尿素霜的处方改进

目的:改进尿素霜处方,提高其质量和储存稳定性。方法:作影响因素的均匀设计试验,并根据试验结果设计新处方。结果:设计了最佳处方,新处方成品质量和稳定性明显优于原处方。结论:新处方是对原处方的成功改进。     

脂肪乳剂对食管癌术后细胞因子和免疫功能的影响

目的：本研究探讨脂肪乳剂对食管癌术后炎症反应和免疫功能的影响。方法：采用前瞻性、随机、对照设计，将33例食管癌切除术病人随机分成2组，A组(15例)为对照组接受不含脂肪乳剂的肠外营养，B组(18例)接受含有脂肪乳剂的肠外营养。2组病人的一般临床情况、非蛋白热量分布一致。分别于术前术后不同时段测定血清中IL—6、IL—10浓度、T细胞亚群和NK细胞活性。结果：术后1、3天两组血清IL—6水平均显升高，且B组显高于A组。血清IL—10与IL—6变化相似。术后3天血清IL-6浓度与IL—10浓度显正相关。术后血清IL—6／IL—10比值显升高，术后7天B组显高于A组。术后CD4^ /CD8^ ,NK细胞活性均显降低，术后10天B组CD4^ /CD8^ 比值显低于A组。术后3天CD4^ /CD8^ 比值与术后1天IL—6水平显正相关。结论：高应激病人输注脂肪乳剂能增加细胞因子产生并促进免疫抑制。     

茶油对大鼠血脂及血液流变性的影响

本文研究富含油酸的茶油对大鼠的血脂和血液流变性的影响。Wistar雄性大鼠60只．分别饲养基础饲料、高脂茶油饲料和高脂猪油饲料。结果表明，茶油组血清甘油三酯（TG）明显低于基础组和猪油组，血清胆固醇（TC）亦明显低于猪油组。同样对血清低密度脂蛋白胆固醇（LDL－C）水平的影响．猪油组明显高于基础组，而茶油组与基础组未显示差异有显著性。HDL-C／TC（HDL-C指血清高密度脂蛋白胆固醇）是猪油组明显低于基础组，茶油组与基础组差异无显著性．这说明茶油对HDL-C无影响。茶油组的血小板聚集率（1’）和红细胞交形指数与基础组无差别，均明显低于猪油组的。结果说明茶油具有降低血脂和心血管疾病发生的作用。     

富集法检测三维鱼肝油乳的酵母菌

目的建立一种能有效检出三维鱼肝油乳中酵母菌的方法。方法富集法即增菌法,样品液先在合适的培养基中进行增菌培养后,再按中国药典(2005)版二部附录ⅪJ微生物限度检查项下用平皿法倒碟进行检测。结果被酵母菌污染的三维鱼肝油乳样品用富集法均能检出。结论富集法比平皿法可以更有效地检测出样品中的酵母菌,保证产品质量。     

Cinnamon bark oil, a potent fungitoxicant against fungi causing respiratory tract mycoses

Cinnamic aldehyde has been identified as the active fungitoxic constituent of cinnamon ( Cinnamomum zeylanicum ) bark oil. The fungitoxic properties of the vapours of the oil/active constituent against fungi involved in respiratory tract mycoses, i.e., Aspergillus niger, A. fumigatus, A. nidulans, A. flavus, Candida albicans, C. tropicalls, C. pseudotropicalis , and Histoplasma capsulatum , were determined in vitro as minimum inhibitory concentration (MIC), minimum lethal concentration (MLC), inoculum density sustained, and exposure duration for fungicidal action at MIC and higher doses, as well as effect of incubation temperatures on fungitoxicity. It is concluded that these inhalable vapours appear to approach the ideal chemotherapy for respiratory tract mycoses.     

不同萃取方法对番茄籽油理化性质与脂肪酸含量的影响

分别采用超临界ＣＯ２萃取技术和传统溶剂法从番茄籽中萃取脂肪油，经过甲酯化处理后，用气相色谱法分析出亚油酸等５种脂肪酸占总脂肪酸的９８．５％．同时对油的其它理化指标进行了测定。对测定结果进行了比较分析，说明超临界ＣＯ２萃取所得番茄籽油品质更好。并对番茄籽油的营养学机理作了讨论。     

茶油延缓动脉粥样硬化形成及其机理的探讨

本文报告了富含单不饱和脂肪酸（ＭＵＦＡ）的茶油对动脉粥样硬化（ＡＳ）形成及脂质代谢、血栓素Ｂ２（ＴＸＢ２）和脂质过氧化物（ＬＰＯ）的影响。结果提示，茶油具有明显的延缓ＡＳ形成的作用；其机理可能是茶油中富含的ＭＵＦＡ纳入组织后，通过降低血脂、肝脂，升高ＨＤＬ一Ｃ／ＴＣ比值，抑制ＴＸＢ２释放，增加机体抗氧化酶ＳＯＤ和ＧＳＨ一Ｐｘ的活性，降低血浆、肝脏ＬＰＯ生成等环节而发挥作用。因此，我国特产的茶油对防治冠心病（ＣＨＤ）有益，值得开发利用。     

红毛五加茎皮挥发油成分对体外培养人白血病粒细胞生物学效应的研究

报告红毛五加茎皮挥发油成分对体外培养人白血病粒细胞的生物学效应研究。药物作用癌细胞后，其生长受到明显抑制，流式细胞分光光度计测定提示，该药抑制癌细胞合成ＤＮＡ的各期，阻断了ＤＮＡ的合成。     

Separation and determination of chemical constituents in the volatile oil of three traditional Chinese crude drugs

The parts of Jilin ginseng growing on the ground, Radix aucklandiae and the citrus tangerina peels were extracted with ether, and yellow volatile oil 0.31 wt.%, 2.1 wt.% and 1.6 wt.% were obtained respectively. Their chemical constituents were separated and determined by gas chromatography and interfaced with mass spectrometry in an electron impact mode.     

Cytostatic activity against HEp-2 cells and antibacterial activity of essential oil from Helichrysum picardii

Different samples of essential oil from Helichrysum picardii Boiss. & Reuter (Compositae) collected at the beginning of each season from the same locality have been tested for their cytostatic and antimicrobial activity. All the oil samples showed a stronger in vitro activity against HEp-2 cells than a 6-mercaptopurine solution used as a positive control. Gram-positive bacteria as well as the fungus Candida albicans were sensitive to the action of the essential oil, whereas none of the samples showed activity against the gram-negative bacteria.