生物蛋白胶防治乳腺癌术后皮下积液的研究

目的探讨医用生物蛋白胶在防治乳腺癌改良根治术后皮下积液的方法和疗效。方法将94例行乳腺癌改良根治术的患者随机分成两组,实验组应用医用生物蛋白胶组46例,对照组48例未使用医用生物蛋白胶,观察术后两组第1天引流量、总引流量及皮下积液发生的情况,并对两组进行统计分析。结果医用生物蛋白胶组术后第1天引流量为(83.2±10.9)ml,较对照组的(190.2±36.5)ml明显减少,差异具有统计学意义(P<0.05),实验组术后总引流量为(180.8±30.1)ml,明显低于未使用生物蛋白胶组的(448.1±84.2)ml,差异具有统计学意义(P<0.05),实验组皮下积液的发生率为10.87%(5/46),明显低于未使用生物蛋白胶组的33.33%(16/48)。结论医用生物蛋白腔能有效控制创面渗血、封闭淋巴管,减少创面引流量,降低皮下积液发生率,在防治乳腺癌改良根治术后皮下积液方面具有良好的临床应用价值。     

医用生物蛋白胶在防治乳腺癌术后皮下积液的临床分析

目的 观察乳腺癌改良根治术中应用医用生物蛋白胶对术后引流的影响.方法 将135例行乳腺癌改良根治术的患者随机分为两组.手术中采用医用生物蛋白胶组68例行乳腺改良根治术时在手术创面使用生物蛋白胶,未用生物蛋白胶组67例行乳腺改良根治术时未使用生物蛋白胶.比较两组术后第1天引流量,总引流量及皮下积液的情况.结果 使用生物蛋白胶组术后第1天引流量、术后总引流量及皮下积液的发生率均明显低于未使用生物蛋白胶组,P<0.05,差异有统计学意义.结论 在乳腺癌手术中应用生物蛋白胶可明显减少淋巴积液,使术后皮下积液减少,有利于创口愈合,值得临床上推广应用.     

医用生物蛋白胶在乳腺癌根治术中的应用价值

目的　探讨医用生物蛋白胶在乳腺癌根治术中的应用价值。方法　将 32例乳腺癌病人随机分成两组。用胶组 ( 15例 )行常规乳腺癌根治术同时在手术创面喷洒医用生物蛋白胶 ,未用胶组 ( 17例 )行常规乳腺癌根治术。观察两组术后第 1天引流量及总的引流量、拔管时间、术后住院日和皮下积液的情况。结果　用胶组术后第 1天引流量、总引流量以及平均拔管时间均明显少于未用胶组 (P <0 0 1) ,术后住院日明显短于未用胶组 (P <0 0 5)。结论　应用医用生物蛋白胶可有效地减少乳腺癌根治术后创面渗液 ,有利于皮瓣愈合     

纤维蛋白胶减少乳腺癌改良根治术创面渗漏的效果观察

目的探讨乳腺癌改良根治术中应用医用纤维蛋白胶(FG)对减少创面渗血的效果。方法将行乳腺癌改良根治术的72例乳腺癌患者分为两组,实验组36例术中创面使用FG,对照组36例不使用FG,观察术后第1天引流量及引流总量、拔管时间、皮下积液情况。结果实验组术后第1天引流量及引流总量、拔管时间明显少于对照组(P均<0． 01),皮下积液发生率亦少于对照组(P<0．01)。结论乳腺癌改良根治术中应用FG能有效减少创面引流量,降低皮下积液发生率,有利于切口愈合。     

医用生物蛋白胶在乳腺癌术中的应用

目的：观察乳腺癌改良根治术中应用医用生物蛋白胶对术后引流的影响。方法：将143例行乳腺癌改良根治术的患者随机分为对照组和观察组,手术中采用医用生物蛋白胶均匀喷洒在观察组创面上。对照组除术中不用生物蛋白胶外,其他步骤与观察组相同。比较两组术后引流管留置时间。结果：观察组术后3d引流量、引流管留置时间及皮下积液的发生率均明显低于对照组,P〈0．05,差异有统计学意义。结论：在乳腺癌手术中应用生物蛋白胶可明显减少术后引流管留置时间,值得临床上推广应用。     

医用生物蛋白胶与山茛菪碱预防乳腺癌术后皮下积液的作用

目的：探讨医用生物蛋白胶与山莨菪碱在预防乳腺癌术后皮下积液、皮瓣坏死等中的临床应用价值。方法：回顾性分析2004～2008年收治的60例乳腺癌患者,随机分成两组,实验组30例,对照组30例。实验组标本切除后给予止血、引流、创面喷洒医用生物蛋白胶并加压包扎,术后立即给予山莨菪碱针剂20mg加入100mL生理盐水静脉滴注。对照组切除标本后常规止血、引流、加压包扎,创面不喷洒医用生物蛋白胶,术后不给予山莨菪碱针剂滴注。结果：实验组第1天引流量及总引流量均较对照组减少,术后皮瓣坏死发生率较对照组低,拔管时间及住院时间较对照组明显减少。结论：乳腺癌治疗中应用医用生物蛋白胶和山莨菪碱。能有效减少创面渗液量,降低皮下积液及皮瓣坏死发生率,缩短拔管时间和住院天数。     

医用生物蛋白胶与山莨菪碱预防乳腺癌术后皮下积液的作用

目的：探讨医用生物蛋白胶与山莨菪碱在预防乳腺癌术后皮下积液、皮瓣坏死等中的临床应用价值。方法：回顾性分析2004～2008年收治的60例乳腺癌患者,随机分成两组,实验组30例,对照组30例。实验组标本切除后给予止血、引流、创面喷洒医用生物蛋白胶并加压包扎,术后立即给予山莨菪碱针剂20mg加入100mL生理盐水静脉滴注。对照组切除标本后常规止血、引流、加压包扎,创面不喷洒医用生物蛋白胶,术后不给予山莨菪碱针剂滴注。结果：实验组第1天引流量及总引流量均较对照组减少,术后皮瓣坏死发生率较对照组低,拔管时间及住院时间较对照组明显减少。结论：乳腺癌治疗中应用医用生物蛋白胶和山莨菪碱。能有效减少创面渗液量,降低皮下积液及皮瓣坏死发生率,缩短拔管时间和住院天数。     

生物蛋白胶在乳腺癌手术中的应用

乳腺癌根治术后通常发生皮下积液、积血、皮缘坏死，导致切口延期愈合。医用生物蛋白胶具有封闭组织缺损、止血、促进伤口愈合和生物粘合的功能，为了减少皮下积液、积血、皮缘坏死，促进切口一期愈合，我科自2004年1月-2005年12月以33例行乳腺癌保留胸大小肌改良根治术的患者为对象，随机分成两组。实验组乳腺癌改良根治术后使用医用生物蛋白胶喷洒创面及缝合切口，与对照组进行对比研究，现报告如下。[第一段]     

医用生物蛋白胶预防乳腺癌术后皮下积液效果观察

目的：评价医用生物蛋白胶预防乳腺癌术后皮下积液的应用价值。方法：将患者随机分成2组,实验组36例术中应用生物蛋白胶,对照组35例未用生物蛋白胶,观察术后第1—4d的引流量、皮下积液、皮缘坏死率及住院天数,并进行对比分析。结果：实验组术后第1～4d的引流量、皮下积液、皮缘坏死率及住院天数均明显低于对照组,两组间差别有统计学意义。结论：医用生物蛋白胶能有效地减少乳腺癌术后皮下积液、皮缘坏死率,缩短住院天数,具有良好的应用价值。     

乳腺癌改良根治术后皮下积液的预防及处理

目的探讨乳腺癌改良根治术后皮下积液的预防及处理方法。方法选取我院2012年2月—2013年2月收治的98例行改良根治术治疗的乳腺癌患者,随机将其分为观察组和对照组,各49例。给予对照组患者常规护理,观察组患者则在此基础上行皮下积液预防及护理。对2组患者的引流量、皮瓣坏死发生率、皮下积液发生率、住院时间等进行对比。结果观察组患者的引流量、皮瓣坏死发生率、皮下积液发生率、住院时间均明显优于对照组（P〈0.05）。结论在常规护理的基础上给予行改良根治术治疗的乳腺癌患者皮下积液预防及护理,可有效减少引流量,缩短患者住院时间,且有助于减少皮下积液及皮瓣坏死发生,临床效果显著,值得推广和应用。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.