强脉冲光治疗高原地区面部皮肤光老化168例临床疗效观察

目的探讨强脉冲光治疗高原面部皮肤光老化的临床疗效。方法将2015年5月至2017年5月期间我科门诊治疗的168例高原面部皮肤光老化患者采用强脉冲光子嫩肤仪分别用不同的波长,脉冲宽度,延迟时间,能量密度下进行治疗。结果患者在合适的治疗参数下经过5至7次治疗后,其中面部色素沉着的患者有效率为72.1%、面部毛细血管扩张的患者有效率84.7%、面部皮肤粗糙伴有细小皱纹的患者有效率91.4%。结论使用强脉冲光子嫩肤技术治疗高原面部皮肤光老化疗效确切,不良反应小,安全性较高,复发率低,值得临床推广应用。     

应用强脉冲光治疗面部皮肤色斑并改善皮肤整体状况

目的：探讨应用强脉冲光（IPL）治疗面部皮肤色斑及改善皮肤整体状况的疗效。方法：对474例面部色斑患者采用强脉冲光子嫩肤仪进行治疗。结果：色斑治疗有效率,患者评价89.0%,医生评价89.7%,医患双方评价合并后89.3%;面部皮肤状况整体改善率,患者评价94.7%,医患双方评价95.0%,医患双方评价合并后94.8%。疗效肯定,并发症发生率低（1.5%）。结论：应用IPL技术治疗面部皮肤色斑及改善皮肤状况,效果满意,治疗过程无创伤,无痛苦,无结痂,无色素沉着,不需休假,是一种安全、有效和方便的治疗方法。     

光子嫩肤技术应用于面部美容的临床观察

目的探讨应用光子嫩肤技术对面部美容的临床疗效。方法采用光子嫩肤仪某些特定波长的光对150例光老化和光损伤及毛细血管扩张等面部皮肤疾患进行非介入性治疗。对面部光老化及光损伤等皮损的治疗效果进行观察、分析。结果经4-6次治疗后,痊愈者22例,占14.6%;显效者86例,占57.3%;有效者34例,占22.7%;无效者8例,占5.3%。结论光子嫩肤技术对面部皮肤因光老化和光损伤以及血管扩张引起的病变疗效确切,美容效果肯定,损伤轻,痛苦小,操作简单,是值得推广应用的面部美容技术。     

光子嫩肤1300例疗效观察

目的探讨应用光子嫩肤技术对患者进行面部皮肤美容的综合临床效果。方法用光子嫩肤仪特定宽光谱的强脉冲光能够穿透皮肤,被组织中的色素团及血管优先选择性吸收,在不能破坏正常皮肤的前提下,使血管凝固,色素团、色素细胞破裂、分解,从而达到治疗毛细血管扩张,色素斑的效果。结果因皮肤出现簌簌沉着或微血管异常而引起的问题,如各种色斑、痣、血管瘤、静脉曲张等1 300例的治疗,总有效率达到90%以上。结论是非介入方法以适应不同皮肤状态的高新技术。     

用光子嫩肤技术治疗面部皮肤光老化的疗效观察

目的：探讨用光子嫩肤技术治疗面部皮肤光老化的临床效果。方法：对2009年8月～2011年4月期间我院收治100例面部皮肤光老化患者的临床资料进行回顾性研究。在这100例患者中,有51例患者存在面部细小皱纹的症状,有69例患者存在面部毛细血管扩张的症状,有90例患者存在面部色素沉着的症状,所有患者均存在面部皮肤质地粗糙的症状。我们使用Quantum SR 型光子嫩肤仪对这100例患者进行了治疗。结果：存在面部细小皱纹的患者治疗的总有效率为80%,存在面部毛细血管扩张的患者治疗的总有效率为78.3%,存在面部色素沉着的患者治疗的总有效率为81.1%,存在面部皮肤质地粗糙的患者治疗的总有效率为83%。结论：用光子嫩肤技术治疗面部皮肤光老化效果好,可有效地治疗面部细小皱纹、毛细血管扩张、色素沉着和皮肤质地粗糙等症状,而且安全性较高。此疗法值得在临床上推广使用。     

强脉冲光治疗面部色素性病变136例观察

目的：探讨强脉冲光对面部色素性病变的治疗效果。方法：采用采韵光子嫩肤仪波长为560nm—1200nm滤光片治疗136例面部色素性病变患者,治疗2次～6次,每次时间间隔为3W-5W,每位患者进行对比拍照、记录参数并进行临床疗效评估。结果：128例患者中各种病变的显效率分别：雀斑77．8％（70／90）,痤疮后色素沉着斑点80％（8／10）,扁平疣色素沉着80％（4／5）,老年斑62．5％（5／8）,咖啡斑50％（4／8）,黄褐斑效果不明显。结论：强脉冲光对雀斑、痤疮后色素沉着斑、扁平疣色素沉着有良好的疗效。     

强脉冲光子对面部激素依赖性皮炎的治疗

探讨强脉冲光子技术对面部激素依赖性皮炎的治疗效果.方法 对92例面部激素依赖性皮炎急性炎症消退后的患者进行强脉冲光治疗,6次治疗结束6月后进行疗效评价.结果 痊愈26例(28.3%),显效46例(50.0%),有效14例(15.2%),总有效率为93.5%.72例痊愈及显效患者随访结果,出现症状反复者12例.全部病例未出现不良反应.结论 强脉冲光子嫩肤技术治疗面部激素依赖性皮炎疗效明显,无不良反应.     

光子嫩肤技术治疗色素斑及面部毛细血管扩张症临床疗效分析

黄褐斑、咖啡斑、雀斑、酒渣鼻、老年斑以及外伤后的色素沉着等面部色素疾病和毛细血管扩张症在临床上较为常见。传统通过手术治疗,或者冷冻疗法、放射性同位素治疗以及二氧化碳激光疗法等,已经取得一定的疗效,但是并发症较多,有可能出现色素减退或沉着、皮肤萎缩和瘢痕等。彩光脉冲光子嫩肤技术是在低能量密度下采取连续波长的强脉冲光进行的一种治疗,这种治疗具有无侵入性、无剥蚀性的特点,不良反应较小,其实为光子脉冲技术的改进版,是一项近年开放的用于肺损伤性面部皮肤美容新技术,其利用光子具有不同波长以及不同能量的色彩光对皮肤细胞产生特定的治疗效果。     

强脉冲光治疗面部色素斑及毛孔粗大177疗效观察

与单一波长的激光治疗相比,强脉冲光具有更为广泛的适应证,因此光子嫩肤美容技术作为一种新颖的、非损伤性皮肤光损伤及光老化的治疗方法,在美容医疗领域已开辟出了新的应用前景.我科采用光子嫩肤仪对单纯雀斑、黄褐斑、复杂色斑及面部毛孔粗大等患者进行治疗,取得了较好的效果,现作一回顾性分析,报道如下.     

光子嫩肤1500例疗效观察

目的探讨应用光子嫩肤技术对患者进行面部皮肤美容的综合临床效果。方法采用光子嫩肤仪宽光谱(560-1200nm)作用皮肤色基产生综合生物疗效，达到皮肤美容的目的。结果应用光子嫩肤技术对混合性色斑、毛细血管扩张、细小皱纹、毛孔粗大等共1500例的治疗，总有效率达到90％以上。结论光子嫩肤技术疗效确切、安全省时，是具有一定治疗范围的高新技术。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.