Humoral and Cellular Responses to Influenza Vaccination in Human Recipients Naturally Tolerant to a Kidney Allograft

Rare kidney allograft recipients enjoy unaltered graft function years after interruption of their immunosuppressive treatment. To assess the extent to which this state of 'operational tolerance' (TOL) is specific to the graft and not the result of a global immunodeficiency, we analyzed the response of such patients following influenza vaccination. Hemagglutination inhibition titers and frequency of IFNgamma-secreting T cells were measured before 1 and 3 months after vaccination. The proportion of healthy volunteers (HV) responding to vaccine was significantly higher than that of immunosuppressed (IS) patients. Three 'TOL' patients presented a humoral response similar to that of HV, whereas the two others had a poor response, like the IS recipients. Although the small number of patients does not allow for definitive conclusions to be made, these data suggest that the status of tolerance may be heterogeneous, with some patients with a global immunodeficiency and others with an adapted response to vaccination.     

大型尿基复合肥养分偏差的原因分析及措施

介绍大型尿基复合肥装置在生产中引起产品养分偏差的原因及采取的操作措施。     

基于美军二战海战减员数据的校正

目的：通过对二战减员数据的校正，为下一步建立海战减员预计模型提供数据支持．方法：选取美军在二战太平洋海战中的减员数据作为研究的基本资料，通过专家咨询法(Delph method)对其进行校正，所有结果都对其进行了t检验．结果：水面舰艇遭受炸弹、舰炮及航空火炮、短程导弹、鱼雷和水雷的攻击时减员将减少，遭受中程导弹攻击时减员将会增加．结论：该校正结果可作为研究未来海战卫生减员预计的基本依据之一．     

海勤人员战伤救护知识培训现状调查

目的 了解海勤人员战伤救护知识培训现状,为进一步系统有效地开展培训提供依据.方法 根据海勤人员的工作环境、战备训练及现代海战伤救治特点和规律自行设计问卷,对潜艇艇员、潜水员共计217人进行调杳.结果 特殊伤现场救护和心理应激渊适培训在潜艇艇员和潜水员之间差异有统计学意义(P<0.05).特殊武器伤现场救护培训内容中的生物武器伤和化学武器伤救护知识的培训,在潜艇艇员和潜水员之间差异无统计学意义(P>0.05);对核武器伤和新概念武器伤救护知识的培训,在潜艇艇员和潜水员之间差异有统计学意义(P<0.05).结论 战伤救护知识的培洲已在海勤部队开展,自救瓦救6项技术培训较好,新概念武器伤和特殊伤救护知识的培训开展较差.心理应激调适知识培训欠缺.     

Optimal control problems with Atangana‐Baleanu fractional derivative

In this paper, we study fractional‐order optimal control problems (FOCPs) involving the Atangana‐Baleanu fractional derivative. A computational method based on B‐spline polynomials and their operational matrix of Atangana‐Baleanu fractional integration is proposed for the numerical solution of this class of problems. With this numerical technique, the FOCPs are reduced to a system of equations which are solved for the unknown parameters with the help of Mathematica® software. Our results show the applicability and usefulness of the numerical technique.     

新型高级创伤外科机动救治力量及其培训体系的建立

未来远海环境下的舰艇编队作战将成为我海军主要作战形式。远海作战战场广阔、攻防形势转换快、所致伤情伤势复杂,易在任意时间、任意战场地点瞬间产生批量伤员,救治难度极大。本文系统介绍了一种针对远海舰艇编队作战的新型高级创伤外科机动救治队伍及其专属模块化、标准化、轻量化的手术复苏装备系统,并阐述其培训体系构想,以备卫勤研究者、参与者借鉴参考。     

医院信息系统的运行管理

医院信息系统应用后 ,做好系统的运行管理和维护工作 ,是管好、用好系统的关键。本文就系统运行管理的基本目的、系统运行管理的组织与实施及系统运行管理的主要内容进行了探讨     

提高中药粉粒体蒸汽灭菌的效率和节能探讨

介绍一种利用单锥真空干燥机进行中药材蒸汽灭菌,既可避免料盘式蒸汽灭菌箱的手工装卸料盘的操作性污染,又可提高灭菌工作效率和节省能耗。     

Operational research leading to rapid national policy change: tuberculosis-diabetes collaboration in India

In 2011, bi-directional screening for tuberculosis (TB) and diabetes mellitus (DM) was recommended by the World Health Organization (WHO), although how best to implement the activity was not clear. In India, with early engagement of national programme managers and all important stakeholders, a countrywide, multicentre operational research (OR) project was designed in October 2011 and completed in 2012. The results led to a rapid national policy decision to routinely screen all TB patients for DM in September 2012. The process, experience and enablers of implementing this unique and successful collaborative model of operational research are presented.