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排序方式: 共有559条查询结果,搜索用时 240 毫秒
1.
P. O. Berberat H. Ingold A. Gulbinas J. Kleeff M. W. Müller C. Gutt M. Weigand H. Friess M. W. Büchler 《Journal of gastrointestinal surgery》2007,11(7):880-887
Concepts in “fast-track” surgery, which provide optimal perioperative care, have been proven to significantly reduce complication
rates and decrease hospital stay. This study explores whether fast-track concepts can also be safely applied and improve the
outcomes of major pancreatic resections. Perioperative data from 255 consecutive patients, who underwent pancreatic resection
by means of fast-track surgery in a high-volume medical center, were analyzed using univariate and multivariate models. Of
the 255 patients, 180 received a pancreatic head resection and 51 received distal, 15 received total, and 9 received segmental
pancreatectomies. The patients were discharged on median day 10 with a 30-day readmission rate of 3.5%. The in-hospital mortality
was 2%, whereas medical and surgical morbidities were 17 and 25%, respectively. Fast-track parameters, such as first stools,
normal food, complete mobilization, and return to normal ward, correlated significantly with early discharge (p < 0.05). Patients’ age, operation time, and early extubation proved to be independent factors of early discharge, shown through
multivariate analysis (odds ratio: 4.0, 2.0, and 2.8, respectively; p < 0.05). Low readmission, mortality, and morbidity rates demonstrate that fast-track surgery is in fact feasible and safe
and promotes earlier discharge without compromising patient outcomes. 相似文献
2.
This article describes an operational method for the temporary protection of the anterior cruciate ligament after acute or late ligament reconstruction. In line with the course of the anterior cruciate ligament a wire rope is transarticularly implanted and fixed with a screw each at the femur (proximally) and at the tibia bone (distally). This easily performed method permits both the healing of the ligament lesion while preserving the original ligament length and the execution of an early functional exercise therapy. 相似文献
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The possibility of reducing the number of animals in sensitization studies (maximization method) is discussed on the basis of results from 20 sensitization tests. It appears that the number of test animals in sensitization studies may be reduced to ten treated animals and five control animals without prejudice to the quality of the test. 相似文献
5.
Kurt Weising Dieter Kaemmer Jörg T. Epplen Franz Weigand Mohan Saxena Günter Kahl 《Current genetics》1991,19(6):483-489
Summary The ascomycete fungus Ascochyta rabiei, an important pathogen of the grain legume crop chickpea (Cicer arietinum L.) in the Mediterranean region, has not been adequately characterized in molecular terms. We therefore used DNA fingerprinting, with synthetic oligodeoxynucleotides complementary to simple repetitive sequences, to pathotype different isolates of the fungus. Six single-spored A. rabiei isolates were first categorized using a host differential set of nine chickpea genotypes. Seedlings were inoculated under controlled environmental conditions, and disease severity was recorded 9 days after inoculation. DNA was extracted from in vitro-grown mycelia of the six purified fungal isolates, restricted with EcoRI, HinfI, MboII and TaqI, and fingerprinted with radiolabeled (GATA)4, (GTG)5, (CA)8, and (TCC)5, respectively. High levels of polymorphism were detected with optimal enzyme/probe combinations that allow one to discriminate between the isolates. The potential of DNA fingerprinting with simple repetitive sequences can thus be expanded to the identification of fungal races and pathotypes. The characterization of the geographic distribution and genetic variability of pathotypes will facilitate the selection of suitable host cultivars to be grown in specific regions. 相似文献
6.
Mechanism of antimicrobial activity of essential oils 总被引:1,自引:0,他引:1
7.
Point-of-care measured serum cholinesterase activity predicts patient outcome following severe burns
Karsten Schmidt Aleksandar R. Zivkovic Martin Thiele Johannes Horter Thorsten Brenner Markus A. Weigand Stefan Kleinschmidt Stefan Hofer 《Burns : journal of the International Society for Burn Injuries》2021,47(4):863-872
Risk stratification is of utmost importance in burn therapy. However, suitable bedside biomarkers to evaluate the emerging inflammatory response following burn injuries are missing. Serum cholinesterase (butyrylcholinesterase, BChE) has been shown to be a clinically relevant biomarker in acute inflammatory diseases including burns.In this observational cohort study BChE activity was measured by using point-of-care testing (POCT), a novel method in acute burn care. POCT measurements were performed at emergency room admission (ERA) of 35 patients and repeated 12, 24 and 48 h later. All patients or their legal designees gave informed consent.Patients with burn injuries showed sustained BChE activity reduction following hospital admission. BChE activity correlated negatively with burn injury severity, organ failure severity and intensive care unit resource requirements. BChE activity measured at ERA and 12 h later identified survivors and predicted 28-day patient outcome with noninferior efficacy compared to the abbreviated burn severity index (ABSI) scoring. Finally, POCT-measured BChE activity might complement ABSI scoring and possibly improve early risk stratification in acute burn care therapy. 相似文献
8.
Die Anaesthesiologie - 相似文献
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Siegler Benedikt Hermann Oehler Beatrice Kranke Peter Weigand Markus Alexander 《Der Anaesthesist》2022,71(8):646-660
Die Anaesthesiologie - Der Postpunktionskopfschmerz („postdural puncture headache“, PDPH) zählt zu den wesentlichen Komplikationen der peripartalen neuroaxialen Analgesie. Als... 相似文献