１次涂搽。结果，治疗组疗效优于对照组，差别有显著意义。     

贝复济治疗糖尿病足临床初步观察

采用贝复济治疗糖尿病足１４例,常规治疗组２０例为对照,临床初步观察结果如下。１材料与方法１．１一般资料随机选择我院糖尿病足住院患者３４例,其中治疗组１４例,对照组２０例;治疗组男性９例,女性５例,年龄４９～７５岁,糖尿病病程３～２０年,糖尿病足病程５～３０天,治疗前空腹血糖１２．９８±４．６３ｍｍｏｌ／Ｌ,餐后２小时血糖１６．２５±４．０５ｍｍｏｌ／Ｌ;对照组男性１３例,女性７例,年龄４５～７８岁,糖尿病病程２～２４年,糖尿病足病程７～３３天,治疗前空腹血糖 １１．４７±４．５８ｍｍｏｌ／Ｌ,餐…     

残胃炎治疗探讨—附21例报告

残胃炎治疗探讨──附２１例报告陈伟达残胃炎是胃次全切除术后，最常见的一种疾病。据报道胃部分切除后６０～１００％患者发生残胃炎［１］。本文将２０例残胃炎患者的治疗情况报告如下。１　临床资料１．１一般资料全组２１例，男性１７例，女性３例，年龄在２０～７９...     

尼群地平联用卡托普利治疗中老年人原发性高血压50例疗效观察

原发性高血压在我国中老年人中为最常见的疾病,也是引起中老年人致残致死的主要疾病之一。我校中老年教职工原发性高血压患者数较多,我院１９９６年以来应用尼群地平、卡托普利治疗原发性高血压,及两药联合应用治疗中老年教职工原发性高血压１５０例,经临床观察,疗效满意,不良反应少,现报告如下。１　临床资料１．１　一般资料　本组４５～７８岁的患者共１５０例,血压２３／１３．６ｋＰａ以上,１周前未曾服用降压药物,随机分为３组,各组５０例。Ａ组男３２例,女１８例,平均年龄６７岁。Ｂ组男４０例,女１０例,平均年龄６９岁。Ｃ组男３９例,女１１例,平均年龄６７岁。１．２　治疗方法　Ａ组口服尼群地平,１０～２０ｍｇ／次,３次／ｄ;Ｂ组口服卡托普利,１２．５～２５ｍｇ／次,３次／ｄ;Ｃ组口服尼群地平１０ｍｇ加卡托普利１２．５～２５ｍｇ,３次／ｄ。３组均连续口服１周,根据血压情况,增减剂量。连续口服１５ｄ,统计疗效。１．３　疗效标准　患者在安静状态下,每天８时及１７时各测右上肢血压１次,疗效评定按卫生部规定的降压疗效评定标准。显效：舒张压下降超过１．３３ｋＰａ,且降至正常范围或舒张压下降超过２．６７ｋＰａ;有效：舒张压下降少于１．３３ｋＰａ...     

谷氨酰胺联合雷尼替丁治疗消化性溃疡的疗效

目的：评价谷氨酰胺联合雷尼替丁对消化溃疡的疗效。方法：采用随机双盲对照设计，５９例随机民验证组１７例，口服谷氨酰胺５００ｍｇ，４次／ｄ，雷尼替丁１５０ｍｇ，２次／ｄ，对照组２２例，口服安慰剂（淀粉胶囊）２粒，４次／ｄ，雷尼替丁１５０ｍｇ２次／ｄ；开放组（２０例）给药同验证组，疗程均为４周。结果 验验证组（胃溃疡１２例，十二指肠球部溃疡５例），治愈率３５．３％，显效率５８．８％，部纺％。对照组（胃溃     

兰花茶和血紫胶囊为主治疗慢性肾炎42例

慢性肾小球肾炎是一种常见病,目前中、西医均无特效治疗药物。１９９７年２月～１９９９年２月,笔者用自制的兰花茶和血紫胶囊配合西药治疗慢性肾炎４２例（治疗组）,并与单纯的西药治疗３７例（对照组）作比较观察,现总结如下。１　临床资料１．１一般资料 两组７９例病人均为本院住院或门诊病人。治疗组４２例中,男性２２例。女性２０例;年龄１６～６４．５岁,平均（２５．５±４．８）岁;病程１～１１年,平均（４．２ ± ２．６）年;对照组３７例中,男性２１例,女性１６例;年龄１４．５～６２岁,平均（２３．５±３．６）…     

清开灵注射液与五氟利多合用治疗反应性精神病90例疗效观察

目的：评价清开灵注射液与五氟利多合用治疗反应性精神病的疗效。方法：对９０例反应性精神病患者，应用甭开灵注射液４０ｍｌ＋５％葡萄糖２００ｍｌ静滴，每日一次，疗程３０ｄ，同时口服五氟利多８０ｍｇ，每周一次，疗程９０ｄ。结果：显效６９例，有效１６例，无效５例。显效率为７７％（６９／９０），有效率为１８％（１６／９０），总有效率为９５％（８５／９０），无效率为５％（５／９０）。结论：两者合用，效果更好，有     

双黄连治疗疱疹性口炎50例疗效观察

我院自１９９８年５月至７月,采用双黄连治疗疱疹性口炎５０例,现报告如下：１　临床资料１．１　一般资料：本组５０例中男２９例,女２１例,年龄在８个月至６岁,平均年龄在２．５岁。最长病程３ｄ,最短病程１ｄ。均有高热不退伴咽痛而入院。乳儿表现为拒食、流涎。其中２７例伴咳嗽,１３例伴手足疱疹,各项实验室检查正常,血常规：８０％患者白细胞总数正常,２０％患者白细胞总数在１．０×１０９／Ｌ～１．５×１０９／Ｌ之间;对照组４８例,女２６例,男２２例,年龄６个月～５岁,平均年龄３岁,病程１ｄ～３ｄ。１．２　诊断…     

紫草油治疗新生儿尿布皮炎40例疗效观察

尿布皮炎是新生儿期最常见的皮肤病之一 ,如果处理不当常可因局部病菌入侵而导致全身性感染。我院儿科１９９６年７月至２００１年７月使用紫草油外涂治疗新生儿尿布皮炎４０例 ,报道如下。１．１一般资料在我院儿科住院的７６例新生儿尿布皮炎患儿 ,按抽签法随机分为两组。治疗组４０例 ,男性２２例 ,女性１８例 ;日龄５～２２ｄ ,平均 (９．０±２．５)ｄ ;体重１．４～５．６ｋｇ,平均 (３．２±０．６）ｋｇ;病灶分度 (按皮损范围及程度 )［１］:轻度１０例 ,中度２２例 ,重度８例。对照组３６例 ,男性２０例 ,女性１６例 ;日龄６～２０…     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.