原发性胃恶性淋巴瘤64例临床特点及内镜下表现回顾性分析

目的 对原发性胃恶性淋巴瘤的临床特点及内镜下表现进行回顾性分析以提高对该病诊治的认识.方法 回顾性分析64例原发性胃恶性淋巴瘤患者的临床特点、内镜表现、病理结果.结果本组病例中,45例出现中上腹痛,内镜表现中以溃疡型多见,全部病理结果均为B细胞非霍奇金淋巴瘤.结论 原发性胃恶性淋巴瘤是以胃肠道症状为主,发病部位以胃体及胃窦部多见,病理类型主要为B细胞非霍奇金淋巴瘤.     

结肠原发性恶性淋巴瘤26例诊治分析

目的：探讨结肠原发性恶性淋巴瘤的临床特点、诊断及治疗。方法回顾性分析26例结肠原发性恶性淋巴瘤的临床资料。结果26例主要表现为腹痛、腹胀,均为非霍奇金淋巴瘤。内镜活检确诊率为38.46％。接受手术及化疗的患者病情均有不同程度好转。结论结肠原发性恶性淋巴瘤的临床表现缺乏特异性,误诊率高,手术加化疗治疗本病疗效较好。     

原发性肾非霍奇金淋巴瘤2例临床分析

目的 探讨原发性肾非霍奇金淋巴瘤的临床特征.方法 分析2例原发性肾非霍奇金淋巴瘤患者的临床资料,并进行组织形态学观察和免疫组织化学检测及诊治经验总结.结果 2例患者诊断为原发性肾非霍奇金淋巴瘤,临床表现无特异性,1例为肾非霍奇金淋巴瘤并孤立肾患者放弃治疗,随访3个月,死于家中;1例行肾脏根治性切除术联合术后化疗后病情好转.结论 原发性肾非霍奇金淋巴瘤是一种罕见的、恶性程度较高的肿瘤,诊断依赖于组织病理学及免疫组织化学标记检查.术前确诊原发性肾非霍奇金淋巴瘤可避免手术,联合化疗和放疗应为治疗首选.     

原发性胃肠道恶性淋巴瘤的诊治分析

目的　提高原发性胃肠道恶性淋巴瘤的认识和诊治水平。方法　回顾分析 2 0例原发性胃肠道恶性淋巴瘤患者的临床资料。结果　 2 0例均经手术治疗。腹痛、消瘦、贫血及腹部包块为常见表现 ;肿瘤部位最多见于胃及回盲部 ;术前确诊 8例均为内镜下确诊。病理类型均为非霍奇金氏淋巴瘤 ,其中T细胞型 4例 ,B细胞型 16例。 17例行辅助CHOP化疗 ,有效率 90 %。结论　早期诊断困难 ,手术方式与其它癌肿术式相似 ,手术与术后化疗为主要治疗措施 ,病理类型与预后关系密切     

原发性胃非霍奇金淋巴瘤的诊断与手术治疗

目的 探讨原发性胃非霍奇金淋巴瘤的临床诊断方法 与手术治疗的疗效.方法 回顾性分析32例原发性胃非霍奇金淋巴瘤的临床特征及手术治疗情况.结果 临床表现主要为腹痛、消瘦、腹部肿块及上消化道出血;术前确诊率:胃镜活检72%,消化道造影25%,CT 38%;术前误诊率为28%;术后组织标本幽门螺杆菌(HP)检出阳性率为84%.行根治性手术24例,全胃切除术3例,剖腹探查活检术3例,所有病例术后都明确病理分型及免疫组化结果 .结论 原发性胃非霍奇金恶性淋巴瘤临床表现无特异性,术前确诊率低,胃镜及病理活检是主要的检查手段;外科手术是原发性胃非霍奇金恶性淋巴瘤的重要治疗方法 ,该病常通过外科手术获得组织学诊断和分型;HP感染是原发性胃黏膜相关组织淋巴瘤的一个重要致病因素,应重视抗HP治疗.     

原发性肾非霍奇金淋巴瘤临床分析

目的 探讨原发性肾非霍奇金淋巴瘤的临床特征。方法 分析2例原发性肾非霍奇金淋巴瘤病例资料，并进行组织形态学观察和免疫组织化学检测。结果 2例患者诊断为原发性肾非霍奇金淋巴瘤，临床上无特异性，1例患者死亡，1例术后行化疗联合放疗后病情好转。结论 原发性肾非霍奇金淋巴瘤是一种罕见的、恶性程度较高的肿瘤，诊断依赖于组织病理学及免疫组织化学标记检查。术前确诊原发性肾非霍奇金淋巴瘤可避免手术，联合化疗和放疗应为治疗首选。     

原发性胃肠道非霍奇金淋巴瘤临床特点及预后因素分析

目的:探讨影响原发性胃肠道非霍奇金淋巴瘤(PGI-NHL)患者的预后因素。方法:回顾性分析52例原发性胃肠道非霍奇金淋巴瘤患者的病例资料,观察其临床分期、病理组织类型、治疗方式与生存预后的关系。结果:单因素分析结果显示临床分期、病理分型、治疗模式是影响患者预后的因素。结论:临床分期、病理分型及治疗模式是影响原发性胃肠道非霍奇金淋巴瘤患者预后的独立危险因素。     

原发性胃恶性淋巴瘤的诊治

目的探讨原发性胃恶性淋巴瘤的诊治方法。方法回顾性分析16例原发性胃恶性淋巴瘤的诊断和治疗。结果16例患者均为非霍奇金淋巴瘤，术前明确诊断2例。16例均实施手术切除，根治性切除13例，姑息性切除3例。结论熟悉胃恶性淋巴瘤临床特点，通过胸片、内窥镜等检查提高对本病的认识，降低误诊率。采用以手术为主，化疗为辅的综合治疗可提高疗效。     

原发性胃肠道恶性淋巴瘤25例临床分析

目的总结原发性胃肠道恶性淋巴瘤（pri mary gastrointestinal malignant lymphoma,PGI ML）的临床特点、诊断和治疗经验。方法对我院1999年1月~2009年3月经手术治疗的25例原发性胃肠道恶性淋巴瘤临床资料、随访结果进行回顾性分析。结果25例原发性胃肠道恶性淋巴瘤主要表现为腹痛、腹块、消化道症状、发热等;术前误诊率较高;所有患者均行剖腹探查,其中根治性手术18例,姑息性手术5例,肿块活检术2例;随访3个月~10年,随访19例,10例死于复发转移。结论原发性胃肠道恶性淋巴瘤的临床表现缺乏特异性,手术加放、化疗的综合治疗疗效较好。     

原发性肺非霍奇金淋巴瘤临床分析

目的 探讨原发性肺非霍奇金淋巴瘤的临床特点.方法 回顾性分析1例原发性非霍奇金淋巴瘤患者的临床资料并结合文献.结果 患者临床主要症状:发热伴咳嗽、咳痰1个月.经电子支气管镜活检结合免疫组织化学确诊为非霍奇金恶性淋巴瘤.病理表现为大细胞间变性,裸细胞型.结论 原发性肺非霍奇金淋巴瘤无特异临床症状,需病理检查确诊,应引起临床重视.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.