口服法低剂量多层螺旋CT小肠造影的应用价值

目的探讨口服等渗甘露醇法低剂量多层螺旋CT小肠造影(Multislice computed tomography enterography,MSCTE)对小肠疾病的诊断价值。方法对62例临床怀疑小肠疾病患者口服2.5%等渗甘露醇溶液及肌注山莨菪碱后随机分组分别行常规剂量和低剂量MSCTE检查,将诊断结果与手术病理、内镜病理或临床随访结果进行对照,评估常规剂量和低剂量MSCTE对小肠疾病的诊断价值并比较二者诊断准确率有无差异。结果经病理及随访结果证实小肠疾病57例,常规剂量MSCTE诊断敏感性89.28%、特异性80.00%、准确率87.87%,低剂量MSCTE诊断敏感性88.46%、特异性100.00%、准确率89.65%。两种检查方法诊断准确率有无统计学差异(χ~2=3.27,P=0.574)。结论口服等渗甘露醇法低剂量MSCTE在多种小肠疾病有较高的诊断价值。     

多层螺旋CT肠道造影在小肠病变中的临床应用

目的:探讨多层螺旋CT肠道造影(multislice spiral CT enterography,MSCTE)在小肠病变检查中的临床应用价值。方法:选取本院2015年1月-2016年10月收治的76例疑似小肠疾病患者,所有患者于45 min内分3~4次口服20%的甘露醇溶液+碘佛醇注射液+温开水共2 000 m L;约75 min行全腹部CT平扫和增强扫描,将MSCTE检查结果与CT平扫、手术病理或内窥镜检查进行对比分析,评估MSCTE在小肠肿瘤性病变、小肠炎症性病变等小肠病变中的诊断符合率、敏感性、特异性、阳性预测值和阴性预测值。结果:所有患者均顺利完成CT平扫和MSCTE检查,MSCTE的诊断符合率为94.74%,明显高于CT平扫的47.37%,差异有统计学意义(X~2=41.455,P0.01);MSCTE的敏感性、特异性、阳性预测值和阴性预测值分别为96.43%、90.00%、90.00%和96.43%均明显高于CT平扫法的65.63%、34.09%、57.69%和42.00%,差异均有统计学意义(P0.05)。结论:与常规CT平扫相比,MSCTE检查应用于小肠病变诊断中具有更高的诊断符合率、敏感性和特异性,明显提高小肠疾病的诊断能力,在小肠病变检查中值得推荐应用。     

多层螺旋CT小肠造影在小肠梗阻诊断中的价值

目的 探讨多层螺旋CT(MSCT)小肠造影(MSCTE)在小肠梗阻的部位、程度及病因诊断中的价值.方法 回顾性分析52例经手术、组织病理学或临床治疗证实病因为小肠梗阻的患者MSCT平扫及MSCTE资料,计算MSCTE及MSCT平扫判断小肠梗阻部位、程度的准确性和MSCTE在小肠梗阻病因诊断中的准确率、假阳性率、假阴性率、敏感性.结果 52例患者中机械性小肠梗阻46例,血运性肠梗阻5例,麻痹性肠梗阻1例,其中37例有MSCT平扫资料.机械性小肠梗阻中32例有MSCT平扫资料,MSCTE与MSCT平扫判断机械性小肠梗阻部位、梗阻程度的准确性比较,差异无统计学意义(P＞0.05);MSCTE对小肠梗阻病因的诊断正确率高于MSCT平扫(P＜0.01);MSCTE对小肠梗阻病因诊断的假阳性率和假阴性率均为9.62％,敏感性为90.38％.结论 MSCTE在小肠充分扩张的基础上,联合运用多种图像后处理技术,可以明显提高对小肠梗阻病因的诊断准确性,具有较高的临床应用价值.     

MSCTE和MSCTA联合运用在小肠梗阻病因诊断中的价值

目的探讨多层CT小肠造影(MSCTE)和多层CT血管造影(MSCTA)联合运用在小肠梗阻病因诊断中的价值。方法回顾性分析57例行MSCTE和MSCTA检查,并经过手术和病理检查证实为小肠梗阻患者的影像学资料。使用Siemens Somatom Sensation 64层螺旋CT进行检查,经过后处理方法[多平面重建(MPR)、最大密度投影(MIP)、容积再现技术(VRT)、曲面重建法(CPR)],分析其图像在小肠梗阻病因诊断中的作用。结果所有病例中,肿瘤15例,粘连14例,腹外疝8例,炎症6例,内疝或扭转5例,肠套叠3例,胆石或粪石4例,血管性2例。组Ⅰ:常规横断位结合MPR、CPR对病因诊断的准确性为89.5%(51/57);组Ⅱ:常规横断位结合MPR、CPR和CTA技术(VRT、MIP)对病因诊断的准确性为94.7%(54/57);组Ⅱ的诊断准确性明显高于组Ⅰ(P<0.05)。结论 MSCTA和MSCTE的联合运用可以明显提高小肠梗阻病因诊断的准确性,具有较高的临床应用价值。     

MSCT CTA与DSA诊断肾癌的应用对照研究

目的 探讨多层螺旋CT血管成像法MSCT(CTA)与选择性肾动脉数字减影血管造影法(DSA)对诊断肾癌的应用价值. 方法 对26例病理证实的肾癌患者的多层螺旋CT血管成像MS(2T(CTA)与选择性肾动脉数字减影血管造影(DSA)的影像特征进行对照分析. 结果 多层螺旋CT血管成像法MSCT(CTA)对肾癌的肿瘤血供类型、肿瘤供血动脉来源的诊断符合率和肾动脉解剖显示正确率达到96.15%.选择性肾动脉数字减影血管造影法(DSA)对肾癌的肿瘤血供类型、肿瘤供血动脉来源的诊断合率和肾动脉解剖显示正确率达到92.31%. 结论 多层螺旋CT血管成像法MSCT(CTA)与选择性肾动脉数字减影血管造影法(DSA)对诊断肾癌都具有较高的临床诊断价值,两组正确率的比较,没有显著性差异.多层螺旋CT血管成像法MS(3T(CTA)比选择性肾动脉数字减影血管造影法(DSA)对指导肾癌的介入与外科手术治疗具有较大的使用价值.     

MSCT CTA与DSA诊断肾癌的应用对照研究

目的 探讨多层螺旋CT血管成像法MSCT(CTA)与选择性肾动脉数字减影血管造影法(DSA)对诊断肾癌的应用价值. 方法 对26例病理证实的肾癌患者的多层螺旋CT血管成像MSCT(CTA)与选择性肾动脉数字减影血管造影(DSA)的影像特征进行对照分析. 结果 多层螺旋CT血管成像法MSCT(CTA)对肾癌的肿瘤血供类型,肿瘤供血动脉来源的诊断符合率和肾动脉解剖显示正确率达到96.15%.选择性肾动脉数字减影血管造影法(DSA)对肾癌的肿瘤血供类型,肿瘤供血动脉来源的诊断合率和肾动脉解剖显示正确率达到92.31%. 结论 多层螺旋CT血管成像法MSCT(GTA)与选择性肾动脉数字减影血管造影法(DSA)对诊断肾癌都具有较高的临床诊断价值,两组正确率的比较,没有显著性差异.多层螺旋CT血管成像法MSCT(CTA)比选择性肾动脉数字减影血管造影法(DSA)对指导肾癌的介入与外科手术治疗具有较大的使用价值.     

MSCT CTA与DSA诊断肾癌的应用对照研究

目的 探讨多层螺旋CT血管成像法MSCT(CTA)与选择性肾动脉数字减影血管造影法(DSA)对诊断肾癌的应用价值. 方法 对26例病理证实的肾癌患者的多层螺旋CT血管成像MSCT(CTA)与选择性肾动脉数字减影血管造影(DSA)的影像特征进行对照分析. 结果 多层螺旋CT血管成像法MSCT(CTA)对肾癌的肿瘤血供类型,肿瘤供血动脉来源的诊断符合率和肾动脉解剖显示正确率达到96.15%.选择性肾动脉数字减影血管造影法(DSA)对肾癌的肿瘤血供类型,肿瘤供血动脉来源的诊断合率和肾动脉解剖显示正确率达到92.31%. 结论 多层螺旋CT血管成像法MSCT(GTA)与选择性肾动脉数字减影血管造影法(DSA)对诊断肾癌都具有较高的临床诊断价值,两组正确率的比较,没有显著性差异.多层螺旋CT血管成像法MSCT(CTA)比选择性肾动脉数字减影血管造影法(DSA)对指导肾癌的介入与外科手术治疗具有较大的使用价值.     

小肠出血的诊断方法及病因分析

目的探讨小肠出血的诊断方法及病因分析。方法回顾性分析郑州市第一人民医院2011年7月至2017年12月收治的37例小肠出血患者的临床资料。结果各检查方法在小肠出血的检查中阳性率分别为:术中内镜100%,结肠镜11.8%,多层螺旋CT扫描(MSCT)8.8%,数字减影血管造影(DSA)69.2%.胶囊内镜71.4%,气钡双重造影21.4%,小肠镜46.7%。37例小肠出血患者中33例检查结果阳性,其中小肠肿瘤10例(27.0%),血管病变10例(27.0%),炎症性肠病5例(13.5%),憩室7例(18.9%),小肠钩虫1例(2.7%);原因不明4例(10.8%)。结论小肠出血病因多样,检查缺乏特异性,根据出血的缓急可选择合适的检查方法,胶囊内镜、DSA、小肠镜检查的检出率较高。小肠出血肿瘤、血管畸形最为多见。     

口服CT小肠造影的临床应用

目的探寻口服CT小肠造影的可行性和临床应用价值。方法疑似小肠病变的患者在45～60min内分3～4次口服完等渗甘露醇溶液1500～2000mL;评估小肠肠管充盈满意度与扩张度,对肠管病变进行分析（肠壁病理改变、肠腔狭窄和肠系膜淋巴及血管病理性征象）;计算小肠CT造影检查检出病变的敏感性、特异性、阳性预测值及阴性预测值。结果等渗甘露醇溶液得到所有病人接受、认可;肠道充盈满意度：5例欠佳,10例较满意,45例满意;无小肠梗阻的各段小肠扩张度分别：十二指肠（23.2±3.2）mm,空肠（25.7±3.9）mm,回肠（21.7±2.2）mm;小肠梗阻的各段小肠扩张度分别：十二指肠（22.2±2.5）mm,空肠（41.4±9.7）mm,回肠（43.6±11.6）mm。多种小肠疾患的肠内、肠壁、肠系膜及腹内脏器情况MSCTE都显示清楚。口服CT小肠造影检出小肠病变的灵敏性、特异性、正确率、阳性预测值及阴性预测值分别为97.9%、91.7%、96.7%、97.9%、91.7%。结论口服小肠造影是检测小肠病变的简洁、安全可靠并能全景展示小肠管的方法,同时是小肠与腹腔内其他脏器疾病鉴别的较为可靠手段。     

小肠原发性肿瘤31例临床分析

目的 探讨原发性小肠肿瘤的临床特点及诊断.方法 回顾性分析近5年来我们所收治的31例原发性小肠肿瘤的临床和病理特征.结果 小肠肿瘤大多位于十二指肠,占21/31(67.74%).全组术前确诊率为17/31(54.84%).其中,十二指肠肿瘤较高66.67%(14/21);空回肠肿瘤术前诊断率较低,仅3例30%(3/10).本组患者以恶性病变28例,以腺癌占绝大多数24/31(77.42%),其次为恶性淋巴瘤4/31(12.90%).良性肿瘤仅3例.小肠肿瘤可表现为腹痛、腹块、消化道出血、肠梗阻和黄疸、发热等.X线钡餐,特别是低张小肠气钡造影和内镜对诊断小肠肿瘤有较大帮助.选择性肠系膜上动脉血管造影对小肠肿瘤,特别是诊断困难的小肠出血有诊断价值.CT对判断肿瘤有一定帮助.结论 小肠肿瘤以恶性者和腺癌多见,又以十二指肠为主.十二指肠水平都以上肿瘤以消化道内镜检查加活检为首选.低张小肠造影是有效的诊断和定位方法.肠系膜上动脉造影对血管瘤和平滑肌瘤是较好的方法.CT也有一定帮助.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.