分叉交锁髓内钉治疗肱骨干骨折42例临床分析

①目的临床分析分叉交锁髓内钉固定治疗肱骨干骨折,并观察其治疗效果。②方法对40例肱骨干骨折及2例肱骨骨不连的患者行肱骨分叉交锁髓内钉固定术治疗,骨折病例采用闭合复位髓内钉固定,骨不连病例采用切开复位髓内钉固定加自体植骨。30例采用顺行钉固定,12例采用逆行钉固定。③结果术后随访4～20个月,40例骨折20周内骨性愈合,2例骨愈合延迟,1例一过性桡神经损伤。④结论选用合适内置物,提高手术操作技巧,使肱骨干骨折内固定治疗并发症发生率低,骨折愈合好,功能恢复佳。     

交锁髓内钉治疗肱骨干骨折的效果观察

目的:观察交锁髓内钉治疗肱骨干骨折的临床效果。方法:对46例肱骨干骨折患者行切开复位交锁髓内钉内固定治疗。结果:术后随访8~12个月,46例均骨折愈合,肩肘关节功能评价优良率为93.5%,术后无继发性桡神经损伤,无切口感染及骨不连。结论:交锁髓内钉治疗肱骨干骨折具有创伤小、固定牢固、术后并发症少,骨折易愈合等优点,可作为治疗肱骨干骨折的首选方法。     

远端分叉式交锁髓内钉治疗肱骨干骨折

目的:总结应用远端分叉式交锁髓内钉治疗肱骨干骨折的临床效果。方法:运用远端分叉式交锁髓内钉治疗肱骨干骨折17例。结果:平均手术时间65 min。切口一期愈合,无合并桡神经损伤,肩关节功能恢复满意,骨折于术后3个月愈合。结论:远端分叉式交锁髓内钉固定肱骨干骨折是一种并发症少,固定可靠,骨折愈合率高,功能恢复良好的手术方法。     

锁定钢板和交锁髓内钉治疗肱骨干骨折临床对照研究

目的比较切开复位锁定钢板内固定与闭合复位逆行交锁髓内钉内固定治疗肱骨干骨折的效果。方法 42例肱骨干骨折患者,采用随机数字表分为两组,锁定钢板组22例,采用锁定钢板内固定治疗;髓内钉组20例,采用逆行髓内钉内固定治疗,比较两组手术时间、术中出血量、住院时间、临床疗效及术后并发症。结果两组患者术后随访12~36个月,平均15个月。髓内钉组手术时间、术中出血量明显少于锁定钢板组(P<0.05),两组住院时间差异无统计学意义(P>0.05)。髓内钉组骨延迟愈合率为35.0%(7/20),明显高于锁定钢板组的9.1%(2/22)(P<0.05)。术后锁定钢板组肩关节功能优17例,良2例,差3例,髓内钉组优16例,良1例,差3例,两组肩关节功能疗效比较,差异无统计学意义(P>0.05)。结论锁定钢板及交锁髓内钉固定均为治疗肱骨干骨折有效的手术方法,交锁髓内钉固定的手术时间短,术中出血量少,但骨延迟愈合率较高。     

逆行股骨髓内钉治疗股骨远端骨折22例疗效分析

目的总结逆行交锁髓内钉内固定治疗股骨远端骨折的临床效果。方法采用逆行交锁髓内钉内固定治疗22例股骨远端骨折,术后早期进行伤肢CPM锻炼。结果22例随访6~24个月,平均15个月,骨折平均愈合时间6月,膝关节功能恢复良好,优良率86.36%。结论逆行交锁髓内钉内固定治疗股骨远端骨折具有稳定性高、固定牢靠、操作简单安全的特点;术后早期可进行伤肢CPM锻炼,骨折愈合快,并发症少,是一种治疗股骨远端骨折比较理想的方法。     

交锁髓内钉逆行置入治疗肱骨干骨折

对10例肱骨干骨折采用闭合复位，逆行置入交锁髓内钉内固定。随访5～18个月，结果10例骨折均愈合，无远期桡神经损伤及骨不连；肩肘关节功能优8例，良2例，差0例。认为逆行置入交锁髓内钉治疗肱骨干骨折具有满意的疗效。     

逆行交锁髓内钉治疗股骨髁骨折

目的:总结应用逆行交锁髓内钉治疗股骨髁骨折的方法、优点及疗效。方法:应用逆行交锁髓内钉治疗股骨髁骨折37例。结果:37例患者经3~36个月(平均13个月),随访术后骨折愈合及膝关节功能恢复均良好。结论:逆行交锁髓内钉治疗股骨髁骨折具有操作简便,固定可靠,功能恢复快,并发症少等优点,是一种比较理想的内固定方法。     

Russell-Taylor交锁髓内钉治疗肱骨干骨折

目的 :评价Russell Taylor扩髓型交锁髓内钉治疗肱骨干骨折的临床效果。方法 :对 2 6例肱骨干骨折患者采用Russell Taylor扩髓型交锁髓内钉治疗 ,其中 19例采用顺行髓内钉 ,7例采用逆行髓内钉。结果 :平均随访16个月 ( 6～ 2 4个月 ) ,全部获骨性愈合 ,平均愈合时间 4.7个月 ( 3～ 8个月 ) ,肩关节功能优 18例 ,良 5例 ,一般 3例。肘关节功能优 2 3例 ,良 3例 ,1例病人出现近端交锁螺钉的肩关节撞击症状。无感染及医源性骨折和周围神经损伤等并发症。结论 :Russell Taylor扩髓型交锁髓内钉是治疗肱骨干骨折的有效方法。     

逆行髓内钉治疗肱骨干骨折的体会

目的探索利用逆行交锁髓内钉治疗肱骨干骨折的疗效。方法对38例肱骨干骨折患者均使用逆行肱骨交锁髓内钉内固定,其中,11例行闭合复位,有27例行切开复位。结果38例患者中有35例完全愈合,愈合时间为8周-13周,平均愈合时间为10周。在38例患者中无1例发生患肢的肩关节、肘关节的功能障碍。结论逆行交锁髓内钉在治疗肱骨干骨折中是一种较为理想的内固定方法。     

交锁髓内钉治疗肱骨干骨折的疗效

目的评价采用交锁髓内钉治疗肱骨干骨折的临床效果。方法对24例肱骨干骨折采用闭合复位或有限切开复位交锁髓内钉固定并随访11~17个月。结果 24例中23例骨折愈合,有1例骨折延迟愈合经取除远端锁钉动力化后骨折愈合,平均愈合时间为15周。肩关节功能按Neer评分,优12例,良10例,可2例,优良率为91.6%。结论肱骨交锁髓内钉对骨折端的血运影响较小、固定牢靠,是治疗肱骨干骨折的有效方法。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…