子午流注针法治疗黄褐斑的疗效观察

目的观察子午流注针法治疗黄褐斑的疗效。方法将80例黄褐斑就诊者按1：1比例随机分成治疗组和对照组。子午流注针法加面针治疗组，采用子午流注按时取穴针法，再加面部色斑区，合谷穴。对照组只取面部色斑区，合谷穴。结果治疗组的疗程日月显短于对照组（P〈0．05），两组疗效比较无显著差异。结论子午流注针法加面针治疗黄褐斑能明显缩短疗程。     

子午流注纳甲法治疗慢性咽炎38例临床研究

目的观察子午流注纳甲法针刺治疗慢性咽炎的疗效。方法以观察表序号将70例患者随机分两组，观察组38例，采用子午流注纳甲法、体针疗法治疗；对照组32例。采用与观察组相同的体针疗法治疗。结果治疗1疗程后统计显示，观察组的临床治愈率、总有效率均优于对照组（P〈0．05）。结论运用子午流注纳甲法配合体针疗法治疗本病具有缩短疗程、提高疗效、复发率低等优点。     

多种穴位刺激法治疗阳虚型膝关节炎的疗效及安全性评价

目的:比较子午流注低频疗法、单纯低频疗法及传统针刺疗法治疗阳虚型膝关节炎的疗效及安全性。方法:采用随机双盲对照,将72例患者平均分为3组,运用VAS疼痛视觉量表和WOMAC量表观察比较3组治疗针对疼痛症状的疗效及安全性。结果:3组治疗7天、14天时VAS评分差异有非常显著意义(P<0.01),子午流注组明显低于其他两组;疗后与疗前差值比较,差异有非常显著意义(P<0.01),子午流注组大于其他两组;而WOMAC量表疼痛评分在治疗7天时无显著差异(P>0.01),但在第14天时差异有显著意义(P<0.01),子午流注组明显优于其他两组。结论:子午流注低频疗法较其他两种方式更能有效缓解阳虚型膝关节炎患者的疼痛症状且安全易于耐受。     

子午流注针法治疗痛经疗效观察

目的通过观察子午流注针法治疗痛经的临床疗效,评价该方法对痛经患者的影响,从而为临床治疗此病提供一疗效确切的治疗方法。方法依据循证医学/DME原则,运用随机盲法,将106例痛经患者随机分为两组,以53例应用子午流注因时取穴针法治疗痛经为观察组,以另53例应用普通常规辨证论治针法治疗痛经为对照组。对子午流注因时取穴针法治疗痛经的有效性进行临床观察和评价。结果两组临床疗效比较差异有统计学意义(P0.05);两组治疗前后VAS评分比较差异有统计学意义(P0.05);两组治疗后VAS评分比较差异亦有统计学意义(P0.05)。结论运用子午流注因时取穴针法治疗痛经临床疗效明显优于单纯使用普通针法。     

子午流注纳子针法对哮喘患者PEF及IL-4的影响

目的观察子午流注纳子针法对哮喘患者呼气峰流量(PEF)及血清白介素-4(IL-4)的影响。方法将60例哮喘患者随机分为子午流注纳子针法组(观察组)和常规针法组(对照组),每组30例,治疗4个疗程。观察针刺前后PEF、IL-4的水平,并进行比较。结果两组针法对PEF的改善均有统计学意义(P<0.05),但观察组改善优于对照组;两组针法均能降低哮喘患者血清中IL-4的水平,此效应以前者尤为明显(P<0.01)。结论子午流注纳子针法能更好地改善哮喘患者的呼气峰流量及白介素-4的水平。     

Effect of polypeptide 2B1 on condition of dampness pattern in rats in terms of Traditional Chinese Medicine

Objective

This study investigated how polypeptide 2B1 is involved in regulating and governing dampness in rat models with dampness pattern defined in terms of Traditional Chinese Medicine.

Methods

We randomly divided 48 SPF 10-week-old male Sprague-Dawley (SD) rats into a normal group, normal + Aristolochic acid I (AA-I) for 5 min group, normal + AA-I for 60 min group, dampness pattern group (DS-Group), dampness pattern + AA-I for 5 min group, and dampness pattern + AA-I for 60 min group. Groups were then treated accordingly. We took out the lung, stomach, liver, spleen, kidney, large intestine, and small intestine tissues to detect gene and protein expression of organic anion transporter polypeptide 2B1 (OATP2B1).

Results

Gene expression of OATP2B1 in spleen, kidney, and small intestine of rats with dampness pattern was lower than that in normal rats (P<0.05). The gene expressions of OATP2B1 in liver, stomach, large intestine, and small intestine were lower than that in control rats at different time points after being stimulated by AA-I (P<0.05).

Conclusion

There is coordination among multiple viscera in handling the condition of dampness, and the mechanism underlying the action may rely on regulating the expression of OATP2B1.     

“个体化计时”子午流注针法治疗脑卒中后肩痛临床研究

目的 :观察"个体化计时"子午流注针法治疗脑卒中后肩痛的临床疗效。方法 :90例脑卒中后肩痛患者随机分为治疗组和对照组各45例,治疗组采用"个体化计时"子午流注针法,对照组采用"地方平太阳时"子午流注针法,10 d为一疗程,治疗3个疗程后观察比较临床疗效。结果:治疗组与对照组总有效率分别为88.89%、82.22%,两组比较差异无统计学意义(P0.05);两组治愈率分别为44.44%和26.67%,治疗组优于对照组(P0.05)。结论:"个体化计时"子午流注针法治疗脑卒中后肩痛疗效显著。     

子午流注治疗周围性面瘫的临床观察

目的:观察子午流注针法治疗周围性面瘫的疗效,避免药物的毒副反应。方法:23例周围性面瘫患者随机分为针刺组和对照组,其中针刺组12例按日定时取穴,针刺与之相关的五输穴;对照组11例依照常规西医治疗。结果:针刺组和对照组比较,治疗有效率差异无统计学意义(P>0.05)。结论:纳子法定时取穴治疗周围性面瘫的疗效与西药治疗效果基本相同,但针刺取穴少,较方便,患者容易接受。     

Curative effect of warming kidney and fortifying spleen recipe on diarrhea-predominant irritable bowel syndrome

Objective

To observe the curative effect of a recipe for warming the kidney and fortifying the spleen on diarrhea-predominant irritable bowel syndrome (IBS-D).

Methods

This multi-center, double-blind, randomized, and controlled trial included 240 patients that met the inclusion criterion and were then divided into two groups of 120. Patients in the treatment group (group A) took modified Sishen Wan orally for warming the kidney and fortifying the spleen and patients in the control group (group B) took a placebo, Chao Maiya, for 4 weeks. 28 days after withdrawal, there was a 6-month follow-up to observe patient recurrence condition. The total effective rate, curative effect, and recurrence rate were evaluated after treatment.

Results

There was statistical difference (P<0.01) between the two groups in total effective rate (92.24% in the treatment group and 49.07% in the control group), in curative effect of TCM syndrome (90.52% and 47.22%, respectively), and in the recurrence rate (15.79% and 56.86%, respectively) within 6 months after treatment.

Conclusion

Modified Sishen Wan, for warming the kidney and fortifying the spleen, can effectively treat IBS-D and better control its recurrence.     

子午流注取穴治疗类风湿性关节炎临床研究

目的:探索子午流注针法治疗类风湿性关节炎的临床疗效。方法:选取类风湿性关节炎患者120例,随机分为子午流注组,辨证取穴组和联合治疗组(子午流注组+辨证取穴组),分别治疗。结果:子午流注组40例,显效11例,有效11例,进步9例,无效9例,总有效率77.5%;辨证取穴组40例,显效10例,有效11例,进步11例,无效8例,总有效率80.0%;联合治疗组40例,显效15例,有效13例,进步10例,无效2例,总有效率95.0%;联合治疗组疗效优于其他2组(P<0.01)。治疗后Lysholm膝关节量表评分结果显示联合治疗组疗效优于其他2组(P<0.01)。结论:子午流注针法治疗类风湿性关节炎具有确切临床疗效,与辨证取穴联合治疗具有增效作用。