Comparison of various capsulectomy techniques in cataract surgery. An experimental study]

Radial tears at the edge of an anterior capsulectomy are often associated with the occurrence of intraocular lens (IOL) loops coming out of the capsular bag with subsequent IOL decentration. We analyzed the incidence of radial tear formation in 40 human eyes obtained postmortem. These eyes were randomly assigned to four groups: "can opener," linear capsulotomy, capsulopuncture ("postage stamp"), and continuous curvilinear capsulorhexis (CCC). The CCC appeared to be much less likely to be associated with anterior capsular radial tears as opposed to the other three techniques. With the nucleus expression technique used in this study, radial tears occurred in all cases of "can opener," linear capsulotomy and capsulopuncture, whereas no tears occurred with the CCC technique. The results of this study show that CCC is currently the best available anterior capsulectomy procedure for minimizing the incidence of radial tears and sequelae such as decentration.     

Prevention of anterior capsule contraction by anterior capsule relaxing incisions with neodymium:yttrium-aluminum-garnet laser

PURPOSE: To examine the effect of two or three neodymium:yttrium-aluminum-garnet (Nd:YAG) laser relaxing incisions made in the anterior capsular rim on prevention of anterior capsule contraction after cataract surgery. DESIGN: Randomized clinical trials. METHODS: One hundred patients scheduled for bilateral cataract surgery were randomized to one of two groups: two or three relaxing incisions in the left eye and no incisions in the right eye, and relaxing incisions in the right eye and no incisions in the left eye. The anterior capsule opening area was measured using Scheimpflug photography immediately after capsulotomy and at one, three, and six months after capsulotomy, and the percentage reduction was calculated. The degree of intraocular lens (IOL) decentration and tilt and of posterior capsule opacification (PCO) also were examined. RESULTS: There was no significant difference in the anterior capsule opening area between fellow eyes at baseline (P > or = .1770). In patients who underwent two incisions, no significant difference was found between fellow eyes in the opening area (P > or = .4098) or in the percentage of reduction (P > or = .8730) throughout follow-up. In patients who underwent three incisions, the opening area in eyes with capsulotomy was significantly greater than that in eyes without capsulotomy (P < or = .0154), and the percentage reduction was significantly smaller in eyes with capsulotomy than in eyes without capsulotomy (P < or = .0016). No significant differences were found in the IOL decentration and tilt, or in PCO. CONCLUSIONS: Three relaxing incisions made in the anterior capsule decrease the anterior capsule contraction, whereas two incisions do not.     

Tilt and decentration of bag-fixated intraocular lenses: A comparative study between capsulorhexis and envelope techniques

Malposition of an intraocular lens (IOL) may cause symptoms such as glare, halos, and other visual aberrations. The purpose of this study is to determine the effect of two different anterior capsulotomy techniques on IOL tilt and decentration. Bag-fixated IOL implantation after uncomplicated extracapsular cataract extraction was performed using both envelope (65 eyes) and continuous circular capsulorhexis (CCC) technique (42 eyes). Eyes were followed-up at least 6 months postoperatively. While the mean IOL decentration after envelope technique was found to be 0.65 mm, this was 0.15 mm after CCC technique. On the other hand, the mean actual tilting angle of IOL after envelope technique was 5.66 degrees, whereas this was 1.13 degrees after CCC technique. The aforementioned differences were statistically significant (p<0.01, and p<0.01). Furthermore, in 17 eyes (26.1%) where envelope technique and in 29 (69.0%) eyes where CCC technique was used demonstrated no IOL tilt and decentration. This study shows that the CCC technique may result in less optical problems due to IOL malposition compared to the envelope technique.Abbreviations IOL intraocular lens - IOLs intraocular lenses - CCC continuous circular capsulorhexis - ECCE extracapsular cataract extraction Read in part before the IXth Congress of Societas Ophthalmologica Europea, Brussels, May 23–28, 1992.The authors do not have any commercial or proprietary interest in any of the companies or products mentioned in this communication     

Analysis of capsular bag defects and intraocular lens positions for consistent centration

Radial anterior capsular tears frequently occur in posterior-chamber iris-plane phacoemulsification cases. These tears extend to the capsular bag equator and can allow the knee of an in-the-bag posterior chamber intraocular lens (IOL) to unfold a smaller anterior capsular remnant. This unfolding can allow the knee of the IOL loop to extend beyond the capsular equator, leading to IOL decentration. Typical anterior capsular radial tear configurations along with guidelines for IOL design selection and orientation after recognition of these tears are presented. Proper IOL centration was achieved in 255 of 262 patients (97%) in a study observing these guidelines.     

Comparison of anterior vitrectorhexis and continuous curvilinear capsulorhexis in pediatric cataract and intraocular lens implantation surgery: a 10-year analysis.

PURPOSE: To analyze the rate of inadvertent anterior lens capsular tears with vitrectorhexis or continuous curvilinear capsulorhexis (CCC) in pediatric cataract and intraocular lens (IOL) implantation surgery between January 1, 1997, and December 31, 2006. METHODS: Retrospective chart review, collecting for each eye: age at cataract surgery, type of anterior capsulotomy, any tearing of the capsule, and if yes, details of the tear. RESULTS: A total of 737 eyes were reviewed. Cases with a ruptured lens capsule that occurred prior to surgery were excluded. Eyes that received an anterior capsulotomy by any other method (n = 27) or eyes that did not receive an IOL (n = 100) were reviewed but excluded from final comparative analysis. Of the remaining 339 eyes, 19 eyes (5.6%) were noted to develop an anterior capsule tear (vitrectorhexis, 12 of 226 eyes, 5.3%; CCC, 7 of 113, 6.2%). These tears occurred during anterior capsulotomy in seven eyes, hydrodissection in one, cataract removal in three, and IOL insertion/manipulation in eight. In eyes operated for cataract at or before 72 months of age, the manual CCC technique was more likely to develop a tear (relative risk, 3.09) compared with eyes of older children (>72 months of age), where the vitrectorhexis technique was more likely to develop a tear (relative risk, 3.14). CONCLUSIONS: Vitrectorhexis is well suited for use in children less than 6 years of age due to their highly elastic anterior lens capsule. For children aged 6 years and older, manual CCC is the best technique because, by that age, capsule control and ease of capsulotomy completion has improved.     

Prospective experimental study of factors related to posterior chamber intraocular lens decentration.

The effect of posterior chamber intraocular lens (IOL) dimensions, design, style, loop fixation, and anterior capsular tears on decentration were investigated in an experimental model. Nine posterior chamber IOLs of various designs and styles with loop diameters between 12.0 and 14.0 mm and optic diameters between 5.0 and 7.0 mm were implanted in human eyes obtained post mortem. Symmetrical and asymmetrical fixation were investigated in eyes with and without radial tears using the Miyake posterior view technique. Location of IOL loops proved to be the most significant factor in IOL decentration. Decentration was least with symmetrical bag/bag fixation and no radial tears (mean = 0.20 +/- 0.05 mm). Asymmetrical bag/sulcus fixation in the presence of anterior capsular tears was associated with the highest decentration rate (mean 0.68 +/- 0.28 mm). Optic size and total loop diameter had no apparent effect on IOL centration in the immediate postoperative period.     

Two-stage capsulorhexis for endocapsular phacoemulsification

The continuous tear anterior capsulotomy or capsulorhexis technique is important for safe, successful cataract extraction and intraocular lens (IOL) implantation surgery. A two-stage continuous tear capsulotomy or capsulorhexis extends the possibility of achieving continuous tear capsulotomy to challenging and complicated cases. In endocapsular phacoemulsification this technique preserves the integrity of the capsule because it prevents the extension of radial tears in the capsule and thus facilitates safe cataract extraction and secure in-the-bag IOL placement. The benefits and advantages of the continuous tear capsulotomy are preserved by two-stage capsulorhexis.     

不同截囊方法的比较研究

以兔眼为实验材料，以临床操作模式为方法，在标准条件下，比较４种截囊术前囊膜辐射状撕裂的发生率，４种截囊术是：开罐式截囊，邮票（点刺）式截囊，线状截囊和环形撕囊术。实验结果证实，环形囊术较其它３种截囊方法有更多优点，应用本文介绍的后压法娩出晶体核后，撕囊术组中未见发生前囊膜辐射状撕裂，其它３组则１００％发生。     

Neodymium:YAG laser anterior capsulotomy for capsular contraction syndrome.

BACKGROUND AND OBJECTIVE: This study presents the outcome of neodymium:YAG laser anterior capsulotomy for capsular contraction syndrome, the safety profile and effectiveness of which are unclear. PATIENTS AND METHODS: Records of 32 patients with a minimum of 3 months of follow-up were reviewed retrospectively. The procedure was considered successful if all of the following criteria were met: centered intraocular lens (IOL) or no obvious change in IOL centration post-capsulotomy, no evidence of re-phimosis in the follow-up period; and no further requirement for surgical intervention due to capsular contraction syndrome in the follow-up period or complications were recorded. RESULTS: The procedure was successful in 25 case; (78%). Failed cases (n = 7, 22.0%) included 5 cases of re-phimosis and 2 cases with progressive IOL decentration. The failure rate was higher in cases with preoperative IOL decentration (P< .01). CONCLUSION: Neodymium:YAG laser anterior capsulotomy was successful in the majority of cases. The failure rate was higher with preoperative IOL decentration.     

Comparison of tilt and decentration of 1-piece and 3-piece hydrophobic acrylic intraocular lenses

PURPOSE: To determine the amount of tilt and decentration of 1-piece and 3-piece hydrophobic acrylic intraocular lenses (IOLs) in patients having cataract surgery. SETTING: Department of Ophthalmology, Gulhane Military Medical Academy and Medical School, Ankara, Turkey. METHODS: Eighty-eight patients having phacoemulsification with IOL implantation were divided into 2 groups. One group received a 3-piece hydrophobic acrylic IOL with 12.5 mm poly(methyl methacrylate) haptics and the other, a 1-piece hydrophobic acrylic IOL with 12.5 mm haptics. The amount of IOL decentration and tilt was quantitated using Purkinje reflections and photographic documentation at the last postoperative control. The results of the 2 groups were compared. RESULTS: Bag fixation of the IOL and an intact continuous curvilinear capsulorhexis (CCC) were confirmed in all cases at the last postoperative control, which was at a mean of 27.1 months +/- 5.4 (SD) and 26.7 +/- 4.4 months in the 3-piece group and 1-piece group, respectively (P = 0.659). There was no significant difference between groups in the percentage of patients with measurable tilt and decentration and of patients without measurable tilt and decentration (P = .956). The mean IOL tilt was 2.72 +/- 0.55 degrees in the 3-piece group and 2.70 +/- 0.84 degrees in the 1-piece group and the mean IOL decentration, 0.39 +/- 0.13 mm and 0.34 +/- 0.08 mm, respectively. There were no significant between-group differences in tilt or decentration (P = .897 and P = .103, respectively). CONCLUSION: There were no significant differences in tilt and decentration between 1-piece and 3-piece hydrophobic acrylic IOLs in eyes with capsular bag IOL implantation and an intact CCC.     

二次撕囊术在白内障超声乳化摘除及人工晶状体植入术中的应用

目的 :探讨在白内障超声乳化摘除及人工晶状体植入术中行二次撕囊术 (secondarycapsulorhexis)的方法和作用。方法 :对 6例因皮质膨胀或液化眼行计划性的二次撕囊 ;10例行非计划性的二次撕囊 ,其中 3例因撕囊口过小难于植入囊袋内位固定人工晶状体 ,3例因超声乳化白内障摘除时前囊膜切迹破裂 ,4例因撕囊口偏中心 ,为防止囊膜收缩综合征发生以致遮盖瞳孔区而行二次撕囊。结果 :二次撕囊术后完成前囊膜连续曲线形撕囊 13眼 ,16眼均植入囊袋内位固定人工晶状体。结论 :二次撕囊术可使晶状体皮质膨胀或液化的白内障眼易于完成前囊膜连续曲线形撕囊 ;可避免白内障术中前囊膜切迹破裂以至进一步放射状撕裂 ;可维持完整曲线形撕囊口边缘 ,防止发生人工晶状体植入后光学部偏中心 ,囊襻异位 ;使过小撕囊口易于植入囊袋内位固定人工晶状体 ;使撕囊口偏下而让难于被吸除的上方赤道部残收稿日期 :2 0 0 2 -0 3 -2 6;修回日期 :2 0 0 2 -0 6-0 4作者简介 :周坚强 ( 1973 -) ,男 ,嘉兴人 ,眼科医师。通信作者 :周坚强 (E -mail:zhjq @mail.jxptt.zj.cn)。余皮质易于被吸除 ;可减少或避免过小前囊膜撕囊口或明显偏中心撕囊口发生囊膜收缩综合征 (capsulecontractionsyn drome)等。     

Intraocular lens decentration and posterior capsule opacification: anatomo-pathologic findings after implantation of AMOSI40 IOLS

PURPOSE: To evaluate the incidence of intraocular lens (IOL) decentration and posterior capsule opacification (PCO) after implantation of a three-piece posterior chamber silicone IOL in a series of eyes examined postmortem. METHODS: Twenty-three pseudophakic enucleated human cadaver eyes, implanted with AMO SI40NB IOLs after phacoemulsification, were analyzed. Eyes obtained postmortem were sectioned at the equatorial plane and the anterior segment photographed from a posterior view. Location of IOL optic and haptics, type of fixation, and centration of IOL was evaluated. PCO was graded and the presence of Nd:YAG laser posterior capsulotomy was noted. RESULTS: Mean age at the time of surgery was 77.83 years, mean time since implantation was 18.26 months. In all the eyes examined, IOL haptics were positioned in the capsular bag. Mean decentration was 0.20+/-0.16 mm. No correlation was found between IOL decentration and time since implantation. The degree of peripheral PCO ranged from none (13.0%) to mild (39.1%) to moderate (26.1%) to severe (21.7%). The degree of central PCO ranged from none (52.2%) to mild (30.4%) to moderate (4.3%). Three patients (13.0%) underwent Nd:YAG laser posterior capsulotomy. CONCLUSIONS: A very good centration can be obtained when silicone AMOSI40NB IOLs are correctly implanted with the haptics inside the capsular bag. About half of the implants showed no central PCO while Nd:YAG laser posterior capsulotomy rates documented a relatively low PCO 18 months after surgery. A careful in the bag haptics placement is needed in order to reduce the IOL decentration and to prevent central PCO.     

Managing anterior capsule contraction by mechanical widening with vitrector-cut capsulotomy

We present a technique, vitrectorhexis, in which a vitrector-cut capsulotomy is used to treat anterior capsule contraction syndrome. A vitrector handpiece is used to remove all fibrous capsule tissue and residual lens epithelial cells from the anterior chamber. Vitrectorhexis may be an alternative to neodymium:YAG laser capsulotomy as it decreases the risk of radial tear extension to the zonules and of secondary IOL decentration. The technique was used in a 77-year-old man with capsulorhexis contraction syndrome and extensive fibrosis after phacoemulsification with silicone piggyback intraocular lens implantation. One day postoperatively, visual acuity improved from 20/60 to 20/30 and the anterior chamber reaction was minimal. At 1 month, best corrected visual acuity was 20/20. The IOL was well centered at 6 months.     

Nd:YAG激光后囊膜切开术对人工晶状体位置的影响:基于CASIA2的研究

目的　使用新型眼前节OCT CASIA2评估Nd:YAG 激光后囊膜切开术治疗后囊膜混浊（PCO）对人工晶状体（IOL）稳定性的影响。方法　前瞻性自身对照研究。纳入于川北医学院附属医院眼科诊断为PCO拟行Nd:YAG激光后囊膜切开术的患者，分别于激光前、激光后1 h、激光后1个月进行视力、眼压、眼前节和眼底检查，并使用CASIA2测量IOL倾斜和偏心的大小、方向，以及前房深度（ACD）。结果　本研究共纳入33例33眼患者，裸眼视力和最佳矫正视力分别从激光前的（0.771±0.375）logMAR和（0.608±0.369）logMAR提高到激光后1个月的（0.347±0.271）logMAR和（0.094±0.095）logMAR（均为P<0.001）。散瞳状态下，激光前、激光后1 h、激光后1个月IOL的倾斜度分别为（4.482±1.408）°、（4.541±1.343）°、（4.458±1.399）°,IOL的偏心量分别为（0.176±0.107）mm、（0.193±0.117）mm、（0.180±0.114）mm。激光前与激光后相比，IOL倾斜度和偏心量的差异均无统计学意义（均为P>0.05）。散瞳与非散瞳状态比较，IOL倾斜度和偏心量的差异均无统计学意义（均为P>0.05）。散瞳状态下ACD激光前为（3.842±0.278）mm，激光后1 h增加了0.019 mm，激光后1个月增加了0.012 mm，激光前后ACD相比,差异均有统计学意义（均为P<0.05）。结论　Nd:YAG激光后囊膜切开术是治疗PCO安全有效的方法，术后患眼视力显著提高，手术对IOL倾斜和偏心无明显影响，但可能造成IOL一定程度的轴向移位。     

Analysis of the capsule edge after Fugo plasma blade capsulotomy, continuous curvilinear capsulorhexis, and can-opener capsulotomy

PURPOSE: To compare the quality of the edges of anterior capsulotomies performed in porcine eyes using 3 different techniques. SETTING: David J. Apple, MD Laboratories for Ophthalmic Devices Research, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah, USA. METHODS: Four porcine eyes were submitted to the center in 10% neutral buffered formalin. The cornea of the eyes had been removed, and a continuous capsulotomy had been performed in each eye using the Fugo plasma blade. To provide morphologic correlation, 4 additional porcine eyes were used in the study. In 2, a manual continuous curvilinear capsulorhexis (CCC) was performed after the cornea or cornea/iris was removed and in the other 2, a can-opener capsulotomy (COC) was performed. The eyes were then placed in 10% neutral buffered formalin. Gross (macroscopic) and microscopic analysis of each eye was performed, and photographs were taken. One eye in each group was also prepared and analyzed under scanning electron microscopy (SEM). RESULTS: The capsulotomy margin in the Fugo blade group presented some regularly spaced tags directed centrally with smooth edges at the base. Such a configuration would not interfere with the dynamics of the capsulorhexis sphincter and would generally not lead to radial tears. The smooth and regular nature of the capsulotomy margin in the CCC group was confirmed by gross and microscopic examinations of the eyes. The capsulotomy margin in the COC group presented some sharp notches directed outward, irregularly spaced, and irregular in shape. These are known to have a tendency to extend and form radial tears. CONCLUSION: Although performance of an anterior capsulotomy with the Fugo blade was associated with some margin irregularities, the geometry of the centrally directed tags prevented them from becoming the site of radial tear formation. The base of the capsulotomy performed with the Fugo blade appeared to be almost as smooth and regular as in the CCC under SEM evaluation.     

Anterior capsule contraction and intraocular lens decentration and tilt after hydrogel lens implantation

AIM: To prospectively investigate changes in the area of the anterior capsule opening, and intraocular lens (IOL) decentration and tilt after implantation of a hydrogel IOL. METHODS: 100 patients underwent implantation of a hydrogel IOL in one eye and an acrylic IOL implantation in the opposite eye. The area of the anterior capsule opening, and the degree of IOL decentration and tilt were measured using the Scheimpflug videophotography system at 3 days, and at 1, 3, and 6 months postoperatively. RESULTS: The mean anterior capsule opening area decreased significantly in both groups. At 6 months postoperatively, the area in the hydrogel group was significantly smaller than that in the acrylic group. The mean percentage of the area reduction in the hydrogel group was also significantly greater than that in the acrylic group, being 16.9% in the hydrogel group and 8.8% in the acrylic group. In contrast, IOL decentration and tilt did not progress in either group. No significant differences were found in the degree of IOL decentration and tilt throughout the follow up period. CONCLUSIONS: Contraction of the anterior capsule opening was more extensive with the hydrogel IOL than with the acrylic IOL, but the degree of IOL decentration and tilt were similar for the two types of lenses studied.     

Intraocular lens centration with continuous tear capsulotomy

This study was designed to determine whether continuous tear capsulotomy was associated with improved posterior chamber lens centration. Two hundred eyes were divided into two subgroups of 100 patients each. In one subgroup a standard can-opener capsulotomy was performed and in the other, a continuous tear capsulotomy. All other factors including the cataract extraction technique, intraocular lens (IOL) style, the capsular bag placement of the IOL, and the use of viscoelastic material were constant. In this study, IOLs implanted after a continuous tear capsulotomy were found to center more reliably than IOLs implanted after a can-opener capsulotomy (P less than .01).     

Refraktion, Vorderkammertiefe, Dezentrierung und Tilt nach Implantation monofokaler und multifokaler Silikonlinsen

BACKGROUND: We prospectively investigated changes in refraction, anterior chamber depth, decentration and tilt after implantation of multifocal (MIOL) and monofocal (MONO) intraocular lenses (IOL). PATIENTS AND METHODS: We examined 103 cataractous eyes from 103 patients receiving either a three-piece monofocal or multifocal silicone IOL. Anterior chamber depth (ACD), amount of IOL decentration, and degree of IOL tilt were quantified using retroillumination and Scheimpflug photographs. Examinations, including subjective refraction, were performed preoperatively, one week and 6 months postoperatively. RESULTS: All eyes were within 2 dpt (spherical equivalent) from the target refraction, and 93% of eyes with a MIOL were within 1 dpt. No significant refractive shift or ACD change occurred during the postoperative course. Median tilt in the MIOL group at 6 months was 1.1 degrees (0-2.6) and that in the MONO group 1.0 degree (0-2.5). There was no statistically significant change in intraindividual IOL decentration or tilt. CONCLUSION: Three-piece silicone MIOLs and MONOs with polymethylmethacrylate haptics implanted in the capsular bag after circular capsulorhexis provide good centration and very little tilt without statistically significant change up to 6 months after surgery. Postoperative refractive shift is of minor concern for 6 months after surgery.     

Efficacy of haptic sutured in-the-bag intraocular lens for intraocular lens-capsule complex stability: a comparison of three insertion methods

AIM: To evaluate the efficacy and stability of haptic sutured in-the-bag intraocular lens (IOL) in eyes with zonular instability. METHODS: A total 60 eyes of 60 patients were included in this retrospective cohort study. Postoperative stability in three groups [haptic sutured IOL in the bag, IOL in the bag insertion with haptics oriented toward areas of zonulysis, IOL with capsular tension ring (CTR) in the bag insertion] were compared according to the IOL insertion methods. To evaluate the IOL stability, the changes of anterior chamber depth (ACD), refraction, contraction of anterior continuous curvilinear capsulotomy (CCC) area, and tilt of IOL were compared. RESULTS: There was no significant difference in change of ACD (-0.04±0.01 mm in group of haptic sutured IOL, -0.07±0.01 mm in group of CTR insertion) and refraction (0.05±0.05 D in group of haptic sutured IOL, 0.37±015 D in group of CTR insertion) between the group of haptic sutured IOL in the bag and CTR insertion group. But in comparison of CCC contraction and IOL tilt, CTR insertion group showed less contraction (1.00%±0.52%) and less IOL tilt (2.66°±0.11°) than the group of haptic sutured IOL in the bag (6.32%±1.36%, 3.47°±0.11°, respectively). The CTR insertion group showed the least CCC contraction and the least tilt. CONCLUSION: In eyes with zonular instability, the method of haptic sutured IOL in-the-bag shows comparable stability in ACD and refraction in comparison with IOL with CTR in the bag insertion. The method of IOL only in-the-bag insertion shows the largest contraction of CCC and the largest tilt of IOL.     

Femtosecond laser capsulotomy versus manual capsulotomy: a Meta-analysis

AIM: To perform a Meta-analysis on the precision and safety of femtosecond laser (FSL) capsulotomy compared with manual continuous curvilinear capsulotomy (CCC). METHODS: We searched PubMed, EMBASE, Web of Science, the Cochrane Library databases, and Clinical Trials.gov that maintained our inclusion criteria. Reference lists of retrieved articles were also reviewed. The effects of morphology of capsulorhexis and the tears of anterior capsule were calculated by using random-effect models. RESULTS: We identified 4 randomized and 7 nonrandomized studies involving 2941 eyes. The diameter of capsulotomy and the rates of anterior capsule tear showed no statistically difference between FSL group and manual group (MD=0.03; 95%CI, -0.03 to 0.09, P=0.31), and (OR=1.40; 95%CI, 0.28 to 6.97, P=0.68) respectively. In terms of the circularity of capsulotomy, FSL group had a more significant advantage than the manual CCC group (MD=0.09; 95%CI, 0.05 to 0.12, P<0.0001). CONCLUSION: Our Meta-analysis shows that FSL can perform a capsulotomy with more precision and higher reliability than manual CCC. The results in diameter of capsulotomy and the rate of anterior capsule tears was no significant difference between FSL and manual CCC groups. However in terms of circularity, the FSL was superior to the manual procedure.