内侧髌股韧带重建联合胫骨结节移位术治疗复发性髌骨脱位疗效分析

目的:探讨内侧髌股韧带(MPFL)重建联合胫骨结节移位术治疗复发性髌骨脱位的临床疗效。方法:自2011年3月至2013年12月,共收治复发性髌骨脱位19例(22膝),男6例,女13例(16膝),年龄17-31岁,平均21.4岁,手术均采用MPFL重建联合胫骨结节移位,手术前后应用Lysholm评分、Kujala评分及影像学评价膝关节功能。结果:术后随访6-18月(平均8.5月),19例患者术后髌骨恐惧试验均为阴性,随访期间无骨折及髌骨再脱位发生,髌骨轴位X线片和CT示髌股解剖关系恢复正常。术后末次Lysholm评分及Kujala评分分别为93.91±5.14和92.45±7.32,末次随访时髌股适合角、髌骨外移率及髌骨倾斜角分别为(5.68±2.14)°、(4.21±1.34)°和(5.57±2.51)°,与术前比差异均有统计学意义。结论:MPFL重建联合胫骨结节移位术能缓解症状,恢复膝关节功能,是治疗复发性髌骨脱位的有效方法。     

改良单骨道双束重建内侧髌股韧带治疗复发性髌骨脱位的临床研究

目的:探讨改良单骨道双束重建内侧髌股韧带治疗复发性髌骨脱的临床应用价值。方法:对33例复发性髌骨脱位患者行改良单骨道技术双束重建内侧髌股韧带联合关节镜下髌骨外侧支持带松解加胫骨结节内移治疗。术后观察切口愈合情况,髌骨稳定性,膝关节X片检查测量对比术前、术后髌骨适配角、髌骨倾斜角、外侧髌股角,采用Lysholm和Kujala评分评估膝关节功能。结果:33例均获随访,时间8~15个月,平均(12±3.1)月。切口按期愈合,无感染,髌骨稳定,运动能力恢复,33例病例均无髌骨再脱位,两组患者的术前、术后髌骨适配角为(21.8±5.9)°、(-2.5±4.0)°,髌骨倾斜角(24.9±5.8)°、(14.8±4.2)°,外侧髌股角(-6.1±2.3)°、(5.4±1.6)°。Lysholm评分术前、术后分别为(35.10±9.31)分和(89.11±5.21)分,Kujala评分术前、术后分别为(36.26±13.36)分和(90.45±4.55)分,比较差异有统计学意义(P0.05)。结论:改良单骨道双束重建技术重建内侧髌股韧带具有操作简单,牢固可靠、并发症少、住院费用低的优点,联合关节镜下髌骨外侧支持带松解加胫骨结节内移,可取的良好的治疗效果。     

关节镜辅助下内侧髌股韧带重建治疗习惯性髌骨脱位

目的探讨习惯性髌骨脱位的手术治疗,评价自体半腱肌腱重建内侧髌股韧带的疗效。方法回顾性分析我科收治的18例(20膝)习惯性髌骨脱位患者,在关节镜辅助下采用自体半腱肌腱重建内侧髌股韧带,部分患者行关节镜下外侧支持带松解。结果 18例(20膝)患者术后全部获得随访,平均为(12.6±4.3)个月。术后均未发现髌骨再次脱位、无髌骨错动或半脱位,髌骨倾斜试验、髌骨外推试验阴性,关节功能评分:Kujala评分由(62.40±6.08)提高为(88.09±5.43);Lysholm评分由(64.16±4.66)提高为(91.28±4.15),P<0.05。结论自体半腱肌腱重建内侧髌股韧带治疗习惯性髌骨脱位,能纠正不良的髌骨轨迹,改善患者主观症状,提高膝关节功能。短期临床观察无复发性脱位发生,是治疗习惯性髌骨脱位的一种有效手术方法。但远期疗效需要长期的随访。     

新三联手术治疗习惯性髌骨脱位的近期疗效观察

目的探讨髌骨外侧广泛松解胫骨结节移位髌股内侧韧带重建三联手术治疗习惯性髌骨脱位的可行性及近期的疗效。方法对自我院2015年7月～2017年3月收治的18例经临床检查确诊为习惯性髌骨脱位的患者临床资料进行回顾性分析,其中男8例,女10例,年龄18～37岁,平均的年龄23.85岁,采用髌骨外侧广泛松解胫骨结节移位髌股内侧韧带重建为主的新三联手术。手术前后对患者的膝关节的功能行Lysholm、Kujala评分。使用SPSS 20.0统计学软件进行配对设计资料t检验,P0.05为差别有显著性。结果所有病人获得随访,时间12～26个月(平均18个月),无髌骨再脱位的发生,恐惧测验均为阴性。末次随访膝关节髌股关节疼痛2膝,膝关节肌力减退4膝,关节僵硬2膝, Lysholm评分术前平均(55.15±5.008),术后末次随访平均(85.15±3.468),Kujala评分术前平均(50.55±7.444),术后末次随访平均81.55±3.069)。术前CT示TT-TG值为(29.875±2.6115)mm,术后CT示TT-TG值为(12.135±2.3504)mm,统计学软件分析P值0.05,差别有统计学的意义。结论髌骨外侧广泛松解胫骨结节移位髌股内侧韧带重建三联手术为主的综合手术方法医治习惯性髌骨脱位近期临床效果肯定,可有效治疗习惯性髌骨脱位,防止髌骨脱位的复发。     

关节镜辅助下内侧髌股韧带双束重建治疗复发性髌骨脱位

目的:探讨关节镜辅助下解剖重建内侧髌股韧带治疗复发性髌骨脱位的手术方法及疗效。方法:选取2010年3月~2015年8月因复发性髌骨脱位接受手术治疗的患者20例,其中男6例,女14例;年龄19~34岁,平均(23.6±4.54)岁;右膝15例,左膝5例。19例有明确膝关节外伤史。采用自体半腱肌肌腱移植配合关节镜下内侧髌股韧带双束解剖重建、外侧支持带松解的方法治疗,并应用Lysholm和Kujala评分评价膝关节功能。结果:所有患者术后均获得随访,平均随访时间(22±5.42)个月(12~30个月)。Lysholm评分术前为(60.05±3.53)分,术后为(92.80±1.74)分,两者比较差异有统计学意义(t=-42.680,P<0.01)。Kujala主观评分术前为(59.95±3.52)分,术后为(93.35±2.66)分,两者比较差异有统计学意义(t=-53.375,P<0.01)。所有患者均未再出现脱位情况,髌骨外推及恐惧试验均为阴性。结论:关节镜辅助下行双束解剖重建内侧髌骨韧带是治疗复发性髌骨脱位的有效方法之一,且具有微创、安全、针对性强、术后功能恢复快等优点。     

内侧髌股韧带重建治疗髌骨复发性脱位的护理体会

目的探讨内侧髌股韧带重建治疗髌骨复发脱位患者的围手术期护理。方法对52例髌骨脱位患者,手术前后采用Kujala及Lysholm膝关节功能综合评分,比较髌股关节不稳症状恢复情况,并行髌骨轴位片检查进行术前术后对比。结果 Kujala术前评分(41.2±8.3),与术后评分(85.0±4.5)比较,差异有统计学意义(P<0.01);LyshohI术前评分(41.5±6.8)分与术后评分(86.3±3.8)比较,差异有统计学意义(P<0.01),髌股关节功能有明显改善。结论对内侧髌股韧带重建髌骨复发性脱位患者手术前后正确的护理,是确保手术成功及功能康复的重要手段。     

韧带重建结合关节镜下松解治疗复发性髌骨脱位

目的观察小切口内侧髌股韧带重建结合关节镜下外侧支持带的松解治疗复发性髌骨脱位。方法 2005年5月至2010年5月在我院骨科将34例（38膝）髌骨复发性髌骨脱位的患者采用小切口内侧髌股韧带重建结合关节镜下外侧支持带的松解进行治疗,术后30例（32膝）获得随访,随访时间18～36个月,平均随访时间26.3个月,对随访的患者根据Kujala髌股关节不稳定症状评分表和Lysholm膝关节日常活动评分表评估手术前和手术后12月的疗效,并同时观察手术前和手术后12月膝关节屈曲30°位时CT扫描髌股关节的适合角（CA）、外侧髌股角（LPA）的变化,通过Spass18.0进行配对t检验统计学处理,数据以（x±s）表示,检验水准P〈0.05。结果 30例（32膝）均获随访,随访时间18～36个月,平均随访时间21.3个月;手术前和手术后12月膝关节功能评分进行比较,P〈0.05,有统计学意义,手术后12月进行恐惧试验、髌骨倾斜试验、髌股关节研磨试验检查均为阴性;手术前和手术后12月屈膝30°CT测量值比较,P〈0.05,有统计学意义。结论小切口内侧髌股韧带重建结合关节镜下外侧支持带的松解治疗髌骨复发性脱位疗效确切,并发症少,是治疗复发性髌骨脱位的有效方法。     

关节镜下内侧髌股韧带重建治疗复发性髌骨脱位

目的对关节镜下内侧髌骨韧带(MPFL)重建治疗复发性髌骨脱位的临床效果进行评估;方法 2013年4月自2015年10月住院治疗的复发性髌骨脱位患者15位(18膝),男性6位(8膝),女性9位(10膝),年龄14-29岁,平均年龄20岁。用自体半腱肌肌腱在关节镜下行内侧髌股韧带重建,髌骨侧缝合铆钉,股骨侧挤压螺钉;术后14例获得随访,随访时间7-24月,平均14个月,随访内容有恐惧试验、髌骨倾斜角.Lyshomn和Kujala评分。结果恐惧试验均阴性,膝关节稳定性提高,随访期间无发生再脱位,1例在术后10周出现膝关节活动受限,经康复治疗后恢复正常;髌骨倾斜角较术前减小(P0.05),术后Lysholm和Kujala评分较术前提高(P0.05)。结论关节镜下MPFL重建治疗复发性髌骨脱位可有效防止髌骨再脱位,改善患者膝关节功能,明显提高膝关节稳定性。     

关节镜辅助下内侧髌股韧带重建治疗复发性髌骨脱位

目的探讨关节镜辅助下内侧髌股韧带(MPFL)重建治疗复发性髌骨脱位的方法和临床疗效。方法将2008年7月至2010年9月该院收治的复发性髌骨脱位13例患者,全部采用关节镜辅助下自体半腱肌腱移植重建MPFL,术前、术后1年按照Lysholm评分评价膝关节功能。结果所有患者均获随访,随访时间1.1～3.2年,平均1.7年,均无髌骨再脱位发生及关节活动度受限。Lysholm评分术前平均为(73.5±4.7)分,术后1年平均为(94.7±4.5)分,移植前、后Lysholm评分比较差异有统计学意义(P<0.01)。结论采用关节镜辅助下MPFL重建,操作简单、微创、髌骨稳定性好,是治疗复发性髌骨脱位的有效方法。     

关节镜下三联术治疗复发性髌骨脱位

目的:探讨关节镜辅助下三联术治疗复发性髌骨脱位的疗效。方法:应用关节镜辅助下髌股外侧支持带松解、内侧支持带重建、胫骨结节截骨内移抬高术治疗复发性髌骨脱位16例。体格检查恐惧试验阳性,被动活动受限。结果:术后切口均Ⅰ期愈合。16例均获随访,随访时间12²4个月,平均16.7个月。随访期间均无髌骨脱位再发生。术后1年膝关节Lysholm评分为(95.7±4.2)分,明显高于术前的(63.7±5.3)分,差异有统计学意义(P<0.05);术后1年Kujala评分为(90.3±2.6)分,也明显高于术前的(61.3±4.3)分,差异有统计学意义(P<0.05)。结论:关节镜辅助下三联术治疗复发性髌骨脱位的关节创伤小,恢复佳,值得在临床工作中广泛应用。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.