旋毛虫病免疫机理的研究现状

旋毛虫病是由旋毛虫引起的一种人、兽共患寄生虫病。在食肉哺乳动物之间广泛传播，人因食用含活旋毛虫的猪、狗、野猪、熊肉及其肉制品等而感染。随着对旋毛虫病研究的逐渐深入，人们对旋毛虫病免疫机理的研究越来越重视，已取得了一些成果，现就旋毛虫病免疫机理的研究现状介绍如下。     

雏风精对小鼠免疫功能的影响

雏风精对小鼠免疫功能的影响曲迅，李淑贞，赵温利指导：崔正言（山东省医学科学院基础所免疫室）正常小鼠肌肉注射环磷酰胺（ＣＴＸ）或醋酸氢化泼尼松（ＨＰＡ）造成免疫低下模型，通过巨噬细胞（ＭΦ）吞噬功能试验，淋巴器官重量测定，外周血淋巴细胞ａ一醋酸萘酯酶染...     

病毒性肝炎红细胞免疫功能的动态观察及其临床意义

本文报导各类型病毒性肝炎66例(临床分型为急性肝炎22例,慢迁肝22例,慢活肝15例,肝硬化7例。病原学分型:急性肝炎22例中有“甲型”9例,“乙型”10例,“丙型”3例;慢性肝病44例中均为“乙型”,其中3例重叠丙型肝炎病毒感染)和正常成人30例作红细胞C3b受体花环率和免疫复合物花环率的动态观察,结果表明,红细胞C3b受体花环率入出院时的比较,只有急性肝炎恢复至正常人水平,其余各类型肝炎无论入院时与出院时均显著低于正常人(P<0.01)。红细胞免疫复合物花环率也仅急性肝炎恢复至正常人水平,自其余各类型肝炎出入院时均显著高于正常人(P<0.01),说明红细胞免疫粘附功能在急性肝炎呈一过性损害,而慢性肝病呈持续低下状态。急性肝炎中甲、乙、丙三型对比,红细胞免疫C3b受体花环率的动态变化无显著差异,说明三者对红细胞免疫均有一定的影响。     

重症联合免疫缺陷病伴造血机能障碍：1例尸检报告及文献复习

文本报告了1例在国内较少见的重症联合免疫缺陷病伴严重造血机能障碍的尸检材料,并对国内目前已报告的同种病例进行文献复习和比较,总结了该例的病理及临床特征。     

升血汤促进小鼠免疫功能的实验研究

利用多种免疫学方法研究了中药升血汤对小鼠免疫功能的影响。结果证明，升血汤对正常小鼠的细胞免疫功能和体液免疫功能确有明显的促进作用。表现为，非特异地（多克隆）增强Ｔ、Ｂ淋巴细胞对丝裂原的增殖反应；特异地增强Ｔ细胞对异型抗原的ＭＬＲ、ＤＴＨ反应；特异地增强小鼠对ＳＲＢＣ的抗体反应；明显增强小鼠脾细胞产生ＩＬＤ２的能力。     

蒙,汉族儿童少年PHA皮试反应的观察

采用ＰＨＡ皮试反应法，对不同年龄段蒙、汉族儿童少年细胞免疫功能进行检测。皮肤红晕和硬结大小、蒙、汉族各年龄段均有明显差异，并呈随年龄增长而有增大趋势。     

肾病综合征细胞免疫研究概况

本文从免疫学角度介绍了肾病综合征的免疫遗传背景，并阐述了淋巴细胞、细胞因子及肾脏固有细胞等因素的致病作用和病理意义。     

强化精氨酸肠内营养对烧伤患者营养状况和细胞免疫的影响

Objective To investigate the effects of arginine enriched enteral nutrition (EN) on nu-tritional status and cellular immunity of severely burned patients. Methods Randomized, single blind, parallel and positive control investigation was employed in the study. Thirty severely burned patients were di-vided into enteral immune nutrition (EIN) group and EN group. Sixteen patients in EIN group received en-teral nutrition enriched with arginine, while the other 14 patients in EN group received standard enteral nu-trition. Nutritional support was continued for 14 days. Gastrointestinal reaction of patients in 2 groups was observed. Fasting venous blood was drawn from patients of both groups before receiving nutrition treatment and on the morning of 7th, 14th day of treatment. Level of serum protein, hepatic function parameters, renal function parameters, fasting-blood glucose, and subpopulations of T lymphocytes in peripheral blood were determined. Results (1) Incidence of gastrointestinal side effect in EIN group (25.0%) was close to that of EN group (21.4% , P>0.05). (2) Compared with pre-treatment days, levels of prealbumin and transferrin in serum of patients in 2 groups on 7th and 14th post-treatment days were significantly increased (P<0.05 or P<0.01), but there was no significant difference between 2 groups. The level of total serum protein on 14th day of treatment of patients was significantly increased in both groups, and that of EIN group (66±7 g/L)was significantly higher compared with that in EN group (64 ± 11 g/L, P<0.05). The level of serum albumin (29±5, 32±5 g/L, respectively) of patients in EIN group on 7th and 14th day of treat-ment were significantly higher than that (26±4 g/L, P <0.05) in pre-treatment days, however there was no significant difference in EN group. (3) There was no significant difference in respect of hepatic function, renal function, and fasting-blood glucose between pre-treatment and post-treatment periods in both groups (P>0.05). (4) The ratio of CD4+ , CD8+ on 14th day of treatment in EIN group was close to that of pre-treatment level. In EN group, cell percentage of CD4+ significantly decreased, while that of CD8+ significantly increased (P<0.05), and CD4+ was significantly higher [(56±8) %] in EIN group than that in EN group [(55±12) % , P <0.05]. In both groups, cell percentage of CD3+ was significantly higher than that in pre-treatment days (P<0.05), while there was no obvious change in CD4+/CD8+. Conclusions Arginine enriched enteral nutrition can effectively improve nutritional status and cellular immune function of burn patients.     

健脾益肾方改善维持血液透析患者细胞免疫的疗效评价

目的:观察中药健脾益肾方对尿毒症维持血透患者细胞免疫的影响.方法:将65例尿毒症维持血透患者随机分为两组,两组均给予每周3次血透治疗,治疗组予口服健脾益肾方,对照组予口服安慰剂.疗程3个月,治疗前后检测CD3+、CD4+、CD8+、CD4+/CD8+、IL-1、IL-2、IL-6等指标.结果:治疗3个月后治疗组CD3+、CD4+、CD4+,CD8+及IL-2均显著升高,CD8+、IL-6显著降低(P<0.01),与对照组比较有显著差异(P<0.05或P<0.01).结论:健脾益肾方应用于尿毒症维持血透患者,有提高细胞免疫功能的作用.     

68例老年肺结核X线胸片分析

<正> 目前,随着我国人口老龄化及结核病控制项目的实施,老龄肺结核的患病率也随之增加。为提高对老年肺结核X线胸片的高度认识,为此将我站1995年至2002年60岁以上,共68例老年肺结核病人的X线胸片认真复习,分析如下。1 临床资料1.1 诊断依据 痰结核菌阳性,抗结核治疗后X线胸片病变有吸收好转,TB-DNA(PCR)及TB-Ab阳性。1.2 病历资料 从病案中所检出病历共68例,其中男性52例(76.5％),女性16例(23.5％),年龄60～85岁,其中60～65岁35例(51.5％),66～70岁22例(32.3％),71～75岁6