包头市区294例肝癌住院病例特征分析

目的：根据收集到的294例肝癌住院病例,了解1995-2003年包头市区肝癌的发病特征,为肝癌的防制和流行病学研究提供依据。方法：收集包头市区所有能收治恶性肿瘤病人的18所区级以上医院的1995、1997、1999、2001、2003年恶性肿瘤首诊病案,填写调查表,抽取其中的肝癌病例进行统计分析。结果：获得肝癌病例294例,男性213例（占72.4%）,女性81例（占27.6%）。发病年龄范围22-88岁,平均年龄59.5岁,病例主要集中在35-75岁（占总数的89.5%）。发病率由1995年的1.04/10万上升到2003年的6.89/10万,增长速度为30.92%。首诊病人中有93.9%处于癌症中晚期,有43.0%患者已转移。结论：肝癌严重影响着包头人民的的健康水平,应加大防制力度。     

包头市区1995-2001年恶性肿瘤住院病人构成及变化趋势分析

目的:了解包头市区1995 -2001年恶性肿瘤发病情况.方法:于2002年6月到2003年9月查阅了包头市区所有区级以上18所医院的1995、1997、1999、2001年各年住院病案,以在包头首次住院的恶性肿瘤病例为研究对象,由经统一培训的调查员查阅病例填写调查表.根据ICD-10进行恶性肿瘤分类,利用SPSS软件统计分析.结果: 获得恶性肿瘤病例3 486人,其中1995年472人、1997年801人、1999年944人、2001年1 269人.以上4年总计前六位恶性肿瘤发病系统依次为消化器官、呼吸和胸腔内器官、乳房、女性生殖器官、淋巴造血和有关组织、泌尿道;男性前十位恶性肿瘤依次为肺癌、胃癌、食道癌、直肠癌、肝癌、结肠癌、膀胱癌、白血病、喉癌、胰腺癌;女性为乳腺癌、肺癌、胃癌、卵巢癌、直肠癌、宫颈癌、结肠癌、甲状腺癌、食道癌、肝癌.结论:包头市区恶性肿瘤防治,男性应以肺癌和消化道癌症(胃癌、食道癌、直肠癌、结肠癌)为重点,女性以乳腺癌、肺癌、生殖系统癌症(卵巢癌、宫颈癌)、消化道癌症(胃癌、直肠癌、结肠癌)为重点,尤其是肺癌和乳腺癌应是恶性肿瘤防治中的重中之重.     

多发性骨髓瘤34例实验室分析

<正> 多发性骨髓瘤为较常见的浆细胞的一种恶性肿瘤,因临床表现多样,起病隐袭等,易致误诊,今对我室在1990年至1995年所见34例多发性骨髓瘤病人进行实验室分析报道。 一般材料 本文报告我院自1990年至1995年5年中收治的34例多发性骨髓瘤病人。均为首诊病例,其中男性20例,女性14例,男女比例为1.93:1,发病年龄33～87     

23例肺癌误诊为肺结核临床分析

近年来,肺癌作为常见的恶性肿瘤,发病率在多数国家和地区有明显增高的趋势,但临床上早期确诊率不高,极易误诊为肺结核,现将我院1995年7月至2003年8月门诊和住院收治的肺癌患者中,首诊误诊为肺结核的23例患者情况总结分析如下。     

重庆市恶性肿瘤发病死亡现状调查研究

目的 通过对重庆市恶性肿瘤发病死亡现状进行调查分析,进一步了解重庆市恶性肿瘤流行趋势、危险因素、肿瘤类别及顺位情况,为制定肿瘤防治研究策略提供重要依据.方法 整理重庆市近9年恶性肿瘤发病死亡登记数据,采用国际编码ICD-10进行登记,统计、分析不同职业、年龄、性别恶性肿瘤发病情况.结果 1999～2007年恶性肿瘤平均新发病率为122.37/10万,肺癌排第一,占34.44/10万;前三位职业分别为工人/农民、干部及离退休人员、家务及待业人员;35～85岁为肿瘤发病高峰期,45～50岁、65～75岁为肿瘤发病高峰年龄段;2003年恶性肿瘤死亡率为114.51/10万,2006年全国第3次死因调查,重庆市恶性肿瘤死亡率为26.8%.结论 重庆市恶性肿瘤发病率逐年上升,癌症高发地区多在农村和西部地区,恶性肿瘤已成为威胁居民身体健康的主要疾病.开展癌症的早诊早治工作是提高生存率及降低发病率和死亡率的主要策略之一.     

2003年至2007年肺癌住院病人构成分析

目的 对医院肺癌住院病人进行分析,了解医院肺癌收治的动态变化,为医院重点学科建设提供决策依据.方法 以2003至2007年云南省肿瘤医院的首诊肺癌入院患者为研究对象,分析这些患者的增长趋势、性别构成、病理类型、病死构成情况和治疗结果 .结果 住院肺癌病人近年来增长速度最快,成为医院收治的第一大恶性肿瘤;肺腺癌已经超过鳞癌成为第一大病理类型;肺癌住院病人病死率经过综合治疗后在逐渐降低;能手术的早期病例在总病例中所占比例为22.98%.结论 肺癌患者逐年增多,尤其是肺腺癌增长迅速.对肺癌进行综合治疗,可能降低住院病人病死率.     

2018-2021年大理州某医院恶性肿瘤患者疾病谱分析

目的 分析大理州某医院恶性肿瘤患者疾病谱,为开展恶性肿瘤防治工作提供科学依据。方法收集2018年1月1日-2021年12月31日大理州某医院恶性肿瘤病例资料,采用ICD-10编码进行疾病分类,分析统计不同年龄、性别和癌种的分布特点。结果 4年间医院共收治恶性肿瘤患者6015例,其中男性2961例,女性3054例。病例呈逐年增长的趋势,男女患者构成比较,差异无统计学意义。患者平均年龄为56.96±12.71岁,各年龄段之间患者病例数差异有统计学意义,且发病类别不同。恶性肿瘤构成比前10位依次是：肺癌、乳腺癌、甲状腺癌、直肠癌、胃癌、肝癌、结肠癌、食管癌、膀胱癌、前列腺癌,占全部恶性肿瘤的77.77%。结论 恶性肿瘤患者发病具有年龄、癌种差异,肺癌、乳腺癌、甲状腺癌、消化道癌仍是目前的防治重点,大理州相关部门应针对重点人群开展综合防控措施,开展早诊早治工作。     

包头市2002-2003年女性乳腺癌病例特征分析

目的：了解2002-2003年包头市女性乳腺癌的患病特征。方法：以包头市2002-2003年所有就住市内区级以上医院的恶性肿瘤病人为研究对象,抽取其中女性乳腺癌病人的资料进行统计分析。结果：包头市乳腺癌占女性恶性肿瘤的26．3％,居恶性肿瘤的第一位;女性乳腺癌的患病年龄在28-79岁之间,主要集中在40-60岁,平均发病年龄为49岁;就诊时转移率为28．1％;58．6％的患者于肿瘤中期就诊。结论：应加强对乳腺癌防治的健康教育。对35岁以上妇女,特别是具有乳腺癌易患因素的高危人群,应定期进行乳腺专科检查,以便乳腺癌早期发现及时治疗。     

肇庆市16 217例恶性肿瘤住院患者疾病谱分析

目的开展对肇庆市恶性肿瘤住院患者的情况调查,以更好地指导恶性肿瘤的防治工作。方法收集广东省肇庆市第一人民医院1984年1月至2003年12月16217例经确诊进行住院治疗的恶性肿瘤患者临床资料,就流行强度、人群分布、地理分布、发病因素、临床情况等进行调查。结果肇庆地区恶性肿瘤发病住院人数近20年来排名前5位的恶性肿瘤是:鼻咽癌5352例,占33.0%;肺癌2076例,占12.8%;食管癌1768例,占10.9%;肝癌1427例,占8.8%;乳腺癌1070例,占6.6%。男性发病10782例,占66.5%;女性发病5435例,占33.5%;城市居民发病6146例,占37.9%;农村10071例,占66.1%。发病在35～60岁年龄组8627例,占53.2%;其次是61岁以上年龄组5935例,占36.6%。结论肇庆市恶性肿瘤发病以鼻咽癌、肺癌、食管癌、肝癌、乳腺癌为多见。主要危及中壮年男性人群,应对这部分人群加强监测。     

2003-2004年乌海市肺结核病报告病人对比分析

目的:了解2003-2004年肺结核在乌海市的发病特点,针对其具体情况,制定切实可行的防治实施方案,减少肺结核的发病.方法:据2003-2004年海勃湾网络报告的肺结核,按流行病学的方法,以报告时间、地点、发病人群进行调查分析.结果:2004年报告的新发病人、复发病人、其它病人均高于2003年,报告的病人数男性多于女性.结论:乌海市肺结核报告逐年增加,三区病例数海勃湾区最多,在25～44岁之间病人数最多,男性明显高于女性.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.