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101.
心导纳微分环,肺导纳微分环最大向量正常值及其临床意义 总被引:2,自引:0,他引:2
本文报道3-50岁214例心导纳微分环(CADL)和肺导纳微分环(PADL)最大向量振幅及方位正常值,结果随增龄变化振幅递减,方位递增,多数男>女,部分组间有差异。48例左向右分流先心病环体最大向量与肺动脉压之间呈平行关系,并探讨其临床意义。 相似文献
102.
Forty cases of severe pancreatitis confirmed and treated by surgery were studied. In order to have a retrospective observation, we compared the clinical and laboratory data of 28 severe cases with that of 72 mild cases treated conservatively and found that in some cases neither Ranson nor Bank criteria were reliable in predicting the severity. We also found that frank peritonitis and bloody ascites with elevated amylase level were very good indication of pancreatic necrosis and hemorrhage. It was the author's opinion to explore early within 48 hrs after onset, using both drainage and open lesser sac lavage in most severe cases of pancreatitis. 相似文献
103.
Jian-ya Zhou Fa-di Tang Guo-gen Mao Jie Shao Yan Wang Ru-lian Bian 《浙江大学学报(医学版)》2003,32(4):315-8, 326
OBJECTIVE: To study the effect of eucalyptus globulus oil on the activity of nuclear factor-kappaB(NF-kappaB) in THP-1 cell line. METHODS: THP-1 cells were cultured with or without eucalyptus globulus oil at different concentrations (1, 10, 100 mg x L(-1), 30 min) before being stimulated with lipopolysaccharide (LPS, 1 mg x L(-1), 30 min). The location of NF-kappaB p65 subunit (NF-kappaB/p65) in THP-1 cells was detected by indirect immunofluorescence and laser scanning confocal microscope. The expression of NF-kappaB/p65 in nuclei was measured by Western-blot analysis. RESULT: The FITC-label NF-kappaB/p65 was mainly located in the nuclei after THP-1 cells were stimulated with LPS. Whereas, no fluorescence were seen in the nuclei of cells pretreated with eucalyptus globulus oil. This effect on NF-kappaB/p65 nuclear translocation was in a concentration dependent manner. CONCLUSION: Eucalyptus globulus oil inhibits the nuclear translocation of NF-kappaB induced by LPS in THP-1 cells. 相似文献
104.
中药药性量化方法对补虚药功效归类预测的研究 总被引:6,自引:0,他引:6
目的对中药药性依其重要性进行更深层次的多值量化分析,将比定性的文字表述和简单的二值量化表示更有意义.方法以补虚药为研究对象,药性为基本特征,在对其进行二值量化和多值量化的基础上,采用应用人工神经网络和决策树等数据库知识发现技术,进行对补虚药功效归类判别结果的影响研究.结论结果表明药性的不同量化方法对补虚药的功效归类预测有一定影响,多值量化比二值量化具有更为理想的判别结果. 相似文献
105.
Variants of B cell lymphoma 6 (BCL6) and marked atopy 总被引:3,自引:0,他引:3
Chaker N Adra PS Gao XQ Mao Beverly W Baron S. Pauker T. Miki T. Shirakawa JM Hopkin 《Clinical genetics》1998,54(4):362-364
106.
胸腺切除后血清乙酰胆碱受体抗体改变及与疗效关系 总被引:2,自引:0,他引:2
随访23例因重症肌无力行胸腺切除术的病人。运用灵敏度高、特异性强的BAS—ELISA法检测手术前、后血清乙酰胆碱受体抗体(AchR抗体)水平,所得结果均进行统计学分析。23例病人胸腺切除后,18例临床症状改善,有效率78%。术后14例(61%)病人血清AchR抗体水平下降,统计结果表明,手术前后血清AchR抗体水平差异有显著性(P<0.05),但与症状改善无关(P>0.05)。手术前后血清AchR抗体水平不影响疗效(P>0.05)。 相似文献
107.
急性心肌梗塞患者血清唾液酸含量测定 总被引:2,自引:0,他引:2
本文测定了50例正常人,32例急性心肌梗塞,54例冠心病无梗塞者血清SA水平,结果表明,急性心肌梗塞组血清SA水平与冠心病无梗塞组及正常人相比,具显著性差异,可能与心肌梗塞造成心肌细胞受损所致使细胞表面成份释放入血有关,所以血清SA测定可提供一新的心肌梗塞诊断依据。 相似文献
108.
Oxidant-scavenging activities of ampicillin and sulbactam and their effects on neutrophil functions. 总被引:1,自引:1,他引:0 下载免费PDF全文
Luminol-enhanced luminescence is a method used to measure formation of reactive oxygen intermediates important in the ability of neutrophils to kill microbes. Several studies have demonstrated that under some conditions of incubation, ampicillin can inhibit neutrophil-derived luminol-enhanced luminescence. We evaluated the mechanism(s) by which ampicillin inhibited the luminescent response of stimulated neutrophils. We also investigated sulbactam, a beta-lactamase inhibitor which has been given in combination with ampicillin and other beta-lactam antibiotics to increase their spectra, for possible similar effects. Both ampicillin and sulbactam attenuated luminol-enhanced luminescence by approximately 40%. Superoxide production was not prevented by added ampicillin, nor was superoxide scavenged by it. Myeloperoxidase reacts with H2O2 and Cl- to generate OCl-, which is believed to be the oxidizer of luminol that is primarily responsible for enhancement of neutrophil-derived luminescence. Hydroxyl radicals (HO.), which may also oxidize luminol, resulting in luminescence, can be formed from O2- and H2O2 via either myeloperoxidase-dependent (involving intermediate OCl-) or myeloperoxidase-independent (through a metal ion catalyst) reactions. Ampicillin scavenged H2O2 and OCl- and prevented 95% of Fenton reaction-generated HO. from reacting with 5,5-dimethyl-1-pyrroline-N-oxide. Sulbactam was found to scavenge OCl- and HO., but less avidly than ampicillin did. Neither ampicillin nor sulbactam inhibited myeloperoxidase activity. Sublethal concentrations of sulbactam had no significant effect on neutrophil killing of Staphylococcus aureus and Escherichia coli. Our results demonstrate a mechanism(s) by which ampicillin inhibits luminol-enhanced luminescence from stimulated neutrophils, namely, through scavenging of the oxidant(s) primarily responsible for the generation of luminescence. 相似文献
109.
Inapparent infection of hepatitis A virus 总被引:2,自引:0,他引:2
N Y Yang P H Yu Z X Mao N L Chen S A Chai J S Mao 《American journal of epidemiology》1988,127(3):599-604
To detect inapparent infection with hepatitis A virus, serial sera were collected from patients with hepatitis A and their contacts in two waterborne epidemics in China. Epidemic 1 occurred in a rural village near Hangzhou during August 1978-January 1979, and epidemic 2 took place in a rural primary school in Pinghu County in Zhejiang in April-May 1985. These sera were tested for antibodies against hepatitis A virus (anti-HAV), serum glutamic pyruvic transaminase (SGPT) activity, and icteric index. Feces also were collected in epidemic 1 to test for hepatitis A virus antigen. Both anti-HAV immunoglobulin M (IgM) and total anti-HAV were assayed in sera from "healthy persons" (symptomless persons without icterus and with normal SGPT level) who were in close contact with hepatitis A patients. In epidemic 1, among 18 "healthy persons", 12 were anti-HAV IgM positive, two were immune, and four susceptibles escaped infection. In epidemic 2, among 32 "healthy children", three were anti-HAV IgM positive, five had been infected by hepatitis A virus in the past, and 24 were not infected. These results demonstrate that inapparent infections occur along with overt and subclinical infections during epidemics of hepatitis A. The proportions of inapparent, subclinical, and overt infections were, respectively, 34.3%, 45.7%, and 20% in epidemic 1, and 25%, 50%, and 25% in epidemic 2. In addition, hepatitis A virus particles were demonstrated in the feces of all infected subjects who were examined and who included all levels of clinical response. These particles were identified with immuno-electron microscopy and enzyme-linked immunoassay. 相似文献
110.
宫颈粘液过氧化物酶在月经周期中的变化规律 总被引:3,自引:1,他引:2
本文对29例月经周期正常妇女的宫颈粘液过氧化物酶进行了30个周期的研究。在月经周期不同时间测定宫颈粘液过氧化物酶(CMPx)活性及血清促黄体生成素(LH)、雌二醇(E_2)和孕酮(P)。结果表明:在排卵前三天酶活性明显下降,至排卵后一天开始上升。卵泡期,酶活性与E_2呈负相关(r=-0.67);黄体期,酶活性与P呈正相关(r=0.79)。本研究提示:1.CMPx在排卵周期具有特定的变化规律,其变化受体内激素水平影响,可作为预告排卵的指标。2.如简化测定方法,可为自然避孕提供新途径。 相似文献