不同运动项目对大学生抑郁症状干预效果的研究

目的 研究不同体育运动项目对大学生轻度或中度抑郁症状的干预效果.方法 采用抑郁自评量表(self-rating depression scale,SDS)筛选抑郁得分在轻度和中度水平(41 ～ 55分)的大学生共120名,分为体育舞蹈练习组、篮球练习组和乒乓球练习组,各组均在专业教师的指导下进行为期16周练习,运用抑郁自评量表跟踪被试者每4周后的抑郁变化情况.结果 干预后各组的抑郁得分显著低于干预前(P＜0.01);运动显著改善了被试者的躯体化和抑郁因子2类症状(P＜0.01);其中体育舞蹈组的效应量和效应速度均优于其它运动组(P＜0.01).结论 不同的体育运动均可有效降低大学生的抑郁水平;体育舞蹈练习是干预大学生心理健康水平的最佳运动.     

医护人员综合性心理干预的效果及对患者满意度的影响研究

目的 通过对医护人员进行综合性心理干预,评估干预的效果,以及患者对医护人员满意度的影响.方法 取某综合医院一线临床科室医护人员327例,从SDS、SAS量表得分超过正常值的人群中按得分较高的选取50人,随机分入干预组和对照组,每组25人.采用综合性心理干预,包括团体心理治疗,催眠放松治疗,个体心理治疗等方法对干预对象实施为期12周的心理干预,使用抑郁自评量表(self rating depression scale,SDS)、焦虑自评量表(self-rating anxiety scale,SAS)及自编患者满意度量表进行问卷调查.结果 干预组医护人员干预前后SAS/SDS得分比较,差异有统计学意义(P<0.05);对照组医护人员干预前后SAS/SDS得分进行比较,差异无统计学意义(P>0.05);试验组经过干预后,患者对其满意度明显提高,差异有统计学意义(P<0.05);对照组干预前后患者满意度得分进行比较,差异无统计学意义(P>0.05).结论 综合性心理干预提高了医护人员的心理健康水平,同时提高了患者对其满意度.     

玫瑰解郁汤联合穴位埋线及耳穴贴压治疗血液透析患者抑郁症临床研究

目的:观察玫瑰解郁汤联合穴位埋线及耳穴贴压疗法治疗血液透析患者抑郁症的临床疗效。方法:选取患有抑郁症的血液透析患者66例,随机分为观察组和对照组,每组各33例。观察组采用玫瑰解郁汤联合穴位埋线、耳穴贴压治疗,对照组单纯采用玫瑰解郁汤治疗。观察治疗后两组患者汉密尔顿抑郁量表(Hamilton depression scale,HAMD)评分及抑郁自评量表(self-rating depression scale,SDS)评分,评价临床疗效。结果:治疗后两组患者HAMD评分及SDS评分均较治疗前降低,观察组优于对照组,两组比较,差异有统计学意义(P0.05);观察组有效率84.9%,对照组有效率57.6%,两组比较,差异有统计学意义(P0.05);两组治疗期间均未出现明显不良反应。结论:玫瑰解郁汤联合穴位埋线、耳穴贴压疗法治疗血液透析患者抑郁症效果明显,无明显不良反应。     

绘画干预联合认知行为护理对青少年抑郁症患者抑郁症状及日常生活能力的影响

目的 研究绘画干预联合认知行为护理对青少年抑郁症患者抑郁症状及日常生活能力的影响。方法 以九江市第五人民医院2020年1月—2021年6月收治的60例12～18岁抑郁症患者为研究对象,按随机数表法分为观察组（27例）和对照组（33例）,对照组实施常规干预护理,观察组实施绘画干预联合认知行为护理,2组均干预8周。观察并比较干预前、干预8周后2组患者的心理状态、生活能力、生活质量、护理满意度。结果 干预8周后2组患者的焦虑自评量表（self-rating anxiety scale,SAS）、抑郁自评量表（self-rating depression scale,SDS）、症状自评量表（symptom checklist 90,SCL-90）、日常生活活动能力量表（activities of daily living,ADL）得分均较干预前下降,差异有统计学意义（P<0.05）;干预8周后观察组SAS、SDS、SCL-90、ADL得分低于对照组,差异有统计学意义（P<0.05）;干预8周后2组患者的护士用住院病人观察量表（nurses observation scale for...     

126例高血压患者焦虑抑郁情绪的调查分析

目的 分析原发性高血压患者焦虑抑郁情绪的伴发情况.方法 采用Zung编制的焦虑自评量表(self-rating anxiety scale,SAS)和抑郁自评量表(self-rating depression scale,SDS),对原发性高血压患者126例和体检健康者120例进行评定分析.结果 高血压组焦虑发生率35.7%,抑郁发生率15.9%;对照组焦虑发生率25.8%,抑郁发生率6.6%.高血压组SAS、SDS得分明显高于对照组,差异有统计学意义(P<0.05).结论 部分原发性高血压患者存在明显焦虑抑郁情绪,应加强临床医生对焦虑抑郁症状的识别.     

创伤后应激障碍的心理干预体会

目的:在对创伤应激障碍(Posttraumatic stress disorder,PTSD)者心理干预、焦虑、抑郁明显改善。方法:咨询前后分别用焦虑自评量表(Self-rating anxiety scale,SAS)、抑郁自评量表(Self-rating depression scale,SDS)评分,以示心理咨询效果。结论:来访者受创后越早心理咨询及干预,症状改善明显,效果越好。继发躯体疾病后干预时间长、效果欠佳。     

正念认知疗法对新冠肺炎(COVID-19)疫情中线上求助者焦虑抑郁情绪的影响

[目的]探讨短程正念认知疗法对新冠肺炎(coronavirus disease 2019,COVID-19)疫情中线上求助者焦虑抑郁情绪的影响。[方法]选取COVID-19疫情中打进热线电话咨询且伴有焦虑抑郁情绪的99例求助者为研究对象,进行4周8次线上短程正念认知治疗。使用焦虑自评量表(selfrating anxiety scale,SAS)、抑郁自评量表(self-rating depression scale,SDS)、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)和汉密尔顿抑郁量表(Hamilton depression scale,HAMD)(17项)评估求助者治疗前后焦虑抑郁水平的改善程度,并对比不同程度焦虑抑郁求助者之间的治疗效果差异。用五因素正念度量表(five facet mindfulness questionaire,FFMQ)对治疗前后正念水平进行评价。[结果]4周8次的短程正念认知治疗后,求助者SAS表评分(43.47±5.67)分,SDS表评分(42.05±5.45)分,HAMA表评分(9.04±2.68)分,HAMD(17项)表评分(8.06±2.70)分,均明显低于治疗前,差异有统计学意义(P0.01);焦虑抑郁程度越高者,经短程正念认知治疗后,改善越明显,差异有统计学意义(P0.01)。治疗后FFMQ得分(111.75±7.23)分,明显高于治疗前,差异有统计学意义(P0.01)。[结论]运用4周8次短程正念认知干预技术,可以有效降低COVID-19疫情中线上求助者的焦虑、抑郁水平。     

护理干预在肺癌合并尘肺患者三维适形放疗作用中的应用

目的探讨护理干预对肺癌合并尘肺患者焦虑及抑郁的影响。方法将19例肺癌合并尘肺患者在常规三维适形放疗(three dimensional conformal radiation therapy,即:3D-CRT)的基础上加用护理干预技术,患者在治疗前、治疗结束时采用抑郁自评量表(self-rating anxiety scale,即:SAS)、焦虑自评量表(self-rating depression scale,即:SDS)进行问卷调查。结果全部患者治疗结束后SAS及SDS得分均明显降低,较治疗前差异有统计学意义(P<0.05)。结论肺癌合并尘肺患者存在明显的心理障碍,护理干预可显著减低患者的焦虑、抑郁程度。     

脑卒中患者抑郁状态的临床特征与预后

为探讨脑卒中患者的抑郁特点,作者应用汉密顿抑郁量表（Hamilton depression scale,HAMD）、Zung氏抑郁自评量表（self-rating depression scale,SDS）、Zung氏焦虑自评量表（self-rating anxiety scale,SAS）,对110例脑卒中患者进行评定,并与18例抑郁症患者比较。1资料与方法1.1对象研究病例为2002/2007年在我院住院病人,符合《中国精神障碍分类与诊断标准第3版（CCMD-3）》中抑郁症的诊断标准,年龄在40岁以上,其中男86例,女性24例,平均年龄（59.9±14.3）岁,病程≥2周,有神经系统体征的脑卒中患者入组。排除标准：意识障碍;精神障碍既往史或家族史阳性者;简明智能状态检查表（mini-mental status examination,MMSE）总分小于17,有明显的痴呆症状;严重的心、肝、肾功能损害;神经系统退行性疾病。18例抑郁症患者为同期在我院门诊就诊者,排除器质性抑郁和反应性抑郁。     

产后抑郁干预中助产士主导模式对产妇SDS评分的影响

目的 探讨助产士主导的护理模式在产后抑郁产妇中的效果。方法 选取2021年1月至2022年1月诸暨市人民医院收治的产后抑郁患者400例，采用随机数字表法将其分为观察组（n=200）和对照组（n=200）。两组患者均接受相同的治疗，对照组接受常规心理护理，观察组接受助产士主导的护理模式。比较两组患者护理前及护理4周后爱丁堡产后抑郁量表（Edinburgh postnatal depression scale，EPDS）得分、汉密尔顿抑郁量表（Hamilton depression scale，HAMD）得分、抑郁自评量表（self-rating depression sale，SDS）得分及世界卫生组织生活质量测定简表（World Health Organization quality of life -brief，WHOQOL-BREF）得分，以及护理4周后的疗效。结果 护理前，两组EPDS、HAMD-17及SDS得分比较，差异均无统计学意义（P>0.05）；护理4周后，两组EPDS、HAMD-17及SDS得分均低于护理前，且观察组的EPDS、HAMD-17及SDS得分均低于对照组，差异均有统计学意义（P<0.05）。护理前，两组的WHOQOL-BREF总分以及各维度得分比较，差异均无统计学意义（P>0.05）；护理4周后，两组WHOQOL-BREF总分及各维度得分均高于护理前，且观察组的WHOQOL-BREF总分及各维度得分均高于对照组，差异均有统计学意义（P<0.05）。观察组的治疗总有效率高于对照组，差异有统计学意义（P<0.05）。结论 助产士主导的护理模式可以有效降低产妇产后抑郁的发生率，提高产后的生活质量，对促进产妇心理健康方面具有积极的意义。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…