自我放松训练对心肌收缩能力的影响

用XG-2型血液循环功能测试仪,对20人放松训练前后测试左心有效泵力的变化,表明自我放松训练可增加心肌收缩能力。     

放松训练影响动脉压的机制

放松训练是心理治疗的一种方法。利用XG—Ⅱ型血液循环功能测试仪,对16例放松训练者放松前后进行测试,分析结果证明放松训练可降低平均动脉压和外周阻力,而心脏每分输出量和血液粘度基本不变。提示降低动脉压的机制是通过小动脉扩张,血管口径增大所致。     

放松训练对乳腺癌化疗患者生命质量影响的研究

目的评价放松训练对乳腺癌化疗患者生命质量的影响。方法将87例受试者随机分为干预组和对照组,干预组常规护理+放松训练,对照组常规护理。分别在放松训练前后应用乳腺癌患者生命质量量表(QLQ-BR23)评价干预效果。结果放松训练后干预组生命质量功能领域得分明显较对照组高,症状领域中疲乏、气短、失眠等有所缓解,差异有显著性(P<0.05或P<0.01)。结论放松训练能够抵消化疗导致的心理应激,缓解疲乏、脱发烦恼和疼痛等症状,改善睡眠质量,提高患者生命质量。     

对康复期抑郁症患者实施放松训练后的临床效果观察

目的：探讨放松训练对精神科康复期抑郁症患者焦虑心理及预后的影响。方法：将在本科住院的60例抑郁症患者在药物治疗和常规护理4周后,对其实施放松训练,使患者情绪镇静、心理放松,减轻其焦虑抑郁心理,2周后进行焦虑抑郁评分。结果：放松训练后患者的焦虑抑郁状态明显低于放松训练前的焦虑抑郁状态（包括药物疗效）（P〈0.05）,放松训练后家属满意度明显提高（P〈0.05）。结论：放松训练可减轻康复期抑郁症患者的焦虑抑郁心理,促进和谐的医患关系,提高患者治疗依从性及生活质量。     

综合放松训练对结肠癌围手术期患者心理应激水平的研究

目的:探讨结肠癌患者围手术期在实施综合放松训练前后的心理应激状态,明确综合放松训练对减轻应激反应,稳定患者情绪,促进疾病康复等方面的作用。方法:将经确诊需接受结肠癌根治术治疗符合研究纳入标准的患者80例,随机分为实验组和对照组各40例。从分析心理应激水平和免疫功能入手,对两组患者在围手术期实施综合放松训练疗法,对实施前后的心理应激状态、免疫功能进行数据分析,明确综合放松训练对减轻患者应激反应,稳定情绪,促进疾病康复等方面的作用。结果:两组患者术前第2天SAS、SDS评分差异无显著性(P>0.05),无统计学意义。术后第15天实验组患者SAS、SDS测量结果均低于对照组,差异有显著性(P<0.05),具有统计学意义。结论:综合放松训练能明显改善结肠癌患者围手术期心理应激水平。     

基本体操训练对5—6岁幼儿心脏功能的影响

观察４０名５－６岁幼儿进行６个月的基本体操训练后心脏功能的指标。结果：安静状态下心率明显下降，收缩压有所增高，３０ｍ全速直线跑后恢复时间明显缩短。认为适度的中小强度基本体操训练对幼儿心脏发育及增强心脏功能十分有益。     

骨骼肌松弛时心血管活动的变化

用ＸＧ一Ｚ型血液循环功能测试仪对３０人放松训练前、中测试结果表明，在骨骼肌放松时，心率、平均动脉压和外周阻力下降；每搏输出量与左心有效泵力上升；微循环无明显变化     

LPL基因C1573T多态性与耐力训练对心脏影响的研究

目的探讨脂蛋白脂酶C1573T单核苷酸多态性与有氧耐力训练对心脏结构和功能的影响。方法选择102名从未参加专业训练来自中国北方地区男性士兵作为受试者。对所有受试者运用PCR-RFLP法测定LPL基因内含子6C1573T基因多态性。并对所有受试者进行为期18周的耐力训练,采取递增负荷运动实验测定受试对象训练前后左心室结构和功能。结果3种基因型的分布频率分别为CC:40(0.39),CT:43(0.42),TT:19(0.19)。以单因素方差分析对比不同基因型群心脏结构和功能。训练前3个基因型群间心脏结构和功能的多个指标差异存在显著性(P<0.05)。CT基因型群心脏结构和功能训练敏感性明显大于其他两个基因型群(P<0.05)。结论3个基因型群间心脏结构和功能存在初始遗传水平的差异并显示CT基因型群心脏的结构和功能对运动训练更敏感。     

飞行人员生物反馈放松训练效果评价

目的评价航空心理训练中对飞行人员实施生物反馈放松训练的效果。方法分别采用渐进性肌肉放松、呼吸调整放松、意向放松和音乐放松等四种方法进行反馈训练,对训练中心率、压力指数和PNN50生理指标进行统计分析。结果训练前、中和后期各生理指标变化的差异有统计学意义（P〈0.05或P〈0.01）;四种训练方法之间生理指标变化无差异（P〉0.05）;低年龄组心率变化在训练前和训练中、训练后与中间和高年龄组比较差异有统计学意义（P〈0.01）。结论飞行人员生物反馈放松训练效果明显,不同放松方法的训练效果比较差异无统计学意义;不同年龄组训练效果差异有统计学意义,低年龄组训练效果好于中间和高年龄组。     

心理支持护理联合意向放松训练在中晚期肺癌患者中的应用

〔目的〕探讨中晚期肺癌患者采用心理支持护理联合意向放松训练的效果.〔方法〕选取2019年1月至2020年12月期间某医院胸外科收治的60例中晚期肺癌患者作为研究对象,采用随机数字表法分为对照组(30例)和观察组(30例).对照组采用常规护理联合意向放松训练干预,观察组采用心理支持护理联合意向放松训练干预,两组均干预至患者出院.比较干预前及出院时两组的心理状态(焦虑自评量表、抑郁自评量表)及自我感受负担(自我感受负担量表).〔结果〕出院时,两组焦虑自评量表、抑郁自评量表评分、身体、情感、经济负担及总分均低于干预前,且观察组低于对照组,差异有统计学意义(P<0.05).〔结论〕心理支持护理联合意向放松训练可缓解患者焦虑、抑郁负性情绪,减轻自我感受负担.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.