排序方式: 共有21条查询结果,搜索用时 15 毫秒
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Akbil Bengisu Meyer Tim Stubbemann Paula Thibeault Charlotte Staudacher Olga Niemeyer Daniela Jansen Jenny Mühlemann Barbara Doehn Jan Tabeling Christoph Nusshag Christian Hirzel Cédric Sanchez David Sökler Nieters Alexandra Lother Achim Duerschmied Daniel Schallner Nils Lieberum Jan Nikolaus August Dietrich Rieg Siegbert Falcone Valeria Hengel Hartmut Kölsch Uwe Unterwalder Nadine Hübner Ralf-Harto Jones Terry C. Suttorp Norbert Drosten Christian Warnatz Klaus Spinetti Thibaud Schefold Joerg C. Dörner Thomas Sander Leif Erik Corman Victor M. Merle Uta Kurth Florian von Bernuth Horst Meisel Christian Goffinet Christine 《Journal of clinical immunology》2022,42(6):1111-1129
Journal of Clinical Immunology - Six to 19% of critically ill COVID-19 patients display circulating auto-antibodies against type I interferons (IFN-AABs). Here, we establish a clinically applicable... 相似文献
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Cell cycle arrest and cell death correlate with the extent of ischaemia and reperfusion injury in patients following kidney transplantation – results of an observational pilot study 下载免费PDF全文
Felix C. F. Schmitt Eduardo Salgado Janina Friebe Thomas Schmoch Florian Uhle Thomas Fleming Johanna Zemva Lars Kihm Christian Nusshag Christian Morath Martin Zeier Thomas Bruckner Arianeb Mehrabi Peter P. Nawroth Markus A. Weigand Stefan Hofer Thorsten Brenner 《Transplant international》2018,31(7):751-760
A prolonged cold ischaemia time (CIT) is suspected to be associated with an increased ischaemia and reperfusion injury (IRI) resulting in an increased damage to the graft. In total, 91 patients were evaluated for a delayed graft function within 7 days after kidney transplantation (48 deceased, 43 living donors). Blood and urine samples were collected before, immediately after the operation, and 1, 3, 5, 7 and 10 days later. Plasma and/or urine levels of total keratin 18 (total K18), caspase‐cleaved keratin 18 (cc K18), the soluble receptor for advanced glycation end products (sRAGE), tissue inhibitor of metalloproteinase‐2 (TIMP‐2) and insulin‐like growth factor‐binding protein‐7 (IGFBP7) were measured. As a result of prolonged CIT and increased IRI, deceased donor transplantations were shown to suffer from a more distinct cell cycle arrest and necrotic cell death. Plasmatic total K18 and urinary TIMP‐2 and IGFBP7 were therefore demonstrated to be of value for the detection of a delayed graft function (DGF), as they improved the diagnostic performance of a routinely used clinical scoring system. Plasmatic total K18 and urinary TIMP‐2 and IGFBP7 measurements are potentially suitable for early identification of patients at high risk for a DGF following kidney transplantation from deceased or living donors. 相似文献
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