脑电生物反馈治疗儿童抽动障碍的疗效分析

目的:研究脑电生物反馈治疗对儿童抽动症的临床疗效。方法:采用脑电生物反馈技术对17例抽动症患儿进行治疗。结果:17例抽动症患儿的运动性抽动、发声性抽动评分及抽动总评分均较治疗前有显著降低,均有统计学意义(P(0.05)。结论:脑电生物反馈治疗儿童抽动症具有良好的疗效,是治疗儿童抽动症的一种新方法。     

脑电生物反馈治疗儿童抽动障碍疗效分析

目的探讨脑电生物反馈治疗儿童抽动障碍的疗效。方法对2006年9月-2008年8月儿科门诊的抽动障碍患儿进行平均为30次的脑电生物反馈治疗,治疗前后分别采用多发性抽动症综合量表（TSGS）进行疗效评定。结果32例患儿经生物反馈治疗,显效8例,好转21例,无效3例,有效率达90.6%。结论脑电生物反馈是治疗儿童抽动障碍一种安全有效的治疗方法。     

认知行为干预联合脑电生物反馈治疗抽动障碍患儿问题行为的影响

目的探讨认知行为干预联合脑电生物反馈治疗抽动障碍患儿问题行为的影响。方法选择该院在2014年9月‐2017年8月收治的100例抽动障碍患儿进行研究。采用随机数字表法将患儿分为两组,每组各50例。两组均根据临床表现给予常规药物治疗,对照组加以认知行为干预,观察组在此基础上联合脑电生物反馈治疗。以疗效评价、耶鲁综合抽动严重程度量表(YGTSS)评分及问题行为作为评价指标。结果疗效判定结果显示观察组总有效率明显高于对照组(92.00%vs. 76.00%)(P 0.05)。治疗后两组患儿运动性抽动评分、发声性抽动评分及Coners父母问卷得分均明显下降(P 0.05),且观察组下降更为明显(P 0.05)。结论认知行为干预联合脑电生物反馈治疗较单独进行认知行为干预可明显提高抽动障碍患儿的治疗效果,降低YGTSS评分、改善问题行为。     

脑电反馈对共患注意缺陷多动障碍和学习障碍儿童血清β-内啡肽、脑源性神经营养因子影响

目的 探讨脑电生物反馈治疗对共患注意缺陷多动障碍(ADHD)和学习障碍患儿血清beta-内啡肽(β-EP)、脑源性神经营养因子(BDNF)影响.方法 应用Sprit-8脑电生物反馈治疗仪,对48例(6～12岁)共患ADHD和学习障碍儿童进行40次增强16～20 Hz β波,抑制4～8 Hz θ波脑电反馈治疗,采用脑电反馈仪检测患儿脑电波θ/β、θ/SMR功率比值的变化,采用酶联夹心免疫吸附测定法检测血清浓度.结果 脑电反馈治疗后患儿θ/β、θ/SMR值较前明显下降(P<0.01),血清β-EP浓度[(191.01±22.85)pg/ml]较前[(180.29 4-32.38)pg/ml]升高(t=3.86,P<0.01),血清BDNF浓度前后分别为(6.12±6.44)ng/ml,(4.40±3.68)ng/ml,差异无显著性(t=1.71,P>0.05).结论 β-EP可能在脑电生物反馈治疗共患ADHD和学习障碍机制中扮演蕈要角色.     

可乐定控释贴剂联合安舒汤治疗抽动障碍临床观察

<正>抽动障碍(tic disorders,TD)起病于儿童期,是以抽动为主要临床表现的神经精神疾病[1]。主要表现为不自主、反复、快速而又无目的的一个或多个部位肌肉运动性或发声性的抽动。根据临床症状、病情的轻重及病程的长短,抽动障碍分为短暂性抽动障碍、慢性抽动障碍、多发性抽动症(Tourette综合征)3种类型[2]。1临床资料2014年12月—2015年11月我院儿童神经专     

脑电生物反馈治疗儿童抽动障碍疗效研究

目的 探索脑电（EEG）生物反馈治疗儿童抽动症的疗效。方法 将100例抽动障碍患儿随机分组：对照组50例采用药物治疗。治疗组50例采用EEG生物反馈治疗。比较两组的治疗效果、副反应及反复性。结果 在疗效、疗程、副反应方面。治疗组均优于对照组。结论 脑电生物反馈治疗儿童抽动障碍优于药物治疗，既无创伤,又无副作用，疗效显著。     

心理行为干预联合药物治疗对儿童抽动症的改善作用

目的 探讨心理行为干预联合药物治疗对儿童抽动症的改善作用.方法 选取抽动症患儿87例,随机分为干预组(46例)和对照组(41例),对照组患儿给予盐酸硫必利口服治疗,干预组患儿在对照组治疗的基础上给予心理行为干预,采用耶鲁综合抽动严重程度量表(YGTSS)评估2组患儿治疗前后运动、发声抽动情况.结果 干预组和对照组患者治疗总有效率分别为91.30%、75.61%,组间比较差异具有统计学意义(P<0.05).2组患者治疗前运动抽动YGTSS评分:干预组(15.48±2.27)分,对照组(15.36±2.10)分;治疗前发声抽动YGTSS评分:干预组(9.62±3.67)分,对照组(9.58±3.72)分,差异均无统计学意义.2组患者治疗后运动抽动YGTSS评分:干预组(2.81±2.05)分,对照组(6.73±2.44)分;治疗后发声抽动YGTSS评分:干预组(2.17±1.83)分,对照组(4.62±1.88)分,干预组患者运动和发声抽动YGTSS评分均明显低于对照组患者(P<0.05).结论 心理行为干预可显著提高抽动症患儿口服盐酸硫必利治疗的效果.     

脑电生物反馈治疗注意缺陷多动障碍患儿疗效分析

目的观察脑电生物反馈治疗儿童注意缺陷多动障碍(ADHD)的效果,为临床治疗ADHD提供参考依据。方法 ADHD患儿153例,脑电生物反馈治疗40次,采用视听整合持续操作测验(IVA-CPT)评定治疗效果。结果经过脑电生物反馈治疗后,ADHD患儿脑电波β波和SMR.波频率较治疗前提高,θ波频率较治疗前降低,差异有统计学意义(P<0.05)。听觉反应控制商数、视觉反应控制商数、听觉注意力商数、视觉注意力商数、听觉警醒商数、视觉觉醒商数较治疗前均提高,差异有统计学意义(P<0.05)。结论单纯脑电生物反馈治疗ADHD效果显著。     

脑电生物反馈治疗儿童抽动症临床疗效分析

目的探讨采用BFB2000脑电生物反馈治疗儿童抽动症的临床疗效,为儿童抽动症寻求更好的治疗方法。方法对2004年8月至2006年8月38例儿童抽动症采用生物反馈治疗平均20次。结果31例临床症状缓解,4例疗效不佳。结论脑电生物反馈治疗儿童抽动症不失为一种安全有效的治疗办法。     

利培酮联合脑电生物反馈对精神分裂症患者认知功能、日常行为能力及睡眠脑电活动的影响观察

目的:观察利培酮联合脑电生物反馈治疗精神分裂症的临床疗效,以及对患者认知功能、日常行为能力及睡眠脑电活动的影响。方法:选择本院收治的80例精神分裂症患者为研究对象,按治疗方式不同分为对照组和研究组,每组各40例。对照组予以利培酮治疗,研究组予以利培酮联合脑电生物反馈法治疗。记录两组患者治疗前、治疗6周后临床症状评定[简明精神病量表(BPRS)]、日常行为能力和社会能力[日常生活能力量表(ADL)、社会功能评定量表(SSPI)]、认知功能[简单视觉空间记忆测验(BVMT-R)]及睡眠脑电活动[多导睡眠监测(PSG)]。结果:治疗6周后,两组患者BPRS、ADL、睡眠N1期水平均低于治疗前,且研究组低于对照组(P<0.05);两组患者SSPI、BVMT-R、TST、SE、睡眠N3期水平高于治疗前,除BVMT-R(2)、SE外,研究组均高于对照组(P<0.05)。结论:利培酮联合脑电生物反馈治疗可以帮助精神分裂症患者改善症状,调节患者睡眠质量,有一定临床推广应用价值。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…