三棱火针加拔罐治疗腘窝囊肿30例

ObjectiveTo explore the therapeutic effect of the fire needling with the three-edged needle and the cupping on popliteal cyst.MethodsA total of 60 patients of popliteal cyst were divided into two groups, 30 cases in each one according to the random number table. In the fire needling group, the burnt-red three-edged needle was inserted to the deep layer of the cyst. After the fluid was squeezed out, the cupping was exerted. The treatment was given 1 to 2 times a week, for 4 weeks totally. In the western medication group, prednisolone acetate 25 mg was injected in the cyst capsule, once a week, for 4 weeks totally. The effective rate, recurrence rate and Rauschning–Lindgren grading were evaluated before and after treatment.ResultsThe total effective rate was 80.0% in the fire needling group and was 83.3% in the western medication group, without statistical significance in comparison (P > 0.05). The recurrence rate was 6.7% in the fire needling group and was 30% in the western medication group. The recurrence rate in the fire needling group was lower than that in the western medication group, indicating the statistical significance (P < 0.05). After treatment, Rauschning–Lindgren grade was different statistically as compared with that before treatment in either group (both P < 0.05). Rauschning–Lindgren grade was distributed in 0 to I in the fire needling group after treatment, which was different significantly as compared with the western medication group (P < 0.05).ConclusionThe combined treatment with the fire needling combined with cupping therapy achieves the satisfactory effect on popliteal cyst and the very low recurrence rate and it is easy in operation and deserves to be promoted in primary care.     

小青龙汤加味治疗支气管哮喘外寒内饮证的疗效分析

目的:研究分析小青龙汤加味联合西药治疗支气管哮喘外寒内饮证的临床疗效,以评价小青龙汤加味对支气管哮喘外寒内饮证的改善作用。方法:将80名患者随机分为治疗组与对照组,对照组患者给予常规西药治疗(吸氧、抗炎、抗过敏、平喘等雾化吸入药物及常规口服药物治疗),治疗组在对照组治疗的基础上给予小青龙汤加味口服,疗程均为14 d,并在3个月后进行随访,分别统计2组治疗前后中医证候积分、有效率及血液因子白介素-5(IL-5)、白介素-10(IL-10)等,以进一步评价疗效。结果:治疗组较对照组中医证候积分明显降低,IL-5水平降低,IL-10水平升高,差异具有显著性(P0.05)。结论:小青龙汤加味联合西药能显著降低支气管哮喘患者的中医证候积分,改善肺功能,降低IL-5水平,提高IL-10水平,减少复发率。     

补脾泻肝法治疗腹泻型肠易激综合征临床研究

目的观察补脾泻肝法治疗腹泻型肠易激综合征的临床疗效。方法100例腹泻型肠易激综合征患者随机分为2组,治疗组60例给予白术芍药散加味,对照组40例给予丙咪嗪合替加色罗治疗。2组均4周为1个疗程,观察疗效,并于3-6个月后观察2组病例复发情况。结果治疗组治愈率为65%,总有效率为85%,6个月内复发率为20%,对照组则分别为32.5%、72.5%、55.56%,2组比较差异均有统计学意义(均P<0.05)。结论补脾泻肝法治疗腹泻型肠易激综合征优于丙咪嗪合替加色罗,疗效确切。     

急性ST段抬高型心肌梗死患者中医证型与基质金属蛋白酶-3、基质金属蛋白酶-9、基质金属蛋白酶抑制剂-1表达的关系研究

目的:观察急性ST段抬高型心肌梗死患者中医证型与MMP-3、MMP-9、TIMP-1水平的关系。方法:纳入急性ST段抬高型心肌梗死患者65例作为试验组,确定中医证型,另外选择健康体检者30例为对照组,试验组和对照组均采集静脉血检测MMP-3、MMP-9、TIMP-1表达水平。结果:试验组患者血清MMP-3为(30.63±25.14)μg·L~(-1),明显高于对照组的(13.45±6.88)μg·L~(-1)(P0.05);试验组患者血清MMP-9为(349.21±125.78)μg·L~(-1),明显高于对照组的(207.88±53.52)μg·L~(-1)(P0.05);试验组患者血清TIMP-1为(3 528.64±1 120.97)μg·L~(-1),明显高于对照组的(1749.03±803.86)μg·L~(-1)(P0.05)。心血瘀阻证患者血清MMP-3(42.51±19.61)μg·L~(-1)、MMP-9(400.17±114.80)μg·L~(-1)、TIMP-1(3902.36±1052.64)μg·L~(-1),水平明显高于其他证型患者,差异有统计学意义(P0.05)。MMP-3/TIMP-1与MMP-9/TIMP-1呈正相关(r=0.779,P=0.01 P0.05)。结论:急性ST段抬高型心肌梗死患者血清MMP-3、MMP-9、TIMP-1明显升高,且心血瘀阻证中医证候与血清MMP-3、MMP-9、TIMP-1密切相关。     

以脑氧饱和度监测为导向维护体外循环冠脉搭桥手术期间脑氧供需平衡

目的探讨脑氧饱和度(SctO2)监测在冠心病患者行体外循环冠脉搭桥术中反映脑氧供需平衡的临床应用价值。方法 10例冠心病冠脉搭桥术患者,美国麻醉师协会(ASA)II~III级,术中常规监测动脉压(MAP)、心率(HR)、脉搏血氧饱和度(SpO2)、呼气末二氧化碳分压(PetCO2)、脑电双频指数(BIS)、体温(T)、SctO2。术中以SctO2为导向进行脑氧供需平衡管理。结果体外循环期间,SctO2明显下降(P0.05),但高于基础值的75%,术后无认知功能障碍和严重神经系统并发症发生。结论体外循环冠脉搭桥术手术期间以SctO2为导向进行脑氧供需平衡管理,能够及时准确反映脑血流及氧供需平衡的变化,预防神经系统不良事件的发生。     

穴位注射法对哮喘大鼠的治疗作用

目的探讨穴位注射丹参注射液对支气管哮喘大鼠的干预作用。方法将SD大鼠24只随机分为对照组、哮喘模型组、穴位注射丹参注射液组,观察大鼠一般情况及肺组织TGF-β1含量的变化。结果哮喘组及治疗组大鼠肺组织TGF-β1含量均高于正常组;治疗组大鼠肺组织TGF-β1含量低于哮喘组,差异有显著性。结论 TGF-β1是肺纤维化形成与发展过程中关键性的细胞因子之一;穴位注射丹参注射液能够通过下调大鼠肺组织TGF-β1含量,从而降低气道高反应性、控制或延缓气道纤维化进程。     

枳实消痞丸加减治疗肠易激综合征临床体会

肠易激综合征(irritable bowel syndrome,IBS)是指一组包括持续或间歇发作的腹痛、腹胀、排便习惯和大便形状异常而又缺乏生化学和形态学可资解释的症候群.现代医学认为病因以心理因素和精神因素为主,是消化内科中常见且难治的一种疾病.在祖国医学中隶属于痞满、腹胀、呕吐等范畴,其病因多与情志失调、饮食失节、脾胃素虚等因素有关,病位主要在胃.笔者应用枳实消痞丸加减治疗肠易激综合征23例,取得较好的疗效.     

枳实消痞丸加减治疗肠易激综合征临床体会

肠易激综合征(irritable bowel syndrome,IBS)是指一组包括持续或间歇发作的腹痛、腹胀、排便习惯和大便形状异常而又缺乏生化学和形态学可资解释的症候群.现代医学认为病因以心理因素和精神因素为主,是消化内科中常见且难治的一种疾病.在祖国医学中隶属于痞满、腹胀、呕吐等范畴,其病因多与情志失调、饮食失节、脾胃素虚等因素有关,病位主要在胃.笔者应用枳实消痞丸加减治疗肠易激综合征23例,取得较好的疗效.     

小青龙汤加减治疗支气管哮喘外寒内饮证疗效分析

目的:通过西药和西药联合小青龙汤治疗支气管哮喘的疗效对比,评价小青龙汤对支气管哮喘的治疗作用。方法:将60名患者随机分为对照组和治疗组,对照组给予西药常规治疗(抗炎、抗过敏、平喘、必要时吸氧等),治疗组在西医治疗基础上辨证给予小青龙汤加减,疗程均为10d,并进行为期3个月的长期随访。在治疗前后进行外周血嗜酸性粒细胞计数(EO)、免疫球蛋白E(Ig E)检测,结合肺功能(PEF、FEV1)等评价其疗效,并采用哮喘控制问卷(ACQ)评价远期疗效。结果:治疗组各项疗效指标均优于对照组,差异具有统计学意义(P0.05)。结论:西药联合小青龙汤能显著改善支气管哮喘的临床症状及实验室检测指标,其疗效优于单纯西药组。