高压氧治疗对新生儿缺氧缺血性脑病微循环的影响和分析

目的:研究高压氧对新生儿缺血缺氧性脑病(HIE)微循环的影响。方法:对65例新生儿HIE随机分为常规治疗组30例和高压氧治疗组35例,分别于生后24小时和10天进行耳廓微循环动态检测。同时设对照组13例正常新生儿。结果:新生儿HIE红细胞聚集率、渗出、出血率、白色微小血栓出现率较正常新生儿差异均有统计学意义。高压氧组较常规组有利于改善患儿细胞聚集率,白色微小血栓出现率。结论:高压氧治疗新生儿HIE并动态进行耳廓微循环检测对判断病情和疗效有临床价值。     

甲皱微循环检查在肿瘤治疗中的应用（附119例血瘀证病例观察）

为探讨肿瘤患者甲皱微循环改变与病情变化的相关性，应用甲皱微循环检查技术观察了血瘀证患者（肿瘤患者）１１９例的中西医结合治疗效果。结果：①在１１９例患者中９９１６％患者存在不同程度的微循环障碍，尤以血液流变学改变明显，表现在血液流速减慢，红细胞聚集加重，符合中医血瘀证判断；②恶性肿瘤临床症状变化多与微循环变化呈同步改变，微循环障碍程度越重，临床病势越重，预后也越不理想；③中药治疗可使７０％的恶性肿瘤患者临床症状及微循环状态得到改善。认为中西医结合治疗恶性肿瘤效果优于单纯西药治疗；甲皱微循环检查技术敏感而直观，在临床监测病情变化中可提供参考依据，值得推广使用。     

高压氧对新生儿缺氧缺血性脑病微循环的影响

目的 :研究高压氧对新生儿缺氧缺血性脑病微循环的影响。方法 :对 71例新生儿缺氧缺血脑病随机分组 ,予常规治疗或加用高压氧治疗 ,应用耳廓微循环检测技术分别于生后 2 4小时、48小时、72小时、10日进行微循环动态监测。结果 :新生儿缺氧缺血脑病红细胞聚集率、白色微小血栓出现率 ,均有显著性的异常改变。结论 :在常规治疗基础上加用高压氧治疗有利于改善细胞聚集率、白色微小血栓出现率 ,动态进行微循环检测对病情的评价、治疗方案的选择有临床实用价值。     

中西医结合治疗盆腔瘀血证30例临床观察

目的:探讨治疗盆腔瘀血证的有效方法.方法:将30例盆腔瘀血证患者采用中西药结合治疗,观察其临床疗效和治疗前后甲皱微循环、血液流变学指标的变化.结果:治疗后随着甲皱微循环、血液流变学指标的改善,临床症状和体征都得到相应好转.总有效率100%.结论:本法有改善微循环、改变患者血液"高凝状态"的作用.     

蛇毒抗栓酶对原发性高血压患者甲皱微循环及血液流变学影响的观察

对50例不同期的原发性高血压患者应用蛇毒抗栓酶进行治疗,治疗前后分别进行了甲皱微循环及血液流变学观察,结果表明:蛇毒抗栓酶可显著改善患者的甲皱微循环,主要表现为管袢较前清晰,袢顶渗出、扩张显著减轻、输入动脉与输出静脉之比恢复正常,血流加速,流态明显改善。血液流变学亦有明显改善,临床症状好转。     

重症结脑高颅压介入治疗和改善微循环治疗中的护理

重症结脑高颅压介入治疗和改善微循环治疗中的护理刘玉梅赵桂兰王东华（中国人民解放军第２５１医院０７５０００）我科自１９９０～１９９６年间收治重症结脑高颅压病人２３例，其中１４例意识障碍，经介入和改善微循环治疗使病情转危为安，成活好转者１７例，死亡６例。...     

调内消癖丸对小鼠耳廓微循环的影响

目的观察词内消癖丸活血化瘀、促进小鼠耳廓毛细血管开放，改善微循环的功能，探讨调内消癖丸对小鼠耳廓微循环的影响。方法采用直接给药的试验方法。结果调内消癖丸能促进小鼠耳廓毛细血管开放，改善微循环（P＜0．05，P＜0．01，P＜0．001）。结论调内消癖丸能活血化瘀、改善微循环为临床用药提供依据。     

鼻部、耳廓断裂伤的Ⅰ期修复及再植

目的 探讨治疗耳廓、鼻部断裂伤Ⅰ期修复的方法。方法耳廓鼻部断裂后严格清洗消毒，对位缝合或游离再植，细线缝合，加高压氧及给予改善微循环药物治疗。结果除2例耳廓断离伤未愈外，余54例修复及再植成功。结论严格清洗消毒创面，对位缝合，高压氧及治疗改善微循环药物治疗对耳廓鼻部断裂伤的Ⅰ期修复有较好的疗效。     

早期实施血液灌流治疗重症胰腺炎疗效观察

目的：探讨早期血液灌流术对重症胰腺炎的治疗作用。方法：重症胰腺炎患者20例,首先给予常规内科治疗,在循环相对稳定后即早期给予血液灌流,每次2小时,根据病情重复3～6次。结畏：20例重症急性胰腺炎患者最多经6次血液灌流后病情均明显稳定。全部病例经内科治疗后均痊愈出院。结论：早期使用血液灌流治疗重症胰腺炎,能够有效缓解临床症状,改善内环境及使微循环稳定,降低死亡率,改善预后,值得在临床上使用。     

复方独活糖浆药效学实验研究

目的：研究复方独活糖浆的药效学作用,为临床应用提供理论依据.方法：采用肾上腺素致小鼠耳廓微循环障碍,用测微尺测量微血管动脉和静脉管径、观察红细胞的流速;大鼠棉球肉芽肿,对0.6%醋酸致小鼠疼痛反应实验.结果：与空白对照组比较,复方独活糖浆各剂量组给药可明显增大小鼠耳廓微动脉和微静脉管径,加快血管内红细胞流速,改善小鼠耳廓微循环;可抑制大鼠棉球肉芽肿,对0.6%醋酸所致小鼠疼痛有明显镇痛作用.结果：复方独活糖浆经口服给药可明显增加肾上腺素所致微循环障碍小鼠耳廓微动脉及静脉管径,加微血管内RBC流速,改善小鼠耳廓微循环;抑制大鼠棉球肉芽肿,对0.6%醋酸所致小鼠疼痛有明显镇痛作用.结论：复方独活糖浆有抗炎镇痛、明显改善微循环作用.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.