全文获取类型
收费全文 | 639276篇 |
免费 | 43309篇 |
国内免费 | 840篇 |
专业分类
耳鼻咽喉 | 8116篇 |
儿科学 | 20459篇 |
妇产科学 | 16206篇 |
基础医学 | 104595篇 |
口腔科学 | 17925篇 |
临床医学 | 54985篇 |
内科学 | 118299篇 |
皮肤病学 | 14300篇 |
神经病学 | 48793篇 |
特种医学 | 23818篇 |
外国民族医学 | 83篇 |
外科学 | 93311篇 |
综合类 | 8974篇 |
现状与发展 | 1篇 |
一般理论 | 235篇 |
预防医学 | 52964篇 |
眼科学 | 14210篇 |
药学 | 48330篇 |
中国医学 | 1196篇 |
肿瘤学 | 36625篇 |
出版年
2019年 | 5458篇 |
2018年 | 7491篇 |
2017年 | 5803篇 |
2016年 | 6507篇 |
2015年 | 7170篇 |
2014年 | 9781篇 |
2013年 | 14396篇 |
2012年 | 20305篇 |
2011年 | 21748篇 |
2010年 | 12277篇 |
2009年 | 11895篇 |
2008年 | 20374篇 |
2007年 | 21600篇 |
2006年 | 21607篇 |
2005年 | 20700篇 |
2004年 | 19514篇 |
2003年 | 18568篇 |
2002年 | 17907篇 |
2001年 | 28356篇 |
2000年 | 29395篇 |
1999年 | 24374篇 |
1998年 | 6668篇 |
1997年 | 5646篇 |
1996年 | 6044篇 |
1995年 | 5773篇 |
1994年 | 5378篇 |
1993年 | 5125篇 |
1992年 | 18485篇 |
1991年 | 18847篇 |
1990年 | 18877篇 |
1989年 | 18091篇 |
1988年 | 16699篇 |
1987年 | 16290篇 |
1986年 | 15366篇 |
1985年 | 14677篇 |
1984年 | 10821篇 |
1983年 | 9275篇 |
1979年 | 10319篇 |
1978年 | 7374篇 |
1977年 | 6236篇 |
1976年 | 5954篇 |
1975年 | 6821篇 |
1974年 | 8117篇 |
1973年 | 7612篇 |
1972年 | 7431篇 |
1971年 | 7129篇 |
1970年 | 6520篇 |
1969年 | 6220篇 |
1968年 | 5905篇 |
1967年 | 5258篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Lykov A. P. Uvarov I. P. Gevorgiz R. G. Zheleznova S. N. 《Bulletin of experimental biology and medicine》2022,172(3):301-304
Bulletin of Experimental Biology and Medicine - We studied the effect of microalgae of various systematic groups added to the ration on the biochemical parameters of blood serum and liver and... 相似文献
2.
3.
Gordon K. B. Saburov V. O. Koryakin S. N. Gulidov I. A. Fatkhudinov T. Kh. Arutyunyan I. V. Kaprin A. D. Solov’ev A. N. 《Bulletin of experimental biology and medicine》2022,173(2):281-285
Bulletin of Experimental Biology and Medicine - Fast neutron therapy, which previously has demonstrated effective results, but along with a large number of complications, can again be considered a... 相似文献
4.
Zyuz’kov G. N. Zhdanov V. V. Miroshnichenko L. A. Polyakova T. Yu. Stavrova L. A. Simanina E. V. Minakova M. Yu. Agafonov V. I. Churin A. A. 《Bulletin of experimental biology and medicine》2022,173(5):615-619
Bulletin of Experimental Biology and Medicine - The psychopharmacological effects of a stimulator of functions of progenitor cells of the nervous tissue STAT3 inhibitor (STAT3 Inhibitor XIV, LLL12)... 相似文献
5.
6.
Improving hyperpolarized 129Xe ADC mapping in pediatric and adult lungs with uncertainty propagation
7.
Yevdulov O. V. Yevdulov D. V. Isabekova T. I. Aminov G. I. Aminova I. Yu. 《Biomedical engineering》2022,56(2):146-150
Biomedical Engineering - A mathematical model of a thermoelectric device for the treatment of whitlow by local hypothermia is discussed. The model is based on a solution of the heat conduction task... 相似文献
8.
Cynthia S. E. Hendrikse MD Phyllis van der Ploeg MD PhD Nienke M. A. van de Kruis MD Jody H. C. Wilting MD Floor Oosterkamp BSc Pauline M. M. Theelen MSc Christianne A. R. Lok MD PhD Joanne A. de Hullu MD PhD Huberdina P. M. Smedts MD PhD M. Caroline Vos MD PhD Brenda M. Pijlman MD Loes F. S. Kooreman MD Johan Bulten MD PhD Marjolein H. F. M. Lentjes-Beer MD PhD Steven L. Bosch MD PhD Anja van de Stolpe MD PhD Sandrina Lambrechts MD PhD Ruud L. M. Bekkers MD PhD Jurgen M. J. Piek MD PhD 《Cancer》2023,129(9):1361-1371
Background
Advanced low-grade ovarian carcinoma (LGOC) is difficult to treat. In several studies, high estrogen receptor (ER) protein expression was observed in patients with LGOC, which suggests that antihormonal therapy (AHT) is a treatment option. However, only a subgroup of patients respond to AHT, and this response cannot be adequately predicted by currently used immunohistochemistry (IHC). A possible explanation is that IHC only takes the ligand, but not the activity, of the whole signal transduction pathway (STP) into account. Therefore, in this study, the authors assessed whether functional STP activity can be an alternative tool to predict response to AHT in LGOC.Methods
Tumor tissue samples were obtained from patients with primary or recurrent LGOC who subsequently received AHT. Histoscores of ER and progesterone receptor (PR) were determined. In addition, STP activity of the ER STP and of six other STPs known to play a role in ovarian cancer was assessed and compared with the STP activity of healthy postmenopausal fallopian tube epithelium.Results
Patients who had normal ER STP activity had a progression-free survival (PFS) of 16.1 months. This was significantly shorter in patients who had low and very high ER STP activity, with a median PFS of 6.0 and 2.1 months, respectively (p < .001). Unlike ER histoscores, PR histoscores were strongly correlated to the ER STP activity and thus to PFS.Conclusions
Aberrant low and very high functional ER STP activity and low PR histoscores in patients with LGOC indicate decreased response to AHT. ER IHC is not representative of functional ER STP activity and is not related to PFS. 相似文献9.
Marie V. Plaisime PhD MPH Marie Jipguep-Akhtar PhD Joseph J. Locascio PhD Harolyn M. E. Belcher MD MHS Rachel R. Hardeman PhD MPH Katherine Picho-Kiroga PhD Sylvia P. Perry PhD Sean M. Phelan PhD MPH Michelle van Ryn PhD LMFT MPH John F. Dovidio PhD 《Health services research》2023,58(Z2):229-237
Objective
To examine the experience of interracial anxiety among health professionals and how it may affect the quality of their interactions with patients from racially marginalized populations. We explored the influence of prior interracial exposure—specifically through childhood neighborhoods, college student bodies, and friend groups—on interracial anxiety among medical students and residents. We also examined whether levels of interracial anxiety change from medical school through residency.Data Source
Web-based longitudinal survey data from the Medical Student Cognitive Habits and Growth Evaluation Study.Study Design
We used a retrospective longitudinal design with four observations for each trainee. The study population consisted of non-Black US medical trainees surveyed in their 1st and 4th years of medical school and 2nd and 3rd years of residency. Mixed effects longitudinal models were used to assess predictors of interracial anxiety and assess changes in interracial anxiety scores over time.Principal Findings
In total, 3155 non-Black medical trainees were followed for 7 years. Seventy-eight percent grew up in predominantly White neighborhoods. Living in predominantly White neighborhoods and having less racially diverse friends were associated with higher levels of interracial anxiety among medical trainees. Trainees' interracial anxiety scores did not substantially change over time; interracial anxiety was highest in the 1st year of medical school, lowest in the 4th year, and increased slightly during residency.Conclusions
Neighborhood and friend group composition had independent effects on interracial anxiety, indicating that premedical racial socialization may affect medical trainees' preparedness to interact effectively with diverse patient populations. Additionally, the lack of substantial change in interracial anxiety throughout medical training suggests the importance of providing curricular tools and structure (e.g., instituting interracial cooperative learning activities) to foster the development of healthy interracial relationships. 相似文献10.