应用PDE检测正常胎儿心脏各瓣口血流速度

本研究应用脉冲多普勒超声心动图（PDE）检测正常胎儿心脏各瓣口峰值血流速度。将100例胎儿按孕周20～40周分为五组。PDE检测结果表明：胎儿心脏动脉瓣口血流呈单峰频谱，房室瓣口血流呈双峰频谱（E峰、A峰）；各瓣口峰值血流速度随孕周而增加，与孕周呈正相关，有统计学意义（P＜0．05）。PDE对于检测胎儿心脏血流，评价胎儿心脏功能具有重要作用。     

正常胎儿出生前后心脏功能变化的分析

目的：探讨胎儿出生前后左右心室收缩及舒张功能的变化。资料与方法：本文分析５０例正常妊娠胎儿２０～４０周左右心室房室瓣口舒张期血流的Ａ／Ｅ比值及主、肺动脉瓣口血流速度的变化，同时比较１４例足月妊娠与４１例出生后新生儿的左右心室舒张收缩功能变化。结果：正常妊娠时，随孕周的增加左右心室房室瓣口血流速度Ａ／Ｅ比值逐渐降低，主动脉及肺动脉瓣口收缩期血流峰速逐渐增加。胎儿出生后左心室舒张期房室瓣口血流速度Ａ／Ｅ比值明显下降，主动脉瓣口血流峰速明显增快；右心室房室瓣口血流及肺动脉瓣口血流速度无明显变化。结论：正常妊娠期左右心室的舒张功能及收缩功能随孕周增加逐渐加强，胎儿出生后左心室舒张功能及收缩功能明显加强，而右心室舒张功能及收缩功能无变化。     

多普勒超声心动图对胎儿新生儿婴儿及幼儿心室舒张功能的评价

运用多普勒超声心动图分别检测胎儿、新生儿、婴儿及幼儿心室舒张功能。结果显示：胎儿左右房室瓣口血流ＰＦＶ、ＶＴＩ及ＰＰＧ均为Ｅ＜Ａ，左右心室舒张功能处于生理性非健全期；新生儿右房室瓣口血流转变为Ｅ＞Ａ，示右室松弛性的转变先于左室，心室舒张功能处于生理性过渡期；婴儿左右房室瓣口血流均为Ｅ＞Ａ，但ＭＶＯ比值较小，心室舒张功能处于正常过渡期；幼儿左右房室瓣口血流各项参数均为Ｅ＞Ａ，比值为ＭＶＯ＞ＴＶＯ，ＩＶＲＴ明显延长，表明人体心室舒张功能从此进入正常期。     

多普勒超声心动图对胎儿新生儿婴儿及幼儿心室舒张功能…

运用多普勒超声心动图分别检测胎儿、新生儿、婴儿及幼儿心室舒张功能。结果显示，胎儿左右房室瓣口血流ＰＦＶ、ＶＴＩ及ＰＰＧ均为Ｅ〈Ａ，左右心室舒张功能处于重量性非健全期；新生儿右房室瓣口血流转变为Ｅ〉Ａ，示右室松弛性的转变先于左室，心室舒张功能处于生理性过渡期；婴儿左右讣室瓣口血流均为Ｅ〉Ａ，但ＭＶＯ比值较小，心室舒张功能处于正常过渡期；幼儿左右房室瓣口血流各项参数均为Ｅ〉Ａ，比值为ＭＶＯ〉ＴＶＯ，Ｉ     

正常胎儿彩色多普勒超声心动图分析

目的获得正常胎儿心脏彩色多普勒超声心动图的各种参数。方法应用彩色多普勒超声诊断仪,对胎龄２０～４０周３００例正常胎儿的四腔室内径和各瓣口峰值血流速度进行了检测。结果胎儿心脏内径的大小与胎龄呈正相关,右心系统占优势。各瓣口峰值血流速度随胎龄的增加而升高,左室低于右室;房室瓣口呈双峰型频谱,Ｅ峰小于Ａ峰,而主、肺动脉瓣口呈单峰型频谱伴峰值前移,主动脉瓣口血流高于肺动脉。结论彩色多普勒超声心动图对于胎儿心脏的解剖结构和血流动力学检测具有很高的价值。     

产前超声检测中孕期胎儿心脏发育

目的 建立21~25孕周正常胎儿心脏解剖结构及血流动力学情况的正常参考值范围。方法 采用节段分析法对203胎中孕期(21~25周)正常妊娠单胎胎儿行超声心动图检查,测定心脏房室、肺动脉、主动脉、动脉导管内径及房室瓣血流速度、半月瓣血流速度、动脉导管血流速度及静脉导管血流速度。对各测量值与孕周行直线回归分析。结果 ①心脏各房室、大血管及动脉导管内径随孕周增加而增大;②肺动脉与升主动脉内径比值不随孕周改变;③房室瓣口血流峰值流速不随孕周改变;④三尖瓣及二尖瓣血流A峰大于E峰;⑤半月瓣口、动脉导管、静脉导管血流峰值流速随孕周增加而增大。结论 建立21~25孕周胎儿心血管各结构内径及血流动力学的正常参考值范围,可为筛查胎儿先天性心脏病提供参考。     

超声心动图房室平面位移测定器质性心脏病左室舒张功能的研究

目的探讨应用超声心动图房室平面位移（ＡＰＤ）测定法检测器质性心脏病左室舒张功能的诊断价值。方法设置４组：正常对照组２８例，冠心病组２４例，高心病组２２例，器质性房颤组１５例。每组先分别测定心脏形态学参数和收缩功能参数，包括房室内径，室壁厚度、射血分数、左室缩短分数、平均左室周径缩短率、每搏量，然后应用Ｍ型超声心动图分别测定各组左侧心脏总房室平面位移（ＴＡＰＤ）和心房收缩所致的房室平面位移（ＡＡＰＤ），计算出ＡＡＰＤ／ＴＡＰＤ的比值，同时根据二尖瓣血流频谱法测定Ａ峰和Ｅ峰，算出Ａ／Ｅ比值，最后用ｔ检验进行统计学显著性差异比较。结果器质性心脏病组ＴＡＰＤ和ＡＡＰＤ分别显著小于和大于对照组（Ｐ＜０．０１和Ｐ＜０．０５），ＡＡＰＤ／ＴＡＰＤ则显著大于对照组（Ｐ＜０．０１），而且各组ＡＡＰＤ／ＴＡＰＤ与多普勒二尖瓣血流频谱Ａ／Ｅ比值之间存在良好的线性关系。结论ＡＡＰＤ／ＴＡＰＤ是又一项无创伤性检测心室舒张功能的指标，且更具简便、实用的特点，很适合在无多普勒设备的基层医院推广应用。     

血浆代用品血定安和林格氏液对机体血液动力学影响的比较观察

目的：比较血定安和林格氏液对机体血流动力学的影响。方法：选择２０例硬膜外阻滞下行子宫切除术的患者，在平面固定于Ｔ６－Ｓ后分为血定安组（组１）和林格氏液组（组２）、用无创性连续心排血量监测仪（ＢＯＭＥＤ－ＮＣＣＯＭ－３）测定血流动力学数值。结果：两组患者心排血量（ＣＯ）、心脏指数（ＣＩ）、每搏量（ＳＶ）和每搏指数（ＳＩ）等指标在硬膜外阻滞平面固定后均有明显下降。但在组１快速输注血定安５００ｍｌ后这些     

经食管超声诊断先天性主动脉二叶式瓣的价值

目的： 探讨ＴＥＥ诊断先天性主动脉二叶式瓣（ＤＡＶ） 的价值。方法： 采用ＨＰ２５００超声诊断仪, 经胸超声（ＴＴＥ） 探头频率２．０～３．５ＭＨｚ, ＴＥＥ探头频率５．０ＭＨｚ。对ＴＴＥ拟诊的３３例ＤＡＶ患者ＴＥＥ做进一步复查, 重点观察主动脉长、短轴切面时主动脉瓣叶的数目、布局、形态、回声、启闭及血流动力学特点。结果： ＴＴＥ拟诊的３３例中有２４例被确诊, 并有１１ 例已经手术证实诊断正确。ＴＴＥ拟诊的其余９例中１例为四叶瓣, ８例为三叶瓣, ＴＴＥ误诊率为２７．２８％ 。结论： ＴＥＥ诊断先天性主动脉二叶式瓣的准确性大大高于ＴＴＥ, 为该病明确诊断和内外科选择治疗方案等有重要价值。     

多普勒超声测舒张早期室内充盈减射评价左室舒张功能

应用多普勒测量正常人及扩张型心肌病和缺血性心肌病患者舒张早期血流速度在左室内的改变，以估测此种改变对判断左室舒张功能的价值。结果表明：正常组二尖瓣及瓣下１ｃｍ、２ｃｍ、３ｃｍ处心室内不同部位的舒张早期充盈速度（Ｅ０、Ｅ１、Ｅ２、Ｅ３）及各点与瓣尖速度比值（Ｅ１／Ｅ０、Ｅ２／Ｅ０、Ｅ３／Ｅ０）均无统计学差异。而扩张型心肌病和缺血性心肌病患者Ａ／Ｅ＞１、器质性房颤及Ａ／Ｅ＜１“假性正常化”分组中一般Ｅ２开始降低，Ｅ３显著降低Ｅ３／Ｅ０比值与Ｅ１／Ｅ０比较存在差异（Ｐ值＜０．０５；Ｐ值＜０．０１）。同时Ｅ３速度及Ｅ３／Ｅ０比值与对照组比较存在差异。作者认为多普勒测量舒张早期左室血流充盈减射可用于评价左室舒张功能。     

超声心动图研究正压通气对犬心功能的影响及其机制

目的观察正压通气时心内瓣口血流速度和左、右心功能的变化,研究正压通气影响血流动力学机制的新理论。方法11条杂种犬,用超声心动图测定正压通气时心内各瓣口的血流速度,右室、左室每搏量,左室容积和射血分数的变化。结果三尖瓣和肺动脉瓣口血流速度正压吸气相减低,呼气相增加;二尖瓣和主动脉瓣口血流速度变化与之相反(P<0.05)。与自主呼吸相比,正压吸气时,右室每搏量减少,左室舒张末和收缩末容积减小,射血分数降低(P<0.05)。结论正压通气使室间隔趋于右移,同时,肺血管床回心血量增加,但与自主呼吸时相比,腔静脉回心血量相对减少,故心功能降低。     

室间隔完整的肺动脉闭锁的产前超声诊断

目的探讨室间隔完整的肺动脉闭锁的胎儿期超声诊断声像特征、检测技巧及其鉴别诊断,提高此类畸形的产前检出率。 方法对33200例胎儿均采取胎儿心脏四腔心切面加胎儿头侧偏转法获得四腔心切面及左右心室流出道及主、肺动脉长轴切面快速筛查胎儿心脏畸形,对疑有胎儿心脏畸形者则更行详细的胎儿彩色多普勒超声心脏检查。分析8例产前及产后诊断的室间隔完整的肺动脉闭锁的声像特征和病理特征。 结果产前共诊断室间隔完整的肺动脉闭锁8例,其主要声像特征是8例均有肺动脉内径细小,彩色多普勒于三血管气管平面显示7例动脉导管内血流反向,7例右室右房扩大,6例右室壁厚,7例中重度三尖瓣反流,1例三尖瓣下移畸形,1例三尖瓣狭窄并右室小。 结论肺动脉内径细小、不同程度的右房右室扩大、三尖瓣畸形、右室发育不良、动脉导管内血流反向是肺动脉闭锁的主要声像特征,三血管气管平面是产前超声诊断室间隔完整的肺动脉闭锁的关键切面,需注意与主动脉闭锁、永存动脉干进行鉴别。     

The spectrum of left ventricular filling in severe aortic stenosis

To assess left ventricular diastolic filling in valvular aortic stenosis, pulsed Doppler echocardiography was used prospectively in 35 patients with severe aortic stenosis (valve area < 1 cm²) and in 38 age-matched normal subjects. Twenty-seven patients had a normal left ventricular systolic function at rest (ejection fraction > 0.50) and a normal or only slightly increased mean pulmonary capillary wedge pressure (mean 11±4 mm Hg). Eight patients had a poor left ventricular systolic function (ejection fraction: 0.28±0.10) and an elevated mean pulmonary capillary wedge pressure (mean: 36±9 mm Hg). The Doppler derived filling parameters were correlated with hemodynamic data, left ventricular wall thickness derived from M-mode echocardiograms, heart rate and atrio-ventricular (A-V) conduction delay using stepwise multiple correlation. The data of this study suggest that left ventricular filling is significantly impaired in patients with severe aortic stenosis and left ventricular hypertrophy with an increase in late diastolic (A-wave) velocity, an increase in the A/E ratio, a decrease in the first one-half filling fraction and a prolongation of early diastolic deceleration time. These changes in filling hemodynamics are associated with alterations in mean pulmonary capillary wedge pressure, left ventricular wall thickness, heart rate and A-V conduction delay. When heart failure develops as a result of impaired left ventricular systolic function, an increase in left atrial filling pressure is associated with a shift of left ventricular filling towards early diastole with a ‘normalisation’ of the transmitral flow velocity curve. In extreme cases, a progression towards a ‘restrictive’ filling pattern is found with a marked shortening of the left ventricular early diastolic deceleration time. In the presence of high filling pressures, increased left atrial driving pressure (derived from the mean pulmonary capillary wedge pressure) is associated with changes in the left ventricular filling pattern irrespective of the presence and the degree of myocardial hypertrophy.     

超声心动图对糖尿病孕妇胎儿肺静脉血流频谱的动态研究

目的对糖尿病孕妇胎儿肺静脉血流频谱进行动态观察,并与正常胎儿比较,为糖尿病孕妇胎儿左心室舒张功能评价提供客观依据。方法分别在妊娠20～28周、32～38周,应用胎儿超声心动图观察34例糖尿病孕妇和54例正常孕妇的胎儿心脏结构。探测胎儿肺静脉、二尖瓣血流,测量肺静脉S波(收缩期峰值速度)、D波(舒张期峰值速度)、A谷(心房收缩波速度),二尖瓣E峰速度、A峰速度,并计算肺静脉S/D值及二尖瓣E/A值。结果无论在中孕期或晚孕期,研究组肺静脉血流频谱S/D值、A谷速度与正常对照组比较差异有显著性意义(P<0.05),而常规采用的二尖瓣血流E/A值两组间差别无显著性意义(P>0.05)。结论糖尿病孕妇胎儿左室舒张功能在中孕期及晚孕期均已发生改变;胎儿肺静脉血流频谱S/D值、A谷速度较二尖瓣血流E/A值能更敏感地反映胎儿左室舒张功能的变化。     

经腹部超声心动图在孕早期胎儿先天性心脏病诊断中的应用价值

目的探讨经腹部超声心动图在孕早期胎儿先天性心脏病（CHD）诊断中的应用价值。 方法对2012年6月至2015年4月在南京军区福州总医院产前检查的1 288例高危孕妇孕早期（孕13周）胎儿行超声心动图检查,分析孕早期胎儿CHD超声表现及其特征,追踪所有入选孕妇的妊娠过程及胎儿临床结局。 结果经腹部超声心动图在1288例胎儿中诊断CHD 16例（1.2%,16/1288）,其中复杂型CHD 11例,单纯型CHD 5例。孕早期胎儿CHD超声心动图表现：（1）法洛四联症2例,超声心动图显示主动脉轻度增宽,未见明显骑跨,室间隔缺损,肺动脉狭窄,远端显示不清。（2）左心发育不良综合征2例,孕13周超声心动图显示左心明显缩小,右心扩大,二尖瓣闭锁,室间隔缺损,主动脉轻度狭窄伴血流速度加快,肺动脉增宽。（3）大动脉共干I型2例,超声心动图显示心底部仅见1条大血管,未见明显分支血管,并见室间隔缺损。（4）完全型房室间隔缺损4例,超声心动图显示心内膜正常十字交叉结构消失,房室共瓣。（5）单心室1例,超声心动图未见室间隔回声,仅见一单心室。（6）主动脉缩窄1例,孕13周超声心动图显示心内结构正常,主动脉内径正常;孕16周超声心动图显示左心偏小,主动脉峡部轻度狭窄。（7）室间隔缺损4例,超声心动图显示室间隔连续中断,断端边缘回声增强。1例小的室间隔缺损误诊,漏诊室间隔缺损和永存左上腔静脉各1例。超声诊断CHD后孕妇选择终止妊娠11例,出生5例,随访结果与产前诊断均相符。 结论经腹部超声心动图可早期诊断多数胎儿CHD,尤其表现为四腔心异常的CHD,但对CHD异常大血管起源、分支及走向的显示存在一定困难,有待中孕期进一步确诊,早孕期经腹部超声心动图检查有重要临床应用价值。     

小鼠心血管超声生物显微镜显像与磁共振成像的对照研究

目的 探索超声生物显微镜显像(UBM)进行小鼠心血管成像的方法和常用切面观,并通过磁共振(MR)成像印证UBM所显示的解剖结构,探讨UBM在小鼠心血管成像中的可行性及应用价值.方法 采用Signo 3.0T磁共振(MR)成像系统对2只C57BL/6健康成年雄性小鼠进行胸部成像.选择C57BL/6健康成年雄性小鼠16只,采用Vevo 770小动物超声成像系统,经胸骨左缘、心尖、胸骨右缘及胸骨上窝等扫查窗口,观察并分析小鼠心脏及大血管的结构及血流频谱并对左心收缩及舒张功能进行评价.结果 小鼠胸部MR成像的解剖特征:心脏大部分位于左侧胸腔,心脏的长轴与身体的长轴线的角度约为45°.左房、左室、二尖瓣和右室位于胸部中线的左侧,主动脉瓣口及升主动脉、右房和三尖瓣位于胸部中线的右侧.UBM显像能获得左室长轴、左室短轴、右室流人道、心尖四腔、肺动脉长轴、升主动脉长轴、主动脉弓长轴、主动脉短轴等切面观,能显示并测量左房、左室、二尖瓣、主动脉及主动脉弓、室间隔、右房、右室、三尖瓣、肺动脉、无名动脉及左颈总动脉等结构,并可顺利获得各瓣口的血流频谱.对不同周龄小鼠测量数据进行比较,各组间差异无统计学意义.结论 UBM显像采用适当的扫查窗口和切面观能显示止常小鼠心脏和主动脉的形态结构和血流动力学状态,为基因敲除鼠动脉粥样硬化模型的研究奠定了基础.     

Blood flow velocity waveforms of the fetal pulmonary artery and the ductus arteriosus: reference ranges from 13 weeks to term.

OBJECTIVE: To establish reference ranges for blood flow velocity waveforms of the fetal main pulmonary artery and the ductus arteriosus during the second and third trimesters of pregnancy. METHODS: A prospective cross-sectional echocardiographic study was performed in 222 normal fetuses from 13 to 41 weeks of gestation using high resolution/color Doppler ultrasound equipment. RESULTS: Gestational age-specific reference ranges are given for peak velocity across the pulmonary valve, velocities in the ductus arteriosus, peak systolic velocity in the ductus arteriosus-to-peak velocity across the pulmonary valve ratio, ductal systolic velocity-to-diastolic velocity ratio, ductal resistance index and ductal pulsatility index. In the ductus arteriosus, increasing fetal heart rate was significantly associated with increasing end-diastolic velocity and decreasing systolic-to-diastolic ratio, decreasing resistance index, and decreasing pulsatility index. CONCLUSIONS: Based on a prospective study in more than 200 normal fetuses, the data provide gestational age specific reference ranges for blood flow velocity waveforms of the fetal pulmonary artery and the ductus arteriosus. The reference ranges may be helpful in prenatal diagnosis of cardiac malformations and ductal obstruction from 13 to 41 weeks of gestation.     

Doppler velocimetry of normal human fetal venous intrapulmonary branches.

OBJECTIVES: To describe the nature of flow velocity waveforms from fetal middle and distal venous pulmonary branches in the second half of normal pregnancy in relation to gestation, and to test repeatability and interrelationships of flow velocity waveform recordings from proximal, middle and distal venous pulmonary branches. DESIGN: Cross-sectional study. SUBJECTS/METHODS: A total of 111 normal singleton pregnancies between 20 and 40 weeks' gestation were studied using a color-coded Doppler ultrasound system. Pulmonary waveforms were obtained at the level of the fetal cardiac four-chamber view. Repeatability was tested from two recordings at 15-min time intervals in 25 separate normal pregnancies. RESULTS: The nature of middle and distal venous pulmonary flow velocity waveforms was comparable with that of proximal waveforms. Acceptable repeatability of pulmonary venous flow velocity waveforms with coefficients of variation below 15% was established for nearly all velocity parameters and their ratios. A gestational age-dependent change was found for all flow velocity waveform parameters including pulsatility index for veins at both middle and distal venous levels. Significant inter-pulmonary changes were observed for nearly all pulmonary venous waveform parameters. CONCLUSIONS: It is speculated that increase in volume flow and venous pulmonary pressure gradient plays a role in gestational age-dependent changes, whereas changes in vessel diameter and distance between the heart and more distal venous pulmonary vessels are responsible for inter-pulmonary changes.     

Systemic assessment of fetal hemodynamics by Doppler ultrasound

The aim of our study was to investigate the parameters of fetal circulation of normal pregnancies and their relationship to fetal cardiac output. We performed a cross-sectional study of 315 normal singleton pregnancies between 20 and 40 weeks' gestation without fetal chromosomal or structural malformations. After follow-up to delivery, 212 patients who fit all the criteria were enrolled for final analysis. Blood flow velocity waveforms were obtained from the tricuspid and mitral ventricular inflow, ascending aorta (AAO), pulmonary artery (PA), middle cerebral artery (MCA), renal artery (RA), umbilical artery (UA), descending aorta (DAO), inferior vena cava (IVC) and ductus venosus (DV) using duplex (real-time Doppler) ultrasound (US) scanner. The peak velocity of DV, AAO, PA and MCA were also obtained. At the intracardiac level, the ratio of peak flow velocity of E wave to peak flow velocity of A wave (E:A ratio) of mitral valve (MV) increased more rapidly than tricuspid valve (TV) E:A ratio. For the great vessels, aortic peak velocity remained higher than the pulmonary peak velocity with advancing gestation. The cardiac output closely correlated to the cardiac compliance and flow resistance indices at arterial and venous level. The acceleration time in the fetal arteries increased with advancing gestation in AAO, PA, MCA and DAO, but it decreased in RA and kept constant in UA. In addition, the acceleration time of UA was unrelated to cardiac output. The changes of the fetal intracardiac, arterial and venous impedances were remarkable through the gestation and related to cardiac output. Fetal cardiac output correlated well with the changes of arterial resistance, except with the DAO. The ventricular compliance increased with advancing gestation, especially in the left side, and was highly related to the change of cardiac output. The acceleration time in major arteries positively correlated with the gestational age and cardiac output, except in UA and RA; this indicates the difference of the changes of mean arterial pressure in uteroplacental circulation, fetal organs and great vessels. In conclusion, the fetal cardiac output correlated well with the ventricular compliance and was influenced by both hemodynamic changes in peripheral resistance and mean arterial pressure.     

Gore-Tex在右心室流出道重建术中的应用

目的探讨0.1 mm厚聚四氟乙烯(Gore-Tex)片制作肺动脉单瓣跨环补片重建右心室流出道的近中期临床疗效。方法76例合并肺动脉狭窄或畸形的先天性心脏病患儿,其中法洛四联症(tetralogy of Fallot,TOF)合并肺动脉狭窄55例,TOF合并Ⅰ型肺动脉闭锁7例,TOF合并肺动脉瓣缺如5例,右心室双出口合并肺动脉狭窄3例,TOF行改良Blalock-Taussig分流术后6例(左侧改良Blalock-Taussig分流术5例,右侧1例),均行矫治术,术中使用Gore-Tex片制作肺动脉单瓣跨环补片重建右心室流出道。比较术前与术中停体外循环后血氧饱和度、肺动脉干直径等差异,随访观察手术效果。结果76例均顺利完成手术,体外循环时间118(109,134)min,主动脉阻断时间86(77,102)min,术后呼吸机辅助时间88(45,99)h,ICU停留时间135(114,161)h;术后因心包压塞急诊二次手术1例,发生一过性低心排血量综合征2例、心律失常2例、肺部感染1例,均经对症治疗后恢复;1例室间隔微小残余分流(流速<2.5 m/s),术后6个月自行闭合。术中停体外循环后血氧饱和度[96.00(94.00,97.00)%]较术前[84.00(78.00,89.00)%]增高,肺动脉干直径[12.00(10.12,13.00)mm]较术前[6.60(5.80,7.50)mm]增加,肺动脉瓣压差[21.00(16.00,27.00)mm Hg]、肺动脉瓣上流速[2.31(2.00,2.70)m/s]较术前[86.00(72.00,94.75)mm Hg、4.60(4.20,5.10)m/s]降低(P<0.05)。术后随访3~48个月,超声心动图示73例肺动脉瓣瓣叶活动良好,开启闭合正常;3例轻度肺动脉瓣狭窄,随访期间未见进一步加重;5例肺动脉瓣轻度关闭不全;均无肺动脉单瓣的撕裂、黏连、增厚、钙化、血栓形成及感染等。结论右心室流出道重建中术应用Gore-Tex片制作肺动脉单瓣有较好的近中期抗反流作用,可改善右心功能。