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21.
22.
《Presse medicale (Paris, France : 1983)》2020,49(4):104055
Complications associated with tattoos are mostly of cutaneous origin. They include chiefly ink allergy, local infection, benign tumors or malignant lesions and elective localization of various dermatoses. Tattoo-related systemic diseases and infections have more rarely been described, the most common being sarcoidosis and hepatitis C. However, unusual associations have also been reported, even though they may be anecdotal or likely unrelated with the procedure. 相似文献
23.
《Reumatología clinica》2022,18(5):253-259
ObjectivesTo describe the methods of the Spanish Registry of patients with idiopathic inflammatory myopathy (IIM) (Myo-Spain), as well as its strengths and limitations. The main objective of the project is to analyse the evolution and clinical management of a cohort of patients with IIM.MethodsObservational, longitudinal, ambispective and multicentre study of a cohort of patients with IIM seen in rheumatology units in Spain. All patients with a diagnosis of IMM will be included in the regular follow-up of the participating centres, regardless of age on initiation of the process. Incident cases will be all patients who at the beginning of the study have been diagnosed for less than 12 months and prevalent cases for more than 12 months. The registry will include data from the visit at baseline, one year and two years. Socio-demographic, clinical, analytical variables, complications, comorbidities, association with other rheumatic diseases, hospital admissions, mortality and treatments will be collected. In addition, indices, scales and questionnaires of activity, muscle involvement, damage, disability, and quality of life will be determined. The recruitment period will be 23 months. The purpose is to obtain a cohort of 400 patients with IMM.ConclusionsMyo-Spain registry provides the opportunity to develop a cohort of incident and prevalent patients with IMM in Spain. Myo-Spain will be able to assess in detail the clinical characteristics of the disease at different times. The comprehensive information collected during the visits is expected to provide a broad source of data for future analysis. 相似文献
24.
Fang Chen Shanshan Li Tao Wang Jingli Shi Guochun Wang 《The American journal of the medical sciences》2018,355(1):48-53
Background
The aim of this study was to compare the heterogeneity of interstitial lung disease (ILD) in patients with polymyositis and dermatomyositis (PM/DM) according to serological type.Methods
A total of 182 patients with PM/DM-ILD were observed retrospectively. Antiaminoacyl-tRNA synthetase (ARS) and antimelanoma differentiation-associated gene5 (MDA5) antibodies were screened using immunoblotting approach. The patients with ILD were divided into 3 groups: MDA5 (with anti-MDA5 antibody), ARS (with anti-ARS antibody) and MSN (without anti-MDA5 or anti-ARS antibody) group. Pulmonary features, treatment responses and prognoses were compared among the groups.Results
A higher percentage of rapidly progressive ILD (RP-ILD) occurrences (55.8% versus 25% versus 16.9%, P < 0.001) was observed in the MDA5 group compared to ARS and MSN groups. The MSN group experienced lower dyspnea (48.2% versus 79% versus 71.4%, P = 0.001) and fever (18.1% versus 39.5% versus 37.5%, P = 0.01) frequencies compared to MDA5 and ARS groups. Response to 6-month treatment among 95 patients showed highest deterioration ratio (70%, P = 0.001) of ILD in the MDA5 group. Additionally, the highest frequency of ILD improvement (60%, P = 0.04) was observed in the ARS group. During the observation period, 24 patients died of respiratory failure. The 5-year survival rates were significantly lower in MDA5 group (50.2%) compared to ARS group (97.7%) or the MSN group (91.4%) (P < 0.001).Conclusions
MDA5-ILD was associated with severe pulmonary manifestations, poor response to treatment and aggravated prognosis. The ARS-ILD group had favorable treatment response and prognosis. MSN-ILD patients had relatively worse treatment response and prognosis compared to the ARS group, even though they expressed milder pulmonary manifestation. 相似文献25.
27.
Dong Yeon Lee Tae-Joon Cho Hye Ran Lee Moon Seok Park Won Joon Yoo Chin Youb Chung In Ho Choi 《Journal of Korean medical science》2009,24(3):433-437
Fibrodysplasia ossificans progressiva (FOP; OMIM 135100) is a rare but extremely disabling genetic disorder of the skeletal system, and is characterized by the progressive development of ectopic ossification of skeletal muscles and subsequent joint ankylosis. The c.617G>A; p.R206H point mutation in the activin A type I receptor (ACVR1) gene has been reported to be a causative mutation of FOP. In the present study, mutation analysis of the ACVR1 gene was performed in 12 patients diagnosed or suspected to have FOP. All patients tested had a de novo heterozygous point mutation of c.617G>A; p.R206H in ACVR1. Mutation analysis confirmed a diagnosis of FOP in patients with ambiguous features, and thus, could be used for diagnostic purposes. Early confirmation through mutation analysis would allow medical professionals to advise on the avoidance of provoking events to delay catastrophic flare-ups of ectopic ossifications. 相似文献
28.
进行性骨化性肌炎1例报告并文献复习 总被引:4,自引:0,他引:4
目的 探讨进行性骨化性肌炎的临床特征和诊断要点。方法 报告1例进行性骨化性肌炎病例。结合文献,分析该疾病的临床特征,总结诊断要点和鉴别诊断。结果 进行性骨化性肌炎临床上极为罕见,其特征表现为对称性拇趾(指)畸形和进行性发展的软组织异住骨化。手术、外伤可加速病程进展。实验室检查通常正常。目前尚无有效治疗方法。结论 进行性骨化性肌炎的诊断依赖于其渐进性的病程特点和典型畸形及相应的影像学改变。应尽量避免手术、外伤等诱发因素。 相似文献
29.
Extraskeletal osteosarcoma arising in myositis ossificans 总被引:5,自引:0,他引:5
A 53-year-old woman had extraskeletal osteosarcoma that developed from a soft tissue bony mass present on the volar aspect
of the left wrist for 4 years. Initially, the bony mass was soft and movable, but during the first year it became hard and
fixed. The patient had no history of trauma. Because the lesion did not grow or cause any symptoms, the patient did not come
to the hospital until 4 years after she first noticed the lesion. Radiologically, the bony mass had features characteristic
of mature myositis ossificans, showing ”eggshell” ossification. A nonmineralized soft tissue mass occurred between the surface
of the radius and the bony shell. Histologically, a high-grade osteosarcoma was present between the surface of the radius
and the well-differentiated bone tissue, which included fatty and hematopoietic marrow. All the findings indicated that our
patient had an extremely rare case of malignant transformation of myositis ossificans.
Received: 22 June 2000 Revision requested: 2 August 2000 Revision received: 14 September 2000 Accepted: 25 September 2000 相似文献
30.
A 12-year-old boy presented with a limp and findings suggesting localised myositis of his right calf and a working diagnosis of Behçet disease was made. During 3 years of follow-up, he had another three episodes of calf myositis, all responsive to corticosteroids within days. Conclusion A case of recurrent localised myositis as a main manifestation of Behçet disease is reported. The evolution of incomplete Behçet disease, which is common in children, to the full blown form, with the emphasis on muscle involvement and the importance of early diagnosis of Behçet disease, is discussed. 相似文献